Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 13, 2011, Pages 9728-9736

  Price, Brandee A ^a   Sandoval, Ivette M ^a   Chan, Fung ^a   Simons, David L ^a   Wu, Samuel M ^a   Wensel, Theodore G ^a   Wilson, John H ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; MESSENGER RNA; PROLINE; RHODOPSIN; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN;

A WAVE; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B WAVE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRORETINOGRAPHY; FEMALE; GENE; GENOTYPING TECHNIQUE; HISTOLOGY; MOUSE; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETINA DEGENERATION; RETINA ROD; RETINITIS PIGMENTOSA; RHODOPSIN GENE; ANIMAL; C57BL MOUSE; CODON; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PHOTORECEPTOR INNER SEGMENT; PHOTORECEPTOR OUTER SEGMENT; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

ANIMALS; BLOTTING, NORTHERN; CODON; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; GENOTYPING TECHNIQUES; GREEN FLUORESCENT PROTEINS; HISTIDINE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROLINE; RECOMBINANT FUSION PROTEINS; RETINAL PHOTORECEPTOR CELL INNER SEGMENT; RETINAL PHOTORECEPTOR CELL OUTER SEGMENT; RETINITIS PIGMENTOSA; RHODOPSIN;

EID: 84863808803     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8654     Document Type: Article

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