메뉴 건너뛰기




Volumn , Issue , 2006, Pages 328-357

Health risks of 5-hydroxymethylfurfural (HMF) and related compounds

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84903654575     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-1-84569-011-3.50015-X     Document Type: Chapter
Times cited : (90)

References (81)
  • 4
    • 0025707819 scopus 로고
    • Mechanism of formation of 5-(hydroxymethyl)-2-furaldehyde from D-fructose and sucrose
    • Antal MJ Jr, Mok W.S., Richards G.N. Mechanism of formation of 5-(hydroxymethyl)-2-furaldehyde from D-fructose and sucrose. Carbohydr Res 1990, 199:91-109.
    • (1990) Carbohydr Res , vol.199 , pp. 91-109
    • Antal Jr., M.J.1    Mok, W.S.2    Richards, G.N.3
  • 5
    • 3042518890 scopus 로고    scopus 로고
    • Subacute (28-day) toxicity of furfural in Fischer 344 rats: a comparison of the oral and inhalation route
    • Arts J.H., Muijser H., Appel M.J., Frieke Kuper C., Bessems J.G., Woutersen R.A. Subacute (28-day) toxicity of furfural in Fischer 344 rats: a comparison of the oral and inhalation route. Food Chem Toxicol 2004, 42:1389-1399.
    • (2004) Food Chem Toxicol , vol.42 , pp. 1389-1399
    • Arts, J.H.1    Muijser, H.2    Appel, M.J.3    Frieke Kuper, C.4    Bessems, J.G.5    Woutersen, R.A.6
  • 6
    • 0343974204 scopus 로고    scopus 로고
    • 5-Hydroxymethyl-2-furfural (HMF) in Lebensmitteln
    • Bachmann S., Meier M., Känzig A. 5-Hydroxymethyl-2-furfural (HMF) in Lebensmitteln. Lebensmittelchemie 1997, 51:49-50.
    • (1997) Lebensmittelchemie , vol.51 , pp. 49-50
    • Bachmann, S.1    Meier, M.2    Känzig, A.3
  • 7
    • 33646348993 scopus 로고    scopus 로고
    • Uptake of chemically reactive, DNA-damaging sulfuric acid esters into renal cells by human organic anion transporters
    • Bakhiya N., Stephani M., Seidel A., Bahn A., Ugele B., Burckhardt G., Glatt H.R. Uptake of chemically reactive, DNA-damaging sulfuric acid esters into renal cells by human organic anion transporters. J Am Soc Nephrol 2006, 17:1414-1421.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1414-1421
    • Bakhiya, N.1    Stephani, M.2    Seidel, A.3    Bahn, A.4    Ugele, B.5    Burckhardt, G.6    Glatt, H.R.7
  • 8
    • 0023952459 scopus 로고
    • Sulfation of benzylic alcohols catalyzed by aryl sulfotransferase IV
    • Binder T.P., Duffel M.W. Sulfation of benzylic alcohols catalyzed by aryl sulfotransferase IV. Mol Pharmacol 1988, 33:477-479.
    • (1988) Mol Pharmacol , vol.33 , pp. 477-479
    • Binder, T.P.1    Duffel, M.W.2
  • 9
    • 0014007585 scopus 로고
    • Isolation of 5-hydroxymethylfurfural from cigarette smoke condensate
    • Black D.K. Isolation of 5-hydroxymethylfurfural from cigarette smoke condensate. Chem Ind 1966, 32:1380.
    • (1966) Chem Ind , vol.32 , pp. 1380
    • Black, D.K.1
  • 11
    • 10844243981 scopus 로고    scopus 로고
    • 6-etheno-2'-deoxyguanosine adducts by cis-2-butene-1,4-dial, a reactive metabolite of furan'
    • 6-etheno-2'-deoxyguanosine adducts by cis-2-butene-1,4-dial, a reactive metabolite of furan'. Chem Res Toxicol 2004, 17:1607-1613.
    • (2004) Chem Res Toxicol , vol.17 , pp. 1607-1613
    • Byrns, M.C.1    Vu, C.C.2    Peterson, L.A.3
  • 12
    • 0028785113 scopus 로고
    • Identification of cis-2-butene-1,4-dial as a microsomal metabolite of furan
    • Chen L.J., Hecht S.S., Peterson L.A. Identification of cis-2-butene-1,4-dial as a microsomal metabolite of furan. Chem Res Toxicol 1995, 8:903-906.
