Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo

Molecular Microbiology

Volumn 85, Issue 3, 2012, Pages 461-477

  Deshayes, Caroline ^a,e   Bielecka, Magdalena K ^a,e   Cain, Robert J ^a   Scortti, Mariela ^a,b   De las Heras, Aitor ^a   Pietras, Zbigniew ^c   Luisi, Ben F ^c   Núñez Miguel, Ricardo ^c   Vázquez Boland, José A ^a,d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF LEÓN   (Spain)

^e RSR Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP BINDING PROTEIN; LEUCINE; PHENYLALANINE; PROTEIN PRFA; TRANSCRIPTION FACTOR; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BINDING SITE; CELL VACUOLE; EPITHELIUM CELL; FEMALE; GENE ACTIVATION; GENE INDUCTION; IN VIVO STUDY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MACROPHAGE; MICROBIAL ATTENUATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN MOTIF; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BACTERIAL PROTEINS; BINDING SITES; CELL LINE; CYCLIC AMP; FEMALE; LISTERIA MONOCYTOGENES; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDE TERMINATION FACTORS; PHAGOSOMES; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; SEQUENCE ALIGNMENT; TRANSCRIPTIONAL ACTIVATION; VACUOLES; VIRULENCE;

LISTERIA; LISTERIA MONOCYTOGENES; MUS;

EID: 84864095821     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2012.08121.x     Document Type: Article

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