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Volumn 122, Issue 9, 1999, Pages 1667-1678

Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease

Author keywords

Gene testing; Huntington's disease; MRI; Pre symptomatic; Single photon emission computed tomography (SPECT)

Indexed keywords

ADULT; AGED; ARTICLE; BASAL GANGLION; BRAIN BLOOD FLOW; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HIGH RISK PATIENT; HUMAN; HUNTINGTON CHOREA; MALE; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIORITY JOURNAL; PUTAMEN; REGRESSION ANALYSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

EID: 0032860404     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/122.9.1667     Document Type: Article
Times cited : (123)

References (53)
  • 1
    • 0032065590 scopus 로고    scopus 로고
    • ACMG/ASHG statement: Laboratory guidelines for Huntington disease genetic testing
    • ACMG/ASHG (The American College of Medical Genetics/ American Society of Human Genetics) Huntington's Disease Genetic Testing Working Group. ACMG/ASHG statement: laboratory guidelines for Huntington disease genetic testing. Am J Hum Genet 1998; 62: 1243-7.
    • (1998) Am J Hum Genet , vol.62 , pp. 1243-1247
  • 2
    • 0022930826 scopus 로고
    • Parallel organization of functionally segregated circuits linking basal ganglia and cortex
    • Review
    • Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. [Review]. Annu Rev Neurosci 1986; 9: 357-81.
    • (1986) Annu Rev Neurosci , vol.9 , pp. 357-381
    • Alexander, G.E.1    DeLong, M.R.2    Strick, P.L.3
  • 4
    • 0028365786 scopus 로고
    • Reduced basal ganglia volume associated with the gene for Huntington's disease in asymptomatic at-risk persons
    • Aylward EH, Brandt J, Codori AM, Mangus RS, Barta PE, Harris GJ. Reduced basal ganglia volume associated with the gene for Huntington's disease in asymptomatic at-risk persons. Neurology 1994; 44: 823-8.
    • (1994) Neurology , vol.44 , pp. 823-828
    • Aylward, E.H.1    Brandt, J.2    Codori, A.M.3    Mangus, R.S.4    Barta, P.E.5    Harris, G.J.6
  • 6
    • 0024411737 scopus 로고
    • Clinical-pathologic correlation in Huntington's disease: A neuropsychological and computed tomography study
    • Bamford KA, Caine ED, Kido DK, Plassche WM, Shoulson I. Clinical-pathologic correlation in Huntington's disease: a neuropsychological and computed tomography study. Neurology 1989; 39: 796-801.
    • (1989) Neurology , vol.39 , pp. 796-801
    • Bamford, K.A.1    Caine, E.D.2    Kido, D.K.3    Plassche, W.M.4    Shoulson, I.5
  • 7
    • 0018145378 scopus 로고
    • Bicaudate index in computerized tomography of huntington disease and cerebral atrophy
    • Barr AN, Heinze WJ, Dobben GD, Valvassori GE, Sugar O. Bicaudate index in computerized tomography of Huntington disease and cerebral atrophy. Neurology 1978; 28: 1196-200.
    • (1978) Neurology , vol.28 , pp. 1196-1200
    • Barr, A.N.1    Heinze, W.J.2    Dobben, G.D.3    Valvassori, G.E.4    Sugar, O.5
  • 9
    • 0023884580 scopus 로고
    • Positron emission tomographic scan investigations of Huntington's disease: Cerebral metabolic correlates of cognitive function
    • Berent S, Giordani B, Lehtinen S, Markel D, Penney JB, Buchtel HA, et al. Positron emission tomographic scan investigations of Huntington's disease: cerebral metabolic correlates of cognitive function. Ann Neurol 1988; 23: 541-6.
    • (1988) Ann Neurol , vol.23 , pp. 541-546
    • Berent, S.1    Giordani, B.2    Lehtinen, S.3    Markel, D.4    Penney, J.B.5    Buchtel, H.A.6
  • 10
    • 0001670657 scopus 로고
    • Huntington's chorea: Historical, clinical and laboratory synopsis
    • Vinken PJ, Bruyn GW, editors. Amsterdam: North-Holland
    • Bruyn GW. Huntington's chorea: historical, clinical and laboratory synopsis. In: Vinken PJ, Bruyn GW, editors. Handbook of clinical neurology, Vol. 6. Amsterdam: North-Holland; 1968. p. 298-378.
    • (1968) Handbook of Clinical Neurology , vol.6 , pp. 298-378
