Identification and characterization of solvent-filled channels in human ferrochelatase

Biochemistry

Volumn 51, Issue 27, 2012, Pages 5422-5433

  Medlock, Amy E ^a   Najahi Missaoui, Wided ^a,b   Ross, Teresa A ^a,c   Dailey, Tamara A ^a   Burch, Joseph ^a   O'Brien, Jessica R ^a   Lanzilotta, William N ^a   Dailey, Harry A ^a  

^a University of Georgia   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c Athens Research and Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ACTIVE SITE POCKET; CATALYTIC CYCLES; CONSERVED RESIDUES; CYTOTOXIC; DYNAMIC NATURE; ENZYME MECHANISM; FERROCHELATASE; IN-VITRO; KINETIC STUDY; PROTEIN SURFACE; PROTOHEME; PROTOPORPHYRIN IX; REACTION MECHANISM; STRUCTURAL STUDIES; SURFACE RESIDUES; WATER ENTRY;

CATALYSIS; COORDINATION REACTIONS; ENZYMES; PORPHYRINS;

SOLVENTS;

FERROCHELATASE; HEME; IRON; PROTON; PROTOPORPHYRIN; SOLVENT;

ARTICLE; CATALYSIS; CHANNEL GATING; CHELATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; HUMAN; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SURFACE PROPERTY;

BIOCATALYSIS; CATALYTIC DOMAIN; FERROCHELATASE; HUMANS; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SOLVENTS;

EID: 84863749257     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300598g     Document Type: Article

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