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Volumn 423, Issue 4, 2012, Pages 805-812

Apolipoprotein E-knockout mice show increased titers of serum anti-nuclear and anti-dsDNA antibodies

Author keywords

Apolipoprotein E knockout mice; Apoptosis; Autoantibody; Splenomegaly; TLR4

Indexed keywords

ANTINUCLEAR ANTIBODY; APOLIPOPROTEIN E; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN G; INTERFERON REGULATORY FACTOR 3; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN BAX; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 4;

EID: 84863843214     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.06.044     Document Type: Article
Times cited : (19)

References (45)
  • 1
    • 53849105417 scopus 로고    scopus 로고
    • The autoimmune origin of atherosclerosis
    • Blasi C. The autoimmune origin of atherosclerosis. Atherosclerosis 2008, 201:17-32.
    • (2008) Atherosclerosis , vol.201 , pp. 17-32
    • Blasi, C.1
  • 2
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: a double-edged sword
    • Hansson G.K., Libby P. The immune response in atherosclerosis: a double-edged sword. Nat. Rev. Immunol. 2006, 6:508-519.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 3
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 2005, 352:1685-1695.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 5
    • 1442323800 scopus 로고    scopus 로고
    • Autoimmunity to heat shock proteins in atherosclerosis
    • Mandal K., Jahangiri M., Xu Q. Autoimmunity to heat shock proteins in atherosclerosis. Autoimmun. Rev. 2004, 3:31-37.
    • (2004) Autoimmun. Rev. , vol.3 , pp. 31-37
    • Mandal, K.1    Jahangiri, M.2    Xu, Q.3
  • 6
    • 2542498855 scopus 로고    scopus 로고
    • Autoimmune and inflammatory mechanisms in atherosclerosis
    • Wick G., Knoflach M., Xu Q. Autoimmune and inflammatory mechanisms in atherosclerosis. Annu. Rev. Immunol. 2004, 22:361-403.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 361-403
    • Wick, G.1    Knoflach, M.2    Xu, Q.3
  • 7
    • 8444252436 scopus 로고    scopus 로고
    • Tlr signaling: an emerging bridge from innate immunity to atherogenesis
    • Michelsen K.S., Doherty T.M., Shah P.K., Arditi M. Tlr signaling: an emerging bridge from innate immunity to atherogenesis. J. Immunol. 2004, 173:5901-5907.
    • (2004) J. Immunol. , vol.173 , pp. 5901-5907
    • Michelsen, K.S.1    Doherty, T.M.2    Shah, P.K.3    Arditi, M.4
  • 8
  • 9
  • 10
    • 0038803973 scopus 로고    scopus 로고
    • Apolipoprotein e modulates immune activation by acting on the antigen-presenting cell
    • Tenger C., Zhou X. Apolipoprotein e modulates immune activation by acting on the antigen-presenting cell. Immunology 2003, 109:392-397.
    • (2003) Immunology , vol.109 , pp. 392-397
    • Tenger, C.1    Zhou, X.2
  • 12
    • 0031687891 scopus 로고    scopus 로고
    • Apolipoprotein e-deficient mice have impaired innate immune responses to listeria monocytogenes in vivo
    • Roselaar S.E., Daugherty A. Apolipoprotein e-deficient mice have impaired innate immune responses to listeria monocytogenes in vivo. J. Lipid Res. 1998, 39:1740-1743.
    • (1998) J. Lipid Res. , vol.39 , pp. 1740-1743
    • Roselaar, S.E.1    Daugherty, A.2
  • 14
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki A., Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010, 327:291-295.
    • (2010) Science , vol.327 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 15
    • 77956416903 scopus 로고    scopus 로고
    • Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis
    • Huang Q., Pope R.M. Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis. J. Leukoc. Biol. 2010, 88:253-262.
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 253-262
    • Huang, Q.1    Pope, R.M.2
  • 17
    • 3242710174 scopus 로고    scopus 로고
    • Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E
    • Michelsen K.S., Wong M.H., Shah P.K., Zhang W., Yano J., Doherty T.M., Akira S., Rajavashisth T.B., Arditi M. Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc. Natl. Acad. Sci. USA 2004, 101:10679-10684.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10679-10684
