The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site

Journal of Biological Chemistry

Volumn 287, Issue 29, 2012, Pages 24273-24283

  Jian, Xiaoying ^a   Gruschus, James M ^b   Sztul, Elizabeth ^c   Randazzo, Paul A ^a  

^a NCI   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXCHANGE FACTORS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INTER-DOMAIN; MYRISTOYLATION; NUCLEOTIDE EXCHANGE; PHOSPHATIDYLINOSITOL 4 ,5-BISPHOSPHATE; PHOSPHOINOSITIDES; PLECKSTRIN HOMOLOGY DOMAINS; SUBSTRATE SATURATION KINETICS; TUMOR CELL INVASION;

CELL ADHESION; KINETICS; PHOSPHOLIPIDS;

NUCLEOTIDES;

BRAG2 PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MYRISTIC ACID; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PLECKSTRIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; KINETICS; MYRISTYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

ADP-RIBOSYLATION FACTOR 1; ADP-RIBOSYLATION FACTORS; BINDING SITES; CELL LINE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; PROTEIN STRUCTURE, TERTIARY;

EID: 84863793694     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.368084     Document Type: Article

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