Paralogous outer membrane proteins mediate uptake of different forms of iron and synergistically govern virulence in Francisella tularensis tularensis

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 25191-25202

  Ramakrishnan, Girija ^a   Sen, Bhaswati ^a   Johnson, Richard ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE MUTANTS; FERRIC IRON; FERROUS IRON; FRANCISELLA TULARENSIS; HIGH AFFINITY; INTRACELLULAR PATHOGENS; IRON ACQUISITION; IRON-LIMITATION; MACROPHAGE-LIKE CELLS; MAMMALIAN HOSTS; MOUSE MODELS; OUTER MEMBRANE; OUTER MEMBRANE PROTEIN; PARALOGS; SIDEROPHORES; TRANSPORT ASSAYS; UPTAKE SYSTEMS; VIRULENCE FACTORS; VIRULENT STRAINS;

BIOLOGICAL MEMBRANES; MAMMALS; MERGERS AND ACQUISITIONS; PROTEINS;

IRON;

FERRIC ION; FSLE PROTEIN; FUPA PROTEIN; MUTANT PROTEIN; OUTER MEMBRANE PROTEIN; SIDEROPHORE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; BACTERIAL REPRODUCTION; BACTERIAL VIRULENCE; BINDING AFFINITY; CONTROLLED STUDY; FRANCISELLA TULARENSIS; IRON TRANSPORT; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TULAREMIA;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; CARRIER PROTEINS; CELL LINE; FRANCISELLA TULARENSIS; ION TRANSPORT; IRON; MACROPHAGES; MICE; MUTATION; SIDEROPHORES; TULAREMIA; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); FRANCISELLA; FRANCISELLA TULARENSIS; FRANCISELLA TULARENSIS SUBSP. TULARENSIS; MAMMALIA;

EID: 84864113215     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.371856     Document Type: Article

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