-
1
-
-
0035966497
-
Biodegradable polymeric nanoparticles as drug delivery devices
-
DOI 10.1016/S0168-3659(00)00339-4, PII S0168365900003394
-
Soppimath K. S., Aminabhavi T. M., Kulkarni A. R., Rudzinski W. E., Biodegradable polymeric nanoparticles as drug delivery devices Journal of Controlled Release 2001 70 1-2 1 20 (Pubitemid 32144788)
-
(2001)
Journal of Controlled Release
, vol.70
, Issue.1-2
, pp. 1-20
-
-
Soppimath, K.S.1
Aminabhavi, T.M.2
Kulkarni, A.R.3
Rudzinski, W.E.4
-
3
-
-
67349191257
-
Nanoscale particles for polymer degradation and stabilization-Trends and future perspectives
-
Kumar A. P., Depan D., Singh Tomer N., Singh R. P., Nanoscale particles for polymer degradation and stabilization-Trends and future perspectives Progress in Polymer Science 2009 34 6 479 515
-
(2009)
Progress in Polymer Science
, vol.34
, Issue.6
, pp. 479-515
-
-
Kumar, A.P.1
Depan, D.2
Singh Tomer, N.3
Singh, R.P.4
-
4
-
-
0035150352
-
Cannabinoid receptors and pain
-
DOI 10.1016/S0301-0082(00)00031-9, PII S0301008200000319
-
Pertwee R. G., Cannabinoid receptors and pain Progress in Neurobiology 2001 63 5 569 611 (Pubitemid 32115433)
-
(2001)
Progress in Neurobiology
, vol.63
, Issue.5
, pp. 569-611
-
-
Pertwee, R.G.1
-
5
-
-
1542284124
-
Are oral cannabinoids safe and effective in refractory neuropathic pain?
-
DOI 10.1016/S1090-3801(03)00084-3
-
Attal N., Brasseur L., Guirimand D., Clermond-Gnamien S., Atlami S., Bouhassira D., Are oral cannabinoids safe and effective in refractory neuropathic pain? European Journal of Pain 2004 8 2 173 177 (Pubitemid 38325885)
-
(2004)
European Journal of Pain
, vol.8
, Issue.2
, pp. 173-177
-
-
Attal, N.1
Brasseur, L.2
Guirimand, D.3
Clermond-Gnamien, S.4
Atlami, S.5
Bouhassira, D.6
-
6
-
-
34548096786
-
2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration
-
DOI 10.1021/jm070317a
-
Dziadulewicz E. K., Bevan S. J., Brain C. T., Coote P. R., Culshaw A. J., Davis A. J., Edwards L. J., Fisher A. J., Fox A. J., Gentry C., Groarke A., Hart T. W., Huber W., James I. F., Kesingland A., La Vecchia L., Loong Y., Lyothier I., McNair K., O'Farrell C., Peacock M., Portmann R., Schopfer U., Yaqoob M., Zadrobilek J., Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration Journal of Medicinal Chemistry 2007 50 16 3851 3856 (Pubitemid 47292048)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.16
, pp. 3851-3856
-
-
Dziadulewicz, E.K.1
Bevan, S.J.2
Brain, C.T.3
Coote, P.R.4
Culshaw, A.J.5
Davis, A.J.6
Edwards, L.J.7
Fisher, A.J.8
Fox, A.J.9
Gentry, C.10
Groarke, A.11
Hart, T.W.12
Huber, W.13
James, I.F.14
Kesingland, A.15
La Vecchia, L.16
Loong, Y.17
Lyothier, I.18
McNair, K.19
O'Farrell, C.20
Peacock, M.21
Portmann, R.22
Schopfer, U.23
Yaqoob, M.24
Zadrobilek, J.25
more..
