메뉴 건너뛰기




Volumn 7, Issue 7, 2012, Pages

Evidence for a non-catalytic ion-binding site in multiple RNA-dependent RNA polymerases

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CALCIUM ION; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE B; DOUBLE STRANDED RNA; LUTETIUM; MAGNESIUM ION; MANGANESE; METAL ION; RNA DIRECTED RNA POLYMERASE; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; VIRUS RNA;

EID: 84863812509     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040581     Document Type: Article
Times cited : (13)

References (57)
  • 2
    • 0032518398 scopus 로고    scopus 로고
    • Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
    • Doublie S, Tabor S, Long AM, Richardson CC, Ellenberger T, (1998) Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution. Nature 391: 251-258.
    • (1998) Nature , vol.391 , pp. 251-258
    • Doublie, S.1    Tabor, S.2    Long, A.M.3    Richardson, C.C.4    Ellenberger, T.5
  • 3
    • 0035369086 scopus 로고    scopus 로고
    • Structure of the replicating complex of a pol α family DNA polymerase
    • Franklin MC, Wang J, Steitz TA, (2001) Structure of the replicating complex of a pol α family DNA polymerase. Cell 105: 657-667.
    • (2001) Cell , vol.105 , pp. 657-667
    • Franklin, M.C.1    Wang, J.2    Steitz, T.A.3
  • 4
    • 0021984004 scopus 로고
    • Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
    • Ollis DL, Brick P, Hamlin R, Xuong NG, Steitz TA, (1985) Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP. Nature 313: 762-766.
    • (1985) Nature , vol.313 , pp. 762-766
    • Ollis, D.L.1    Brick, P.2    Hamlin, R.3    Xuong, N.G.4    Steitz, T.A.5
  • 5
    • 0028842293 scopus 로고
    • The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1
    • Rodgers DW, Gamblin SJ, Harris BA, Ray S, Culp JS, et al. (1995) The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. Proc Natl Acad Sci USA 92: 1222-1226.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1222-1226
    • Rodgers, D.W.1    Gamblin, S.J.2    Harris, B.A.3    Ray, S.4    Culp, J.S.5
  • 7
    • 0031571638 scopus 로고    scopus 로고
    • Structure of the RNA-dependent RNA polymerase of poliovirus
    • Hansen JL, Long AM, Schultz SC, (1997) Structure of the RNA-dependent RNA polymerase of poliovirus. Structure 5: 1109-1122.
    • (1997) Structure , vol.5 , pp. 1109-1122
    • Hansen, J.L.1    Long, A.M.2    Schultz, S.C.3
  • 8
    • 0037386414 scopus 로고    scopus 로고
    • A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases
    • Bruenn JA, (2003) A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases. Nucleic Acids Res 31: 1821-1829.
    • (2003) Nucleic Acids Res , vol.31 , pp. 1821-1829
    • Bruenn, J.A.1
  • 9
    • 0036434498 scopus 로고    scopus 로고
    • The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage
    • Gorbalenya AE, Pringle FM, Zeddam JL, Luke BT, Cameron CE, et al. (2002) The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage. J Mol Biol 324: 47-62.
    • (2002) J Mol Biol , vol.324 , pp. 47-62
    • Gorbalenya, A.E.1    Pringle, F.M.2    Zeddam, J.L.3    Luke, B.T.4    Cameron, C.E.5
  • 10
    • 0024784519 scopus 로고
    • Identification of four conserved motifs among the RNA-dependent polymerase encoding elements
    • Poch O, Sauvaget I, Delarue M, Tordo N, (1989) Identification of four conserved motifs among the RNA-dependent polymerase encoding elements. EMBO J 8: 3867-3874.
    • (1989) EMBO J , vol.8 , pp. 3867-3874
    • Poch, O.1    Sauvaget, I.2    Delarue, M.3    Tordo, N.4
  • 11
    • 0028881713 scopus 로고
    • Polymerase structures and function: variations on a theme?
    • Joyce CM, Steitz TA, (1995) Polymerase structures and function: variations on a theme? J Bacteriol 177: 6321-6329.
    • (1995) J Bacteriol , vol.177 , pp. 6321-6329
    • Joyce, C.M.1    Steitz, T.A.2
  • 12
    • 0032518374 scopus 로고    scopus 로고
    • A mechanism for all polymerases
    • Steitz TA, (1998) A mechanism for all polymerases. Nature 391: 231-232.
    • (1998) Nature , vol.391 , pp. 231-232
    • Steitz, T.A.1
  • 13
    • 34250643613 scopus 로고    scopus 로고
    • The structure of a birnavirus polymerase reveals a distinct active site topology
    • Pan J, Vakharia VN, Tao YJ, (2007) The structure of a birnavirus polymerase reveals a distinct active site topology. Proc Natl Acad Sci USA 104: 7385-7390.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7385-7390
    • Pan, J.1    Vakharia, V.N.2    Tao, Y.J.3
  • 15
    • 0032876683 scopus 로고    scopus 로고
    • Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
    • Lesburg CA, Cable MB, Ferrari E, Hong Z, Mannarino AF, et al. (1999) Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nat Struct Biol 6: 937-943.
    • (1999) Nat Struct Biol , vol.6 , pp. 937-943
    • Lesburg, C.A.1    Cable, M.B.2    Ferrari, E.3    Hong, Z.4    Mannarino, A.F.5
  • 16
    • 56649105365 scopus 로고    scopus 로고
    • Structural explanation for the role of Mn2+ in the activity of φ6 RNA-dependent RNA polymerase
    • Poranen MM, Salgado PS, Koivunen MR, Wright S, Bamford DH, et al. (2008) Structural explanation for the role of Mn2+ in the activity of φ6 RNA-dependent RNA polymerase. Nucleic Acids Res 36: 6633-6644.
    • (2008) Nucleic Acids Res , vol.36 , pp. 6633-6644
    • Poranen, M.M.1    Salgado, P.S.2    Koivunen, M.R.3    Wright, S.4    Bamford, D.H.5
  • 17
    • 84857865800 scopus 로고    scopus 로고
    • Non-catalytic ions direct the RNA-dependent RNA polymerase of bacterial dsRNA virus φ6 from De Novo initiation to elongation
    • Wright S, Poranen MM, Bamford DH, Stuart DI, Grimes JM, (2012) Non-catalytic ions direct the RNA-dependent RNA polymerase of bacterial dsRNA virus φ6 from De Novo initiation to elongation. J Virol 86: 2837-2849.
    • (2012) J Virol , vol.86 , pp. 2837-2849
    • Wright, S.1    Poranen, M.M.2    Bamford, D.H.3    Stuart, D.I.4    Grimes, J.M.5
  • 18
    • 8744222695 scopus 로고    scopus 로고
    • Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA
    • Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C, Domingo E, et al. (2004) Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. J Biol Chem 279: 47212-47221.
    • (2004) J Biol Chem , vol.279 , pp. 47212-47221
    • Ferrer-Orta, C.1    Arias, A.2    Perez-Luque, R.3    Escarmis, C.4    Domingo, E.5
  • 19
    • 1942501581 scopus 로고    scopus 로고
    • Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft
    • Ng KK, Pendas-Franco N, Rojo J, Boga JA, Machin A, et al. (2004) Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft. J Biol Chem 279: 16638-16645.
    • (2004) J Biol Chem , vol.279 , pp. 16638-16645
    • Ng, K.K.1    Pendas-Franco, N.2    Rojo, J.3    Boga, J.A.4    Machin, A.5
  • 20
    • 0033989278 scopus 로고    scopus 로고
    • De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus
    • Luo G, Hamatake RK, Mathis DM, Racela J, Rigat KL, et al. (2000) De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus. J Virol 74: 851-863.
    • (2000) J Virol , vol.74 , pp. 851-863
    • Luo, G.1    Hamatake, R.K.2    Mathis, D.M.3    Racela, J.4    Rigat, K.L.5
  • 21
    • 0036892593 scopus 로고    scopus 로고
    • Requirements for de novo initiation of RNA synthesis by recombinant flaviviral RNA-dependent RNA polymerases
    • Ranjith-Kumar CT, Gutshall L, Kim MJ, Sarisky RT, Kao CC, (2002) Requirements for de novo initiation of RNA synthesis by recombinant flaviviral RNA-dependent RNA polymerases. J Virol 76: 12526-12536.
