Farnesyltransferase inhibitor manumycin targets IL1β-Ras-HIF-1α axis in tumor cells of diverse origin

Inflammation

Volumn 35, Issue 2, 2012, Pages 516-519

  Sharma, Vivek ^a   Shaheen, Sk Sudipta ^a   Dixit, Deobrat ^a   Sen, Ellora ^a  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

Author keywords

Glioblastoma; HIF 1 ; Il 1 ; Ras

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MANUMYCIN; RAS PROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG TARGETING; HUMAN; HUMAN CELL; INFLAMMATION; LIVER CANCER; LUNG CANCER; TRANSCRIPTION REGULATION; TUMOR CELL; UTERINE CERVIX CANCER;

CELL LINE, TUMOR; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-1BETA; NEOPLASMS; POLYENES; POLYUNSATURATED ALKAMIDES; RAS PROTEINS;

EID: 84863785066     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-011-9340-6     Document Type: Article

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