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Volumn 32, Issue 4, 2012, Pages 778-785

Autoantibodies and high-risk HLA susceptibility markers in first-degree relatives of brazilian patients with type 1 diabetes mellitus: A progression to disease based study

Author keywords

Autoantibodies; GAD65A; HLA DR DQ; IA2 A; IAA; Type I diabetes

Indexed keywords

AUTOANTIBODY; GLUTAMATE DECARBOXYLASE 65 ANTIBODY; HLA DQ ANTIGEN; HLA DR ANTIGEN; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN; INSULIN ANTIBODY; INSULINOMA ASSOCIATED ANTIGEN 1 AUTOANTIBODY; ISLET CELL CYTOPLASMIC AUTOANTIBODY; UNCLASSIFIED DRUG;

EID: 84863983828     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-012-9673-4     Document Type: Article
Times cited : (10)

References (51)
  • 1
    • 0022617990 scopus 로고
    • Diabetes: A chronic autoimmune disease
    • Eisenbarth GS. Diabetes: A chronic autoimmune disease. N Engl J Med. 1986;314:1360-8.
    • (1986) N Engl J Med , vol.314 , pp. 1360-1368
    • Eisenbarth, G.S.1
  • 2
    • 0028779842 scopus 로고
    • The pathogenesis of insulindependent diabetes mellitus
    • Atkinson MA, Maclaren NK. The pathogenesis of insulindependent diabetes mellitus. N Engl J Med. 1994;331:1428-36.
    • (1994) N Engl J Med , vol.331 , pp. 1428-1436
    • Atkinson, M.A.1    Maclaren, N.K.2
  • 3
    • 33746207753 scopus 로고    scopus 로고
    • Type 1 pathogenesis and prevention
    • Gillespie KM. Type 1 pathogenesis and prevention. CMAJ. 2006;175:165-70.
    • (2006) CMAJ , vol.175 , pp. 165-170
    • Gillespie, K.M.1
  • 5
    • 0019226693 scopus 로고
    • Gene dosage and susceptibility to insulin-dependent diabetes
    • Spielman RS, Baker L, Zmijewski CM. Gene dosage and susceptibility to insulin-dependent diabetes. Ann Hum Genet. 1980;2:135-50. (Pubitemid 11215106)
    • (1980) Annals of Human Genetics , vol.44 , Issue.2 , pp. 135-150
    • Spielman, R.S.1    Baker, L.2    Zmijewski, C.M.3
  • 6
    • 0027169651 scopus 로고
    • North-American twins with IDDM: Genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin
    • Kumar D, Gemayel NS, Deapen D, Kapadia D, Yamashita PH, Lee M, Dwyer JH, Roy-Burman P, Bray GA, Mack TM. North- American twins with IDDM, genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin. Diabetes. 1993;42:1351-63. (Pubitemid 23259856)
    • (1993) Diabetes , vol.42 , Issue.9 , pp. 1351-1363
    • Kumar, D.1    Gemayel, N.S.2    Deapen, D.3    Kapadia, D.4    Yamashita, P.H.5    Lee, M.6    Dwyer, J.H.7    Roy-Burman, P.8    Bray, G.A.9    Mack, T.M.10
  • 7
    • 0026500805 scopus 로고
    • Prospective in diabetes. HLA and insulin-dependent diabetes. A protective perspective
    • Sheehly MJ. Prospective in diabetes. HLA and insulin-dependent diabetes. A protective perspective. Diabetes. 1992;41:123-9.
    • (1992) Diabetes , vol.41 , pp. 123-129
    • Sheehly, M.J.1
  • 9
    • 0023252262 scopus 로고
    • HLA-DQ(β) gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
    • DOI 10.1038/329599a0
    • Todd JA, Bell JJ, McDevitt HO. HLA-DQ/ß gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature. 1987;329:599-604. (Pubitemid 17140111)
    • (1987) Nature , vol.329 , Issue.6140 , pp. 599-604
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 11
    • 79951796881 scopus 로고    scopus 로고
    • Prediction and prevention of Type 1 diabetes mellitus
    • Zhang L, Eisenbarth GS. Prediction and prevention of Type 1 diabetes mellitus. J Diabetes. 2011;3:48-57.
    • (2011) J Diabetes , vol.3 , pp. 48-57
    • Zhang, L.1    Eisenbarth, G.S.2
  • 12
    • 0025141413 scopus 로고
    • Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes
    • DOI 10.1016/0140-6736(90)90013-U
