Cell-cell interaction with APC, not IL-23, is required for naive CD4 cells to acquire pathogenicity during Th17 lineage commitment

Journal of Immunology

Volumn 189, Issue 3, 2012, Pages 1220-1227

  Shi, Guangpu ^a   Lovaas, Jenna D ^a   Tan, Cuiyan ^a   Vistica, Barbara P ^a   Wawrousek, Eric F ^a   Aziz, Mehak K ^a   Rigden, Rachael C ^a   Caspi, Rachel R ^a   Gery, Igal ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CD28 ANTIGEN; CD3 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 6; LYSOZYME; MONOCLONAL ANTIBODY; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL INTERACTION; CELL LINEAGE; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; EYE INFLAMMATION; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH17 CELL; TRANSGENIC MOUSE;

ANIMALS; ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELL LINEAGE; CELLS, CULTURED; COCULTURE TECHNIQUES; DENDRITIC CELLS; EYE DISEASES; INFLAMMATION; INTERLEUKIN-23; MICE; MICE, TRANSGENIC; MURAMIDASE; TH17 CELLS;

EID: 84864146194     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103033     Document Type: Article

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