    • (1995) Chem Res Toxicol , vol.8 , pp. 903-906
    • Chen, L.J.1    Hecht, S.S.2    Peterson, L.A.3
  • 13
    • 0025049001 scopus 로고
    • Promotion of colonic microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat
    • Corpet D.E., Stamp D., Medline A., Minkin S., Archer M.C., Bruce W.R. promotion of colonic microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat. Cancer Res 1990, 50:6955-6958.
    • (1990) Cancer Res , vol.50 , pp. 6955-6958
    • Corpet, D.E.1    Stamp, D.2    Medline, A.3    Minkin, S.4    Archer, M.C.5    Bruce, W.R.6
  • 14
    • 0024438049 scopus 로고
    • Sources and concentrations of aldehydes and ketones in indoor environments in the UK
    • Crump D.R., Gardner D. Sources and concentrations of aldehydes and ketones in indoor environments in the UK. Environ Int 1989, 15:455-462.
    • (1989) Environ Int , vol.15 , pp. 455-462
    • Crump, D.R.1    Gardner, D.2
  • 15
    • 0014911117 scopus 로고
    • [Tolerance of 5-hydroxymethylfurfural (HMF). 2d communication: pharmacologic effects]
    • Czok G. [Tolerance of 5-hydroxymethylfurfural (HMF). 2d communication: pharmacologic effects]. Z Ernährungswiss 1970, 10:103-110.
    • (1970) Z Ernährungswiss , vol.10 , pp. 103-110
    • Czok, G.1
  • 17
    • 0018345866 scopus 로고
    • Respiratory retention and acute toxicity of furan
    • Egle J.L., Gochberg B.J. Respiratory retention and acute toxicity of furan. Am Ind Hyg Assoc J 1979, 40:310-314.
    • (1979) Am Ind Hyg Assoc J , vol.40 , pp. 310-314
    • Egle, J.L.1    Gochberg, B.J.2
  • 18
    • 0025934727 scopus 로고
    • Phenotypic characterization of metaplastic intestinal glands and ductular hepatocytes in cholangiofibrotic lesions rapidly induced in the caudate liver lobe of rats treated with furan
    • Elmore L.W., Sirica A.E. Phenotypic characterization of metaplastic intestinal glands and ductular hepatocytes in cholangiofibrotic lesions rapidly induced in the caudate liver lobe of rats treated with furan. Cancer Res 1991, 51:5752-5759.
    • (1991) Cancer Res , vol.51 , pp. 5752-5759
    • Elmore, L.W.1    Sirica, A.E.2
  • 19
    • 0015252466 scopus 로고
    • Respiratory tract tumors in hamsters after intratracheal instillations of benzo[a]pyrene alone and with furfural
    • Feron V.J. Respiratory tract tumors in hamsters after intratracheal instillations of benzo[a]pyrene alone and with furfural. Cancer Res 1972, 32:28-36.
    • (1972) Cancer Res , vol.32 , pp. 28-36
    • Feron, V.J.1
  • 20
    • 0018085154 scopus 로고
    • Effects of exposure to furfural vapour in hamsters simultaneously treated with benzo[a]pyrene or diethylnitrosamine
    • Feron V.J., Kruysse A. Effects of exposure to furfural vapour in hamsters simultaneously treated with benzo[a]pyrene or diethylnitrosamine. Toxicology 1978, 11:127-144.
    • (1978) Toxicology , vol.11 , pp. 127-144
    • Feron, V.J.1    Kruysse, A.2
  • 21
    • 0017339161 scopus 로고
    • Availability of the true Schiff's bases of lysine: chemical evaluation of Schiff's bases between lysine and lactose in milk
    • Plenum Publ. Corp, New York, M. Friedman (Ed.)
    • Finot P.A., Bujard E., Mottu F., Mauron J. Availability of the true Schiff's bases of lysine: chemical evaluation of Schiff's bases between lysine and lactose in milk. Protein Cross-linking 1977, 343-365. Plenum Publ. Corp, New York. M. Friedman (Ed.).
    • (1977) Protein Cross-linking , pp. 343-365
    • Finot, P.A.1    Bujard, E.2    Mottu, F.3    Mauron, J.4
  • 22
    • 0018187525 scopus 로고
    • The absorption, metabolism and excretion of furfural in man
    • Flek J., Sedivec V. The absorption, metabolism and excretion of furfural in man. Int Arch Occup Environ Health 1978, 41:159-168.