    • Bonifacio E, Bingley PJ, Shattock M, Dean BM, Dunger D, Gale EA, Bottazzo GF. Quantification of islet-cell antibodies and prediction of insulin dependent diabetes. Lancet. 1990;335:147-9. (Pubitemid 20032735)
    • (1990) Lancet , vol.335 , Issue.8682 , pp. 147-149
    • Bonifacio, E.1    Bingley, P.J.2    Shattock, M.3    Dean, B.M.4    Dunger, D.5    Gale, E.A.M.6    Bottazzo, G.F.7
  • 13
    • 0032961804 scopus 로고    scopus 로고
    • Relationship of β-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: Follow-up of the Seattle Family Study
    • DOI 10.2337/diabetes.48.1.170
    • Greenbaum CJ, Seras KL, Kahn SE, Palmer JP. Relationship of bcells function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes. Diabetes. 1999;48:170-5. (Pubitemid 29019369)
    • (1999) Diabetes , vol.48 , Issue.1 , pp. 170-175
    • Greenbaum, C.J.1    Sears, K.L.2    Kahn, S.E.3    Palmer, J.P.4
  • 16
    • 0016261369 scopus 로고
    • Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies
    • Bottazo GF, Florin-Christensen A, Doniach D. Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet. 1974;2:1279-82.
    • (1974) Lancet , vol.2 , pp. 1279-1282
    • Bottazo, G.F.1    Florin-Christensen, A.2    Doniach, D.3
  • 18
    • 84873501673 scopus 로고
    • Identification of the 64 K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decorboxylase [published erratum appears in
    • Baekkeskov S, Aanstoot H-J, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F, Richter-Olesen H, De Camilli P. et al. Identification of the 64 K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decorboxylase [published erratum appears in (1990) Nature. 1990;347:782]. Nature. 1990; 347151-156.
    • (1990) Nature , vol.782 , pp. 347151-347156
    • Baekkeskov, S.1    Aanstoot, H.-J.2    Christgau, S.3    Reetz, A.4    Solimena, M.5    Cascalho, M.6    Folli, F.7    Richter-Olesen, H.8    De Camilli, P.9
  • 19
    • 0029120042 scopus 로고
    • Relationship of 37,000 and 40,000-Mr tryptic fragment of islet antigens in insulin dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA 512)
    • Payton MA, Hawkes CJ, Christie MR. Relationship of 37,000 and 40,000-Mr tryptic fragment of islet antigens in insulin dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA 512). J Clin Invest. 1995;96:1506-11.
    • (1995) J Clin Invest , vol.96 , pp. 1506-1511
    • Payton, M.A.1    Hawkes, C.J.2    Christie, M.R.3
  • 20
    • 0021019885 scopus 로고
    • Insulin antibodies in insulin-dependent diabetics before insulin treatment
    • Palmer JP, Asplin CM, Clemons P, Lyen K, Tatpati O, Raghu PK, Paquette TL. Insulin antibodies in insulin-dependent diabetics before insulin treatment. Science. 1983;222:1337-9. (Pubitemid 14204704)
    • (1983) Science , vol.222 , Issue.4630 , pp. 1337-1339
    • Palmer, J.P.1    Asplin, C.M.2    Clemons, P.3
  • 21
    • 33644750399 scopus 로고    scopus 로고
    • Autoantibodies in diabetes
    • DOI 10.2337/diabetes.54.suppl-2.S52
    • Pihoker C, Gilliam LK, Hampe CS, Lenmark A. Autoantibodies in diabetes. Diabetes. 2005;54 Suppl 2:S52-61. (Pubitemid 43343331)
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 2
    • Pihoker, C.1    Gilliam, L.K.2    Hampe, C.S.3    Lernmark, A.4
  • 25
    • 48149094190 scopus 로고    scopus 로고
    • Autoantibodies to islet antigen-2 are associated with KLA-DRBI 07, and DRBI 09 haplotypes as well as DRBI 04 at onset of type 1 diabetes: The possible role of HLA-DQA in autoimmunity to IA-2
    • Williams AJ, Aitken RJ, Chandler MA, Gillespie KM, Lampsona V, Bingley PJ. Autoantibodies to islet antigen-2 are associated with KLA-DRBI 07, and DRBI 09 haplotypes as well as DRBI 04 at onset of type 1 diabetes: The possible role of HLA-DQA in autoimmunity to IA-2. Diabetologia. 2008;51:1444-8.
