Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling

Chemical Research in Toxicology

Volumn 21, Issue 10, 2008, Pages 2017-2025

  Morden, Bernhard H ^a   Müller, Carolin ^a   Engst, Wolfram ^a   Frank, Heinz ^b   Seidel, Albrecht ^b   Glatt, Hansruedi ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b Prof Dr Gernot Grimmer Foundation   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLPYRENE; 1 SULFOOXYMETHYLPYRENE; 2' DEOXYNUCLEOSIDE; ADENOSINE DERIVATIVE; GUANOSINE DERIVATIVE; N2 (1 METHYLPYRENYL) 2' DEOXYGUANOSINE; N6 (1 METHYLPYRENYL) 2' DEOXYADENOSINE; PHOSPHORUS 32; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA ADDUCT; ENZYME METABOLISM; HERRING; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM ALLOWABLE CONCENTRATION; NONHUMAN; SOLID PHASE EXTRACTION;

ANIMALS; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DEOXYADENOSINES; DEOXYGUANOSINE; DNA ADDUCTS; INDICATOR DILUTION TECHNIQUES; LIVER; MALE; MOLECULAR STRUCTURE; PHOSPHORUS RADIOISOTOPES; PYRENES; RATS; RATS, WISTAR; SPERMATOZOA; TANDEM MASS SPECTROMETRY; TIME FACTORS;

CLUPEIDAE; RATTUS; RODENTIA;

EID: 55949137448     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx800217d     Document Type: Article

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