-
7
-
-
63849298198
-
Cannabinoid receptor agonist 13, a novel cannabinoid agonist: First in human pharmacokinetics and safety
-
Gardin A., Kucher K., Kiese B., Appel-Dingemanse S., Cannabinoid receptor agonist 13, a novel cannabinoid agonist: first in human pharmacokinetics and safety Drug Metabolism and Disposition 2009 37 4 827 833
-
(2009)
Drug Metabolism and Disposition
, vol.37
, Issue.4
, pp. 827-833
-
-
Gardin, A.1
Kucher, K.2
Kiese, B.3
Appel-Dingemanse, S.4
-
8
-
-
0037320094
-
Target discovery and validation in the post-genomic era
-
DOI 10.1023/A:1022349805831
-
Butcher S. P., Target discovery and validation in the post-genomic era Neurochemical Research 2003 28 2 367 371 (Pubitemid 36207361)
-
(2003)
Neurochemical Research
, vol.28
, Issue.2
, pp. 367-371
-
-
Butcher, S.P.1
-
9
-
-
19444375104
-
DNA-based therapeutics and DNA delivery systems: A comprehensive review
-
ARTICLE 9
-
Patil S. D., Rhodes D. G., Burgess D. J., DNA-based therapeutics and DNA delivery systems: a comprehensive review AAPS Journal 2005 7 1, article 9 E61 E77
-
(2005)
AAPS Journal
, vol.7
, Issue.1
-
-
Patil, S.D.1
Rhodes, D.G.2
Burgess, D.J.3
-
10
-
-
58149166741
-
Novel composite microparticles for protein stabilization and delivery
-
Schoubben A., Blasi P., Giovagnoli S., Perioli L., Rossi C., Ricci M., Novel composite microparticles for protein stabilization and delivery European Journal of Pharmaceutical Sciences 2009 36 2-3 226 234
-
(2009)
European Journal of Pharmaceutical Sciences
, vol.36
, Issue.23
, pp. 226-234
-
-
Schoubben, A.1
Blasi, P.2
Giovagnoli, S.3
Perioli, L.4
Rossi, C.5
Ricci, M.6
-
11
-
-
70349279873
-
The effect of formulation variables on the characteristics of insulin-loaded poly(lactic-co-glycolic acid) microspheres prepared by a single phase oil in oil solvent evaporation method
-
Hamishehkar H., Emami J., Najafabadi A. R., Gilani K., Minaiyan M., Mahdavi H., Nokhodchi A., The effect of formulation variables on the characteristics of insulin-loaded poly(lactic-co-glycolic acid) microspheres prepared by a single phase oil in oil solvent evaporation method Colloids and Surfaces B 2009 74 1 340 349
-
(2009)
Colloids and Surfaces B
, vol.74
, Issue.1
, pp. 340-349
-
-
Hamishehkar, H.1
Emami, J.2
Najafabadi, A.R.3
Gilani, K.4
Minaiyan, M.5
Mahdavi, H.6
Nokhodchi, A.7
-
12
-
-
0034580371
-
The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
-
Jain R. A., The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices Biomaterials 2000 21 23 2475 2490
-
(2000)
Biomaterials
, vol.21
, Issue.23
, pp. 2475-2490
-
-
Jain, R.A.1
-
13
-
-
44449126102
-
Synthesis of lidocaine-loaded PLGA microparticles by flow focusing. Effects on drug loading and release properties
-
Holgado M. A., Arias J. L., Czar M. J., Alvarez-Fuentes J., Gan-Calvo A. M., Fernández-Arévalo M., Synthesis of lidocaine-loaded PLGA microparticles by flow focusing. Effects on drug loading and release properties International Journal of Pharmaceutics 2008 358 1-2 27 35
-
(2008)
International Journal of Pharmaceutics
, vol.358
, Issue.12
, pp. 27-35
-
-
Holgado, M.A.1
Arias, J.L.2
Czar, M.J.3
Alvarez-Fuentes, J.4
Gan-Calvo, A.M.5
Fernández-Arévalo, M.6
-
14