    • (1978) Int Arch Occup Environ Health , vol.41 , pp. 159-168
    • Flek, J.1    Sedivec, V.2
  • 23
    • 0018822306 scopus 로고
    • Screening of tobacco smoke constituents for mutagenicity using the Ames test'
    • Florin I., Rutberg L., Curvall M., Enzell C.R. Screening of tobacco smoke constituents for mutagenicity using the Ames test'. Toxicology 1980, 15:219-232.
    • (1980) Toxicology , vol.15 , pp. 219-232
    • Florin, I.1    Rutberg, L.2    Curvall, M.3    Enzell, C.R.4
  • 25
    • 84903651941 scopus 로고    scopus 로고
    • Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants
    • The National Academies Press, Washington, C.O.L. Sciences (Ed.)
    • Garcia H.D., James J.T. Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants. Furan 2000, Volume 4. The National Academies Press, Washington. C.O.L. Sciences (Ed.).
    • (2000) Furan , vol.4
    • Garcia, H.D.1    James, J.T.2
  • 26
    • 0001571534 scopus 로고
    • Liquid chromatography for the determination of 5-(hydroxymethyl)-2-furaldehyde in breakfast cereals
    • García-Villanova B., Guerra-Hernández E., Martínez-Gómez E., Montilla J. Liquid chromatography for the determination of 5-(hydroxymethyl)-2-furaldehyde in breakfast cereals. J Agr Food Chem 1993, 41:1254-1255.
    • (1993) J Agr Food Chem , vol.41 , pp. 1254-1255
    • García-Villanova, B.1    Guerra-Hernández, E.2    Martínez-Gómez, E.3    Montilla, J.4
  • 28
    • 0034534841 scopus 로고    scopus 로고
    • Sulfotransferases in the bioactivation of xenobiotics
    • Glatt H.R. Sulfotransferases in the bioactivation of xenobiotics. Chem-Biol Interact 2000, 129:141-170.
    • (2000) Chem-Biol Interact , vol.129 , pp. 141-170
    • Glatt, H.R.1
  • 29
    • 30144435525 scopus 로고    scopus 로고
    • Activation and inactivation of carcinogens by human sulfotransferases
    • Taylor & Francis, London, G.M. Pacifici, M.W.H. Coughtrie (Eds.)
    • Glatt H.R. Activation and inactivation of carcinogens by human sulfotransferases. Human Sulphotransferases 2005, 281-306. Taylor & Francis, London. G.M. Pacifici, M.W.H. Coughtrie (Eds.).
    • (2005) Human Sulphotransferases , pp. 281-306
    • Glatt, H.R.1
  • 30
    • 30144438098 scopus 로고    scopus 로고
    • Sulfotransferases and acetyltransferases in mutagenicity testing: technical aspects
    • Glatt H.R., Meinl W. Sulfotransferases and acetyltransferases in mutagenicity testing: technical aspects. Meth Enzymol 2005, 400:230-249.
    • (2005) Meth Enzymol , vol.400 , pp. 230-249
    • Glatt, H.R.1    Meinl, W.2
  • 33
    • 31844441500 scopus 로고    scopus 로고
    • Metabolic formation, distribution and toxicological effects of reactive sulphuric acid esters
    • Glatt H.R., Meinl W., Kuhlow A., Ma L. Metabolic formation, distribution and toxicological effects of reactive sulphuric acid esters. Nova Acta Leopoldina NF87 2003, 329:151-161.
    • (2003) Nova Acta Leopoldina NF87 , vol.329 , pp. 151-161
    • Glatt, H.R.1    Meinl, W.2    Kuhlow, A.3    Ma, L.4
  • 34
    • 12744258127 scopus 로고    scopus 로고
    • V79-hCYP2E1-hSULT1A1, a cell line for the sensitive detection of genotoxic effects induced by carbohydrate pyrolysis products and other food-borne chemicals
    • Glatt H.R., Schneider H., Liu Y.-G. V79-hCYP2E1-hSULT1A1, a cell line for the sensitive detection of genotoxic effects induced by carbohydrate pyrolysis products and other food-borne chemicals. Mutation Res 2005, 580:41-52.
