Default-mode network changes in preclinical Huntington's disease

Experimental Neurology

Volumn 237, Issue 1, 2012, Pages 191-198

  Wolf, Robert Christian ^a,c   Sambataro, Fabio ^b   Vasic, Nenad ^c   Wolf, Nadine Donata ^d   Thomann, Philipp Arthur ^a   Saft, Carsten ^e   Landwehrmeyer, G Bernhard ^c   Orth, Michael ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^c UNIVERSITY OF ULM   (Germany)

^d CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^e ST JOSEF HOSPITAL   (Germany)

Author keywords

Attention; Default mode network; Functional magnetic resonance imaging; Huntington's disease; Prefrontal cortex

Indexed keywords

VENLAFAXINE;

ADULT; ARTICLE; CAG REPEAT; CLINICAL ARTICLE; CONTROLLED STUDY; DEFAULT MODE NETWORK; FEMALE; FUNCTIONAL ASSESSMENT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL STATUS; HANDEDNESS; HUMAN; HUNTINGTON CHOREA; MALE; NERVE CELL NETWORK; NEUROIMAGING; POSTERIOR CINGULATE; POSTERIOR PARIETAL CORTEX; PREFRONTAL CORTEX; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL;

ADULT; BEHAVIORAL SYMPTOMS; BRAIN MAPPING; EARLY DIAGNOSIS; FEMALE; HUMANS; HUNTINGTON DISEASE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE NET; NEUROPSYCHOLOGICAL TESTS;

EID: 84863822677     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.06.014     Document Type: Article

References (68)

