Methionine synthase reductase gene A66G polymorphism is: Associated with risk of colorectal cancer

Asian Pacific Journal of Cancer Prevention

Volumn 3, Issue 4, 2002, Pages 353-359

  Matsuo, Keitaro ^a,b   Hamajima, Nobuyuki ^a   Hirai, Takashi ^a   Kato, Tomoyuki ^a   Inoue, Manami ^a   Takezaki, Toshiro ^a   Tajima, Kazuo ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b Department of Gastroenterological Surgery ^*  (United States)

Author keywords

Colorectal cancer; Folate; Gene polymorphism; Methionine; Methionine synthase reductase

Indexed keywords

EID: 0242478531     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Bender RandLange S (2001). Adjusting for multiple testing-when and how? J Clin Epidemiol, 54, 343-9.
2. Brown CA, McKinney KQ, Kaufman JS, Gravel RA, Rozen R (2000). A common polymorphism in methionine synthase reductase increases risk of premature coronary artery disease. J Cardiovasc Risk, 7, 197-200.
3. Frosst P, Blom HJ, Milos R, et al (1995). A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet, 10, 111-3.
4. Giovannucci E, Rimm EB, Ascherio A, et al (1995). Alcohol, lowmethionine-low-folate diets, and risk of colon cancer in men. J Natl Cancer Inst, 87, 265-73.
5. Goelz SE, Vogelstein B, Hamilton SRandFeinberg AP (1985). Hypomethylation of DNA from benign and malignant human colon neoplasms. Science, 228, 187-90.
6. Goyette P, Sumner JS, Milos R, et al (1994). Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. Nat Genet, 7, 195-200.
7. Hamajima N, Matsuo K, Saito T, et al (2001a). Interleukin 1 polymorphisms, lifestyle factors, and Helicobacter pylori infection. Jpn J Cancer Res, 92, 383-9.
8. Hamajima N, Matsuo K, Yuasa H (2001b). Adjustment of prognostic effects in prevalent case-control studies on genotype. J Epidemiol, 11, 204-10.
9. Hamajima N, Takezaki T, Matsuo K, et al (2001c). Genotype frequencies of Cyclooxygenase2 (COX2) rare polymorphisms for Japanese with and without colorectal cancer. Asian Pac J Cancer Prev, 2, 57-62.
10. Harmon DL, Shields DC, Woodside JV, et al (1999). Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations. Genet Epidemiol, 17, 298-309.
11. Hobbs CA, Sherman SL, Yi P, et al (2000). Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome. Am J Hum Genet, 67, 623-30.
12. Hoffman RM (1984). Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis. Biochim Biophys Acta, 738, 49-87.
13. Leclerc D, Campeau E, Goyette P, et al (1996). Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Hum Mol Genet, 5, 1867-74.
14. Leclerc D, Wilson A, Dumas R, et al (1998). Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria. Proc Natl Acad Sci USA, 95, 3059-64.
15. Ma J, Stampfer MJ, Christensen B, et al (1999). A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev, 8, 825-9.
16. Ma J, Stampfer MJ, Giovannucci E, et al (1997). Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res, 57, 1098-102.
17. Makos M, Nelkin BD, Lerman MI, et al (1992). Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer. Proc Natl Acad Sci USA, 89, 1929-33.
18. Marugame T, Tsuji E, Inoue H, et al (2000). Methylenetetrahydrofolate reductase polymorphism and risk of colorectal adenomas. Cancer Lett, 151, 181-6.
19. Matsuo K, Suzuki R, Hamajima N, et al (2001). Association between polymorphisms of folate- and methioninemetabolizing enzymes and susceptibility to malignant lymphoma. Blood, 97, 3205-9.
20. Shane B (1990). Folate metabolism. In: Folic Acid Metabolism in Health and Disease, Eds Picciano MF, Sokstad ELR and Gregory JF. Wiley-Liss, New York pp. 65-78.
21. Skibola CF, Smith MT, Kane E, et al (1999). Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc Natl Acad Sci USA, 96, 12810-5.
22. Slattery ML, Potter JD, Samowitz W, Schaffer D, Leppert M (1999). Methylenetetrahydrofolate reductase, diet, and risk of colon cancer. Cancer Epidemiol Biomarkers Prev, 8, 513-8.
23. Takezaki T, Hamajima N, Matsuo K, et al (2001). Association of polymorphisms in the beta-2 and beta-3 adrenoceptor genes with risk of colorectal cancer in Japanese. Int J Clin Oncol, 6, 117-22.
24. Ulrich CM, Kampman E, Bigler J, et al (1999). Colorectal adenomas and the C677T MTHFR polymorphism: evidence for gene-environment interaction? Cancer Epidemiol Biomarkers Prev, 8, 659-68.
25. Ulrich CM, Kampman E, Bigler J, et al (2000). Lack of association between the C677T MTHFR polymorphism and colorectal hyperplastic polyps. Cancer Epidemiol Biomarkers Prev, 9, 427-33.
26. van der Put NM, Gabreels F, Stevens EM, et al (1998). A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet, 62, 1044-51.
27. Wilson A, Platt R, Wu Q, et al (1999). A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida. Mol Genet Metab, 67, 317-23.