    • (2005) Mutation Res , vol.580 , pp. 41-52
    • Glatt, H.R.1    Schneider, H.2    Liu, Y.-G.3
  • 37
    • 0342828255 scopus 로고
    • Determinacion espectrofotometrica y cromatografica de hidroximetil-furfural en vino: estudio comparativo
    • Guerra-Hernández E.J., Montilla-Gómez J., García-Villanova B. Determinacion espectrofotometrica y cromatografica de hidroximetil-furfural en vino: estudio comparativo. Quim Anal 1988, 7:100-106.
    • (1988) Quim Anal , vol.7 , pp. 100-106
    • Guerra-Hernández, E.J.1    Montilla-Gómez, J.2    García-Villanova, B.3
  • 38
    • 0029927245 scopus 로고    scopus 로고
    • Quantitation of 5-hydroxymethylfurfural (5-HMF) and related substances in dextrose injections containing drugs and bisulfite
    • Hryncewicz C.L., Koberda M., Konkowski M.S. Quantitation of 5-hydroxymethylfurfural (5-HMF) and related substances in dextrose injections containing drugs and bisulfite. J Pharm Biomed Analys 1996, 14:429-434.
    • (1996) J Pharm Biomed Analys , vol.14 , pp. 429-434
    • Hryncewicz, C.L.1    Koberda, M.2    Konkowski, M.S.3
  • 39
    • 0033889614 scopus 로고    scopus 로고
    • 5-Hydroxymethylfurfural: assessment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione
    • Janzowski C., Glaab V., Samimi E., Schlatter J., Eisenbrand G. 5-Hydroxymethylfurfural: assessment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione. Food Chem Toxicol 2000, 38:801-809.
    • (2000) Food Chem Toxicol , vol.38 , pp. 801-809
    • Janzowski, C.1    Glaab, V.2    Samimi, E.3    Schlatter, J.4    Eisenbrand, G.5
  • 40
    • 0015862157 scopus 로고
    • The presence of furan derivatives in patients receiving fructose-containing solutions intravenously
    • Jellum E., Borresen H.C., Eldjarn L. The presence of furan derivatives in patients receiving fructose-containing solutions intravenously. Clin Chim Acta 1973, 47:191-201.
    • (1973) Clin Chim Acta , vol.47 , pp. 191-201
    • Jellum, E.1    Borresen, H.C.2    Eldjarn, L.3
  • 42
    • 0030246901 scopus 로고    scopus 로고
    • Prediction of furan pharmacokinetics from hepatocyte studies: comparison of bioactivation and hepatic dosimetry in rats, mice, and humans
    • Kedderis G.L., Held S.D. Prediction of furan pharmacokinetics from hepatocyte studies: comparison of bioactivation and hepatic dosimetry in rats, mice, and humans. Toxicol Appl Pharmacol 1996, 140:124-130.
    • (1996) Toxicol Appl Pharmacol , vol.140 , pp. 124-130
    • Kedderis, G.L.1    Held, S.D.2
  • 43
    • 0034885573 scopus 로고    scopus 로고
    • Lack of effect of furfural on unscheduled DNA synthesis in the in vivo rat and mouse hepatocyte DNA repair assays and in precision-cut human liver slices
    • Lake B.G., Edwards A.J., Price R.J., Phillips B.J., Renwick A.B., Beamand J.A., Adams T.B. Lack of effect of furfural on unscheduled DNA synthesis in the in vivo rat and mouse hepatocyte DNA repair assays and in precision-cut human liver slices. Food Chem Toxicol 2001, 39:999-1011.
    • (2001) Food Chem Toxicol , vol.39 , pp. 999-1011
    • Lake, B.G.1    Edwards, A.J.2    Price, R.J.3    Phillips, B.J.4    Renwick, A.B.5    Beamand, J.A.6    Adams, T.B.7
  • 44
    • 0030355238 scopus 로고    scopus 로고
    • Benzylic sulphuric acid esters react with diverse functional groups and often form secondary reactive species
    • Landsiedel R., Engst W., Scholtyssek M., Seidel A., Glatt H.R. Benzylic sulphuric acid esters react with diverse functional groups and often form secondary reactive species. Polycyclic Aromat Compds 1996, 11:341-348.
    • (1996) Polycyclic Aromat Compds , vol.11 , pp. 341-348
    • Landsiedel, R.1    Engst, W.2    Scholtyssek, M.3    Seidel, A.4    Glatt, H.R.5
  • 45
    • 0014911585 scopus 로고
    • [Tolerance of 5-hydroxymethylfurfural (HMF). 1st communication: chronic administration of HMF and metabolites of the substance]
    • Lang K., Kieckebusch W., Bassler K.H., Griem W., Czok G. [Tolerance of 5-hydroxymethylfurfural (HMF). 1st communication: chronic administration of HMF and metabolites of the substance]. Z Ernährungswiss 1970, 10:97-101.