    • (2002) J Virol , vol.76 , pp. 12526-12536
    • Ranjith-Kumar, C.T.1    Gutshall, L.2    Kim, M.J.3    Sarisky, R.T.4    Kao, C.C.5
  • 22
    • 0034602836 scopus 로고    scopus 로고
    • Replicase activity of purified recombinant protein P2 of double-stranded RNA bacteriophage φ6
    • Makeyev EV, Bamford DH, (2000) Replicase activity of purified recombinant protein P2 of double-stranded RNA bacteriophage φ6. EMBO J 19: 124-133.
    • (2000) EMBO J , vol.19 , pp. 124-133
    • Makeyev, E.V.1    Bamford, D.H.2
  • 24
    • 0034767585 scopus 로고    scopus 로고
    • Comparison of polymerase subunits from double-stranded RNA bacteriophages
    • Yang H, Makeyev EV, Bamford DH, (2001) Comparison of polymerase subunits from double-stranded RNA bacteriophages. J Virol 75: 11088-11095.
    • (2001) J Virol , vol.75 , pp. 11088-11095
    • Yang, H.1    Makeyev, E.V.2    Bamford, D.H.3
  • 25
    • 0037225770 scopus 로고    scopus 로고
    • Two distinct mechanisms ensure transcriptional polarity in double-stranded RNA bacteriophages
    • Yang H, Makeyev EV, Butcher SJ, Gaidelyte A, Bamford DH, (2003) Two distinct mechanisms ensure transcriptional polarity in double-stranded RNA bacteriophages. J Virol 77: 1195-1203.
    • (2003) J Virol , vol.77 , pp. 1195-1203
    • Yang, H.1    Makeyev, E.V.2    Butcher, S.J.3    Gaidelyte, A.4    Bamford, D.H.5
  • 26
    • 0033773926 scopus 로고    scopus 로고
    • The hepatitis C virus NS5B RNA-dependent RNA polymerase activity and susceptibility to inhibitors is modulated by metal cations
    • Alaoui-Lsmaili MH, Hamel M, L'Heureux L, Nicolas O, Bilimoria D, et al. (2000) The hepatitis C virus NS5B RNA-dependent RNA polymerase activity and susceptibility to inhibitors is modulated by metal cations. J Hum Virol 3: 306-316.
    • (2000) J Hum Virol , vol.3 , pp. 306-316
    • Alaoui-Lsmaili, M.H.1    Hamel, M.2    L'Heureux, L.3    Nicolas, O.4    Bilimoria, D.5
  • 27
    • 0032902564 scopus 로고    scopus 로고
    • Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli
    • Ferrari E, Wright-Minogue J, Fang JW, Baroudy BM, Lau JY, et al. (1999) Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli. J Virol 73: 1649-1654.
    • (1999) J Virol , vol.73 , pp. 1649-1654
    • Ferrari, E.1    Wright-Minogue, J.2    Fang, J.W.3    Baroudy, B.M.4    Lau, J.Y.5
  • 28
    • 0033948907 scopus 로고    scopus 로고
    • De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase
    • Zhong W, Uss AS, Ferrari E, Lau JY, Hong Z, (2000) De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase. J Virol 74: 2017-2022.
    • (2000) J Virol , vol.74 , pp. 2017-2022
    • Zhong, W.1    Uss, A.S.2    Ferrari, E.3    Lau, J.Y.4    Hong, Z.5
  • 29
  • 31
    • 3042666256 scopus 로고    scopus 로고
    • MUSCLE: multiple sequence alignment with high accuracy and high throughput
    • Edgar RC, (2004) MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 32: 1792-1797.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1792-1797
    • Edgar, R.C.1
  • 32
    • 77957675951 scopus 로고    scopus 로고
    • Assembly of Qβ viral RNA polymerase with host translational elongation factors EF-Tu and -Ts
    • Takeshita D, Tomita K, (2010) Assembly of Qβ viral RNA polymerase with host translational elongation factors EF-Tu and-Ts. Proc Natl Acad Sci USA 107: 15733-15738.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 15733-15738
    • Takeshita, D.1    Tomita, K.2
  • 33
    • 18744392514 scopus 로고    scopus 로고
    • RNA synthesis in a cage structural studies of reovirus polymerase λ3
    • Tao Y, Farsetta DL, Nibert ML, Harrison SC, (2002) RNA synthesis in a cage structural studies of reovirus polymerase λ3. Cell 111: 733-745.