    • Michelsen, K.S.1    Wong, M.H.2    Shah, P.K.3    Zhang, W.4    Yano, J.5    Doherty, T.M.6    Akira, S.7    Rajavashisth, T.B.8    Arditi, M.9
  • 18
    • 77958151180 scopus 로고    scopus 로고
    • Transgenic overexpression of anti-double-stranded DNA autoantibody and activation of toll-like receptor 4 in mice induce severe systemic lupus erythematosus syndromes
    • Lee T.P., Tang S.J., Wu M.F., Song Y.C., Yu C.L., Sun K.H. Transgenic overexpression of anti-double-stranded DNA autoantibody and activation of toll-like receptor 4 in mice induce severe systemic lupus erythematosus syndromes. J. Autoimmun. 2010, 35:358-367.
    • (2010) J. Autoimmun. , vol.35 , pp. 358-367
    • Lee, T.P.1    Tang, S.J.2    Wu, M.F.3    Song, Y.C.4    Yu, C.L.5    Sun, K.H.6
  • 19
    • 0021329465 scopus 로고
    • Animal model of human disease. Proliferative glomerulonephritis associated with polyclonal b-cell activation
    • Cavallo T., Goldman M., Lambert P.H. Animal model of human disease. Proliferative glomerulonephritis associated with polyclonal b-cell activation. Am. J. Pathol. 1984, 114:346-348.
    • (1984) Am. J. Pathol. , vol.114 , pp. 346-348
    • Cavallo, T.1    Goldman, M.2    Lambert, P.H.3
  • 21
    • 37549035051 scopus 로고    scopus 로고
    • Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of alzheimer disease
    • Cao D., Lu H., Lewis T.L., Li L. Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of alzheimer disease. J. Biol. Chem. 2007, 282:36275-36282.
    • (2007) J. Biol. Chem. , vol.282 , pp. 36275-36282
    • Cao, D.1    Lu, H.2    Lewis, T.L.3    Li, L.4
  • 22
    • 33846048569 scopus 로고    scopus 로고
    • Simvastatin enhances learning and memory independent of amyloid load in mice
    • Li L., Cao D., Kim H., Lester R., Fukuchi K. Simvastatin enhances learning and memory independent of amyloid load in mice. Ann. Neurol. 2006, 60:729-739.
    • (2006) Ann. Neurol. , vol.60 , pp. 729-739
    • Li, L.1    Cao, D.2    Kim, H.3    Lester, R.4    Fukuchi, K.5
  • 23
    • 78149360607 scopus 로고    scopus 로고
    • Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of sle
    • Munoz L.E., Janko C., Schulze C., Schorn C., Sarter K., Schett G., Herrmann M. Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of sle. Autoimmun. Rev. 2010, 10:38-42.
    • (2010) Autoimmun. Rev. , vol.10 , pp. 38-42
    • Munoz, L.E.1    Janko, C.2    Schulze, C.3    Schorn, C.4    Sarter, K.5    Schett, G.6    Herrmann, M.7
  • 24
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. Apoptosis by death factor. Cell 1997, 88:355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 25
    • 0035844867 scopus 로고    scopus 로고
    • Bax and bak coalesce into novel mitochondria-associated clusters during apoptosis
    • Nechushtan A., Smith C.L., Lamensdorf I., Yoon S.H., Youle R.J. Bax and bak coalesce into novel mitochondria-associated clusters during apoptosis. J. Cell Biol. 2001, 153:1265-1276.
    • (2001) J. Cell Biol. , vol.153 , pp. 1265-1276
    • Nechushtan, A.1    Smith, C.L.2    Lamensdorf, I.3    Yoon, S.H.4    Youle, R.J.5
  • 26
    • 0032493755 scopus 로고    scopus 로고
    • Lipopolysaccharide mediates endothelial apoptosis by a fadd-dependent pathway
    • Choi K.B., Wong F., Harlan J.M., Chaudhary P.M., Hood L., Karsan A. Lipopolysaccharide mediates endothelial apoptosis by a fadd-dependent pathway. J. Biol. Chem. 1998, 273:20185-20188.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20185-20188
    • Choi, K.B.1    Wong, F.2    Harlan, J.M.3    Chaudhary, P.M.4    Hood, L.5    Karsan, A.6
  • 29
    • 26044453495 scopus 로고    scopus 로고
    • Interleukin-10 inhibits lipopolysaccharide-induced survival and extracellular signal-regulated kinase activation in human neutrophils
    • Ward C., Murray J., Clugston A., Dransfield I., Haslett C., Rossi A.G. Interleukin-10 inhibits lipopolysaccharide-induced survival and extracellular signal-regulated kinase activation in human neutrophils. Eur. J. Immunol. 2005, 35:2728-2737.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 2728-2737
