In vitro mechanistic study of cell death and in vivo performance evaluation of RGD grafted PEGylated docetaxel liposomes in breast cancer

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 8, Issue 6, 2012, Pages 951-962

  Naik, Sachin ^a   Patel, Deepa ^a   Chuttani, Krishna ^b   Mishra, Anil K ^b   Misra, Ambikanandan ^a  

^a M S UNIVERSITY OF BARODA   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

BT 20; Ehrlich ascites tumor; MDA MB 231; RGD; Supercritical fluid technology

Indexed keywords

BALB/C MICE; BASIC SCIENCE; BIODISTRIBUTIONS; BREAST CANCER; BREAST CANCER TREATMENT; BT-20; CELL LINES; CYTOTOXIC; DNA CONTENT; DOCETAXEL; DRUG CONCENTRATION; DRUG DISTRIBUTION; EQUIVALENT CONCENTRATIONS; IN-VITRO; IN-VIVO; INTRACELLULAR DRUG DELIVERY; LOW TOXICITY; MDA-MB-231; MECHANISTIC STUDIES; PERFORMANCE EVALUATION; PHARMACOKINETIC AND BIODISTRIBUTION STUDIES; PHASE ARREST; RGD; SITE-SPECIFIC; SUPERCRITICAL FLUID TECHNOLOGY; THERAPEUTIC AGENTS;

BIOCHEMISTRY; CELL CULTURE; CELL DEATH; CYTOTOXICITY; DISEASES; DRUG DELIVERY; EFFLUENT TREATMENT; GRAFTING (CHEMICAL); LIPOSOMES; POLYETHYLENE GLYCOLS; SUPERCRITICAL FLUIDS;

POLYETHYLENE OXIDES;

DOCETAXEL; LIPOSOME; MACROGOL; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CELL DEATH; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG FORMULARY; FEMALE; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; LIPOSOMES; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED BALB C; NANOCAPSULES; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS; RABBITS; TAXOIDS; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

MUS;

EID: 84864108557     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.11.008     Document Type: Article

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