1. Andrews-Hanna J.R., Reidler J.S., Sepulcre J., Poulin R., Buckner R.L. Functional-anatomic fractionation of the brain's default network. Neuron 2010, 65:550-562.
2. Aylward E.H. Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease. Brain Res. Bull. 2007, 72:152-158.
3. Beck A.T., Ward C.H., Mendelson M., Mock J., Erbaugh J. An inventory for measuring depression. Arch. Gen. Psychiatry 1961, 4:561-571.
4. Bohanna I., Georgiou-Karistianis N., Hannan A.J., Egan G.F. Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease. Brain Res. Rev. 2008, 58:209-225.
5. Broyd S.J., Demanuele C., Debener S., Helps S.K., James C.J., Sonuga-Barke E.J. Default-mode brain dysfunction in mental disorders: a systematic review. Neurosci. Biobehav. Rev. 2008, 33(3):279-296.
6. Buckner R.L., Andrews-Hanna J.R., Schacter D.L. The brain's default network: anatomy, function, and relevance to disease. Ann. N. Y. Acad. Sci. 2008, 1124:1-38.
7. Calhoun V.D., Adali T., Pearlson G.D., Pekar J.J. A method for making group inferences from functional MRI data using independent component analysis. Hum. Brain Mapp. 2001, 14:140-151.
8. Calhoun V.D., Adali T., Pekar J.J. A method for comparing group fMRI data using independent component analysis: application to visual, motor and visuomotor tasks. Magn. Reson. Imaging 2004, 22:1181-1191.
9. Correa N., Adali T., Yi-Ou L., Calhoun V.D. Comparison of blind source separation algorithms for FMRI using a new Matlab toolbox: GIFT. Proc. IEEE Int. Conf. Acoust. Speech Signal Process. 2005, 5:401-404.
10. Damoiseaux J.S., Rombouts S.A., Barkhof F., Scheltens P., Stam C.J., Smith S.M., Beckmann C.F. Consistent resting-state networks across healthy subjects. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:13848-13853.
11. Damoiseaux J.S., Beckmann C.F., Arigita E.J., Barkhof F., Scheltens P., Stam C.J., Smith S.M., Rombouts S.A. Reduced resting-state brain activity in the "default network" in normal aging. Cereb. Cortex 2007, 18(8):1856-1864.
12. Delaveau P., Salgado-Pineda P., Fossati P., Witjas T., Azulay J.P., Blin O. Dopaminergic modulation of the default mode network in Parkinson's disease. Eur. Neuropsychopharmacol. 2011, 20:784-792.
13. Esposito F., Bertolino A., Scarabino T., Latorre V., Blasi G., Popolizio T., Tedeschi G., Cirillo S., Goebel R., Di Salle F. Independent component model of the default-mode brain function: assessing the impact of active thinking. Brain Res. Bull. 2006, 70:263-269.
14. Feigin A., Tang C., Ma Y., Mattis P., Zgaljardic D., Guttman M., Paulsen J.S., Dhawan V., Eidelberg D. Thalamic metabolism and symptom onset in preclinical Huntington's disease. Brain 2007, 130:2858-2867.
15. Fox M.D., Greicius M. Clinical applications of resting state functional connectivity. Front. Syst. Neurosci. 2010, 4:19.
16. Fox M.D., Snyder A.Z., Vincent J.L., Corbetta M., Van Essen D.C., Raichle M.E. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:9673-9678.
17. Gomez-Anson B., Alegret M., Munoz E., Monte G.C., Alayrach E., Sanchez A., Boada M., Tolosa E. Prefrontal cortex volume reduction on MRI in preclinical Huntington's disease relates to visuomotor performance and CAG number. Parkinsonism Relat. Disord. 2009, 15:213-219.
18. Gusnard D.A., Raichle M.E. Searching for a baseline: functional imaging and the resting human brain. Nat. Rev. Neurosci. 2001, 2:685-692.
19. Gusnard D.A., Akbudak E., Shulman G.L., Raichle M.E. Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:4259-4264.
20. Hafkemeijer A., van der Grond J., Rombouts S.A. Imaging the default mode network in aging and dementia. Biochim. Biophys. Acta 2012, 1822(3):431-441.
21. Harris G.J., Codori A.M., Lewis R.F., Schmidt E., Bedi A., Brandt J. Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease. Brain 1999, 122(Pt 9):1667-1678.
22. Henley S.M., Wild E.J., Hobbs N.Z., Scahill R.I., Ridgway G.R., Macmanus D.G., Barker R.A., Fox N.C., Tabrizi S.J. Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease. J. Neurol. 2009, 256:203-212.
23. Hennenlotter A., Schroeder U., Erhard P., Haslinger B., Stahl R., Weindl A., von Einsiedel H.G., Lange K.W., Ceballos-Baumann A.O. Neural correlates associated with impaired disgust processing in pre-symptomatic Huntington's disease. Brain 2004, 127:1446-1453.
24. Himberg J., Hyvarinen A., Esposito F. Validating the independent components of neuroimaging time series via clustering and visualization. NeuroImage 2004, 22:1214-1222.