    • Bruyn, G.W.1
  • 11
    • 0022589291 scopus 로고
    • Atrophy of corpus striatum in normal male at risk of Huntington's chorea
    • Carrasco LH, Mukherji CS. Atrophy of corpus striatum in normal male at risk of Huntington's chorea [letter]. Lancet 1986; 1: 1388-9.
    • (1986) Lancet , vol.1 , pp. 1388-1389
    • Carrasco, L.H.1    Mukherji, C.S.2
  • 12
    • 0031649082 scopus 로고    scopus 로고
    • Cerebral blood flow velocity decreases during cognitive stimulation in Huntington's disease
    • Deckel AW, Cohen D, Duckrow R. Cerebral blood flow velocity decreases during cognitive stimulation in Huntington's disease. Neurology 1998; 51: 1576-83.
    • (1998) Neurology , vol.51 , pp. 1576-1583
    • Deckel, A.W.1    Cohen, D.2    Duckrow, R.3
  • 13
    • 0343760094 scopus 로고
    • Anatomical and functional aspects of basal ganglia-thalamocortical circuits
    • Franks AJ, Ironside JW, Mindham RH, Smith RJ, Spokes EG, Winslow W, editors. Manchester: Manchester University Press
    • DeLong MR, Alexander GE, Miller WC, Crutcher MD. Anatomical and functional aspects of basal ganglia-thalamocortical circuits. In: Franks AJ, Ironside JW, Mindham RH, Smith RJ, Spokes EG, Winslow W, editors. Function and dysfunction in the basal ganglia. Manchester: Manchester University Press; 1990. p. 3-32.
    • (1990) Function and Dysfunction in the Basal Ganglia , pp. 3-32
    • DeLong, M.R.1    Alexander, G.E.2    Miller, W.C.3    Crutcher, M.D.4
  • 15
    • 0016823810 scopus 로고
    • 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-98.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 17
    • 0021187087 scopus 로고
    • Reduced striatal glucose consumption and prolonged reaction time are early features in Huntington's disease
    • Garnett ES, Firnau G, Nahmias C, Carbotte R, Bartolucci G. Reduced striatal glucose consumption and prolonged reaction time are early features in Huntington's disease. J Neurol Sci 1984; 65: 231-7.
    • (1984) J Neurol Sci , vol.65 , pp. 231-237
    • Garnett, E.S.1    Firnau, G.2    Nahmias, C.3    Carbotte, R.4    Bartolucci, G.5
  • 18
    • 0025009430 scopus 로고
    • A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's disease
    • Grafton ST, Mazziotta JC, Pahl JJ, St. George-Hyslop P, Haines JL, Gusella J, et al. A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's disease. Ann Neurol 1990; 28: 614-21.
    • (1990) Ann Neurol , vol.28 , pp. 614-621
    • Grafton, S.T.1    Mazziotta, J.C.2    Pahl, J.J.3    St. George-Hyslop, P.4    Haines, J.L.5    Gusella, J.6
  • 19
    • 0026475301 scopus 로고
    • Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease
    • Grafton ST, Mazziotta JC, Pahl JJ, St. George-Hyslop P, Haines JL, Gusella J, et al. Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease. Arch Neurol 1992; 49: 1161-7.
    • (1992) Arch Neurol , vol.49 , pp. 1161-1167
    • Grafton, S.T.1    Mazziotta, J.C.2    Pahl, J.J.3    St. George-Hyslop, P.4    Haines, J.L.5    Gusella, J.6
  • 20
    • 0027309105 scopus 로고
    • MRI-guided region of interest placement on emission computed tomograms
    • Harris GJ, Pearlson GD. MRI-guided region of interest placement on emission computed tomograms. Psychiatry Res 1993; 50: 57-63.
    • (1993) Psychiatry Res , vol.50 , pp. 57-63
    • Harris, G.J.1    Pearlson, G.D.2
  • 21
    • 0026584454 scopus 로고
    • Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington's disease
    • Harris GJ, Pearlson GD, Peyser CE, Aylward EH, Roberts J, Barta PE, et al. Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington's disease. Ann Neurol 1992; 31: 69-75.
    • (1992) Ann Neurol , vol.31 , pp. 69-75
    • Harris, G.J.1    Pearlson, G.D.2    Peyser, C.E.3    Aylward, E.H.4    Roberts, J.5    Barta, P.E.6
  • 22
    • 0029987151 scopus 로고    scopus 로고
    • Single photon emission computed tomographic blood flow and magnetic resonance volume imaging of basal ganglia in Huntington's disease
