Mutagenicity of 5-Hydroxymethylfurfural in V79 cells expressing human SULT1A1: Identification and mass spectrometric quantification of DNA adducts formed

Chemical Research in Toxicology

Volumn 25, Issue 7, 2012, Pages 1484-1492

  Monien, Bernhard H ^a   Engst, Wolfram ^a   Barknowitz, Gitte ^a   Seidel, Albrecht ^b   Glatt, Hansruedi ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b Prof Dr Gernot Grimmer Foundation   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLFURFURAL; 5 METHYLFURFURYL; 5 SULFOOXYMETHYLFURFURAL; CARBON; DEOXYADENOSINE; FURAN DERIVATIVE; IMINE; N2 [(2 FORMYLFURAN 5 YL) METHYL] 2' DEOXYGUANOSINE; N6 [(2 FORMYLFURAN 5 YL) METHYL] 2' DEOXYADENOSINE; NUCLEOSIDE; SULFOTRANSFERASE 1A1; UNCLASSIFIED DRUG;

ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA ADDUCT; ELECTROPHILICITY; GENE MUTATION; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUTAGENICITY; NONHUMAN; NUCLEOPHILICITY; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; TANDEM MASS SPECTROMETRY;

ANIMALS; ARYLSULFOTRANSFERASE; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; DNA; DNA ADDUCTS; FEMALE; FURALDEHYDE; HUMANS; ISOTOPE LABELING; MICE; MUTAGENICITY TESTS; TANDEM MASS SPECTROMETRY;

CRICETULUS GRISEUS; MUS;

EID: 84863952057     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx300150n     Document Type: Article

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