-
-
0024457576
-
Nanocapsule formation by interfacial polymer deposition following solvent displacement
-
Fessi H., Piusieux F., Devissaguet J. P., Ammoury N., Benita S., Nanocapsule formation by interfacial polymer deposition following solvent displacement International Journal of Pharmaceutics 1989 55 1 R1 R4
-
(1989)
International Journal of Pharmaceutics
, vol.55
, Issue.1
-
-
Fessi, H.1
Piusieux, F.2
Devissaguet, J.P.3
Ammoury, N.4
Benita, S.5
-
15
-
-
57849119582
-
Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS
-
DOI 10.1007/s00216-008-2456-3
-
Sergi M., Bafile E., Compagnone D., Curini R., D'ascenzo G., Romolo F. S., Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS Analytical and Bioanalytical Chemistry 2009 393 2 709 718 (Pubitemid 50319637)
-
(2009)
Analytical and Bioanalytical Chemistry
, vol.393
, Issue.2
, pp. 709-718
-
-
Sergi, M.1
Bafile, E.2
Compagnone, D.3
Curini, R.4
D'ascenzo, G.5
Romolo, F.S.6
-
16
-
-
41549119875
-
Determination of plasma and urine levels of 9-tetrahydrocannabinol and its main metabolite by liquid chromatography after solid-phase extraction
-
Mercolini L., Musenga A., Comin I., Baccini C., Conti M., Raggi M. A., Determination of plasma and urine levels of 9-tetrahydrocannabinol and its main metabolite by liquid chromatography after solid-phase extraction Journal of Pharmaceutical and Biomedical Analysis 2008 47 1 156 163
-
(2008)
Journal of Pharmaceutical and Biomedical Analysis
, vol.47
, Issue.1
, pp. 156-163
-
-
Mercolini, L.1
Musenga, A.2
Comin, I.3
Baccini, C.4
Conti, M.5
Raggi, M.A.6
-
17
-
-
33646409850
-
Development and validation of a method for the quantitation of 9 tetrahydrocannabinol in human plasma by high performance liquid chromatography after solid-phase extraction
-
Abbara C., Galy R., Benyamina A., Reynaud M., Bonhomme-Faivre L., Development and validation of a method for the quantitation of 9 tetrahydrocannabinol in human plasma by high performance liquid chromatography after solid-phase extraction Journal of Pharmaceutical and Biomedical Analysis 2006 41 3 1011 1016
-
(2006)
Journal of Pharmaceutical and Biomedical Analysis
, vol.41
, Issue.3
, pp. 1011-1016
-
-
Abbara, C.1
Galy, R.2
Benyamina, A.3
Reynaud, M.4
Bonhomme-Faivre, L.5
-
18
-
-
73249119750
-
A qualitative and quantitative HPTLC densitometry method for the analysis of cannabinoids in Cannabis sativa L
-
Fischedick J. T., Glas R., Hazekamp A., Verpoorte R., A qualitative and quantitative HPTLC densitometry method for the analysis of cannabinoids in Cannabis sativa L. Phytochemical Analysis 2009 20 5 421 426
-
(2009)
Phytochemical Analysis
, vol.20
, Issue.5
, pp. 421-426
-
-
Fischedick, J.T.1
Glas, R.2
Hazekamp, A.3
Verpoorte, R.4
-
19
-
-
0023037137
-
Review of analytical methods for identification and quantification of cannabis products
-
Vollner L., Bieniek D., Korte F., Review of analytical methods for identification and quantification of cannabis products Regulatory Toxicology and Pharmacology 1986 6 4 348 358 (Pubitemid 17219077)
-
(1986)
Regulatory Toxicology and Pharmacology
, vol.6
, Issue.4
, pp. 348-358
-
-
Vollner, L.1
Bieniek, D.2
Korte, F.3
-
20
-
-
69549127825
-