    • Harris GJ, Aylward EH, Peyser CE, Pearlson GD, Brandt J, Roberts-Twillie JV, et al. Single photon emission computed tomographic blood flow and magnetic resonance volume imaging of basal ganglia in Huntington's disease. Arch Neurol 1996; 53: 316-24.
    • (1996) Arch Neurol , vol.53 , pp. 316-324
    • Harris, G.J.1    Aylward, E.H.2    Peyser, C.E.3    Pearlson, G.D.4    Brandt, J.5    Roberts-Twillie, J.V.6
  • 25
    • 0023250460 scopus 로고
    • The combined use of positron emission tomography and DNA polymorphisms for preclinical detection of Huntington's disease
    • Hayden MR, Hewitt J, Stoessl AJ, Clark C, Ammann W, Martin WR. The combined use of positron emission tomography and DNA polymorphisms for preclinical detection of Huntington's disease. Neurology 1987; 37: 1441-7.
    • (1987) Neurology , vol.37 , pp. 1441-1447
    • Hayden, M.R.1    Hewitt, J.2    Stoessl, A.J.3    Clark, C.4    Ammann, W.5    Martin, W.R.6
  • 26
    • 0028799793 scopus 로고
    • Early loss of neostriatal strisome neurons in Huntington's disease
    • Hedreen JC, Folstein SE. Early loss of neostriatal strisome neurons in Huntington's disease. J Neuropathol Exp Neurol 1995; 54: 105-20.
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 105-120
    • Hedreen, J.C.1    Folstein, S.E.2
  • 27
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes [see comments]. Cell 1993; 72: 971-83. Comment in: Cell 1993; 72: 817-8.
    • (1993) Cell , vol.72 , pp. 971-983
  • 28
    • 0027480255 scopus 로고
    • Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes [see comments]. Cell 1993; 72: 971-83. Comment in: Cell 1993; 72: 817-8.
    • (1993) Cell , vol.72 , pp. 817-818
  • 29
    • 0027171135 scopus 로고
    • Iodine-123-IBZM dopamine D2 receptor and technetium-99m-HMPAO brain perfusion SPECT in the evaluation of patients with and subjects at risk for Huntington's disease
    • Ichise M, Toyama H, Fornazzari L, Ballinger JR, Kirsh JC. Iodine-123-IBZM dopamine D2 receptor and technetium-99m-HMPAO brain perfusion SPECT in the evaluation of patients with and subjects at risk for Huntington's disease. J Nucl Med 1993; 34: 1274-81.
    • (1993) J Nucl Med , vol.34 , pp. 1274-1281
    • Ichise, M.1    Toyama, H.2    Fornazzari, L.3    Ballinger, J.R.4    Kirsh, J.C.5
  • 30
    • 0025971903 scopus 로고
    • Cerebral structure on MRI, Part II: Specific changes in Alzheimer's and Huntington's diseases
    • Jernigan TL, Salmon DP, Butters N, Hesselink JR. Cerebral structure on MRI, Part II: specific changes in Alzheimer's and Huntington's diseases. Biol Psychiatry 1991; 29: 68-81.
    • (1991) Biol Psychiatry , vol.29 , pp. 68-81
    • Jernigan, T.L.1    Salmon, D.P.2    Butters, N.3    Hesselink, J.R.4
  • 31
    • 0019991784 scopus 로고
    • Cerebral metabolism and atrophy in Huntington's disease determined by 18-FDG and computed tomographic scan
    • Kuhl DE, Phelps ME, Markham CH, Metter EJ, Riege WH, Winter J. Cerebral metabolism and atrophy in Huntington's disease determined by 18-FDG and computed tomographic scan. Ann Neurol 1982; 12: 425-34.
    • (1982) Ann Neurol , vol.12 , pp. 425-434
    • Kuhl, D.E.1    Phelps, M.E.2    Markham, C.H.3    Metter, E.J.4    Riege, W.H.5    Winter, J.6
  • 32
    • 0024386255 scopus 로고
    • Cerebral glucose consumption measured by PET in patients with and without psychiatric symptoms of Huntington's disease
    • Kuwert T, Lange HW, Langen KJ, Herzog H, Aulich A, Feinendegen LE. Cerebral glucose consumption measured by PET in patients with and without psychiatric symptoms of Huntington's disease. Psychiatry Res 1989; 29: 361-2.
    • (1989) Psychiatry Res , vol.29 , pp. 361-362
    • Kuwert, T.1    Lange, H.W.2    Langen, K.J.3    Herzog, H.4    Aulich, A.5    Feinendegen, L.E.6
  • 33
    • 0025153344 scopus 로고
    • Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease
    • Kuwert T, Lange HW, Langen KJ, Herzog H, Aulich A, Feinendegen LE. Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease. Brain 1990; 113: 1405-23.
