MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion

Oncogene

Volumn 22, Issue 9, 2003, Pages 1381-1389

  Mehta, P B ^a   Jenkins, B L ^a   McCarthy, L ^a   Thilak, L ^a   Robson, C N ^a   Neal, D E ^a   Leung, H Y ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

ERK5; MAPK; MEK5; Metastasis; Prostate cancer

Indexed keywords

GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

ARTICLE; CANCER INVASION; CANCER SURVIVAL; CELL PROLIFERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION; TUMOR GROWTH;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BONE NEOPLASMS; CELL DIVISION; CELL LINE; CELL MOVEMENT; COLLAGEN; DRUG COMBINATIONS; ENZYME INDUCTION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KIDNEY; LAMININ; MALE; MAP KINASE KINASE 5; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; PROTEOGLYCANS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TRANSCRIPTION FACTOR AP-1; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037422183     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206154     Document Type: Article

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