    • (2008) Diabetologia , vol.51 , pp. 1444-1448
    • Williams, A.J.1    Aitken, R.J.2    Chandler, M.A.3    Gillespie, K.M.4    Lampsona, V.5    Bingley, P.J.6
  • 26
    • 67650501545 scopus 로고    scopus 로고
    • The effect of the MHC locus on autoantibodies in type 1 diabetes
    • Qu HQ, Polychronakos C. The effect of the MHC locus on autoantibodies in type 1 diabetes. J Med Genet. 2009;46:469-71.
    • (2009) J Med Genet , vol.46 , pp. 469-471
    • Qu, H.Q.1    Polychronakos, C.2
  • 27
    • 80053416976 scopus 로고    scopus 로고
    • Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to 1A-2 are distinct
    • Howson JM, Stevens H, Smyth DJ, et al. Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to 1A-2 are distinct. Diabetes. 2011;60:2635-44.
    • (2011) Diabetes , vol.60 , pp. 2635-2644
    • Howson, J.M.1    Stevens, H.2    Smyth, D.J.3
  • 28
    • 78751662679 scopus 로고    scopus 로고
    • Type 1 diabetes: Etiology, immunology, and therapeutic strategies
    • van Belle TL, Coppieters KT, von Herrath MG. Type 1 diabetes: Etiology, immunology, and therapeutic strategies. Physiol Rev. 2011;91:79-118.
    • (2011) Physiol Rev , vol.91 , pp. 79-118
    • Van Belle, T.L.1    Coppieters, K.T.2    Von Herrath, M.G.3
  • 29
    • 77249160660 scopus 로고    scopus 로고
    • Genetic composition of Brazilian population samples based on a set of twenty-eight ancestry informative SNPs
    • Lins TC, Vieira RG, Abreu BS, Grattapaglia D, Pereira RW. Genetic composition of Brazilian population samples based on a set of twenty-eight ancestry informative SNPs. Am J Hum Biol. 2010;22:187-92.
    • (2010) Am J Hum Biol , vol.22 , pp. 187-192
    • Lins, T.C.1    Vieira, R.G.2    Abreu, B.S.3    Grattapaglia, D.4    Pereira, R.W.5
  • 31
    • 2342466734 scopus 로고    scopus 로고
    • Diabetes Care. 2004;27:1047-53.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
  • 35
    • 84873496304 scopus 로고    scopus 로고
    • Ogenótipo I/I do locus VNTR do gene da insulina confere risco independente para diabetes mellitus tipo 1 nos pacientes sem os genótipos DRB1 e DQB1 de susceptibilidade
    • Davini E, Silva MER, Alves LI, Correia MRS, Fukui RT, Latronico AC. O genótipo I/I do locus VNTR do gene da insulina confere risco independente para diabetes mellitus tipo 1 nos pacientes sem os genótipos DRB1 e DQB1 de susceptibilidade. Arq Bras Endocrinol Metab. 2005;49 Suppl 2:S876.
    • (2005) Arq Bras Endocrinol Metab , vol.49 , Issue.SUPPL. 2
    • Davini, E.1    Silva, M.E.R.2    Alves, L.I.3    Correia, M.R.S.4    Fukui, R.T.5    Latronico, A.C.6
  • 37
    • 40349084011 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes
    • American Diabetes Association
    • American Diabetes Association. Diagnosis and classification of diabetes. Diabetes Care. 2008;31 Suppl 1:S55-60.
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 1
  • 38
    • 0023722804 scopus 로고    scopus 로고
    • Concentration of insulin autoantibodies at onset of type 1 diabetes. Inverse log-linear correlation with age
    • Vardi P, Ziegler AG, Mattews JH, Dib S, Keller RJ, Richer AT. Concentration of insulin autoantibodies at onset of type 1 diabetes. Inverse log-linear correlation with age. Diabetes Care. 1998;11:736-9.
    • (1998) Diabetes Care , vol.11 , pp. 736-739
    • Vardi, P.1    Ziegler, A.G.2    Mattews, J.H.3    Dib, S.4    Keller, R.J.5    Richer, A.T.6
  • 39
    • 0023240614 scopus 로고
    • Expression of cytoplasmic islet cell antigens by rat pancreas
