Diverted total synthesis: Preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 23, 2005, Pages 8103-8108

  Fürstner, Alois ^a   Kirk, Douglas ^a   Fenster, Michäel D B ^a   Aïssa, Christophe ^a   De Souza, Dominic ^a   Müller, Oliver ^b  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

Alkyne metathesis; Natural products

Indexed keywords

2 THIAZOLIDINONE; ACTIN; ACTIN BINDING PROTEIN; LATRUNCULIN A; LATRUNCULIN B; MACROCYCLIC COMPOUND; MACROLIDE; NATURAL PRODUCT; OXAZOLIDINONE DERIVATIVE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CHIRALITY; MOUSE; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RING CLOSING METATHESIS; STRUCTURE ACTIVITY RELATION;

ACTINS; ALKYNES; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; HYDROGEN BONDING; LIGANDS; MICE; MICROFILAMENTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NIH 3T3 CELLS; PROTEIN BINDING; THIAZOLES; THIAZOLIDINES;

EID: 20444420894     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0501441102     Document Type: Article

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