메뉴 건너뛰기




Volumn 8, Issue 6, 2012, Pages 819-830

The polymorphisms in methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase, and the risk of colorectal cancer

Author keywords

Colorectal cancer; Folate; Methione synthase reductase; Methionine synthase; Methylenetetrahydrofolate reductase

Indexed keywords

5 METHYLTETRAHYDROFOLATE HOMOCYSTEINE METHYLTRANSFERASE; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; METHIONINE SYNTHASE REDUCTASE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2);

EID: 84863765612     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.4462     Document Type: Article
Times cited : (42)

References (59)
  • 1
    • 19844371353 scopus 로고    scopus 로고
    • Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model
    • Stempak JM, Sohn KJ, Chiang EP, Shane B, Kim YI. Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model. Carcinogenesis. 2005; 26(5): 981-90
    • (2005) Carcinogenesis. , vol.26 , Issue.5 , pp. 981-990
    • Stempak, J.M.1    Sohn, K.J.2    Chiang, E.P.3    Shane, B.4    Kim, Y.I.5
  • 2
    • 9244242523 scopus 로고    scopus 로고
    • Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis
    • Xu XL, Yu J, Zhang HY, Sun MH, Gu J, Du X, et al. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol. 2004; 10(23): 3441-54
    • (2004) World J Gastroenterol. , vol.10 , Issue.23 , pp. 3441-3454
    • Xu, X.L.1    Yu, J.2    Zhang, H.Y.3    Sun, M.H.4    Gu, J.5    Du, X.6
  • 4
    • 79951669632 scopus 로고    scopus 로고
    • MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic
    • Pardini B, Kumar R, Naccarati A, Prasad RB, Forsti A, Polakova V, et al. MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic. Mutat Res. 2011; 721(1): 74-80
    • (2011) Mutat Res. , vol.721 , Issue.1 , pp. 74-80
    • Pardini, B.1    Kumar, R.2    Naccarati, A.3    Prasad, R.B.4    Forsti, A.5    Polakova, V.6
  • 5
    • 10544249877 scopus 로고    scopus 로고
    • Human methionine synthase: CDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders
    • Leclerc D, Campeau E, Goyette P, Adjalla CE, Christensen B, Ross M, et al. Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Hum Mol Genet. 1996; 5(12): 1867-74
    • (1996) Hum Mol Genet. , vol.5 , Issue.12 , pp. 1867-1874
    • Leclerc, D.1    Campeau, E.2    Goyette, P.3    Adjalla, C.E.4    Christensen, B.5    Ross, M.6
  • 6
    • 13144282730 scopus 로고    scopus 로고
    • Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria
    • Leclerc D, Wilson A, Dumas R, Gafuik C, Song D, Watkins D, et al. Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria. Proceedings of the National Academy of Sciences. 1998; 95(6): 3059
    • (1998) Proceedings of the National Academy of Sciences. , vol.95 , Issue.6 , pp. 3059
    • Leclerc, D.1    Wilson, A.2    Dumas, R.3    Gafuik, C.4    Song, D.5    Watkins, D.6
  • 7
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom H, Milos R, Goyette P, Sheppard C, Matthews R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nature genetics. 1995; 10(1): 111-3
    • (1995) Nature genetics. , vol.10 , Issue.1 , pp. 111-113
    • Frosst, P.1    Blom, H.2    Milos, R.3    Goyette, P.4    Sheppard, C.5    Matthews, R.6
  • 8
    • 0032906750 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: Metabolic significance, risks and impact on folate requirement
    • Bailey LB, Gregory III JF. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. The Journal of nutrition. 1999; 129(5): 919-22
    • (1999) The Journal of nutrition. , vol.129 , Issue.5 , pp. 919-922
    • Bailey, L.B.1    Gregory III, J.F.2
  • 9
    • 0036016321 scopus 로고    scopus 로고
    • Linkage disequilibrium between the 677C> T and 1298A> C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer
