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Volumn 82, Issue 2, 2012, Pages 226-235

γ-hydroxybutyrate (GHB)-induced respiratory depression: Combined receptor-transporter inhibition therapy for treatment in GHB overdose

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBUTYRIC ACID; 5,5 DIMETHYL 2 MORPHOLINEACETIC ACID; BICUCULLINE; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER;

EID: 84863884501     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.078154     Document Type: Article
Times cited : (44)

References (37)
  • 4
    • 4644323282 scopus 로고    scopus 로고
    • Fatalities associated with the use of γ-hydroxybutyrate and its analogues in Australasia
    • Caldicott DG, Chow FY, Burns BJ, Felgate PD, and Byard RW (2004) Fatalities associated with the use of γ-hydroxybutyrate and its analogues in Australasia. Med J Aust 181:310-313.
    • (2004) Med J Aust , vol.181 , pp. 310-313
    • Caldicott, D.G.1    Chow, F.Y.2    Burns, B.J.3    Felgate, P.D.4    Byard, R.W.5
  • 6
    • 20444492015 scopus 로고    scopus 로고
    • Resuscitative effect of a γ-aminobutyric acid B receptor antagonist on γ-hydroxybutyric acid mortality in mice
    • Carai MA, Colombo G, and Gessa GL (2005) Resuscitative effect of a γ-aminobutyric acid B receptor antagonist on γ-hydroxybutyric acid mortality in mice. Ann Emerg Med 45:614-619.
    • (2005) Ann Emerg Med , vol.45 , pp. 614-619
    • Carai, M.A.1    Colombo, G.2    Gessa, G.L.3
  • 7
    • 79957519725 scopus 로고    scopus 로고
    • Use of a local sensitivity analysis to inform study design based on a mechanistic toxicokinetic model for γ-hydroxybutyric acid
    • Felmlee MA, Krzyzanski W, Morse BL, and Morris ME (2011) Use of a local sensitivity analysis to inform study design based on a mechanistic toxicokinetic model for γ-hydroxybutyric acid. AAPS J 13:240-254.
    • (2011) AAPS J , vol.13 , pp. 240-254
    • Felmlee, M.A.1    Krzyzanski, W.2    Morse, B.L.3    Morris, M.E.4
  • 8
    • 77952386385 scopus 로고    scopus 로고
    • Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid
    • Felmlee MA, Roiko SA, Morse BL, and Morris ME (2010a) Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid. J Pharmacol Exp Ther 333:764-771.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 764-771
    • Felmlee, M.A.1    Roiko, S.A.2    Morse, B.L.3    Morris, M.E.4
  • 9
    • 77955979548 scopus 로고    scopus 로고
    • Mechanistic toxicokinetic model for γ-hydroxybutyric acid: Inhibition of active renal reabsorption as a potential therapeutic strategy
    • Felmlee MA, Wang Q, Cui D, Roiko SA, and Morris ME (2010b) Mechanistic toxicokinetic model for γ-hydroxybutyric acid: inhibition of active renal reabsorption as a potential therapeutic strategy. AAPS J 12:407-416.
    • (2010) AAPS J , vol.12 , pp. 407-416
    • Felmlee, M.A.1    Wang, Q.2    Cui, D.3    Roiko, S.A.4    Morris, M.E.5
  • 10
    • 2942615356 scopus 로고    scopus 로고
    • Liquid chromatographicmass spectrometric determination of endogenous gamma-hydroxybutyrate concentrations in rat brain regions and plasma
    • Fung HL, Haas E, Raybon J, Xu J, and Fung SM (2004) Liquid chromatographicmass spectrometric determination of endogenous gamma-hydroxybutyrate concentrations in rat brain regions and plasma. J Chromatogr B Analyt Technol Biomed Life Sci 807:287-291.
