Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: In vitro evaluation

International Journal of Pharmaceutics

Volumn 434, Issue 1-2, 2012, Pages 169-174

  Montenegro, Lucia ^a   Sinico, Chiara ^b   Castangia, Ines ^b   Carbone, Claudia ^a   Puglisi, Giovanni ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Idebenone; Skin delivery; Skin penetration; Skin permeation; Solid lipid nanoparticles

Indexed keywords

IDEBENONE; NONIONIC SURFACTANT; SOLID LIPID NANOPARTICLE;

ARTICLE; CHROMATOGRAPHY; DRUG DELIVERY SYSTEM; DRUG TARGETING; FEASIBILITY STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; SKIN; STRATUM CORNEUM; TEMPERATURE;

ANIMALS; ANTIOXIDANTS; CETOMACROGOL; DRUG DELIVERY SYSTEMS; ETHERS; FEASIBILITY STUDIES; LIPIDS; NANOPARTICLES; PARTICLE SIZE; PERMEABILITY; PLANT OILS; POLYETHYLENE GLYCOLS; SKIN ABSORPTION; SURFACE-ACTIVE AGENTS; SWINE; TISSUE DISTRIBUTION; UBIQUINONE;

EID: 84864125978     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.05.046     Document Type: Article

References (35)

1. E. Bernard, J.L. Dubois, and J. Wepierre Importance of sebaceous glands in cutaneous penetration of an antiandrogen: target effect of liposomes J. Pharm. Sci. 86 1997 573 578
2. F. Cilurzo, P. Minghetti, and C. Sinico Newborn pig skin as model membrane in in vitro drug permeation studies: a technical note AAPS Pharm. Sci. Technol. 8 2007 E94
3. F.L. Crane Biochemical functions of coenzyme Q10 J. Am. Coll. Nutr. 20 2001 591 598
4. G. Dallner, and P.J. Sindelar Regulation of ubiquinone metabolism Free Radic. Biol. Med. 29 2000 285 294
5. F. Dreher, and H.I. Maibach Protective effects of topical antioxidants in humans Curr. Probl. Dermatol. 29 2001 157 164
6. D.R. Friend In vitro skin permeation techniques J. Control. Release 18 1992 235 248
7. 10, a cutaneous antioxidant and energizer Biofactors 9 1999 371 378
8. I. Imada, T. Fujita, Y. Sugiyama, K. Okamoto, and Y. Kobayashi Effects of idebenone and related compounds on respiratory activities of brain mitochondria, and on lipid peroxidation of their membranes Arch. Gerontol. Geriatr. 8 1989 323 341
9. P. Izquierdo, J. Feng, J. Esquena, T.F. Tadros, J.C. Dederen, M.J. Garcia, N. Azemar, and C. Solans The influence of surfactant mixing ratio on nano-emulsion formation by the PIT method J. Colloid Interface Sci. 285 2005 388 394
10. V. Jenning, M. Schäfer-Korting, and S. Cohla Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties J. Control. Release 66 2000 115 126
11. V.B. Junyaprasert, V. Teeranachaideekul, E.B. Souto, P. Boonme, and R.H. Müller Q10-loaded NLC versus nanoemulsions: stability, rheology and in vitro skin permeation Int. J. Pharm. 377 2009 207 214
12. M.K. Lee, S.J. Lim, and C.K. Kima Preparation, characterization and in vitro cytotoxicity of paclitaxel loaded sterically stabilized solid lipid nanoparticles Biomaterials 28 2007 2137 2146
13. B. Li, and Z.Q. Ge Nanostructured lipid carriers improve skin permeation and chemical stability of idebenone AAPS Pharm. Sci. Technol. 13 2012 276 283
14. J. Liu, W. Hu, H. Chen, Q. Ni, H. Xu, and X. Yang Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery Int. J. Pharm. 328 2007 191 195
15. G. Lukowski, J. Kasbohm, P. Pflegel, A. Illing, and H. Wulff Crystallographic investigation of cetylpalmitate solid lipid nanoparticles Int. J. Pharm. 196 2000 201 205