    • (1970) Z Ernährungswiss , vol.10 , pp. 97-101
    • Lang, K.1    Kieckebusch, W.2    Bassler, K.H.3    Griem, W.4    Czok, G.5
  • 46
    • 0029049978 scopus 로고
    • Bioactivation of 5-hydroxymethyl-2-furaldehyde to an electrophilic and mutagenic allylic sulfuric acid ester
    • Lee Y.C., Shlyankevich M., Jeong H.K., Douglas J.S., Surh Y.J. Bioactivation of 5-hydroxymethyl-2-furaldehyde to an electrophilic and mutagenic allylic sulfuric acid ester. Biochem Biophys Res Commun 1995, 209:996-1002.
    • (1995) Biochem Biophys Res Commun , vol.209 , pp. 996-1002
    • Lee, Y.C.1    Shlyankevich, M.2    Jeong, H.K.3    Douglas, J.S.4    Surh, Y.J.5
  • 47
    • 0030598389 scopus 로고    scopus 로고
    • Sulfotransferase gene expression in primary cultures of rat hepatocytes
    • Liu L., Lecluyse E.L., Liu J., Klaassen C.D. Sulfotransferase gene expression in primary cultures of rat hepatocytes. Biochem Pharmacol 1996, 52:1621-1630.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1621-1630
    • Liu, L.1    Lecluyse, E.L.2    Liu, J.3    Klaassen, C.D.4
  • 48
    • 0021203649 scopus 로고
    • The effects of diethyldithiocarbamate and carbon disulfide on acute nephrotoxicity induced by furan, bromobenzene and cephaloridine in mice
    • Masuda Y., Nakayama N., Yamaguchi A., Murohashi M. The effects of diethyldithiocarbamate and carbon disulfide on acute nephrotoxicity induced by furan, bromobenzene and cephaloridine in mice. Jpn J Pharmacol 1984, 34:221-229.
    • (1984) Jpn J Pharmacol , vol.34 , pp. 221-229
    • Masuda, Y.1    Nakayama, N.2    Yamaguchi, A.3    Murohashi, M.4
  • 49
    • 0019762671 scopus 로고
    • The Maillard reaction in food; a critical review from the nutritional standpoint
    • Mauron J. The Maillard reaction in food; a critical review from the nutritional standpoint. Prog Food Nutr Sci 1981, 5:5-35.
    • (1981) Prog Food Nutr Sci , vol.5 , pp. 5-35
    • Mauron, J.1
  • 50
    • 0017751555 scopus 로고
    • Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine
    • Mcmurtry R.J., Mitchell J.R. Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine. Toxicol Appl Pharmacol 1977, 42:285-300.
    • (1977) Toxicol Appl Pharmacol , vol.42 , pp. 285-300
    • Mcmurtry, R.J.1    Mitchell, J.R.2
  • 51
    • 31844448260 scopus 로고    scopus 로고
    • Human sulfotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue
    • Meinl W., Pabel U., Osterloh-Quiroz M., Hengstler J.G., Glatt H.R. Human sulfotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue. Int J Cancer 2006, 118:1090-1097.
    • (2006) Int J Cancer , vol.118 , pp. 1090-1097
    • Meinl, W.1    Pabel, U.2    Osterloh-Quiroz, M.3    Hengstler, J.G.4    Glatt, H.R.5
  • 52
    • 0025784793 scopus 로고
    • Initiating activity of eight pyrolysates of carbohydrates in a two-stage mouse skin tumorigenesis model
    • Miyakawa Y., Nishi Y., Kato K., Sato H., Takahashi M., Hayashi Y. Initiating activity of eight pyrolysates of carbohydrates in a two-stage mouse skin tumorigenesis model. Carcinogenesis 1991, 12:1169-1173.
    • (1991) Carcinogenesis , vol.12 , pp. 1169-1173
    • Miyakawa, Y.1    Nishi, Y.2    Kato, K.3    Sato, H.4    Takahashi, M.5    Hayashi, Y.6
  • 53
    • 0031148804 scopus 로고    scopus 로고
    • Furan-mediated uncoupling of hepatic oxidative phosphorylation in Fischer-344 rats: an early event in cell death
    • Mugford C.A., Carfagna M.A., Kedderis G.L. Furan-mediated uncoupling of hepatic oxidative phosphorylation in Fischer-344 rats: an early event in cell death. Toxicol Appl Pharmacol 1997, 144:1-11.
