A comparison of Drosophila melanogaster detoxification gene induction responses for six insecticides, caffeine and phenobarbital

Insect Biochemistry and Molecular Biology

Volumn 36, Issue 12, 2006, Pages 934-942

  Willoughby, Lee ^a   Chung, Henry ^a   Lumb, Chris ^a   Robin, Charles ^b   Batterham, Philip ^a   Daborn, Phillip J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Cytochrome P450; Gene expression; Glutathione S transferase; Insecticide; Insecticide resistance; Microarray

Indexed keywords

CAFFEINE; CYTOCHROME P450; DROSOPHILA PROTEIN; ESTERASE; GLUTATHIONE TRANSFERASE; INSECTICIDE; PHENOBARBITAL;

ANIMAL; ARTICLE; COMPARATIVE STUDY; DROSOPHILA MELANOGASTER; DRUG DETOXIFICATION; DRUG EFFECT; ENZYME INDUCTION; GENE EXPRESSION PROFILING; GENETICS;

ANIMALS; CAFFEINE; CYTOCHROME P-450 ENZYME SYSTEM; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENZYME INDUCTION; ESTERASES; GENE EXPRESSION PROFILING; GLUTATHIONE TRANSFERASE; INSECTICIDES; METABOLIC DETOXICATION, DRUG; PHENOBARBITAL;

DROSOPHILA MELANOGASTER; INSECTA;

EID: 33845973725     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2006.09.004     Document Type: Article

References (48)

1. Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., and George R.A. The genome sequence of Drosophila melanogaster. Science 287 (2000) 2185-2195
2. Amichot M., Brun A., Cuany A., De Souza G., Le Mouel T., Bride J.M., Babault M., Salaun J.P., Rahmani R., and Berge J.B. Induction of cytochrome P450 activities in Drosophila melanogaster strains susceptible or resistant to insecticides. Comp. Biochem. Physiol. C-Pharmacol. Toxicol. Endocrinol. 121 1-3 (1998) 311-319
3. Amichot A., Tares S., Brun-Barale A., Arthaud L., Bride J.M., and Berge J.B. Point mutations associated with insecticide resistance in the Drosophila cytochrome P450 Cyp6a2 enable DDT metabolism. Eur. J. Biochem. 271 (2004) 1250-1257
4. Berge J.B., Feyereisen R., and Amichot M. Cytochrome P450 monooxygenases and insecticide resistance in insects. Philos. Trans. R. Soc. London B 353 (1998) 1701-1705
5. Bogwitz M.R., Chung H., Magoc L., Rigby S., Wong W., O'Keefe M., McKenzie J.A., Batterham P., and Daborn P.J. Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster. PNAS 102 36 (2005) 12807-12812
6. Brandt A., Scharf M.E., Pedra J.H.F., Holmes G., Dean A., Kreitman M., and Pittendrigh B.R. Differential expression and induction of two Drosophila cytochrome P450 genes near the Rst(2)DDT locus. Insect Mol. Biol. 11 (2002) 337-341
7. Brun A., Cuany A., Le Mouel T., Berge J., and Amichot M. Inducibility of the Drosophila melanogaster cytochrome P450 gene, CYP6A2, by phenobarbital in insecticide susceptible or resistant strains. Insect Biochem. Mol. Biol. 26 7 (1996) 697-703
8. Carino F.A., Koener J.F., Plapp F.W.J., and Feyereisen R. Expression of the cytochrome P450 gene Cyp6A1 in the house fly, Musca domestica. ACS Symp. Ser. 505 (1992) 31-40
9. Chen J., and Raymond K. Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involved the nuclear pregnane X receptor. Ann. Clin. Microbiol. Antimicrob. 15 (2006) 3
10. Cohen M.B., Schuler M.A., and Berenbaum M.R. A host-inducible cytochrome P450 from a host-specific caterpillar: molecular cloning and evolution. PNAS 89 (1992) 10920-10924
11. Coleman M., Vontas J.G., and Hemingway J. Molecular characterization of the amplified aldehyde oxidase from insecticide resistant Culex quinquefasciatus. Eur. J. Biochem. 269 (2002) 768-779
12. Daborn P.J., Yen J.L., Bogwitz M.R., Le Goff G., Feil E., Jeffers S., Tijet N., Perry T., Heckel D., Batterham P., Feyereisen R., Wilson T.G., and ffrench-Constant R.H. A single P450 allele associated with insecticide resistance in Drosophila. Science 297 (2002) 2253-2256
13. Danielson P.B., MacIntyre R.J., and Fogleman J.C. Molecular cloning of a family of xenobiotic-inducible drosophilid cytochrome P450s: evidence for involvement in host-plant allelochemical resistance. PNAS 94 (1997) 10797-10802
14. Denison M.S., and Nagy S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43 (2003) 309-334
15. Dunkov B.C., Guzov V.M., Mocelin G., Shotkoski F., Brun A., Amichot M., ffrench-Constant R.H., and Feyereisen R. The Drosophila cytochrome P450 gene Cyp6a2: structure, localization, heterologous expression, and induction by phenobarbital. DNA Cell Biol. 16 11 (1997) 1345-1356
16. Ellinger-Ziegelbauer H., Stuart B., Wahle B., Bomann W., and Ahr H.J. Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in the rat liver. Mutat. Res. 575 (2005) 61-84
17. Field L.M., Devonshire A.L., and Forde B.G. Molecular evidence that insecticide resistance in peach-potato aphids (Myzus persicae Sulz.) results from amplification of an esterase gene. Biochem. J. 251 (1988) 309-312
18. Field L.M., Blackman R.L., Tyler-Smith C., and Devonshire A.L. Relationship between amount of esterase and gene copy number in insecticide-resistant Myzus persicae (Sulzer). Biochem. J. 339 (1999) 737-742
19. Goadstuff T., Dreano Y., Guillos B., Menez J.-F., and Berthou F. Induction of liver and kidney CYP1A1/CYP1A2 by caffeine in rat. Biochem. Pharmcol. 52 (1996) 1915-1919
20. Goodwin B., Redinbo M.R., and Kliewer S.A. Regulation of CYP3A gene transcription by the pregnane X receptor. Annu. Rev. Pharm. Toxicol. 42 (2002) 1-23
21. Honkakoski P., Zelko I., Sueyoshi T., and Negishi M. The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol. Cell Biol. 18 (1998) 5652-5658
22. Hung C.-F., Harrison T.L., Berenbaum M.R., and Schuler M.A. CYP6B3: a second furanocoumarin-inducible cytochrome P450 expressed in Papilio polyxenes. Insect Mol. Biol. 4 (1995) 149-160
23. Jensen H.R., Scott I.M., Sims S., Trudeau V.L., and Arnason J.T. Gene expression profiles of Drosophila melanogaster exposed to an insecticidal extract of Piper nigrum. J. Agric. Food Chem. 54 (2006) 1289-1295