    • (2004) J Chromatogr B Analyt Technol Biomed Life Sci , vol.807 , pp. 287-291
    • Fung, H.L.1    Haas, E.2    Raybon, J.3    Xu, J.4    Fung, S.M.5
  • 11
    • 51249111276 scopus 로고    scopus 로고
    • Pharmacokinetics of 1,4-butanediol in rats: Bioactivation to γ-hydroxybutyric acid, interaction with ethanol, and oral bioavailability
    • Fung HL, Tsou PS, Bulitta JB, Tran DC, Page NA, Soda D, and Mi Fung S (2008) Pharmacokinetics of 1,4-butanediol in rats: bioactivation to γ-hydroxybutyric acid, interaction with ethanol, and oral bioavailability. AAPS J 10:56-69.
    • (2008) AAPS J , vol.10 , pp. 56-69
    • Fung, H.L.1    Tsou, P.S.2    Bulitta, J.B.3    Tran, D.C.4    Page, N.A.5    Soda, D.6    Mi Fung, S.7
  • 12
    • 79956338187 scopus 로고    scopus 로고
    • Liquid ecstasy intoxication: Clinical features of 505 consecutive emergency department patients
    • Galicia M, Nogue S, and Miró O (2011) Liquid ecstasy intoxication: clinical features of 505 consecutive emergency department patients. Emerg Med J 28:462-466.
    • (2011) Emerg Med J , vol.28 , pp. 462-466
    • Galicia, M.1    Nogue, S.2    Miró, O.3
  • 13
    • 0033005441 scopus 로고    scopus 로고
    • γ-Hydroxybutyrate modulates synthesis and extracellular concentration of gamma-aminobutyric acid in discrete rat brain regions in vivo
    • Gobaille S, Hechler V, Andriamampandry C, Kemmel V, and Maitre M (1999) γ-Hydroxybutyrate modulates synthesis and extracellular concentration of gamma-aminobutyric acid in discrete rat brain regions in vivo. J Pharmacol Exp Ther 290:303-309.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 303-309
    • Gobaille, S.1    Hechler, V.2    Andriamampandry, C.3    Kemmel, V.4    Maitre, M.5
  • 15
    • 0030926435 scopus 로고    scopus 로고
    • γ-Hydroxybutyrate conversion into GABA induces displacement of GABAB binding that is blocked by valproate and ethosuximide
    • Hechler V, Ratomponirina C, and Maitre M (1997) γ-Hydroxybutyrate conversion into GABA induces displacement of GABAB binding that is blocked by valproate and ethosuximide. J Pharmacol Exp Ther 281:753-760.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 753-760
    • Hechler, V.1    Ratomponirina, C.2    Maitre, M.3
  • 17
    • 50549200488 scopus 로고
    • Sodium 4-hydroxybutyrate
    • Laborit H (1964) Sodium 4-hydroxybutyrate. Int J Neuropharmacol 3:433-451.
    • (1964) Int J Neuropharmacol , vol.3 , pp. 433-451
    • Laborit, H.1
  • 19
    • 0018176540 scopus 로고
    • Improved pharmacological activity via pro-drug modification: Comparative pharmacokinetics of sodium γ-hydroxybutyrate and γ-butyrolactone
    • Lettieri J and Fung HL (1978) Improved pharmacological activity via pro-drug modification: comparative pharmacokinetics of sodium γ-hydroxybutyrate and γ-butyrolactone. Res Commun Chem Pathol Pharmacol 22:107-118.
    • (1978) Res Commun Chem Pathol Pharmacol , vol.22 , pp. 107-118
    • Lettieri, J.1    Fung, H.L.2
  • 20
    • 0018372970 scopus 로고
    • Dose-dependent pharmacokinetics and hypnotic effects of sodium γ-hydroxybutyrate in the rat
    • Lettieri JT and Fung HL (1979) Dose-dependent pharmacokinetics and hypnotic effects of sodium γ-hydroxybutyrate in the rat. J Pharmacol Exp Ther 208:7-11.
    • (1979) J Pharmacol Exp Ther , vol.208 , pp. 7-11
    • Lettieri, J.T.1    Fung, H.L.2
  • 21
    • 0031745926 scopus 로고    scopus 로고
    • A tale of novel intoxication: Seven cases of γ-hydroxybutyric acid overdose
    • Li J, Stokes SA, and Woeckener A (1998) A tale of novel intoxication: seven cases of γ-hydroxybutyric acid overdose. Ann Emerg Med 31:723-728.