    • Dib SA, Colman PG, Dotta F, Tautkus M, Rabizadeh A, Eisenbarth GS. Expression of cytoplasmic islet cell antigens by rat pancreas. Diabetes. 1987;36:982-5. (Pubitemid 17136812)
    • (1987) Diabetes , vol.36 , Issue.8 , pp. 982-985
    • Dib, S.A.1    Colman, P.G.2    Dotta, F.3
  • 40
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 42
    • 33845709151 scopus 로고    scopus 로고
    • Why is type 1 diabetes uncommon in Asia?
    • Park Y. Why is type 1 diabetes uncommon in Asia? Ann NYAcad Sci. 2006;1079:31-40.
    • Ann NYAcad Sci , vol.2006 , Issue.1079 , pp. 31-40
    • Park, Y.1
  • 43
    • 0020385959 scopus 로고
    • Pancreatic islet cell and thyroid antibodies, and islet cell function in diabetic patients of Mexican-American origin
    • Zeidler A, Frasier SD, Penny R, Stein RB, Nicoloff JT. Pancreatic islet cell and thyroid antibodies, and islet cell function in diabetic patients of Mexican-American origin. J Clin Endocrinol Metab. 1982;54:949-54. (Pubitemid 13243702)
    • (1982) Journal of Clinical Endocrinology and Metabolism , vol.54 , Issue.5 , pp. 949-954
    • Zeidler, A.1    Frasier, S.D.2    Penny, R.3
  • 45
    • 33646052603 scopus 로고    scopus 로고
    • Clinical review: Type 1 diabetes-associated autoimmunity: Natural history, genetic associations, and screening
    • Baker JM. Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening. J Clin Endocrinol Metab. 2006;91:1210-7.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1210-1217
    • Baker, J.M.1
  • 47
    • 0029995958 scopus 로고    scopus 로고
    • Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
    • Verge CF, Gianani R, Kawasaki E, Yu L, Pietropolo M, Jackson RA, Chase HP, Eisenbarth GS. Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, ICA512bdc/IA-2 autoantibodies. Diabetes. 1996;45:926-33. (Pubitemid 26225509)
    • (1996) Diabetes , vol.45 , Issue.3 SUPPL. , pp. 926-933
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3    Yu, L.4    Pietropaolo, M.5    Jackson, R.A.6    Chase, H.P.7    Eisenbarth, G.S.8
  • 48
    • 0028793704 scopus 로고
    • WJ, Malone J, Schwartz S, Quattrin T, Maclaren NK. Age and family relationship accentuate the risk of insulin-dependent diabetes mellitus (IDDM) in relatives of patients with IDDM
    • Riley
    • Cantor AB, Krischer JP, Cuthbertson DD, Schatz DA, Riley WJ, Malone J, Schwartz S, Quattrin T, Maclaren NK. Age and family relationship accentuate the risk of insulin-dependent diabetes mellitus (IDDM) in relatives of patients with IDDM. J Clin Endocrinol Metab. 1995;80:3739-43.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3739-3743
    • Cantor, A.B.1    Krischer, J.P.2    Cuthbertson, D.D.3    Schatz, D.A.4
  • 49
    • 0028911293 scopus 로고
    • High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years. The Belgian Diabetes Registry
    • Vandewalle CL, Falorni A, Svanholm S, Lernmark A, Pipeleers DG, Gorus FK. High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years. The Belgian Diabetes Registry. J Clin Endocrinol Metab. 1995;80:846-51.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 846-851
    • Vandewalle, C.L.1    Falorni, A.2    Svanholm, S.3    Lernmark, A.4    Pipeleers, D.G.5    Gorus, F.K.6
  • 50
    • 0028989040 scopus 로고
    • HLA-DQB1 0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM
    • Pugliese A, Gianani R, Moromissato R, Awdeh ZL, Alper CA, Erlich HA, Jackson RA, Eisenbath GS. HLA-DQB1 0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM. Diabetes. 1995;44:608-13.
    • (1995) Diabetes , vol.44 , pp. 608-613
    • Pugliese, A.1    Gianani, R.2    Moromissato, R.3    Awdeh, Z.L.4    Alper, C.A.5    Erlich, H.A.6    Jackson, R.A.7    Eisenbath, G.S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.