Cyclic Fluid shear stress promotes osteoblastic cells proliferation through ERK5 signaling pathway

Molecular and Cellular Biochemistry

Volumn 364, Issue 1-2, 2012, Pages 321-327

  Li, Peng ^a   Ma, Yan Chao ^a   Sheng, Xiao Yun ^a   Dong, Hai Tao ^a   Han, Hua ^a   Wang, Jing ^a   Xia, Ya Yi ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Cyclic fluid shear stress; ERK5; Osteoblast; Proliferation

Indexed keywords

BIX 02189; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN P16; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CELL STRAIN 3T3; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLUID FLOW; OSTEOBLAST; PROTEIN EXPRESSION; SHEAR STRESS; SIGNAL TRANSDUCTION; TIME;

ANILINE COMPOUNDS; ANIMALS; CELL LINE; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; INDOLES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 7; OSTEOBLASTS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TRANSCRIPTION FACTOR AP-1;

EID: 84863984328     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1233-y     Document Type: Article

References (32)

1. Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H (2007) Akt1 in osteoblasts and osteoclasts controls bone remodeling. PLoS ONE 2:e1058
2. Reich KM, Gay CV, Frangos JA (1990) Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production. J Cell Physiol 143:100-104
3. Takai E, Mauck RL, Hung CT, Guo XE (2004) Osteocyte viability and regulation of osteoblast function in a 3D trabecular bone explant under dynamic hydrostatic pressure. J Bone Miner Res 19:1403-1410 (Pubitemid 41094341)
4. Basso N, Heersche JNM (2002) Characteristics of in vitro osteoblastic cell loading models. Bone 30:347-351 (Pubitemid 34150156)
5. Biewener AA, Taylor CR (1986) Bone strain: a determinant of gait and speed? J Exp Biol 123:383-400 (Pubitemid 16071463)
6. Myers KA, Rattner JB (2007) Osteoblast-like cells and fluid flow: cytoskeleton-dependent shear sensitivity. Biochem Biophys Res Commun 364:214-219 (Pubitemid 350001347)
7. Majima T, Marchuk LL, Sciore P, Shrive NG, Frank CB, Hart DA (2000) Compressive compared with tensile loading of medial collateral ligament scar in vitro uniquely influences mRNA levels for aggrecan, collagen type II, and collagenase. J Orthop Res 18:524-531
8. Kim IS, Song YM, Cho TH, Kim JY, Weber FE, Hwang SJ (2009) Synergistic action of static stretching and BMP-2 stimulation in the osteoblast differentiation of C2C12 myoblasts. J Biomech 42(16):2721-2727
9. Sakai K, Mohtai M, Iwamoto Y (1998) Fluid shear stress increases transforming growth factor beta 1 expression in human osteoblast-like cells: modulation by cation channel blockades. Calcif Tissue Int 63:515-520 (Pubitemid 28531802)
10. 2+-and ATP-dependent in MC3T3-E1 osteoblasts. Bone 42:644-652
11. Fukuno N, Matsui H, Kanda Y, Suzuki O, Matsumoto K, Sasaki K, Kobayashi T, Tamura S (2011) TGF-[beta]-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts. Biochem Biophys Res Commun 408:202-207
12. Lee J-D, Levtch RJU, Han J (1995) Primary structure of BMK1: a new mammalian MAP kinase. Biochem Biophys Res Commun 213:715-724
13. Pi X, Yan C, Berk BC (2003) Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circ Res 94:362-369
14. Dinev D, Jordan BWM, Neufeld B, Lee J-D, Lindemann D, Rapp SUR, Ludwig S (2001) Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells. EMBO Rep 2:829-834 (Pubitemid 32982752)
15. Mehta P, Jenkins B, McCarthy L, Thilak L, Robson C, Neal D, Leung H (2003) MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 exp ression and invasion. Oncogene 22:1381-1389 (Pubitemid 36384600)
16. Yan L, Carr J, Ashby PR, Murry-Tait V, Thompson C, Arthur JSC (2003) Knockout of ERK5 causes multiple defects in placental and embryonic development. BMC Dev Biol 3:11-31
17. Yan C, Takahashi M, Okuda M, Lee J-D, Berk C (1999) Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium. J Biol Chem 274:143-150 (Pubitemid 29035041)
18. Huang Y-C, Hung W-C, Chen W-T, Jiang W-H, Yu H-S, Chai C-Y (2011) Effects of MEK and DNMT inhibitors on arsenictreated human uroepithelial cells in relation to cyclin-D1 and p16. Toxicol Lett 200:59-66
19. Mulloy R, Salinas S, Philips A, Hipskind RA (2003) Activation of cyclin D1 expression by the ERK5 cascade. Oncogene 22:5387-5398 (Pubitemid 37072193)
20. Tatake RJ, O'Neill MM, Kennedy CA, Wayne AL, Jakes S, Wu D, Kugler SZ Jr, Kashem MA, Kaplita P, Snow RJ (2008) Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem Biophys Res Commun 377(1):120-125
21. Abe J-I, Kusuhara M, Ulevitch RJ, Berk BC, Lee J-D (1996) Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase. J Biol Chem 271:16586-16590 (Pubitemid 26239014)
22. Frangos JA, McIntire LV, Eskin SG (1987) Shear stress induced stimulation of mammalian cell metabolism. Biotechnol Bioeng 32:1053-1060
23. Hsieh T-P, Sheu S-Y, Sun J-S, Chen M-H (2011) Icariin inhibits osteoclast differentiation and bone resorption by suppression of MAPKs/NF-kB regulated HIF-1a and PGE2 synthesis. Phytomedicine 18:176-185
24. Keselowsky BG, Collard DM, García AJ (2005) Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation. Proc Natl Acad Sci 102:5953-5957 (Pubitemid 40594236)
25. Yang Q, Lee J-D (2011) Targeting the BMK1 MAP kinase pathway in cancer therapy. Neurosci Lett 494:38-43
26. Li L, Tatake RJ, Natarajan K, Taba Y, Garin G, Tai C, Leung E, Surapisitchat J, Yoshizumi M, Yan C, Abe J-I, Berk BC (2008) Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochem Biophys Res Commun 370:159-163
27. Jia X, Liu B, Shi X, Ye M, Zhang F, Liu H (2011) Roles of the ERK, JNK/AP-1/cyclin D1-CDK4 pathway in silica-induced cell cycle changes in human embryo lung fibroblast cells. Cell Biol Int 35:697-704
28. Coqueret O (2002) Linking cyclins to transcriptional control. Gene 299:35-55 (Pubitemid 35379826)
29. Nauman EA, Satcher RL, Keaveny TM, Halloran BP, Bikle DD (2001) Osteoblasts respond to pulsatile fluid flow with shortterm increases in PGE2 but no change in mineralization. J Appl Physiol 90:1849-1854 (Pubitemid 32336468)
30. Jacobsa CR, Yellowley CE, Davis BR, Zhou Z, Cimbala JM, Donahuea HJ (1998) Differential effect of steady versus oscillating flow on bone cells. J Biomech 11:969-976 (Pubitemid 28561790)
31. Hwang J, Ing MH, Salazar A, Lassègue B, Griendling K, Navab M, Sevanian A, Hsiai TK (2003) Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression implication for native LDL oxidation. Circ Res 93:1225-1232 (Pubitemid 37543063)
32. Young SRL, Hum JM, Rodenberg E, Turner CH, Pavalko FM (2011) Non-overlapping functions for Pyk2 and FAK in osteoblasts during fluid shear stress-induced mechanotransduction. Plos One 6:e16026