25. Huntington-Study-Group Unified Huntington's Disease Rating Scale: reliability and consistency. Movement Disorders 1996, 11:136-142.
26. Jafri M.J., Pearlson G.D., Stevens M., Calhoun V.D. A method for functional network connectivity among spatially independent resting-state components in schizophrenia. NeuroImage 2008, 39:1666-1681.
27. Kelly A.M., Uddin L.Q., Biswal B., Castellanos F.X., Milham M.P. Competition between functional brain networks mediates behavioral variability. NeuroImage 2008, 39:527-537.
28. Kloppel S., Draganski B., Siebner H.R., Tabrizi S.J., Weiller C., Frackowiak R.S. Functional compensation of motor function in pre-symptomatic Huntington's disease. Brain 2009, 132:1624-1632.
29. Kloppel S., Henley S.M., Hobbs N.Z., Wolf R.C., Kassubek J., Tabrizi S.J., Frackowiak R.S. Magnetic resonance imaging of Huntington's disease: preparing for clinical trials. Neuroscience 2009, 164:205-219.
30. Krajcovicova L., Mikl M., Marecek R., Rektorova I. The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent. J. Neural Transm. 2010, 119(4):443-454.
31. Langbehn D.R., Brinkman R.R., Falush D., Paulsen J.S., Hayden M.R., Group, I.H.s.D.C. A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clin. Genet. 2004, 65:267-277.
32. Lawrence A.D., Weeks R.A., Brooks D.J., et al. The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease. Brain 1998, 1343-1355.
33. Li Y.O., Adali T., Calhoun V.D. Estimating the number of independent components for functional magnetic resonance imaging data. Hum. Brain Mapp. 2007, 28:1251-1266.
34. Ligot N., Krystkowiak P., Simonin C., Goldman S., Peigneux P., Van Naemen J., Monclus M., Lacroix S.F., Devos D., Dujardin K., Delmaire C., Bardinet E., Delval A., Delliaux M., Defebvre L., Yelnik J., Blond S., Destee A., De Tiege X. External globus pallidus stimulation modulates brain connectivity in Huntington's disease. J. Cereb. Blood Flow Metab. 2011, 31:41-46.
35. Meindl T., Teipel S., Elmouden R., Mueller S., Koch W., Dietrich O., Coates U., Reiser M., Glaser C. Test-retest reproducibility of the default-mode network in healthy individuals. Hum. Brain Mapp. 2010, 31:237-246.
36. Oldfield R.C. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971, 9:97-113.
37. Paulsen J.S. Functional imaging in Huntington's disease. Exp. Neurol. 2009, 216:272-277.
38. Paulsen J.S., Magnotta V.A., Mikos A.E., Paulson H.L., Penziner E., Andreasen N.C., Nopoulos P.C. Brain structure in preclinical Huntington's disease. Biol. Psychiatry 2006, 59:57-63.
39. Pavese N., Politis M., Tai Y.F., Barker R.A., Tabrizi S.J., Mason S.L., Brooks D.J., Piccini P. Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers. Neurobiol. Dis. 2010, 37:356-361.
40. Penney J.B., Vonsattel J.P., MacDonald M.E., Gusella J.F., Myers R.H. CAG repeat number governs the development rate of pathology in Huntington's disease. Ann. Neurol. 1997, 41:689-692.
41. Perin B., Godefroy O., Fall S., de Marco G. Alertness in young healthy subjects: an fMRI study of brain region interactivity enhanced by a warning signal. Brain Cogn. 2010, 72:271-281.
42. Posner M.I. Measuring alertness. Ann. N. Y. Acad. Sci. 2008, 1129:193-199.
43. Qi Z., Wu X., Wang Z., Zhang N., Dong H., Yao L., Li K. Impairment and compensation coexist in amnestic MCI default mode network. NeuroImage 2010, 50:48-55.
44. Raichle M.E., MacLeod A.M., Snyder A.Z., Powers W.J., Gusnard D.A., Shulman G.L. A default mode of brain function. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:676-682.
45. Rajah M.N., D'Esposito M. Region-specific changes in prefrontal function with age: a review of PET and fMRI studies on working and episodic memory. Brain 2005, 128(Pt 9):1964-1983.
46. Reading S.A., Dziorny A.C., Peroutka L.A., Schreiber M., Gourley L.M., Yallapragada V., Rosenblatt A., Margolis R.L., Pekar J.J., Pearlson G.D., Aylward E., Brandt J., Bassett S.S., Ross C.A. Functional brain changes in presymptomatic Huntington's disease. Ann. Neurol. 2004, 55:879-883.
47. Rosas H.D., Hevelone N.D., Zaleta A.K., Greve D.N., Salat D.H., Fischl B. Regional cortical thinning in preclinical Huntington disease and its relationship to cognition. Neurology 2005, 65:745-747.
48. Ross C.A., Tabrizi S.J. Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol. 2011, 10:83-98.
