Scube activity is necessary for Hedgehog signal transduction in vivo

Developmental Biology

Volumn 368, Issue 2, 2012, Pages 193-202

  Johnson, Jacque Lynne F A ^a   Hall, Thomas E ^b   Dyson, Jennifer M ^b   Sonntag, Carmen ^b   Ayers, Katie ^b   Berger, Silke ^a,b   Gautier, Philippe ^c   Mitchell, Christina ^b   Hollway, Georgina E ^a,d   Currie, Peter D ^a,b  

^a VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Hedgehog signaling; Muscle development; Zebrafish

Indexed keywords

MESSENGER RNA; SONIC HEDGEHOG PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENOTYPE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; IN VIVO STUDY; MOLECULAR CLONING; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SCUBE1 GENE; SCUBE3 GENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZEBRA FISH;

DANIO RERIO; ERINACEIDAE;

EID: 84864048458     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2012.05.007     Document Type: Article

References (50)

1. Aanstad P., Santos N., Corbit K.C., Scherz P.J., Le Trinh, Salvenmoser A., Huisken W., Reiter J., Stainier, D.Y.J.F. The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Curr. Biol. 2009, 19:1034-1039.
2. Ahuja R., Yammani R., Bauer J.A., Kalra S., Seetharam S., Seetharam B. Interactions of cubilin with megalin and the product of the amnionless gene (AMN): effect on its stability. Biochem. J. 2008, 410:301-308.
3. Bale A.E. Hedgehog signaling and human disease. Annu. Rev. Genomics Hum. Genet. 2002, 3:47-65.
4. Barresi M.J., Stickney H.L., Devoto S.H. The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity. Development 2000, 127:2189-2199.
5. Blagden C.S., Currie P.D., Ingham P.W., Hughes S.M. Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog. Genes Dev. 1997, 11:2163-2175.
6. Cohen M.M.J. The hedgehog signaling network. Am. J. Med. Genet. A 2003, 123A:5-28.
7. Concordet J.P., Lewis K.E., Moore J.W., Goodrich L.V., Johnson R.L., Scott M.P., Ingham P.W. Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development 1996, 122:2835-2846.
8. Corbit K.C., Aanstad P., Singla V., Norman A.R., Stainier D.Y., Reiter J.F. Vertebrate Smoothened functions at the primary cilium. Nature 2005, 437:1018-1021.
9. Currie P.D., Ingham P.W. Induction of a specific muscle cell type by a hedgehog-like protein in zebrafish. Nature 1996, 382:452-455.
10. Du S.J., Devoto S.H., Westerfield M., Moon R.T. Positive and negative regulation of muscle cell identity by members of the hedgehog and TGF-beta gene families. J. Cell. Biol. 1997, 139:145-156.
11. Evangelista M., Tian H., de Sauvage F.J. The hedgehog signaling pathway in cancer. Clin. Cancer Res. 2006, 12:5924-5928.
12. Grimmond S., Larder R., Van Hateren N., Siggers P., Hulsebos T.J., Arkell R., Greenfield A. Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1). Genomics 2000, 70:74-81.
13. Grimmond S., Larder R., Van Hateren N., Siggers P., Morse S., Hacker T., Arkell R., Greenfield A. Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development. Mech. Dev. 2001, 102:209-211.
14. Hammerschmidt M., Bitgood M.J., McMahon A.P. Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev. 1996, 10:647-658.
15. Hatta K., Bremiller R., Westerfield M., Kimmel C.B. Diversity of expression of engrailed-like antigens in zebrafish. Development 1991, 112:821-832.
16. Haycraft C.J., Banizs B., Aydin-Son Y., Zhang Q., Michaud E.J., Yoder B.K. Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet. 2005, 1:e53.
17. Hirsinger E., Stellabotte F., Devoto S.H., Westerfield M. Hedgehog signaling is required for commitment but not initial induction of slow muscle precursors. Dev. Biol. 2004, 275:143-157.
18. Hollway G.E., Maule J., Gautier P., Evans T.M., Keenan D.G., Lohs C., Fischer D., Wicking C., Currie P.D. Scube2 mediates Hedgehog signalling in the zebrafish embryo. Dev. Biol. 2006, 294:104-118.
19. Hooper J.E., Scott M.P. Communicating with Hedgehogs. Nat. Rev. Mol. Cell Biol. 2005, 6:306-317.
20. Huangfu D., Anderson K.V. Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development 2006, 133:3-14.
21. Hui C.C., Joyner A.L. A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat. Genet. 1993, 3:241-246.
22. Ingham P.W., McMahon A.P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001, 15:3059-3087.
23. Kang S., Graham J.M.J., Olney A.H., Biesecker L.G. GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome. Nat. Genet. 1997, 15:266-268.