Protein-loaded PLGA microparticles engineered by flow focusing: Physicochemical characterization and protein detection by reversed-phase HPLC
-
Holgado M. A., Czar-Bernal M. J., Salas S., Arias J. L., lvarez-Fuentes J., Fernández-Arévalo M., Protein-loaded PLGA microparticles engineered by flow focusing: physicochemical characterization and protein detection by reversed-phase HPLC International Journal of Pharmaceutics 2009 380 1-2 147 154
-
(2009)
International Journal of Pharmaceutics
, vol.380
, Issue.12
, pp. 147-154
-
-
Holgado, M.A.1
Czar-Bernal, M.J.2
Salas, S.3
Arias, J.L.4
Lvarez-Fuentes, J.5
Fernández-Arévalo, M.6
-
21
-
-
43949085355
-
Development and validation of a reverse-phase liquid chromatographic method for the assay of lidocaine hydrochloride in alginate-Gantrez microspheres
-
Salas S., Talero B., Rabasco A. M., Gonzlez-Rodrguez M. L., Development and validation of a reverse-phase liquid chromatographic method for the assay of lidocaine hydrochloride in alginate-Gantrez microspheres Journal of Pharmaceutical and Biomedical Analysis 2008 47 3 501 507
-
(2008)
Journal of Pharmaceutical and Biomedical Analysis
, vol.47
, Issue.3
, pp. 501-507
-
-
Salas, S.1
Talero, B.2
Rabasco, A.M.3
Gonzlez-Rodrguez, M.L.4
-
22
-
-
0041471094
-
A validated HPLC method for the assay of xanthone and 3-methoxyxanthone in PLGA nanocapsules
-
Teixeira M., Afonso C. M. M., Pinto M. M. M. M., Barbosa C. M., A validated HPLC method for the assay of xanthone and 3-methoxyxanthone in PLGA nanocapsules Journal of Chromatographic Science 2003 41 7 371 376
-
(2003)
Journal of Chromatographic Science
, vol.41
, Issue.7
, pp. 371-376
-
-
Teixeira, M.1
Afonso, C.M.M.2
Pinto, M.M.M.M.3
Barbosa, C.M.4
-
25
-
-
79957861349
-
Validation of HPLC methods in pharmaceutical analysis
-
Lister A. S., Validation of HPLC methods in pharmaceutical analysis Separation Science and Technology 2005 6 C 191 217
-
(2005)
Separation Science and Technology
, vol.6 C
, pp. 191-217
-
-
Lister, A.S.1
-
26
-
-
77349115117
-
Development and validation of a rapid reversed-phase HPLC method for the determination of the non-nucleoside reverse transcriptase inhibitor dapivirine from polymeric nanoparticles
-
das Neves J., Sarmento B., Amiji M. M., Bahia M. F., Development and validation of a rapid reversed-phase HPLC method for the determination of the non-nucleoside reverse transcriptase inhibitor dapivirine from polymeric nanoparticles Journal of Pharmaceutical and Biomedical Analysis 2010 52 2 167 172
-
(2010)
Journal of Pharmaceutical and Biomedical Analysis
, vol.52
, Issue.2
, pp. 167-172
-
-
Das Neves, J.1
Sarmento, B.2
Amiji, M.M.3
Bahia, M.F.4
-
28
-
-
79953685905
-
Nanonization strategies for poorly water-soluble drugs
-
Chen H., Khemtong C., Yang X., Chang X., Gao J., Nanonization strategies for poorly water-soluble drugs Drug Discovery Today 2011 16 7-8 354 360
-
(2011)
Drug Discovery Today
, vol.16
, Issue.78
, pp. 354-360
-
-
Chen, H.1
Khemtong, C.2
Yang, X.3
Chang, X.4
Gao, J.5
-
29
-
-
79960283601
-
Insulin-loaded PLGA microparticles: Flow focusing versus double emulsion/solvent evaporation
-