49. Ruocco H.H., Bonilha L., Li M.L., Lopes-Cendes I., Cendes F. Longitudinal analysis of regional gray matter loss in Huntington disease: effects of the length of the expanded CAG repeat. J. Neurol. Neurosurg. Psychiatry 2007, 79(2):130-135.
50. Saft C., Schuttke A., Beste C., Andrich J., Heindel W., Pfleiderer B. fMRI reveals altered auditory processing in manifest and premanifest Huntington's disease. Neuropsychologia 2008, 46:1279-1289.
51. Sambataro F., Murty V.P., Callicott J.H., Tan H.Y., Das S., Weinberger D.R., Mattay V.S. Age-related alterations in default mode network: impact on working memory performance. Neurobiol. Aging 2008, 31(5):839-852.
52. Sambataro F., Blasi G., Fazio L., Caforio G., Taurisano P., Romano R., Di Giorgio A., Gelao B., Lo Bianco L., Papazacharias A., Popolizio T., Nardini M., Bertolino A. Treatment with olanzapine is associated with modulation of the default mode network in patients with Schizophrenia. Neuropsychopharmacology 2010, 35:904-912.
53. Smith S.M., Fox P.T., Miller K.L., Glahn D.C., Fox P.M., Mackay C.E., Filippini N., Watkins K.E., Toro R., Laird A.R., Beckmann C.F. Correspondence of the brain's functional architecture during activation and rest. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:13040-13045.
54. Sturm W., Willmes K. On the functional neuroanatomy of intrinsic and phasic alertness. NeuroImage 2001, 14:S76-S84.
55. Tabrizi S.J., Langbehn D.R., Leavitt B.R., Roos R.A., Durr A., Craufurd D., Kennard C., Hicks S.L., Fox N.C., Scahill R.I., Borowsky B., Tobin A.J., Rosas H.D., Johnson H., Reilmann R., Landwehrmeyer B., Stout J.C. Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet Neurol. 2009, 8:791-801.
56. Tabrizi S.J., Reilmann R., Roos R.A., Durr A., Leavitt B., Owen G., Jones R., Johnson H., Craufurd D., Hicks S.L., Kennard C., Landwehrmeyer B., Stout J.C., Borowsky B., Scahill R.I., Frost C., Langbehn D.R. Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data. Lancet Neurol. 2012, 11:42-53.
57. Uddin L.Q., Clare Kelly A.M., Biswal B., Margulies D.S., Shezad Z., Shaw D., Ghaffari M., Rotrosen J., Adler L.A., Castellanos F.X., Milham M.P. Network homogeneity reveals decreased integrity of default-mode network in ADHD. J. Neurosci. Methods 2008, 169:249-254.
58. Uddin L.Q., Kelly A.M., Biswal B.B., Xavier Castellanos F., Milham M.P. Functional connectivity of default mode network components: correlation, anticorrelation, and causality. Hum. Brain Mapp. 2009, 30:625-637.
59. van den Heuvel M.P., Hulshoff Pol H.E. Exploring the brain network: a review on resting-state fMRI functional connectivity. Eur. Neuropsychopharmacol. 2010, 20:519-534.
60. van Eimeren T., Monchi O., Ballanger B., Strafella A.P. Dysfunction of the default mode network in Parkinson disease: a functional magnetic resonance imaging study. Arch. Neurol. 2009, 66:877-883.
61. Vonsattel J.P., Myers R.H., Stevens T.J. Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 1985, 44:559-577.
62. Weir D.W., Sturrock A., Leavitt B.R. Development of biomarkers for Huntington's disease. Lancet Neurol. 2011, 10:573-590.
63. Wolf R.C., Vasic N., Schonfeldt-Lecuona C., Landwehrmeyer G.B., Ecker D. Dorsolateral prefrontal cortex dysfunction in presymptomatic Huntington's disease: evidence from event-related fMRI. Brain 2007, 130:2845-2857.
64. Wolf R.C., Vasic N., Sambataro F., Höse A., Frasch K., Schmidt M., Walter H. Temporally anticorrelated brain networks during working memory performance reveal prefrontal and hippocampal dysconnectivity in patients with schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2009, 33:1464-1473.
65. Wolf, R.C., Grön, G., Sambataro, F., Vasic, N., Wolf, N.D., Thomann, P.A., Saft, C., Landwehrmeyer, B., Orth, M., in press. Brain activation and functional connectivity in premanifest Huntington's disease during states of intrinsic and phasic alertness. Hum. Brain Mapp.
66. Worsley K.J., Cao J., Paus T., Petrides M., Evans A.C. Applications of random field theory to functional connectivity. Hum. Brain Mapp. 1998, 6:364-367.
67. Zimbelman J.L., Paulsen J.S., Mikos A.E., Reynolds N.C., Hoffman R.G., Rao S.M. fMRI detection of early neural dysfunction in preclinical Huntington's disease. J. Int. Neuropsychol. Soc. 2007, 13:758-769.
68. Zimmermann P., Fimm B. Tests of Attentional Performance; [Testbatterie zur Aufmerksamkeitsprüfung, TAP] 1994, Psytest, Herzogenrath.