24. Karlstrom R.O., Talbot W.S., Schier A.F. Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning. Genes Dev. 1999, 13:388-393.
25. Kawakami A., Nojima Y., Toyoda A., Takahoko M., Satoh M., Tanaka H., Wada H., Masai I., Terasaki H., Sakaki Y., Takeda H., Okamoto H. The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Curr. Biol. 2005, 15:480-488.
26. Kiernan J.A. Histological and Histochemical Methods, Theory and Practice 2005, Oxford University Press, New York.
27. Krauss S., Concordet J.P., Ingham P.W. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 1993, 75:1431-1444.
28. Lewis K.E., Currie P.D., Roy S., Schauerte H., Haffter P., Ingham P.W. Control of muscle cell-type specification in the zebrafish embryo by Hedgehog signalling. Dev. Biol. 1999, 216:469-480.
29. Mullor J.L., Sanchez P., Ruiz I., Altaba A. Pathways and consequences: Hedgehog signaling in human disease. Trends Cell Biol. 2002, 12:562-569.
30. Nieuwenhuis E., Hui C.C. Hedgehog signaling and congenital malformations. Clin. Genet. 2005, 67:193-208.
31. Ochi H., Westerfield M. Signaling networks that regulate muscle development: lessons from zebrafish. Dev. Growth Differ. 2007, 49:1-11.
32. Odenthal J., van Eeden F.J., Haffter P., Ingham P.W., Nüsslein-Volhard C. Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Dev. Biol. 2000, 219:350-363.
33. Oxtoby E., Jowett T. Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development. Nucleic Acids Res. 1993, 21:1087-1095.
34. Radhakrishna U., Wild A., Grzeschik K.H., Antonarakis S.E. Mutation in GLI3 in postaxial polydactyly type A. Nat. Genet. 1997, 17:269-271.
35. Roessler E., Belloni E., Gaudenz K., Jay P., Berta P., Scherer S.W., Tsui L.C., Muenke M. Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nat. Genet. 1996, 14:357-360.
36. Rohatgi R., Milenkovic L., Scott M.P. Patched1 regulates hedgehog signaling at the primary cilium. Science 2007, 317:372-376.
37. Sambrook J., Russell D.W. Molecular Cloning: a Laboratory Manual 2001, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
38. Scholpp S., Wolf O., Brand M., Lumsden A. Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon. Development 2006, 133:855-864.
39. Strähle U., Blader P., Ingham P.W. Expression of axial and sonic hedgehog in wildtype and midline defective zebrafish embryos. Int. J. Dev. Biol. 1996, 40:929-940.
40. Taipale J., Beachy P.A. The Hedgehog and Wnt signalling pathways in cancer. Nature 2001, 411:349-354.
41. Tsai M.T., Cheng C.J., Lin Y.C., Chen C.C., Wu A.R., Wu M.T., Hsu C.C., Yang R.B. Isolation and characterization of a secreted, cell-surface glycoprotein SCUBE2 from humans. Biochem. J. 2009, 422:119-128.
42. van Eeden F.J., Granato M., Schach U., Brand M., Furutani-Seiki M., Haffter P., Hammerschmidt M., Heisenberg C.P., Jiang Y.J., Kane D.A., Kelsh R.N., Mullins M.C., Odenthal J., Warga R.M., Allende M.L., Weinberg E.S., Nusslein-Volhard C. Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 1996, 123:153-164.
43. Vortkamp A., Gessler M., Grzeschik K.H. GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families. Nature 1991, 352:539-540.
44. Weinberg E.S., Allende M.L., Kelly C.S., Abdelhamid A., Murakami T., Andermann P., Doerre O.G., Grunwald D.J., Riggleman B. Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos. Development 1996, 122:271-280.
45. Wicking C., McGlinn E. The role of hedgehog signalling in tumorigenesis. Cancer Lett. 2001, 173:1-7.
46. Wolff C., Roy S., Ingham P.W. Multiple muscle cell identities induced by distinct levels and timing of Hedgehog activity in the zebrafish embryo. Curr. Biol. 2003, 13:1169-1181.
47. Woods I.G., Talbot W.S. The you gene encodes an EGF-CUB protein essential for Hedgehog signaling in zebrafish. PLoS Biol. 2005, 3:e66.
48. Wu B.T., Su Y.H., Tsai M.T., Wasserman S.M., Topper J.N., Yang R.B. A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones. J. Biol. Chem. 2004, 279:37485-37490.
49. Yammani R.R., Seetharam S., Seetharam B. Cubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomy. Am. J. Physiol. Endocrinol. Metab. 2001, 281:E900-7.
50. Yang R.B., Ng C.K., Wasserman S.M., Colman S.D., Shenoy S., Mehraban F., Komuves L.G., Tomlinson J.E., Topper J.N. Identification of a novel family of cell-surface proteins expressed in human vascular endothelium. J. Biol. Chem. 2002, 277:46364-46373.