    • (1997) Toxicol Appl Pharmacol , vol.144 , pp. 1-11
    • Mugford, C.A.1    Carfagna, M.A.2    Kedderis, G.L.3
  • 54
    • 0347813626 scopus 로고
    • Effects of processing on liquid infant milk formulas: I. Freshly processed products
    • Mulchandani R.P., Josephson R.V., Harper W.J. Effects of processing on liquid infant milk formulas: I. Freshly processed products. J Diary Sci 1979, 62:1527-1536.
    • (1979) J Diary Sci , vol.62 , pp. 1527-1536
    • Mulchandani, R.P.1    Josephson, R.V.2    Harper, W.J.3
  • 55
    • 33748939082 scopus 로고    scopus 로고
    • Analysis of 5-hydroxymethylfurfural in coffee, dried fruits and urine
    • press
    • Murkovic M., Pichler N. Analysis of 5-hydroxymethylfurfural in coffee, dried fruits and urine. Mol Nutrit Food Res 2006, in press.
    • (2006) Mol Nutrit Food Res
    • Murkovic, M.1    Pichler, N.2
  • 56
    • 0024456345 scopus 로고
    • Chromosome aberrations induced by pyrolysates of carbohydrates in Chinese hamster V79 cells
    • Nishi Y., Miyakawa Y., Kato K. Chromosome aberrations induced by pyrolysates of carbohydrates in Chinese hamster V79 cells. Mutation Res 1989, 227:117-123.
    • (1989) Mutation Res , vol.227 , pp. 117-123
    • Nishi, Y.1    Miyakawa, Y.2    Kato, K.3
  • 57
    • 0026522110 scopus 로고
    • Comparative metabolism and disposition of furfural and furfuryl alcohol in rats
    • Nomeir A.A., Silveira D.M., McComish M.F., Chadwick M. Comparative metabolism and disposition of furfural and furfuryl alcohol in rats. Drug Metab Dispos 1992, 20:198-204.
    • (1992) Drug Metab Dispos , vol.20 , pp. 198-204
    • Nomeir, A.A.1    Silveira, D.M.2    McComish, M.F.3    Chadwick, M.4
  • 58
    • 84903651035 scopus 로고
    • 1 mice (gavage studies) Natl Toxicol Program Tech Report Series
    • 1 mice (gavage studies). Natl Toxicol Program Tech Report Series 1990, 1-201.
    • (1990) , pp. 1-201
  • 59
    • 84903656444 scopus 로고
    • 1 mice (gavage studies) Natl Toxicol Program Tech Report Series
    • 1 mice (gavage studies). Natl Toxicol Program Tech Report Series 1993, 1-287.
    • (1993) , pp. 1-287
  • 60
    • 84903654160 scopus 로고    scopus 로고
    • 1 mice (inhalation studies) Natl Toxicol Program Tech Report Series
    • 1 mice (inhalation studies). Natl Toxicol Program Tech Report Series 1999, 1-248.
    • (1999) , pp. 1-248
  • 62
    • 0033914808 scopus 로고    scopus 로고
    • A reactive metabolite of furan, cis-2-butene-1,4-dial, is mutagenic in the Ames assay
    • Peterson L.A., Naruko K.C., Predecki D.P. A reactive metabolite of furan, cis-2-butene-1,4-dial, is mutagenic in the Ames assay. Chem Res Toxicol 2000, 13:531-534.
    • (2000) Chem Res Toxicol , vol.13 , pp. 531-534
    • Peterson, L.A.1    Naruko, K.C.2    Predecki, D.P.3
  • 63
    • 24944560423 scopus 로고    scopus 로고
    • Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial
    • Peterson L.A., Cummings M.E., Vu C.C., Matter B.A. Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial. Drug Metab Dispos 2005, 33:1453-1458.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1453-1458
    • Peterson, L.A.1    Cummings, M.E.2    Vu, C.C.3    Matter, B.A.4
  • 64
    • 0015408508 scopus 로고
    • The identification and metabolic origin of 2-furoylglycine and 2,5-furandicarboxylic acid in human urine
    • Pettersen J.E., Jellum E. The identification and metabolic origin of 2-furoylglycine and 2,5-furandicarboxylic acid in human urine. Clin Chim Acta 1972, 41:199-207.
