Simultaneous determination of global DNA methylation and hydroxymethylation levels by hydrophilic interaction liquid chromatography-tandem mass spectrometry

Journal of Biomolecular Screening

Volumn 17, Issue 7, 2012, Pages 877-884

  Zhang, Liangtao ^a   Zhang, Lijian ^a   Zhou, Keyuan ^a   Ye, Xiaoxia ^a   Zhang, Junjie ^a   Xie, Aimei ^a   Chen, Liyu ^a   Kang, Jing X ^b   Cai, Chun ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

DNA hydroxymethylation; DNA methylation; hydrophilic interaction liquid chromatography MS MS

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; CHLOROFORM; CYTOSINE; DNA; ETHYLENE; FORMIC ACID; PHENOL;

ACCURACY; ANIMAL TISSUE; ARTICLE; DNA EXTRACTION; DNA METHYLATION; HYBRID; HYDROLYSIS; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LINEAR SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

5-METHYLCYTOSINE; ANIMALS; CHROMATOGRAPHY, LIQUID; CYTOSINE; DNA; DNA METHYLATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIMIT OF DETECTION; TANDEM MASS SPECTROMETRY;

MAMMALIA;

EID: 84863825679     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112447946     Document Type: Article

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