The potential role of anibamine, a natural product CCR5 antagonist, and its analogues as leads toward development of anti-ovarian cancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 15, 2012, Pages 5093-5097

  Zhang, Yan ^a,b   Arnatt, Christopher K ^a   Zhang, Feng ^a   Wang, Jiannan ^a   Haney, Kendra M ^a   Fang, Xianjun ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Anibamine; CCR5; Chemokines; Ovarian cancer

Indexed keywords

ANIBAMINE; ANIBAMINE DERIVATIVE; ANTINEOPLASTIC AGENT; CALCIUM ION; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CALCIUM TRANSPORT; CANCER CELL CULTURE; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; OVARY CANCER; STRUCTURE ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CALCIUM; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HUMANS; LIGANDS; MICE; NIH 3T3 CELLS; OVARIAN NEOPLASMS; PYRIDINES; RECEPTORS, CCR5; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84863983070     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.05.127     Document Type: Article

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