    • (1972) Clin Chim Acta , vol.41 , pp. 199-207
    • Pettersen, J.E.1    Jellum, E.2
  • 66
    • 0015150716 scopus 로고
    • Histopathology of renal lipomatous tumors in rats treated with the "natural" products, pyrrolizidine alkaloids and α, β-unsaturated aldehydes
    • Schoental R., Hard G.C., Gibbard S. Histopathology of renal lipomatous tumors in rats treated with the "natural" products, pyrrolizidine alkaloids and α, β-unsaturated aldehydes. J Natl Cancer Inst 1971, 47:1037-1044.
    • (1971) J Natl Cancer Inst , vol.47 , pp. 1037-1044
    • Schoental, R.1    Hard, G.C.2    Gibbard, S.3
  • 67
    • 0023026745 scopus 로고
    • Experimental studies on hepatic cirrhosis and hepatocarcinogenesis. II. Influence of cirrhotic liver on 2-FAA hepatocarcinogenesis in rats
    • Shimizu A. Experimental studies on hepatic cirrhosis and hepatocarcinogenesis. II. Influence of cirrhotic liver on 2-FAA hepatocarcinogenesis in rats. Acta Pathol Jpn 1986, 36:1039-1048.
    • (1986) Acta Pathol Jpn , vol.36 , pp. 1039-1048
    • Shimizu, A.1
  • 68
    • 0008502497 scopus 로고
    • Furans as the mutagens formed by aminocarbonyl reactions
    • Shinohara K., Kim E.-H., Omura H. Furans as the mutagens formed by aminocarbonyl reactions. Dev Food Sci 1986, 13:353-362.
    • (1986) Dev Food Sci , vol.13 , pp. 353-362
    • Shinohara, K.1    Kim, E.-H.2    Omura, H.3
  • 69
    • 0014441988 scopus 로고
    • [Toxico-hygienic characteristics of oxymethylfurfural]
    • Simonyan T.A. [Toxico-hygienic characteristics of oxymethylfurfural]. Vopr Pitan 1969, 28:54-58.
    • (1969) Vopr Pitan , vol.28 , pp. 54-58
    • Simonyan, T.A.1
  • 70
    • 0015145899 scopus 로고
    • [Hygienic assessment of the oxymethylfurfurol content in a daily food ration of man]
    • Simonyan T.A. [Hygienic assessment of the oxymethylfurfurol content in a daily food ration of man]. Vopr Pitan 1971, 30:50-53.
    • (1971) Vopr Pitan , vol.30 , pp. 50-53
    • Simonyan, T.A.1
  • 72
    • 84890513393 scopus 로고    scopus 로고
    • Handbook of Enzyme Systems that Metabolise Drugs and Other Xenobiotics
    • John Wiley & Sons, Sussex, C. Ioannides (Ed.)
    • Steventon G.B., Hutt A.J. Handbook of Enzyme Systems that Metabolise Drugs and Other Xenobiotics. The amino acid conjugations 2002, 501-520. John Wiley & Sons, Sussex. C. Ioannides (Ed.).
    • (2002) The amino acid conjugations , pp. 501-520
    • Steventon, G.B.1    Hutt, A.J.2
  • 73
    • 0028222204 scopus 로고
    • Activation of the Maillard reaction product 5-(hydroxymethyl)furfural to strong mutagens via allylic sulfonation and chlorination
    • Surh Y.J., Tannenbaum S.R. Activation of the Maillard reaction product 5-(hydroxymethyl)furfural to strong mutagens via allylic sulfonation and chlorination. Chem Res Toxicol 1994, 7:313-318.
    • (1994) Chem Res Toxicol , vol.7 , pp. 313-318
    • Surh, Y.J.1    Tannenbaum, S.R.2
  • 74
    • 0027973158 scopus 로고
    • 5-sulfooxymethylfurfural as a possible ultimate mutagenic and carcinogenic metabolite of the Maillard reaction product, 5-hydroxymethylfurfural
    • Surh Y.J., Liem A., Miller J.A., Tannenbaum S.R. 5-sulfooxymethylfurfural as a possible ultimate mutagenic and carcinogenic metabolite of the Maillard reaction product, 5-hydroxymethylfurfural. Carcinogenesis 1994, 15:2375-2377.