    • (1998) Ann Emerg Med , vol.31 , pp. 723-728
    • Li, J.1    Stokes, S.A.2    Woeckener, A.3
  • 22
    • 6344259978 scopus 로고    scopus 로고
    • γ-Hydroxybutyrate (GHB) and γ-butyrolactone (GBL): Analysis of overdose cases reported to the Swiss Toxicological Information Centre
    • Liechti ME and Kupferschmidt H (2004) γ-Hydroxybutyrate (GHB) and γ-butyrolactone (GBL): analysis of overdose cases reported to the Swiss Toxicological Information Centre. Swiss Med Wkly 134:534-537.
    • (2004) Swiss Med Wkly , vol.134 , pp. 534-537
    • Liechti, M.E.1    Kupferschmidt, H.2
  • 23
    • 0030895783 scopus 로고    scopus 로고
    • The γ-hydroxybutyrate signalling system in brain: Organization and functional implications
    • MaitreM(1997) The γ-hydroxybutyrate signalling system in brain: organization and functional implications. Prog Neurobiol 51:337-361.
    • (1997) Prog Neurobiol , vol.51 , pp. 337-361
    • Maitre, M.1
  • 24
    • 0036308018 scopus 로고    scopus 로고
    • γ Hydroxybutyric acid (GHB) intoxication
    • Mason PE and Kerns WP 2nd (2002) γ Hydroxybutyric acid (GHB) intoxication. Acad Emerg Med 9:730-739.
    • (2002) Acad Emerg Med , vol.9 , pp. 730-739
    • Mason, P.E.1    Kerns II, W.P.2
  • 25
    • 0022501687 scopus 로고
    • Inhibition of lactate removal by ketone bodies in rat liver. Evidence for a quantitatively important role of the plasma membrane lactate transporter in lactate metabolism
    • Metcalfe HK, Monson JP, Welch SG, and Cohen RD (1986) Inhibition of lactate removal by ketone bodies in rat liver. Evidence for a quantitatively important role of the plasma membrane lactate transporter in lactate metabolism. J Clin Invest 78:743-747.
    • (1986) J Clin Invest , vol.78 , pp. 743-747
    • Metcalfe, H.K.1    Monson, J.P.2    Welch, S.G.3    Cohen, R.D.4
  • 26
    • 19444362090 scopus 로고    scopus 로고
    • Renal clearance of γ-hydroxybutyric acid in rats: Increasing renal elimination as a detoxification strategy
    • Morris ME, Hu K, and Wang Q (2005) Renal clearance of γ-hydroxybutyric acid in rats: increasing renal elimination as a detoxification strategy. J Pharmacol Exp Ther 313:1194-1202.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 1194-1202
    • Morris, M.E.1    Hu, K.2    Wang, Q.3
  • 27
    • 84863936468 scopus 로고    scopus 로고
    • Monocarboxylate transporter inhibition with osmotic diuresis increases γ-hydroxybutyrate renal elimination in humans: A proof-of-concept study
    • Morris ME, Morse BL, Baciewicz GJ, Tessena MM, Acquisto NM, Hutchinson DJ, and DiCenzo R (2011) Monocarboxylate transporter inhibition with osmotic diuresis increases γ-hydroxybutyrate renal elimination in humans: a proof-of-concept study. J Clinic Toxicol 1.
    • (2011) J Clinic Toxicol , vol.1
    • Morris, M.E.1    Morse, B.L.2    Baciewicz, G.J.3    Tessena, M.M.4    Acquisto, N.M.5    Hutchinson, D.J.6    DiCenzo, R.7
  • 28
    • 0036285107 scopus 로고    scopus 로고
    • Respiratory responses to intravenous infusion of sodium lactate in male and female Wistar rats
    • Olsson M, Ho HP, Annerbrink K, Thylefors J, and Eriksson E (2002) Respiratory responses to intravenous infusion of sodium lactate in male and female Wistar rats. Neuropsychopharmacology 27:85-91.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 85-91
    • Olsson, M.1    Ho, H.P.2    Annerbrink, K.3    Thylefors, J.4    Eriksson, E.5
  • 30
    • 0037678912 scopus 로고    scopus 로고
    • γ-Hydroxybutyrate serum levels and clinical syndrome after severe overdose
    • Sporer KA, Chin RL, Dyer JE, and Lamb R (2003) γ-Hydroxybutyrate serum levels and clinical syndrome after severe overdose. Ann Emerg Med 42:3-8.
