Susceptibility of gastric cancer according to leptin and leptin receptor gene polymorphisms in Korea

Journal of the Korean Surgical Society

Volumn 83, Issue 1, 2012, Pages 7-13

  Kim, Eun Young ^a   Chin, Hyung Min ^a   Park, Seung Man ^a,b   Jeon, Hae Myung ^a,c   Chung, Woo Chul ^a   Paik, Chang Nyol ^a   Jun, Kyong Hwa ^a  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Gastric cancer; Leptin; Leptin receptors

Indexed keywords

EID: 84864032171     PISSN: 12260053     EISSN: 20930488     Source Type: Journal    
DOI: 10.4174/jkss.2012.83.1.7     Document Type: Article

References (30)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32.
2. Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS. Role of leptin in fat regulation. Nature 1996;380:677.
3. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996;334:292-5.
4. Señarís R, Garcia-Caballero T, Casabiell X, Gallego R, Castro R, Considine RV, et al. Synthesis of leptin in human placenta. Endocrinology 1997;138:4501-4.
5. Jin L, Burguera BG, Couce ME, Scheithauer BW, Lamsan J, Eberhardt NL, et al. Leptin and leptin receptor expression in normal and neoplastic human pituitary: evidence of a regulatory role for leptin on pituitary cell proliferation. J Clin Endocrinol Metab 1999;84:2903-11.
6. Briscoe C P, Hanif S, Arch JR, Tadayyon M. Leptin receptor long-form signalling in a human liver cell line. Cytokine 2001;14:225-9.
7. Mix H, Widjaja A, Jandl O, Cornberg M, Kaul A, Goke M, et al. Expression of leptin and leptin receptor isoforms in the human stomach. Gut 2000;47:481-6.
8. Schneider R, Bornstein SR, Chrousos G P, Boxberger S, Ehninger G, Breidert M. Leptin mediates a proliferative response in human gastric mucosa cells with functional receptor. Horm Metab Res 2001;33:1-6.
9. Sierra-Honigmann MR, Nath AK, Murakami C, Garcia-Cardena G, Papapetropoulos A, Sessa WC, et al. Biological action of leptin as an angiogenic factor. Science 1998;281:1683-6.
10. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U. S. adults. N Engl J Med 2003;348:1625-38.
11. Stattin P, Lukanova A, Biessy C, Soderberg S, Palmqvist R, Kaaks R, et al. Obesity and colon cancer: does leptin provide a link? Int J Cancer 2004;109:149-52.
12. Stattin P, Soderberg S, Hallmans G, Bylund A, Kaaks R, Stenman UH, et al. Leptin is associated with increased prostate cancer risk: a nested case-referent study. J Clin Endocrinol Metab 2001;86:1341-5.
13. Stephenson GD, Rose D P. Breast cancer and obesity: an update. Nutr Cancer 2003;45:1-16.
14. Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, et al. Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996;379:632-5.
15. Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996;84:491-5.
16. Gotoda T, Manning BS, Goldstone AP, Imrie H, Evans AL, Strosberg AD, et al. Leptin receptor gene variation and obesity: lack of association in a white British male population. Hum Mol Genet 1997;6:869-76.
17. Zhao L, Shen ZX, Luo HS, Shen L. Possible involvement of leptin and leptin receptor in developing gastric adenocarcinoma. World J Gastroenterol 2005;11:7666-70.
18. Lewin MJ, Bado A. Gastric leptin. Microsc Res Tech 2001;53:372-6.
19. Ishikawa M, Kitayama J, Nagawa H. Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer. World J Gastroenterol 2006;12:5517-22.
20. Zhao X, Huang K, Zhu Z, Chen S, Hu R. Correlation between expression of leptin and clinicopathological features and prognosis in patients with gastric cancer. J Gastroenterol Hepatol 2007;22:1317-21.
21. Low S, Chin MC, Ma S, Heng D, Deurenberg-Yap M. Rationale for redefining obesity in Asians. Ann Acad Med Singapore 2009;38:66-9.
22. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995;1:1155-61.
23. Ben Ali S, Kallel A, Ftouhi B, Sediri Y, Feki M, Slimane H, et al. Association of G-2548A LEP polymorphism with plasma leptin levels in Tunisian obese patients. Clin Biochem 2009;42:584-8.
24. Mammes O, Betoulle D, Aubert R, Herbeth B, Siest G, Fumeron F. Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight. Ann Hum Genet 2000;64(Pt 5):391-4.
25. Bado A, Levasseur S, Attoub S, Kermorgant S, Laigneau JP, Bortoluzzi MN, et al. The stomach is a source of leptin. Nature 1998;394:790-3.
26. Blaser MJ, Atherton JC. Helicobacter pylori persistence: biology and disease. J Clin Invest 2004;113:321-33.
27. Azuma T, Suto H, Ito Y, Ohtani M, Dojo M, Kuriyama M, et al. Gastric leptin and Helicobacter pylori infection. Gut 2001;49:324-9.
28. Chung WK, Power-Kehoe L, Chua M, Chu F, Aronne L, Huma Z, et al. Exonic and intronic sequence variation in the human leptin receptor gene (LEPR). Diabetes 1997;46:1509-11.
29. Woo HY, Park H, Ki CS, Park YL, Bae WG. Relationships among serum leptin, leptin receptor gene polymorphisms, and breast cancer in Korea. Cancer Lett 2006;237:137-42.
30. Ogawa T, Hirose H, Yamamoto Y, Nishikai K, Miyashita K, Nakamura H, et al. Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population. Metabolism 2004;53:879-85.