Inhibition of interdomain motion in g-actin by the natural product latrunculin: A molecular dynamics study

Proteins: Structure, Function and Bioinformatics

Volumn 80, Issue 8, 2012, Pages 1998-2008

  Rennebaum, Sandra ^a   Caflisch, Amedeo ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Actin; Conformational transition; Domain rotation; Latrunculin; Motional correlation

Indexed keywords

ADENOSINE TRIPHOSPHATE; G ACTIN; LATRUNCULIN A;

ACTIN POLYMERIZATION; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE;

ACTINS; ADENOSINE TRIPHOSPHATE; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING SITES; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RABBITS; THIAZOLIDINES; WATER;

EUKARYOTA;

EID: 84863779713     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24088     Document Type: Article

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