    • (2003) Ann Emerg Med , vol.42 , pp. 3-8
    • Sporer, K.A.1    Chin, R.L.2    Dyer, J.E.3    Lamb, R.4
  • 31
    • 82955244458 scopus 로고    scopus 로고
    • Substance Abuse and Mental Health Services Administration HHS Publ. No. SMA 11-4618. Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality, Rockville, MD
    • Substance Abuse and Mental Health Services Administration (2011) Drug Abuse Warning Network, 2008: National Estimates of Drug-Related Emergency Department Visits. HHS Publ. No. SMA 11-4618. Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality, Rockville, MD.
    • (2011) Drug Abuse Warning Network, 2008: National Estimates of Drug-Related Emergency Department Visits
  • 32
    • 0029797632 scopus 로고    scopus 로고
    • Effects of sodium lactate on ventilation and acid-base balance in healthy humans
    • Tappy L, Cayeux MC, and Chioléro R (1996) Effects of sodium lactate on ventilation and acid-base balance in healthy humans. Clin Physiol 16:393-401.
    • (1996) Clin Physiol , vol.16 , pp. 393-401
    • Tappy, L.1    Cayeux, M.C.2    Chioléro, R.3
  • 33
    • 33745955759 scopus 로고    scopus 로고
    • Transport of γ-hydroxybutyrate in rat kidney membrane vesicles: Role of monocarboxylate transporters
    • Wang Q, Darling IM, and Morris ME (2006) Transport of γ-hydroxybutyrate in rat kidney membrane vesicles: role of monocarboxylate transporters. J Pharmacol Exp Ther 318:751-761.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 751-761
    • Wang, Q.1    Darling, I.M.2    Morris, M.E.3
  • 34
    • 34547218143 scopus 로고    scopus 로고
    • The role of monocarboxylate transporter 2 and 4 in the transport of γ-hydroxybutyric acid in mammalian cells
    • Wang Q and Morris ME (2007) The role of monocarboxylate transporter 2 and 4 in the transport of γ-hydroxybutyric acid in mammalian cells. Drug Metab Dispos 35:1393-1399.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1393-1399
    • Wang, Q.1    Morris, M.E.2
  • 35
    • 54349112350 scopus 로고    scopus 로고
    • Effects of L-lactate and D-mannitol on γ-hydroxybutyrate toxicokinetics and toxicodynamics in rats
    • Wang Q, Wang X, and Morris ME (2008a) Effects of L-lactate and D-mannitol on γ-hydroxybutyrate toxicokinetics and toxicodynamics in rats. Drug Metab Dispos 36:2244-2251.
    • (2008) Drug Metab Dispos , vol.36 , pp. 2244-2251
    • Wang, Q.1    Wang, X.2    Morris, M.E.3
  • 36
    • 51249090528 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between the flavonoid luteolin and γ-hydroxybutyrate in rats: Potential involvement of monocarboxylate transporters
    • Wang X, Wang Q, and Morris ME (2008b) Pharmacokinetic interaction between the flavonoid luteolin and γ-hydroxybutyrate in rats: potential involvement of monocarboxylate transporters. AAPS J 10:47-55.
    • (2008) AAPS J , vol.10 , pp. 47-55
    • Wang, X.1    Wang, Q.2    Morris, M.E.3
  • 37
    • 79951909577 scopus 로고    scopus 로고
    • Case series of 226 γ-hydroxybutyrate-associated deaths: Lethal toxicity and trauma
    • Zvosec DL, Smith SW, Porrata T, Strobl AQ, and Dyer JE (2011) Case series of 226 γ-hydroxybutyrate-associated deaths: lethal toxicity and trauma. Am J Emerg Med 29:319-332.
    • (2011) Am J Emerg Med , vol.29 , pp. 319-332
    • Zvosec, D.L.1    Smith, S.W.2    Porrata, T.3    Strobl, A.Q.4    Dyer, J.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.