    • Chen J, Ma J, Stampfer MJ, Palomeque C, Selhub J, Hunter DJ. Linkage disequilibrium between the 677C> T and 1298A> C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer. Pharmacogenetics and Genomics. 2002; 12(4): 339
    • (2002) Pharmacogenetics and Genomics. , vol.12 , Issue.4 , pp. 339
    • Chen, J.1    Ma, J.2    Stampfer, M.J.3    Palomeque, C.4    Selhub, J.5    Hunter, D.J.6
  • 10
    • 0034743914 scopus 로고    scopus 로고
    • The 1298A--> C polymorphism in methylenetetrahydrofolate reductase (MTHFR): In vitro expression and association with homocysteine
    • Weisberg IS, Jacques PF, Selhub J, Bostom AG, Chen Z, Curtis Ellison R, et al. The 1298A--> C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine. Atherosclerosis. 2001; 156(2): 409-15
    • (2001) Atherosclerosis. , vol.156 , Issue.2 , pp. 409-415
    • Weisberg, I.S.1    Jacques, P.F.2    Selhub, J.3    Bostom, A.G.4    Chen, Z.5    Curtis Ellison, R.6
  • 11
    • 0035874520 scopus 로고    scopus 로고
    • Association between polymorphisms of folate-and methionine-metabolizing enzymes and susceptibility to malignant lymphoma
    • Matsuo K, Suzuki R, Hamajima N, Ogura M, Kagami Y, Taji H, et al. Association between polymorphisms of folate-and methionine-metabolizing enzymes and susceptibility to malignant lymphoma. Blood. 2001; 97(10): 3205-9
    • (2001) Blood. , vol.97 , Issue.10 , pp. 3205-3209
    • Matsuo, K.1    Suzuki, R.2    Hamajima, N.3    Ogura, M.4    Kagami, Y.5    Taji, H.6
  • 12
    • 1642568671 scopus 로고    scopus 로고
    • Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk
    • Goode EL, Potter JD, Bigler J, Ulrich CM. Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev. 2004; 13(1): 157-62
    • (2004) Cancer Epidemiol Biomarkers Prev. , vol.13 , Issue.1 , pp. 157-162
    • Goode, E.L.1    Potter, J.D.2    Bigler, J.3    Ulrich, C.M.4
  • 13
    • 0034904708 scopus 로고    scopus 로고
    • The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations
    • Gaughan DJ, Kluijtmans LAJ, Barbaux S, McMaster D, Young IS, Yarnell JWG, et al. The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations. Atherosclerosis. 2001; 157(2): 451-6
    • (2001) Atherosclerosis. , vol.157 , Issue.2 , pp. 451-456
    • Gaughan, D.J.1    Kluijtmans, L.A.J.2    Barbaux, S.3    McMaster, D.4    Young, I.S.5    Yarnell, J.W.G.6
  • 14
    • 77649235525 scopus 로고    scopus 로고
    • Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy
    • Fernandez-Peralta AM, Daimiel L, Nejda N, Iglesias D, Medina Arana V, Gonzalez-Aguilera JJ. Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy. Int J Colorectal Dis. 2010; 25(2): 141-51
    • (2010) Int J Colorectal Dis. , vol.25 , Issue.2 , pp. 141-151
    • Fernandez-Peralta, A.M.1    Daimiel, L.2    Nejda, N.3    Iglesias, D.4    Medina Arana, V.5    Gonzalez-Aguilera, J.J.6
  • 15
    • 0035785560 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: Role in tumor development and significance of allelic loss in tumor progression
    • Ryan BM, Molloy AM, McManus R, Arfin Q, Kelleher D, Scott JM, et al. The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression. Int J Gastrointest Cancer. 2001; 30(3): 105-11
    • (2001) Int J Gastrointest Cancer. , vol.30 , Issue.3 , pp. 105-111
    • Ryan, B.M.1    Molloy, A.M.2    McManus, R.3    Arfin, Q.4    Kelleher, D.5    Scott, J.M.6
  • 16
    • 0037444389 scopus 로고    scopus 로고
    • A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer
    • Heijmans BT, Boer J, Suchiman HED, Cornelisse CJ, Westendorp RGJ, Kromhout D, et al. A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer. Cancer research. 2003; 63(6): 1249
    • (2003) Cancer research. , vol.63 , Issue.6 , pp. 1249
    • Heijmans, B.T.1    Boer, J.2    Suchiman, H.E.D.3    Cornelisse, C.J.4    Westendorp, R.G.J.5    Kromhout, D.6
  • 17