    • (2002) Cell , vol.111 , pp. 733-745
    • Tao, Y.1    Farsetta, D.L.2    Nibert, M.L.3    Harrison, S.C.4
  • 34
    • 0031587827 scopus 로고    scopus 로고
    • Crystal structure of a pol α family replication DNA polymerase from bacteriophage RB69
    • Wang J, Sattar AK, Wang CC, Karam JD, Konigsberg WH, et al. (1997) Crystal structure of a pol α family replication DNA polymerase from bacteriophage RB69. Cell 89: 1087-1099.
    • (1997) Cell , vol.89 , pp. 1087-1099
    • Wang, J.1    Sattar, A.K.2    Wang, C.C.3    Karam, J.D.4    Konigsberg, W.H.5
  • 36
    • 0033581011 scopus 로고    scopus 로고
    • DNA polymerases: structural diversity and common mechanisms
    • Steitz TA, (1999) DNA polymerases: structural diversity and common mechanisms. J Biol Chem 274: 17395-17398.
    • (1999) J Biol Chem , vol.274 , pp. 17395-17398
    • Steitz, T.A.1
  • 37
    • 0034857266 scopus 로고    scopus 로고
    • Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain
    • Zhou BL, Pata JD, Steitz TA, (2001) Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain. Mol Cell 8: 427-437.
    • (2001) Mol Cell , vol.8 , pp. 427-437
    • Zhou, B.L.1    Pata, J.D.2    Steitz, T.A.3
  • 38
    • 33748146034 scopus 로고    scopus 로고
    • The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases
    • Bailey S, Wing RA, Steitz TA, (2006) The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases. Cell 126: 893-904.
    • (2006) Cell , vol.126 , pp. 893-904
    • Bailey, S.1    Wing, R.A.2    Steitz, T.A.3
  • 39
    • 0037423270 scopus 로고    scopus 로고
    • Characterization of the metal ion binding properties of the hepatitis C virus RNA polymerase
    • Bougie I, Charpentier S, Bisaillon M, (2003) Characterization of the metal ion binding properties of the hepatitis C virus RNA polymerase. J Biol Chem 278: 3868-3875.
    • (2003) J Biol Chem , vol.278 , pp. 3868-3875
    • Bougie, I.1    Charpentier, S.2    Bisaillon, M.3
  • 40
    • 40449114454 scopus 로고    scopus 로고
    • Metals in proteins: correlation between the metal-ion type, coordination number and the amino-acid residues involved in the coordination
    • Dokmanic I, Sikic M, Tomic S, (2008) Metals in proteins: correlation between the metal-ion type, coordination number and the amino-acid residues involved in the coordination. Acta Crystallogr D Biol Crystallogr 64: 257-263.
    • (2008) Acta Crystallogr D Biol Crystallogr , vol.64 , pp. 257-263
    • Dokmanic, I.1    Sikic, M.2    Tomic, S.3
  • 41
    • 0343238166 scopus 로고    scopus 로고
    • Mutation analysis of the GDD sequence motif of a calicivirus RNA-dependent RNA polymerase
    • Vazquez AL, Alonso JM, Parra F, (2000) Mutation analysis of the GDD sequence motif of a calicivirus RNA-dependent RNA polymerase. J Virol 74: 3888-3891.
    • (2000) J Virol , vol.74 , pp. 3888-3891
    • Vazquez, A.L.1    Alonso, J.M.2    Parra, F.3
  • 42
    • 1842289764 scopus 로고    scopus 로고
    • Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity
    • Lohmann V, Korner F, Herian U, Bartenschlager R, (1997) Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity. J Virol 71: 8416-8428.
    • (1997) J Virol , vol.71 , pp. 8416-8428
    • Lohmann, V.1    Korner, F.2    Herian, U.3    Bartenschlager, R.4
  • 43
    • 0026783262 scopus 로고
    • Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I
    • Sankar S, Porter AG, (1992) Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I. J Biol Chem 267: 10168-10176.
    • (1992) J Biol Chem , vol.267 , pp. 10168-10176
    • Sankar, S.1    Porter, A.G.2
  • 44
    • 0028893538 scopus 로고
    • Mutation of the aspartic acid residues of the GDD sequence motif of poliovirus RNA-dependent RNA polymerase results in enzymes with altered metal ion requirements for activity
    • Jablonski SA, Morrow CD, (1995) Mutation of the aspartic acid residues of the GDD sequence motif of poliovirus RNA-dependent RNA polymerase results in enzymes with altered metal ion requirements for activity. J Virol 69: 1532-1539.