    • Ward, C.1    Murray, J.2    Clugston, A.3    Dransfield, I.4    Haslett, C.5    Rossi, A.G.6
  • 30
    • 33947239704 scopus 로고    scopus 로고
    • Tlr4-mediated survival of macrophages is myd88 dependent and requires TNF-alpha autocrine signalling
    • Lombardo E., Alvarez-Barrientos A., Maroto B., Bosca L., Knaus U.G. Tlr4-mediated survival of macrophages is myd88 dependent and requires TNF-alpha autocrine signalling. J. Immunol. 2007, 178:3731-3739.
    • (2007) J. Immunol. , vol.178 , pp. 3731-3739
    • Lombardo, E.1    Alvarez-Barrientos, A.2    Maroto, B.3    Bosca, L.4    Knaus, U.G.5
  • 32
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 2004, 4:499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 34
    • 0035154914 scopus 로고    scopus 로고
    • MAP kinase activation in macrophages
    • Rao K.M. MAP kinase activation in macrophages. J. Leukoc. Biol. 2001, 69:3-10.
    • (2001) J. Leukoc. Biol. , vol.69 , pp. 3-10
    • Rao, K.M.1
  • 35
    • 84863987492 scopus 로고    scopus 로고
    • TLR2 and TLR4 Activate p38 MAPK and JNK during endurance exercise in skeletal muscle
    • Feb 9 (Epub ahead of print).
    • H.Z. Foncea, J.M. Raymackers, L. Deldicque, P. Renard, M. Francaux, TLR2 and TLR4 Activate p38 MAPK and JNK during endurance exercise in skeletal muscle. Med. Sci. Sports Exerc. 2012 Feb 9 (Epub ahead of print).
    • (2012) Med. Sci. Sports Exerc.
    • Foncea, H.Z.1    Raymackers, J.M.2    Deldicque, L.3    Renard, P.4    Francaux, M.5
  • 36
    • 84856367344 scopus 로고    scopus 로고
    • GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-κB
    • Guo F., Zhou Z., Dou Y., Tang J., Gao C., Huan J. GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-κB. Cytokine 2012, 57:417-428.
    • (2012) Cytokine , vol.57 , pp. 417-428
    • Guo, F.1    Zhou, Z.2    Dou, Y.3    Tang, J.4    Gao, C.5    Huan, J.6
  • 37
    • 0034910465 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen activated protein kinase increases lipopolysaccharide induced inhibition of apoptosis in neutrophils by activating extracellular signal-regulated kinase
    • Sheth K., Friel J., Nolan B., Bankey P. Inhibition of p38 mitogen activated protein kinase increases lipopolysaccharide induced inhibition of apoptosis in neutrophils by activating extracellular signal-regulated kinase. Surgery 2001, 130:242-248.
    • (2001) Surgery , vol.130 , pp. 242-248
    • Sheth, K.1    Friel, J.2    Nolan, B.3    Bankey, P.4
  • 39
    • 0033162780 scopus 로고    scopus 로고
    • Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury
    • Donnahoo K.K., Shames B.D., Harken A.H., Meldrum D.R. Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury. J. Urol. 1999, 162:196-203.
    • (1999) J. Urol. , vol.162 , pp. 196-203
    • Donnahoo, K.K.1    Shames, B.D.2    Harken, A.H.3    Meldrum, D.R.4
  • 41
    • 0842304532 scopus 로고    scopus 로고
    • Innate cellular response to virus particle entry requires irf3 but not virus replication
    • Collins S.E., Noyce R.S., Mossman K.L. Innate cellular response to virus particle entry requires irf3 but not virus replication. J. Virol. 2004, 78:1706-1717.
    • (2004) J. Virol. , vol.78 , pp. 1706-1717
    • Collins, S.E.1    Noyce, R.S.2    Mossman, K.L.3
  • 43
    • 44449165650 scopus 로고    scopus 로고
    • Deletion of myd88 markedly attenuates sepsis-induced t and b lymphocyte apoptosis but worsens survival
    • Peck-Palmer O.M., Unsinger J., Chang K.C., Davis C.G., McDunn J.E., Hotchkiss R.S. Deletion of myd88 markedly attenuates sepsis-induced t and b lymphocyte apoptosis but worsens survival. J. Leukoc. Biol. 2008, 83:1009-1018.
    • (2008) J. Leukoc. Biol. , vol.83 , pp. 1009-1018
    • Peck-Palmer, O.M.1    Unsinger, J.2    Chang, K.C.3    Davis, C.G.4    McDunn, J.E.5    Hotchkiss, R.S.6
  • 44
    • 33645987645 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • D'Cruz D.P. Systemic lupus erythematosus. BMJ 2006, 332:890-894.
    • (2006) BMJ , vol.332 , pp. 890-894
    • D'Cruz, D.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.