    • 80052334233 scopus 로고    scopus 로고
    • Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma
    • Guimaraes JL, Ayrizono Mde L, Coy CS, Lima CS. Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma. Tumour Biol. 2011; 32(5): 853-61
    • (2011) Tumour Biol. , vol.32 , Issue.5 , pp. 853-861
    • Guimaraes, J.L.1    Ayrizono Mde, L.2    Coy, C.S.3    Lima, C.S.4
  • 19
    • 34249951407 scopus 로고    scopus 로고
    • Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma
    • Lima CS, Nascimento H, Bonadia LC, Teori MT, Coy CS, Goes JR, et al. Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma. Int J Colorectal Dis. 2007; 22(7): 757-63
    • (2007) Int J Colorectal Dis. , vol.22 , Issue.7 , pp. 757-763
    • Lima, C.S.1    Nascimento, H.2    Bonadia, L.C.3    Teori, M.T.4    Coy, C.S.5    Goes, J.R.6
  • 20
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002; 21(11): 1539-58
    • (2002) Stat Med. , vol.21 , Issue.11 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 22
    • 0001937112 scopus 로고    scopus 로고
    • Assessing the influence of a single study in the meta-analysis estimate
    • Tobias A. Assessing the influence of a single study in the meta-analysis estimate. Stata Tech Bull. 1999; 47: 15-7
    • (1999) Stata Tech Bull. , vol.47 , pp. 15-17
    • Tobias, A.1
  • 23
    • 33748090675 scopus 로고    scopus 로고
    • A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints
    • Harbord RM, Egger M, Sterne JA. A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. Stat Med. 2006; 25(20): 3443-57
    • (2006) Stat Med. , vol.25 , Issue.20 , pp. 3443-3457
    • Harbord, R.M.1    Egger, M.2    Sterne, J.A.3
  • 24
    • 0036907435 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase codon 677 and 1298 polymorphisms and colon cancer in African Americans and whites
    • Keku T, Millikan R, Worley K, Winkel S, Eaton A, Biscocho L, et al. 5,10-Methylenetetrahydrofolate reductase codon 677 and 1298 polymorphisms and colon cancer in African Americans and whites. Cancer Epidemiol Biomarkers Prev. 2002; 11(12): 1611-21
    • (2002) Cancer Epidemiol Biomarkers Prev. , vol.11 , Issue.12 , pp. 1611-1621
    • Keku, T.1    Millikan, R.2    Worley, K.3    Winkel, S.4    Eaton, A.5    Biscocho, L.6
  • 26
    • 0036278536 scopus 로고    scopus 로고
    • A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability
    • Shannon B, Gnanasampanthan S, Beilby J, Iacopetta B. A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability. Gut. 2002; 50(4): 520-4
    • (2002) Gut. , vol.50 , Issue.4 , pp. 520-524
    • Shannon, B.1    Gnanasampanthan, S.2    Beilby, J.3    Iacopetta, B.4
  • 27
    • 80053584694 scopus 로고    scopus 로고
    • Association of MTHFR, MTR, MTRR, RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer
    • Jokic M, Brcic-Kostic K, Stefulj J, Catela Ivkovic T, Bozo L, Gamulin M, et al. Association of MTHFR, MTR, MTRR, RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer. DNA Cell Biol. 2011; 30(10): 771-6
    • (2011) DNA Cell Biol. , vol.30 , Issue.10 , pp. 771-776
    • Jokic, M.1    Brcic-Kostic, K.2    Stefulj, J.3    Catela Ivkovic, T.4    Bozo, L.5    Gamulin, M.6
  • 28
    • 38049119388 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: A case-control study in a population with relatively low folate intake
    • Sharp L, Little J, Brockton NT, Cotton SC, Masson LF, Haites NE, et al. Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case-control study in a population with relatively low folate intake. Br J Nutr. 2008; 99(2): 379-89
    • (2008) Br J Nutr. , vol.99 , Issue.2 , pp. 379-389
    • Sharp, L.1    Little, J.2    Brockton, N.T.3    Cotton, S.C.4    Masson, L.F.5    Haites, N.E.6
  • 29
    • 34447544092 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer
    • Zeybek U, Yaylim I, Yilmaz H, Agachan B, Ergen A, Arikan S, et al. Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer. Cell Biochem Funct. 2007; 25(4): 419-22
    • (2007) Cell Biochem Funct. , vol.25 , Issue.4 , pp. 419-422
    • Zeybek, U.1    Yaylim, I.2    Yilmaz, H.3    Agachan, B.4    Ergen, A.5    Arikan, S.6
  • 32
    • 11144236628 scopus 로고    scopus 로고
    • Colorectal cancer and the methylenetetrahydrofolate reductase 677C-> T and methionine synthase 2756A-> G polymorphisms: A study of 2,168 case-control pairs from the JANUS cohort
    • Ulvik A, Vollset SE, Hansen S, Gislefoss R, Jellum E, Ueland PM. Colorectal cancer and the methylenetetrahydrofolate reductase 677C-> T and methionine synthase 2756A-> G polymorphisms: a study of 2,168 case-control pairs from the JANUS cohort. Cancer Epidemiol Biomarkers Prev. 2004; 13(12): 2175-80
    • (2004) Cancer Epidemiol Biomarkers Prev. , vol.13 , Issue.12 , pp. 2175-2180
    • Ulvik, A.1    Vollset, S.E.2    Hansen, S.3    Gislefoss, R.4    Jellum, E.5    Ueland, P.M.6
  • 33
    • 0037312526 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase 677 C→ T polymorphism and risk of proximal colon cancer in north Italy
    • Toffoli G, Gafà R, Russo A, Lanza G, Dolcetti R, Sartor F, et al. Methylenetetrahydrofolate reductase 677 C→ T polymorphism and risk of proximal colon cancer in north Italy. Clinical cancer research. 2003; 9(2): 743-8
    • (2003) Clinical cancer research. , vol.9 , Issue.2 , pp. 743-748
    • Toffoli, G.1    Gafà, R.2    Russo, A.3    Lanza, G.4    Dolcetti, R.5    Sartor, F.6
  • 34
    • 0038523843 scopus 로고    scopus 로고
    • Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: A case control study
    • Pufulete M, Al-Ghnaniem R, Leather AJ, Appleby P, Gout S, Terry C, et al. Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology. 2003; 124(5): 1240-8
    • (2003) Gastroenterology. , vol.124 , Issue.5 , pp. 1240-1248
    • Pufulete, M.1    Al-Ghnaniem, R.2    Leather, A.J.3    Appleby, P.4    Gout, S.5    Terry, C.6
  • 35
    • 0344642951 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability
    • Plaschke J, Schwanebeck U, Pistorius S, Saeger HD, Schackert HK. Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability. Cancer Lett. 2003; 191(2): 179-85
    • (2003) Cancer Lett. , vol.191 , Issue.2 , pp. 179-185
    • Plaschke, J.1    Schwanebeck, U.2    Pistorius, S.3    Saeger, H.D.4    Schackert, H.K.5
  • 36
    • 0036848540 scopus 로고    scopus 로고
    • A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer
    • Sachse C, Smith G, Wilkie MJ, Barrett JH, Waxman R, Sullivan F, et al. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. Carcinogenesis. 2002; 23(11): 1839-49
    • (2002) Carcinogenesis. , vol.23 , Issue.11 , pp. 1839-1849
    • Sachse, C.1    Smith, G.2    Wilkie, M.J.3    Barrett, J.H.4    Waxman, R.5    Sullivan, F.6
  • 37
    • 0030615085 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
    • Ma J, Stampfer MJ, Giovannucci E, Artigas C, Hunter DJ, Fuchs C, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res. 1997; 57(6): 1098-102
    • (1997) Cancer Res. , vol.57 , Issue.6 , pp. 1098-1102
    • Ma, J.1    Stampfer, M.J.2    Giovannucci, E.3    Artigas, C.4    Hunter, D.J.5    Fuchs, C.6
  • 38
    • 0029855024 scopus 로고    scopus 로고
    • A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer
    • Chen J, Giovannucci E, Kelsey K, Rimm EB, Stampfer MJ, Colditz GA, et al. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Cancer Res. 1996; 56(21): 4862-4
    • (1996) Cancer Res. , vol.56 , Issue.21 , pp. 4862-4864
    • Chen, J.1    Giovannucci, E.2    Kelsey, K.3    Rimm, E.B.4    Stampfer, M.J.5    Colditz, G.A.6
  • 39
    • 77952641690 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population