Czar-Bernal M. J., Holgado M. A., Arias J. L., Muñoz-Rubio I., Martín-Banderas L., lvarez-Fuentes J., Fernández-Arévalo M., Insulin-loaded PLGA microparticles: flow focusing versus double emulsion/solvent evaporation Journal of Microencapsulation 2011 28 5 430 441
-
(2011)
Journal of Microencapsulation
, vol.28
, Issue.5
, pp. 430-441
-
-
Czar-Bernal, M.J.1
Holgado, M.A.2
Arias, J.L.3
Muñoz-Rubio, I.4
Martín-Banderas, L.5
Lvarez-Fuentes, J.6
Fernández-Arévalo, M.7
-
30
-
-
33644922055
-
Towards high-throughput production of uniformly encoded microparticles
-
DOI 10.1002/adma.200501976
-
Martín-Banderas L., Rodrguez-Gil A., Cebolla A., Chvez S., Berdn-lvarez T., Garcia J. M. F., Flores-Mosquera M., Gan-Calvo A. M., Towards high-throughput production of uniformly encoded microparticles Advanced Materials 2006 18 5 559 564 (Pubitemid 43385772)
-
(2006)
Advanced Materials
, vol.18
, Issue.5
, pp. 559-564
-
-
Martin-Banderas, L.1
Rodriguez-Gil, A.2
Cebolla, A.3
Chavez, S.4
Berdun-Alvarez, T.5
Garcia, J.M.F.6
Flores-Mosquera, M.7
Ganan-Calvo, A.M.8
-
31
-
-
33749620389
-
Straightforward production of encoded microbeads by Flow Focusing: Potential applications for biomolecule detection
-
DOI 10.1016/j.ijpharm.2006.05.032, PII S0378517306003905
-
Gan-Calvo A. M., Martín-Banderas L., Gonzlez-Prieto R., Rodrguez-Gil A., Berdn-lvarez T., Cebolla A., Chvez S., Flores-Mosquera M., Straightforward production of encoded microbeads by Flow Focusing: potential applications for biomolecule detection International Journal of Pharmaceutics 2006 324 1 19 26 (Pubitemid 44548288)
-
(2006)
International Journal of Pharmaceutics
, vol.324
, Issue.1
, pp. 19-26
-
-
Ganan-Calvo, A.M.1
Martin-Banderas, L.2
Gonzalez-Prieto, R.3
Rodriguez-Gil, A.4
Berdun-Alvarez, T.5
Cebolla, A.6
Chavez, S.7
Flores-Mosquera, M.8
-
32
-
-
0024457576
-
Nanocapsule formation by interfacial polymer deposition following solvent displacement
-
Fessi H., Piusieux F., Devissaguet J. P., Ammoury N., Benita S., Nanocapsule formation by interfacial polymer deposition following solvent displacement International Journal of Pharmaceutics 1989 55 1 R1 R4
-
(1989)
International Journal of Pharmaceutics
, vol.55
, Issue.1
-
-
Fessi, H.1
Piusieux, F.2
Devissaguet, J.P.3
Ammoury, N.4
Benita, S.5
-
33
-
-
0000952397
-
Guidelines for Collaborative Study procedure to validate characteristics of a method of analysis
-
Guidelines for Collaborative Study procedure to validate characteristics of a method of analysis Journal Association of Official Analytical Chemists 1989 72 694 704
-
(1989)
Journal Association of Official Analytical Chemists
, vol.72
, pp. 694-704
-
-
-
34
-
-
0001229909
-
Doing a thorough method validation can be tedious, but the consequences of not doing it right are wasted time, money, and resources
-
Green J. M., Doing a thorough method validation can be tedious, but the consequences of not doing it right are wasted time, money, and resources Analytical Chemistry 1996 68 305A 309A
-
(1996)
Analytical Chemistry
, vol.68
-
-
Green, J.M.1
-
35
-
-
0038701896
-
Limit of quantitation estimated with allowance for reproducibility requirements
-
pshtein N. A., Limit of quantitation estimated with allowance for reproducibility requirements Pharmaceutical Chemistry Journal 2002 36 11 631 633