    • (1995) J Virol , vol.69 , pp. 1532-1539
    • Jablonski, S.A.1    Morrow, C.D.2
  • 45
    • 79959318894 scopus 로고    scopus 로고
    • Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase
    • Lee JH, Alam I, Han KR, Cho S, Shin S, et al. (2011) Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase. J Gen Virol 92: 1607-1616.
    • (2011) J Gen Virol , vol.92 , pp. 1607-1616
    • Lee, J.H.1    Alam, I.2    Han, K.R.3    Cho, S.4    Shin, S.5
  • 46
    • 0031777848 scopus 로고    scopus 로고
    • Functional analysis of HIV-1 reverse transcriptase motif C: site-directed mutagenesis and metal cation interaction
    • Valverde-Garduno V, Gariglio P, Gutierrez L, (1998) Functional analysis of HIV-1 reverse transcriptase motif C: site-directed mutagenesis and metal cation interaction. J Mol Evol 47: 73-80.
    • (1998) J Mol Evol , vol.47 , pp. 73-80
    • Valverde-Garduno, V.1    Gariglio, P.2    Gutierrez, L.3
  • 47
    • 2542597119 scopus 로고    scopus 로고
    • The activity of selected RB69 DNA polymerase mutants can be restored by manganese ions: the existence of alternative metal ion ligands used during the polymerization cycle
    • Zakharova E, Wang J, Konigsberg W, (2004) The activity of selected RB69 DNA polymerase mutants can be restored by manganese ions: the existence of alternative metal ion ligands used during the polymerization cycle. Biochemistry 43: 6587-6595.
    • (2004) Biochemistry , vol.43 , pp. 6587-6595
    • Zakharova, E.1    Wang, J.2    Konigsberg, W.3
  • 49
    • 78651097570 scopus 로고    scopus 로고
    • Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase
    • Gong P, Peersen OB, (2010) Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc Natl Acad Sci USA 107: 22505-22510.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 22505-22510
    • Gong, P.1    Peersen, O.B.2
  • 51
    • 0346249755 scopus 로고    scopus 로고
    • De novo RNA synthesis by a recombinant classical swine fever virus RNA-dependent RNA polymerase
    • Yi GH, Zhang CY, Cao S, Wu HX, Wang Y, (2003) De novo RNA synthesis by a recombinant classical swine fever virus RNA-dependent RNA polymerase. Eur J Biochem 270: 4952-4961.
    • (2003) Eur J Biochem , vol.270 , pp. 4952-4961
    • Yi, G.H.1    Zhang, C.Y.2    Cao, S.3    Wu, H.X.4    Wang, Y.5
  • 52
    • 0031830417 scopus 로고    scopus 로고
    • Inhibition of ribozymes by deoxyribonucleotides and the origin of DNA
    • Leon PE, (1998) Inhibition of ribozymes by deoxyribonucleotides and the origin of DNA. J Mol Evol 47: 122-126.
    • (1998) J Mol Evol , vol.47 , pp. 122-126
    • Leon, P.E.1
  • 54
    • 57349112982 scopus 로고    scopus 로고
    • Oceans. Elements and evolution
    • Anbar AD, (2008) Oceans. Elements and evolution. Science 322: 1481-1483.
    • (2008) Science , vol.322 , pp. 1481-1483
    • Anbar, A.D.1
  • 55
    • 77953778296 scopus 로고    scopus 로고
    • History of biological metal utilization inferred through phylogenomic analysis of protein structures
    • Dupont CL, Butcher A, Valas RE, Bourne PE, Caetano-Anolles G, (2010) History of biological metal utilization inferred through phylogenomic analysis of protein structures. Proc Natl Acad Sci USA 107: 10567-10572.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10567-10572
    • Dupont, C.L.1    Butcher, A.2    Valas, R.E.3    Bourne, P.E.4    Caetano-Anolles, G.5
  • 56
    • 1242283840 scopus 로고    scopus 로고
    • The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase
    • Salgado PS, Makeyev EV, Butcher SJ, Bamford DH, Stuart DI, et al. (2004) The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure 12: 307-316.
    • (2004) Structure , vol.12 , pp. 307-316
    • Salgado, P.S.1    Makeyev, E.V.2    Butcher, S.J.3    Bamford, D.H.4    Stuart, D.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.