Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system

Journal of Nanobiotechnology

Volumn 8, Issue , 2010, Pages

  Xie, Hui ^a   Smith, Jeffrey W ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODISTRIBUTIONS; CELLULAR UPTAKE; CONVENTIONAL METHODS; DRUG CARRIER; KEY FEATURE; MICRO-PARTICLES; NANOPRECIPITATION; PARTICLE POPULATION; PLGA NANOPARTICLES; POLY(LACTIC-CO-GLYCOLIC ACID); SIGNIFICANT FACTORS; THERAPEUTIC DELIVERY;

BIODEGRADABLE POLYMERS; DRUG DELIVERY; FUNCTIONAL POLYMERS;

NANOPARTICLES;

DRUG CARRIER; NANOFILM; NANOPARTICLE; POLYGLACTIN; POLYMER;

ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; CONCENTRATION (PARAMETERS); DRUG DELIVERY SYSTEM; FLOW RATE; INJECTION; MICROPARTICLE ENZYME IMMUNOASSAY; NANOFABRICATION; NANOFILTRATION; PARTICLE SIZE; POLYMERIZATION; PRECIPITATION; SCANNING ELECTRON MICROSCOPE;

EID: 77955489520     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/1477-3155-8-18     Document Type: Article

References (37)

1. Shive MS, Anderson JM. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 1997, 28:5-24. 10.1016/S0169-409X(97)00048-3, 10837562.
2. Fournier E, Passirani C, Montero-Menei CN, Benoit JP. Biocompatibility of implantable synthetic polymeric drug carriers: focus on brain biocompatibility. Biomaterials 2003, 24:3311-3331. 10.1016/S0142-9612(03)00161-3, 12763459.
3. Middleton JC, Tipton AJ. Synthetic biodegradable polymers as orthopedic devices. Biomaterials 2000, 21:2335-2346. 10.1016/S0142-9612(00)00101-0, 11055281.
4. Wu L, Ding J. In vitro degradation of three-dimensional porous poly(D,L-lactide-co-glycolide) scaffolds for tissue engineering. Biomaterials 2004, 25:5821-5830. 10.1016/j.biomaterials.2004.01.038, 15172494.
5. Giteau A, Venier-Julienne MC, Aubert-Pouessel A, Benoit JP. How to achieve sustained and complete protein release from PLGA-based microparticles?. Int J Pharm 2008, 350:14-26. 10.1016/j.ijpharm.2007.11.012, 18162341.
6. Mundargi RC, Babu VR, Rangaswamy V, Patel P, Aminabhavi TM. Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives. J Control Release 2008, 125:193-209. 10.1016/j.jconrel.2007.09.013, 18083265.
7. Campolongo MJ, