Synthetic human monoclonal antibodies toward staphylococcal enterotoxin B (SEB) protective against toxic shock syndrome

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 25203-25215

  Karauzum, Hatice ^a   Chen, Gang ^b   Abaandou, Laura ^a   Mahmoudieh, Mahta ^a   Boroun, Atefeh R ^a   Shulenin, Sergey ^a   Devi, V Sathya ^a   Stavale, Eric ^a   Warfield, Kelly L ^a   Zeitlin, Larry ^c   Roy, Chad J ^d   Sidhu, Sachdev S ^b   Aman, M Javad ^a  

^a Integrated BioTherapeutics Inc   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c Mapp Biopharmaceutical   (United States)

^d TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY MATURATION; ANTIGEN-BINDING; BINDING AFFINITIES; BIOWEAPONS; CLINICAL DEVELOPMENT; ESCHERICHIA COLI CELLS; IMMUNOTHERAPEUTICS; IN-VITRO; MAMMALIAN CELLS; NICOTIANA BENTHAMIANA; PHAGE DISPLAY TECHNOLOGY; STAPHYLOCOCCAL ENTEROTOXIN B; THERAPEUTIC EFFICACY; TOXIC SHOCKS;

BINDING ENERGY; BIOLOGICAL WEAPONS; ESCHERICHIA COLI; MONOCLONAL ANTIBODIES; PLANTS (BOTANY); TOXIC MATERIALS;

MAMMALS;

GAMMA INTERFERON; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G119 ANTIBODY; IMMUNOGLOBULIN G120 ANTIBODY; IMMUNOGLOBULIN G121 ANTIBODY; INTERLEUKIN 2; STAPHYLOCOCCUS ENTEROTOXIN B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE STORM; DRUG EFFICACY; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NICOTIANA BENTHAMIANA; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; TOXIC SHOCK SYNDROME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ENTEROTOXINS; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTERFERON-GAMMA; INTERLEUKIN-2; MICE; MICE, INBRED BALB C; RECOMBINANT PROTEINS; SHOCK, SEPTIC; TIME FACTORS; TOBACCO;

ESCHERICHIA COLI; MAMMALIA; MUS; NICOTIANA BENTHAMIANA;

EID: 84864089013     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.364075     Document Type: Article

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