Using microRNAs to enhance the generation of induced pluripotent stem cells

Current Protocols in Stem Cell Biology

Volumn 1, Issue SUPPL.20, 2012, Pages

  Li, Zhonghan ^a   Rana, Tariq M ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Embryonic body; iPSC; MicroRNA; Reprogrammingm; Teratoma

Indexed keywords

MICRORNA;

ANIMAL; ANIMAL EMBRYO; ARTICLE; CLONOGENIC ASSAY; CULTURE TECHNIQUE; CYTOLOGY; EMBRYOID BODY; FEMALE; FIBROBLAST; GENETICS; METABOLISM; METHODOLOGY; MOUSE; NUCLEAR REPROGRAMMING; NUDE MOUSE; PATHOLOGY; PLURIPOTENT STEM CELL; TERATOMA;

ANIMALS; CELL CULTURE TECHNIQUES; COLONY-FORMING UNITS ASSAY; EMBRYO, MAMMALIAN; EMBRYOID BODIES; FEMALE; FIBROBLASTS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, NUDE; MICRORNAS; NUCLEAR REPROGRAMMING; TERATOMA;

EID: 84864148010     PISSN: 19417322     EISSN: 19388969     Source Type: Journal    
DOI: 10.1002/9780470151808.sc04a04s20     Document Type: Article

References (22)

1. Aoi, T., Yae, K., Nakagawa, M., Ichisaka, T., Okita, K., Takahashi, K., Chiba, T., and Yamanaka, S. 2008. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321:699-702.
2. Giorgetti, A., Montserrat, N., Aasen, T., Gonzalez, F., Rodriguez-Piza, I., Vassena, R., Raya, A., Boue, S., Barrero, M.J., Corbella, B.A., Torrabadella, M., Veiga, A., and Izpisua Belmonte, J.C. 2009. Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2. Cell Stem Cell 5:353-357.
3. Ichida, J.K., Blanchard, J., Lam, K., Son, E.Y., Chung, J.E., Egli, D., Loh, K.M., Carter, A.C., Di Giorgio, F.P., Koszka, K., Huangfu, D., Akutsu, H., Liu, D.R., Rubin, L.L., and Eggan, K. 2009. A small-molecule inhibitor of Tgf-beta signaling replaces Sox2 in reprogramming by inducing nanog. Cell Stem Cell 5:491-503.
4. Itzhaki, I., Maizels, L., Huber, I., Zwi-Dantsis, L., Caspi, O., Winterstern, A., Feldman, O., Gepstein, A., Arbel, G., Hammerman, H., Boulos, M., and Gepstein, L. 2011. Modeling the long QT syndrome with induced pluripotent stem cells. Nature 471:225-229.
5. Judson, R.L., Babiarz, J.E., Venere, M., and Blelloch, R. 2009. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat. Biotechnol. 27:459-461.
6. Latronico, M.V. and Condorelli, G. 2009. MicroRNAs and cardiac pathology. Nat. Rev. Cardiol. 6:419-429.
7. Li, Z., Yang, C.S., Nakashima, K., and Rana, T.M. 2011. Small RNA-mediated regulation of iPS cell generation. EMBO J. 30:823-834.
8. Lyssiotis, C.A., Foreman, R.K., Staerk, J., Garcia, M., Mathur, D., Markoulaki, S., Hanna, J., Lairson, L.L., Charette, B.D., Bouchez, L.C., Bollong, M., Kunick, C., Brinker, A., Cho, C.Y., Schultz, P.G., and Jaenisch, R. 2009. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proc. Natl. Acad. Sci. U.S.A. 106:8912-8917.
9. Maherali, N. and Hochedlinger, K. 2009. Tgf-beta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc. Curr. Biol. 19:1718-1723.
10. Marchetto, M.C., Carromeu, C., Acab, A., Yu, D., Yeo, G.W., Mu, Y., Chen, G., Gage, F.H., and Muotri, A.R. 2010. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 143:527-539.
11. Meissner, A., Wernig, M., and Jaenisch, R. 2007. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat. Biotechnol. 25:1177-1181.
12. Nakagawa, M., Koyanagi, M., Tanabe, K., Takahashi, K., Ichisaka, T., Aoi, T., Okita, K., Mochiduki, Y., Takizawa, N., and Yamanaka, S. 2008. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26:101-106.
13. Park, I.H., Zhao, R., West, J.A., Yabuuchi, A., Huo, H., Ince, T.A., Lerou, P.H., Lensch, M.W., and Daley, G.Q. 2008. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451:141-146.
14. Shi, Y., Zhao, Y., and Deng, H. 2010. Powering reprogramming with vitamin C. Cell Stem Cell 6:1-2.
15. Subramanyam, D., Lamouille, S., Judson, R.L., Liu, J.Y., Bucay, N., Derynck, R., and Blelloch, R. 2011. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat. Biotechnol. 29:443-448.
16. Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-872.
17. Takahashi, K. and Yamanaka, S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-676.
18. Wang, Y., Baskerville, S., Shenoy, A., Babiarz, J.E., Baehner, L., and Blelloch, R. 2008. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat. Genet. 40:1478-1483.
19. Xu, N., Papagiannakopoulos, T., Pan, G., Thomson, J.A., and Kosik, K.S. 2009. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 137:647-658.
20. Yazawa, M., Hsueh, B., Jia, X., Pasca, A.M., Bernstein, J.A., Hallmayer, J., and Dolmetsch, R.E. 2011. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 471:230-234.
21. Yu, J., Vodyanik, M.A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J.L., Tian, S., Nie, J., Jonsdottir, G.A., Ruotti, V., Stewart, R., Slukvin, I.I., and Thomson, J.A. 2007. Induced pluripotent stem cell lines derived from human somatic cells. Science 318:1917-1920.
22. Zhang, J., Lian, Q., Zhu, G., Zhou, F., Sui, L., Tan, C., Mutalif, R.A., Navasankari, R., Zhang, Y., Tse, H.F., Stewart, C.L., and Colman, A. 2011. A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects. Cell Stem Cell 8:31-45.