    • Cui LH, Shin MH, Kweon SS, Kim HN, Song HR, Piao JM, et al. Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population. BMC Cancer. 2010; 10: 236
    • (2010) BMC Cancer. , vol.10 , pp. 236
    • Cui, L.H.1    Shin, M.H.2    Kweon, S.S.3    Kim, H.N.4    Song, H.R.5    Piao, J.M.6
  • 41
    • 33947685362 scopus 로고    scopus 로고
    • Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers
    • Chang SC, Lin PC, Lin JK, Yang SH, Wang HS, Li AF. Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers. Int J Colorectal Dis. 2007; 22(5): 483-9
    • (2007) Int J Colorectal Dis. , vol.22 , Issue.5 , pp. 483-489
    • Chang, S.C.1    Lin, P.C.2    Lin, J.K.3    Yang, S.H.4    Wang, H.S.5    Li, A.F.6
  • 42
    • 30344440353 scopus 로고    scopus 로고
    • Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan
    • Otani T, Iwasaki M, Hanaoka T, Kobayashi M, Ishihara J, Natsukawa S, et al. Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan. Nutr Cancer. 2005; 53(1): 42-50
    • (2005) Nutr Cancer. , vol.53 , Issue.1 , pp. 42-50
    • Otani, T.1    Iwasaki, M.2    Hanaoka, T.3    Kobayashi, M.4    Ishihara, J.5    Natsukawa, S.6
  • 43
    • 27944455699 scopus 로고    scopus 로고
    • One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan
    • Matsuo K, Ito H, Wakai K, Hirose K, Saito T, Suzuki T, et al. One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan. Carcinogenesis. 2005; 26(12): 2164-71
    • (2005) Carcinogenesis. , vol.26 , Issue.12 , pp. 2164-2171
    • Matsuo, K.1    Ito, H.2    Wakai, K.3    Hirose, K.4    Saito, T.5    Suzuki, T.6
  • 44
    • 17144420868 scopus 로고    scopus 로고
    • Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer
    • Jiang Q, Chen K, Ma X, Li Q, Yu W, Shu G, et al. Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer. Cancer Detect Prev. 2005; 29(2): 146-54
    • (2005) Cancer Detect Prev. , vol.29 , Issue.2 , pp. 146-154
    • Jiang, Q.1    Chen, K.2    Ma, X.3    Li, Q.4    Yu, W.5    Shu, G.6
  • 45
    • 19944366586 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: The Fukuoka Colorectal Cancer Study
    • Yin G, Kono S, Toyomura K, Hagiwara T, Nagano J, Mizoue T, et al. Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study. Cancer Sci. 2004; 95(11): 908-13
    • (2004) Cancer Sci. , vol.95 , Issue.11 , pp. 908-913
    • Yin, G.1    Kono, S.2    Toyomura, K.3    Hagiwara, T.4    Nagano, J.5    Mizoue, T.6
  • 46
    • 7744244730 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, alcohol intake, and risks of colon and rectal cancers in Korea
    • Kim DH, Ahn YO, Lee BH, Tsuji E, Kiyohara C, Kono S. Methylenetetrahydrofolate reductase polymorphism, alcohol intake, and risks of colon and rectal cancers in Korea. Cancer Lett. 2004; 216(2): 199-205
    • (2004) Cancer Lett. , vol.216 , Issue.2 , pp. 199-205
    • Kim, D.H.1    Ahn, Y.O.2    Lee, B.H.3    Tsuji, E.4    Kiyohara, C.5    Kono, S.6
  • 47
    • 0242478531 scopus 로고    scopus 로고
    • Methionine synthase reductase gene A66G polymorphism is associated with risk of colorectal cancer
    • Matsuo K, Hamajima N, Hirai T, Kato T, Inoue M, Takezaki T, et al. Methionine synthase reductase gene A66G polymorphism is associated with risk of colorectal cancer. Asian Pac J Cancer Prev. 2002; 3(4): 353-9
    • (2002) Asian Pac J Cancer Prev. , vol.3 , Issue.4 , pp. 353-359
    • Matsuo, K.1    Hamajima, N.2    Hirai, T.3    Kato, T.4    Inoue, M.5    Takezaki, T.6
  • 48
    • 0032799527 scopus 로고    scopus 로고
    • The 677C > T mutation in 5,10-methylenetetrahydrofolate reductase and colorectal cancer risk
    • Park KS, Mok JW, Kim JC. The 677C > T mutation in 5,10-methylenetetrahydrofolate reductase and colorectal cancer risk. Genet Test. 1999; 3(2): 233-6
    • (1999) Genet Test. , vol.3 , Issue.2 , pp. 233-236
    • Park, K.S.1    Mok, J.W.2    Kim, J.C.3