24. King-Jones K., Horner M.A., Lam G., and Thummel C.S. The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila. Cell Metab. 4 1 (2006) 37-48
25. Kodama S., and Negishi M. Phenobarbital confers its diverse effects by activating the orphan nuclear receptor car. Drug Metab. Rev. 38 1-2 (2006) 75-87
26. Le Goff G., Boundy S., Daborn P.J., Yen J.L., Sofer L., Lind R., Sabourault C., Madi-Ravazzi L., and ffrench-Constant R.H. Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila. Insect Biochem. Mol. Biol. 33 7 (2003) 701-708
27. Le Goff G., Hilliou F., Siegfried B.D., Boundy S., Wajnberg E., Sofer L., Audant P., ffrench-Constant R.H., and Feyereisen R. Xenobiotic response in Drosophila melanogaster: sex dependence of P450 and GST gene induction. Insect Biochem. Mol. Biol. 36 8 (2006) 674-682
28. Li X., Baudry J., Berenbaum M.R., and Schuler M.A. Structural and functional divergence of insect CYP6B proteins: from specialist to generalist cytochrome P450. PNAS 101 (2003) 2939-2944
29. Luo G., Guenthner T., Gan L.S., and Humphreys W.G. CYP3A4 induction by xenobiotics: biochemistry, experimental methods and impact on drug discovery and development. Curr. Drug Metab. 5 (2004) 483-505
30. Maitra S., Dombrowski S.M., Waters L.C., and Ganguly R. Three second chromosome-linked clustered Cyp6 genes show differential constitutive and barbital-induced expression in DDT-resistant and susceptible strains of Drosophila melanogaster. Gene 180 1-2 (1996) 165-171
31. Meyer U.A., and Hoffmann K. Phenobarbital-mediated changes in gene expression in the liver. Drug Metab. Rev. 31 2 (1999) 365-373
32. Newcomb R.D., Campbell P.M., Ollis D.L., Cheah E., Russell R.J., and Oakeshott J.G. A single amino acid substitution converts a carboxylesterase to an organophosphorous hydrolase and confers insecticide resistance on a blowfly. Proc. Natl. Acad. Sci. USA 94 (1997) 7464-7468
33. Ogino Y., Itakura T., Mitsuo R., and Sato M. Induction of two forms of eel cytochrome P450 1A genes by 3-methylcholanthrene. Mar. Biotechnol. 1 (1998) 342-345
34. Ortelli F., Rossiter L.C., Vontas J., Ranson H., and Hemingway J. Heterologous expression of four glutathione transferase genes genetically linked to a major insecticide-resistance locus from the malaria vector Anopheles gambiae. Biochem. J. 373 (2003) 957-963
35. Petersen R.A., Zangerl A.R., Berenbaum M.R., and Schuler M.A. Expression of CYP6B1 and CYP6B3 cytochrome P450 monoxygenases and furanocoumarin metabolism in different tissues of Papiloi polyxenes (Lepidoptera: Papilionidae). Insect Biochem. Mol. Biol. 31 (2001) 679-690
36. Ranson H., Rossiter L.C., Ortelli F., Jensen B., Wang X., Roth C.W., Collins F.H., and Hemingway J. Identification of a novel class of insect glutathione S-transferases involved in resistance to DDT in the malaria vector Anopheles gambiae. Biochem. J. 359 (2001) 295-304
37. Sasabe M., Wen Z., Berenbaum M.R., and Schuler M.A. Molecular analysis of Cyp312a1, a novel cytochrome P450 involved in metabolism of plant allelochemicals (furanocoumarins) and insecticides (cypermethrin) in Helicoverpa zea. Gene 338 (2004) 163-175
38. Smyth G.K., and Speed T.P. Normalization of cDNA microarray data. Methods 31 (2003) 265-273
39. Sun W., Margam V.M., Sun L., Buczkowski G., Bennett G.W., Schemerhorn B., Muir W.M., and Pittendrigh B.R. Genome-wide analysis of phenobarbital-inducible genes in Drosophila melanogaster. Insect Mol. Biol. 15 4 (2006) 455-464
40. Tang A.H., and Tu C.D. Biochemical characterization of Drosophila glutathione-S-transferases D1 and D21. J. Biol. Chem. 269 (1994) 27876-27884
41. Tautz D., and Pfeifle C. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98 (1989) 81-85
42. Vontas J.G., Small G.J., Nikou D.C., Ranson H., and Hemingway J. Purification, molecular cloning and heterologous expression of a glutathione-S-transferase involved in insecticide resistance from the rice brown planthopper, Nilaparvata lugens. Biochem. J. 362 (2002) 329-337
43. Waxman D.J. P450s gene induction by structurally diverse xenochemicals: central role of nuclear receptors Car, PXR and PPAR. Arch. Biochem. Biophys. 369 (1999) 11-23
44. Wen Z., Pan L., Berenbaum M.R., and Schuler M.A. Metabolism of linear and angular furanocoumarins by Papilio polyxenex CYP6B1 co-expressed with NADPH cytochrome P450 reductase. Insect Biochem. Mol. Biol. 33 (2003) 937-947
45. Whitlock Jr. J.P. The regulation of cytochrome P-450 gene expression. Annu. Rev. Pharmacol. Toxicol. 26 (1986) 333-369
46. Whitlock Jr. J.P. Induction of cytochrome P4501A1. Annu. Rev. Pharmacol. Toxicol. 39 (1999) 103-125
47. Wilson T.G. Resistance of Drosophila to Toxins. Annu. Rev. Entomol. 46 (2001) 545-571
48. Wilson T.G. Drosophila: sentinel of environmental toxins. Integr. Comp. Biol. 45 (2005) 127-136