    • (1990) Brain , vol.113 , pp. 1405-1423
    • Kuwert, T.1    Lange, H.W.2    Langen, K.J.3    Herzog, H.4    Aulich, A.5    Feinendegen, L.E.6
  • 34
    • 0027441163 scopus 로고
    • Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease
    • Kuwert T, Lange HW, Boecker H, Titz H, Herzog H, Aulich A, et al. Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease [see comments]. J Neurol 1993a; 241: 31-6, Comment in: J Neurol 1995; 242: 112-4.
    • (1993) J Neurol , vol.241 , pp. 31-36
    • Kuwert, T.1    Lange, H.W.2    Boecker, H.3    Titz, H.4    Herzog, H.5    Aulich, A.6
  • 35
    • 0028831893 scopus 로고
    • Kuwert T, Lange HW, Boecker H, Titz H, Herzog H, Aulich A, et al. Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease [see comments]. J Neurol 1993a; 241: 31-6, Comment in: J Neurol 1995; 242: 112-4.
    • (1995) J Neurol , vol.242 , pp. 112-114
  • 36
    • 0027388933 scopus 로고
    • Comparison of somatosensory evoked potentials with striatal glucose consumption measured by positron emission tomography in the early diagnosis of Huntington's disease
    • Kuwert T, Noth J, Scholz D, Schwarz M, Lange HW, Topper R, et al. Comparison of somatosensory evoked potentials with striatal glucose consumption measured by positron emission tomography in the early diagnosis of Huntington's disease. Mov Disord 1993b; 8: 98-106.
    • (1993) Mov Disord , vol.8 , pp. 98-106
    • Kuwert, T.1    Noth, J.2    Scholz, D.3    Schwarz, M.4    Lange, H.W.5    Topper, R.6
  • 37
    • 0029186447 scopus 로고
    • A modality-independent approach to spatial normalization of tomographic images of the human brain
    • Lancaster JL, Glass TG, Lankipalli BR, Downs H, Mayberg H, Fox PT. A modality-independent approach to spatial normalization of tomographic images of the human brain. Hum Brain Mapp 1995; 3: 209-23.
    • (1995) Hum Brain Mapp , vol.3 , pp. 209-223
    • Lancaster, J.L.1    Glass, T.G.2    Lankipalli, B.R.3    Downs, H.4    Mayberg, H.5    Fox, P.T.6
  • 40
    • 0023147905 scopus 로고
    • Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease
    • Mazziotta JC, Phelps ME, Pahl JJ, Huang SC, Baxter LR, Riege WH, et al. Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease. N Engl J Med 1987b; 316: 357-62.
    • (1987) N Engl J Med , vol.316 , pp. 357-362
    • Mazziotta, J.C.1    Phelps, M.E.2    Pahl, J.J.3    Huang, S.C.4    Baxter, L.R.5    Riege, W.H.6
  • 41
    • 0019501390 scopus 로고
    • Diagnostic value of CT in patients with Huntington's chorea and their offspring
    • Oepen G, Ostertag C. Diagnostic value of CT in patients with Huntington's chorea and their offspring. J Neurol 1981; 225: 189-96.
    • (1981) J Neurol , vol.225 , pp. 189-196
    • Oepen, G.1    Ostertag, C.2
  • 46
    • 0022883859 scopus 로고
    • Technetium-99m HM-PAO stereoisomers as potential agents for imaging regional cerebral blood flow: Human volunteer studies
    • Sharp PF, Smith FW, Gemmell HG, Lyall D, Evans NT, Gvozdanovic D, et al. Technetium-99m HM-PAO stereoisomers as potential agents for imaging regional cerebral blood flow: human volunteer studies. J Nucl Med 1986; 27: 171-7.
    • (1986) J Nucl Med , vol.27 , pp. 171-177
    • Sharp, P.F.1    Smith, F.W.2    Gemmell, H.G.3    Lyall, D.4    Evans, N.T.5    Gvozdanovic, D.6
  • 52
    • 0022553413 scopus 로고
    • PET scan investigations of Huntington's disease: Cerebral metabolic correlates of neurological features and functional decline
    • Young AB, Penney JB, Starosta-Rubinstein S, Markel DS, Berent S, Giordani B, et al. PET scan investigations of Huntington's disease: cerebral metabolic correlates of neurological features and functional decline. Ann Neurol 1986; 20: 296-303.
    • (1986) Ann Neurol , vol.20 , pp. 296-303
    • Young, A.B.1    Penney, J.B.2    Starosta-Rubinstein, S.3    Markel, D.S.4    Berent, S.5    Giordani, B.6


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