Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic

Journal of Immunology

Volumn 189, Issue 3, 2012, Pages 1467-1479

  Sacha, Jonah B ^a,b,c   Kim, In Jeong ^d   Chen, Lianchun ^d   Ullah, Jakir H ^e   Goodwin, David A ^e   Simmons, Heather A ^a   Schenkman, Daniel I ^a   Von Pelchrzim, Frederike ^e   Gifford, Robert J ^f   Nimityongskul, Francesca A ^a   Newman, Laura P ^a   Wildeboer, Samantha ^d   Lappin, Patrick B ^d   Hammond, Daisy ^d   Castrovinci, Philip ^a   Piaskowski, Shari M ^a   Reed, Jason S ^b   Beheler, Kerry A ^a   Tharmanathan, Tharsika ^d   Zhang, Ningli ^d   Muscat King, Sophie ^d   Rieger, Melanie ^e   Fernandes, Carla ^e   Rumpel, Klaus ^e   Gardner II, Joseph P ^d   Gebhard, Douglas H ^d   Janies, Juliann ^d   Shoieb, Ahmed ^e   Pierce, Brian G ^d   Trajkovic, Dusko ^d   Rakasz, Eva ^a   Rong, Sing ^d   McCluskie, Michael ^d   Christy, Clare ^d   Merson, James R ^d   Jones, R Brad ^g   Nixon, Douglas F ^f   Ostrowski, Mario A ^g   Loudon, Peter T ^e   Pruimboom Brees, Ingrid M ^e   Sheppard, Neil C ^d   more..

^a UNIVERSITY OF WISCONSIN   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d PFIZER INC   (United States)

^e PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; AUTOANTIGEN; DNA VACCINE; GAG PROTEIN; PLASMID DNA; VACCINE; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG SAFETY; ENDOGENOUS RETROTRANSPOSABLE ELEMENT; ENDOGENOUS RETROVIRUS; FEMALE; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNIZATION; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; LONG INTERSPERSED REPEAT; MALE; MALIGNANT TRANSFORMATION; MOUSE; NEOPLASM; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; RETROPOSON; RHESUS MONKEY; TISSUE INJURY; VACCINATION;

ADULT; AIDS VACCINES; AMINO ACID SEQUENCE; ANIMALS; CANCER VACCINES; DISEASE MODELS, ANIMAL; DNA TRANSPOSABLE ELEMENTS; ENDOGENOUS RETROVIRUSES; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; FEMALE; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HUMANS; MACACA MULATTA; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA;

EID: 84864123257     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200079     Document Type: Article

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