Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal target

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 10, 2007, Pages 3537-3545

  Chayakulkeeree, Methee ^a,b   Rude, Thomas H ^a   Toffaletti, Dena L ^a   Perfect, John R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CERULENIN; COPPER; FATTY ACID SYNTHASE; FLUCONAZOLE; TETRATHIOMOLYBDIC ACID;

ARTICLE; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; CULTURE MEDIUM; DISEASE MODEL; FAS1 GENE; FAS2 GENE; FATTY ACID SYNTHESIS; FUNGAL GENE; FUNGAL STRAIN; FUNGICIDAL ACTIVITY; FUNGUS CULTURE; FUNGUS GROWTH; FUNGUS MUTANT; GENE EXPRESSION; GROWTH RATE; LUNG INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALS; ANTIBIOTICS, ANTIFUNGAL; ANTIFUNGAL AGENTS; AZOLES; BRAIN; CERULENIN; COLONY COUNT, MICROBIAL; COPPER; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DNA, FUNGAL; DRUG SYNERGISM; ENZYME INHIBITORS; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; ISOENZYMES; LUNG; MICE; MICROBIAL SENSITIVITY TESTS; PHENOTYPE; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 34948907855     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00442-07     Document Type: Article

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