  • 49
    • 80053300270 scopus 로고    scopus 로고
    • Risk of colorectal cancer associated with the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the Kashmiri population
    • Sameer AS, Shah ZA, Nissar S, Mudassar S, Siddiqi MA. Risk of colorectal cancer associated with the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the Kashmiri population. Genet Mol Res. 2011; 10(2): 1200-10
    • (2011) Genet Mol Res. , vol.10 , Issue.2 , pp. 1200-1210
    • Sameer, A.S.1    Shah, Z.A.2    Nissar, S.3    Mudassar, S.4    Siddiqi, M.A.5
  • 51
    • 0035467993 scopus 로고    scopus 로고
    • Global cancer statistics in the year 2000
    • Parkin DM. Global cancer statistics in the year 2000. Lancet Oncol. 2001; 2(9): 533-43
    • (2001) Lancet Oncol. , vol.2 , Issue.9 , pp. 533-543
    • Parkin, D.M.1
  • 52
    • 27144526086 scopus 로고    scopus 로고
    • Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma
    • Kono S, Chen K. Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma. Cancer science. 2005; 96(9): 535-42
    • (2005) Cancer science. , vol.96 , Issue.9 , pp. 535-542
    • Kono, S.1    Chen, K.2
  • 53
    • 70350694056 scopus 로고    scopus 로고
    • Meta-and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: A HuGE-GSEC review
    • Taioli E, Garza M, Ahn Y, Bishop D, Bost J, Budai B, et al. Meta-and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review. American journal of epidemiology. 2009; 170(10): 1207-21
    • (2009) American journal of epidemiology. , vol.170 , Issue.10 , pp. 1207-1221
    • Taioli, E.1    Garza, M.2    Ahn, Y.3    Bishop, D.4    Bost, J.5    Budai, B.6
  • 54
    • 33846811416 scopus 로고    scopus 로고
    • MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations
    • Hubner RA, Houlston RS. MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations. International journal of cancer. 2007; 120(5): 1027-35
    • (2007) International journal of cancer. , vol.120 , Issue.5 , pp. 1027-1035
    • Hubner, R.A.1    Houlston, R.S.2
  • 55
    • 33845869785 scopus 로고    scopus 로고
    • Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: A meta-analysis
    • Huang Y, Han S, Li Y, Mao Y, Xie Y. Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: a meta-analysis. Journal of human genetics. 2007; 52(1): 73-85
    • (2007) Journal of human genetics. , vol.52 , Issue.1 , pp. 73-85
    • Huang, Y.1    Han, S.2    Li, Y.3    Mao, Y.4    Xie, Y.5
  • 56
    • 12344335470 scopus 로고    scopus 로고
    • Relationship between metabolic enzyme polymorphism and colorectal cancer
    • Chen K, Jiang QT, He HQ. Relationship between metabolic enzyme polymorphism and colorectal cancer. World J Gastroenterol. 2005; 11(3): 331-5
    • (2005) World J Gastroenterol. , vol.11 , Issue.3 , pp. 331-335
    • Chen, K.1    Jiang, Q.T.2    He, H.Q.3
  • 57
    • 31544481440 scopus 로고    scopus 로고
    • Associations between 5, 10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: A case-control study in an Indian population
    • Wang J, Gajalakshmi V, Jiang J, Kuriki K, Suzuki S, Nagaya T, et al. Associations between 5, 10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: A case-control study in an Indian population. International journal of cancer. 2006; 118(4): 991-7
    • (2006) International journal of cancer. , vol.118 , Issue.4 , pp. 991-997
    • Wang, J.1    Gajalakshmi, V.2    Jiang, J.3    Kuriki, K.4    Suzuki, S.5    Nagaya, T.6
  • 58
    • 0031416750 scopus 로고    scopus 로고
    • Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis
    • Zingg JM, Jones PA. Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. Carcinogenesis. 1997; 18(5): 869-82
    • (1997) Carcinogenesis. , vol.18 , Issue.5 , pp. 869-882
    • Zingg, J.M.1    Jones, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.