-
(2002)
Pharmaceutical Chemistry Journal
, vol.36
, Issue.11
, pp. 631-633
-
-
Pshtein, N.A.1
-
36
-
-
77349114701
-
Method validation
-
Kazakevich Y. V. LoBrutto R. Hoboken, NJ, USA John Wiley Sons
-
LoBrutto R., Patel T., Kazakevich Y. V., LoBrutto R., Method validation HPLC for Pharmaceutical Scientists 2007 Hoboken, NJ, USA John Wiley Sons
-
(2007)
HPLC for Pharmaceutical Scientists
-
-
Lobrutto, R.1
Patel, T.2
-
37
-
-
31144470143
-
Flow focusing: A versatile technology to produce size-controlled and specific-morphology microparticles
-
DOI 10.1002/smll.200500087
-
Martín-Banderas L., Flores-Masquera M., Riesco-Chueca P., Rodrguez-Gil A., Cebolla A., Chvez S., Gan-Calvo A. M., Flow focusing: a versatile technology to produce size-controlled and specific-morphology microparticles Small 2005 1 7 688 692 (Pubitemid 43951724)
-
(2005)
Small
, vol.1
, Issue.7
, pp. 688-692
-
-
Martin-Banderas, L.1
Flores-Masquera, M.2
Riesco-Chueca, P.3
Rodriguez-Gil, A.4
Cebolla, A.5
Chavez, S.6
Ganan-Calvo, A.M.7
-
39
-
-
67449168069
-
Single and double emulsion manufacturing techniques of an amphiphilic drug in PLGA nanoparticles: Formulations of mithramycin and bioactivity
-
Cohen-Sela E., Teitlboim S., Chorny M., Koroukhov N., Danenberc H. D., Gao J., Golomb G., Single and double emulsion manufacturing techniques of an amphiphilic drug in PLGA nanoparticles: formulations of mithramycin and bioactivity Journal of Pharmaceutical Sciences 2009 98 4 1452 1462
-
(2009)
Journal of Pharmaceutical Sciences
, vol.98
, Issue.4
, pp. 1452-1462
-
-
Cohen-Sela, E.1
Teitlboim, S.2
Chorny, M.3
Koroukhov, N.4
Danenberc, H.D.5
Gao, J.6
Golomb, G.7
-
40
-
-
0000770688
-
Generation of steady liquid microthreads and micron-sized monodisperse sprays in gas streams
-
Gan-Calvo A. M., Generation of steady liquid microthreads and micron-sized monodisperse sprays in gas streams Physical Review Letters 1998 80 2 285 288
-
(1998)
Physical Review Letters
, vol.80
, Issue.2
, pp. 285-288
-
-
Gan-Calvo, A.M.1
-
41
-
-
77955489520
-
Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system
-
Xie H., Smith J. W., Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system Journal of Nanobiotechnology 2010 8, article 18
-
(2010)
Journal of Nanobiotechnology
, vol.818
-
-
Xie, H.1
Smith, J.W.2
-
42
-
-
77951257204
-
Interaction of biodegradable nanoparticles with intestinal cells: The effect of surface hydrophilicity
-
Gaumet M., Gurny R., Delie F., Interaction of biodegradable nanoparticles with intestinal cells: the effect of surface hydrophilicity International Journal of Pharmaceutics 2010 390 1 45 52
-
(2010)
International Journal of Pharmaceutics
, vol.390
, Issue.1
, pp. 45-52
-
-
Gaumet, M.1
Gurny, R.2
Delie, F.3
-
43
-
-
0038537239
-
PLG microsphere size controls drug release rate through several competing factors
-
DOI 10.1023/A:1024466407849
-
Berkland C., Kim K., Pack D. W., PLG microsphere size controls drug release rate through several competing factors Pharmaceutical Research 2003 20 7 1055 1062 (Pubitemid 36774277)
-
(2003)
Pharmaceutical Research
, vol.20
, Issue.7
, pp. 1055-1062
-
-
Berkland, C.1
Kim, K.2
Pack, D.W.3
|