    • (1994) Carcinogenesis , vol.15 , pp. 2375-2377
    • Surh, Y.J.1    Liem, A.2    Miller, J.A.3    Tannenbaum, S.R.4
  • 75
    • 0030904673 scopus 로고    scopus 로고
    • High sulfotransferase activity for phenolic aromatic odorants present in the mouse olfactory organ
    • Tamura H., Miyawaki A., Inoh N., Harada Y., Mikoshiba K., Matsui M. High sulfotransferase activity for phenolic aromatic odorants present in the mouse olfactory organ. Chem-Biol Interact 1997, 104:1-9.
    • (1997) Chem-Biol Interact , vol.104 , pp. 1-9
    • Tamura, H.1    Miyawaki, A.2    Inoh, N.3    Harada, Y.4    Mikoshiba, K.5    Matsui, M.6
  • 76
    • 0032079687 scopus 로고    scopus 로고
    • Molecular cloning and expression of a cDNA encoding an olfactory-specific mouse phenol sulphotransferase
    • Tamura H., Harada Y., Miyawaki A., Mikoshiba K., Matsui M. Molecular cloning and expression of a cDNA encoding an olfactory-specific mouse phenol sulphotransferase. Biochem J 1998, 331:953-958.
    • (1998) Biochem J , vol.331 , pp. 953-958
    • Tamura, H.1    Harada, Y.2    Miyawaki, A.3    Mikoshiba, K.4    Matsui, M.5
  • 77
    • 0001514718 scopus 로고    scopus 로고
    • Determination of 5-hydroxymethylfurfural in vinegar samples by HPLC
    • Theobald A., Mûller A., Anklam E. Determination of 5-hydroxymethylfurfural in vinegar samples by HPLC. J Agr Food Chem 1998, 46:1850-1854.
    • (1998) J Agr Food Chem , vol.46 , pp. 1850-1854
    • Theobald, A.1    Mûller, A.2    Anklam, E.3
  • 78
    • 0021722064 scopus 로고
    • A review of 5-hydroxymethylfurfural (HMF) in parenteral solutions
    • Ulbricht R.J., Northup S.J., Thomas J.A. A review of 5-hydroxymethylfurfural (HMF) in parenteral solutions. Fundam Appl Toxicol 1984, 4:843-853.
    • (1984) Fundam Appl Toxicol , vol.4 , pp. 843-853
    • Ulbricht, R.J.1    Northup, S.J.2    Thomas, J.A.3
  • 79
    • 0021281831 scopus 로고
    • Toxicity-distribution relationships among 3-alkylfurans in mouse liver and kidney
    • Wiley R.A., Traiger G.J., Baraban S., Gammal L.M. Toxicity-distribution relationships among 3-alkylfurans in mouse liver and kidney. Toxicol Appl Pharmacol 1984, 74:1-9.
    • (1984) Toxicol Appl Pharmacol , vol.74 , pp. 1-9
    • Wiley, R.A.1    Traiger, G.J.2    Baraban, S.3    Gammal, L.M.4
  • 80
    • 0026603074 scopus 로고
    • Evaluation of genotoxicity, pathological lesions, and cell proliferation in livers of rats and mice treated with furan
    • Wilson D.M., Goldsworthy T.L., Popp J.A., Butterworth B.E. Evaluation of genotoxicity, pathological lesions, and cell proliferation in livers of rats and mice treated with furan. Environ Mol Mutagen 1992, 19:209-222.
    • (1992) Environ Mol Mutagen , vol.19 , pp. 209-222
    • Wilson, D.M.1    Goldsworthy, T.L.2    Popp, J.A.3    Butterworth, B.E.4
  • 81
    • 0027196817 scopus 로고
    • Initiation and promotion of colonic aberrant crypt foci in rats by 5-hydroxymethyl-2-furaldehyde in thermolyzed sucrose
    • Zhang X.-M., Chan C.C., Stamp D., Minkin S., Archer M.C., Bruce W.R. Initiation and promotion of colonic aberrant crypt foci in rats by 5-hydroxymethyl-2-furaldehyde in thermolyzed sucrose. Carcinogenesis 1993, 14:773-775.
    • (1993) Carcinogenesis , vol.14 , pp. 773-775
    • Zhang, X.-M.1    Chan, C.C.2    Stamp, D.3    Minkin, S.4    Archer, M.C.5    Bruce, W.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.