16. W. Mehnert, and K. Mäeder Solid lipid nanoparticles. Production, characterization and applications Adv. Drug Deliv. Rev. 47 2001 165 196
17. M. Mezei, E. Touitou, H.E. Junginger, N.D. Weiner, and T. Tagai Liposomes as carriers for topical and transdermal delivery J. Pharm. Sci. 9 1994 1189 1203
18. L. Montenegro, A. Trapani, A. Latrofa, and G. Puglisi In vitro evaluation on a model of blood brain barrier of idebenone-loaded solid lipid nanoparticles J. Nanosci. Nanotechnol. 12 2012 330 337
19. L. Montenegro, A. Campisi, M.G. Sarpietro, C. Carbone, R. Acquaviva, G. Raciti, and G. Puglisi In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain Drug Dev. Ind. Pharm. 37 2011 737 746
20. R.H. Müller, K. Maëder, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery: a review of the state of the art Eur. J. Pharm. Biopharm. 50 2000 161 177
21. D. Papakostas, F. Rancan, W. Sterry, U. Blume-Peytavi, and A. Vogt Nanoparticles in dermatology Arch. Dermatol. Res. 303 2011 533 550
22. J. Pardeike, A. Hommoss, and R.H. Müller Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products Int. J. Pharm. 366 2009 170 184
23. L. Schols, C.H. Meyer, G. Schmid, I. Wihelms, and H. Przuntek Therapeutic strategies in Friedreich's ataxia J. Neural Transm. Suppl. 68 2004 135 145
24. V.P. Shah, J. Elkins, S.Y. Lam, and J.P. Skelly Determination of in vitro drug release from hydrocortisone creams Int. J. Pharm. 53 1989 53 59
25. B. Siekmann, and K. Westesen Investigations on solid lipid nanoparticles prepared by precipitation in o/w emulsions Eur. J. Pharm. Biopharm. 43 1996 104 109
26. H. Sies Introductory remark H. Sies, Oxidative Stress 1985 Academic Press Orlando 1 7
27. S. Songkro, Y. Purwo, G. Becket, and T. Rades Investigation of newborn pig skin as an in vitro animal model for transdermal drug delivery STP Pharm. Sci. 13 2003 133 139
28. J.J. Thiele, F. Dreher, and L. Packer Antioxidant defence systems in skin P. Elsner, H. Maibach, A. Rougier, Drugs in Cosmetic: Cosmeceuticals? 2000 Dekker New York 145 187
29. J.J. Thiele, M.G. Traber, and L. Packer Depletion of human stratum corneum vitamin E: an early and sensitive in vivo marker of UV-induced photooxidation J. Invest. Dermatol. 110 1998 756 761
30. M. Trotta Influence of phase transformation on indomethacin release from microemulsions J. Control. Release 60 1999 399 405
31. J.-J. Wang, K.-S. Liu, K.C. Sung, C.-Y. Tsai, and J.-Y. Fang Lipid nanoparticles with different oil/fatty ester ratios as carriers of buprenorphine and its prodrugs for injection Eur. J. Pharm. Sci. 38 2009 138 146
32. K. Westesen, and H. Bunjees Do nanoparticles prepared from lipids solid at room temperature always possess a solid lipid matrix? Int. J. Pharm. 115 1995 129 131
33. E. Wieland, E. Schutz, V.W. Armstrong, F. Kuthe, C. Heller, and M. Oellerich Idebenone protects hepatic microsomes against oxygen radical-mediated damage in organ preservation solutions Transplantation 60 1995 444 451
34. S.A. Wissing, R.H. Muller, L. Manthei, and C. Mayer Structural characterization of Q10-loaded solid lipid nanoparticles by NMR spectroscopy Pharm. Res. 21 2004 400 405
35. J. Zhang, and E. Smith Percutaneous permeation of betamethasone 17-valerate incorporated in lipid nanoparticles J. Pharm. Sci. 100 2011 896 903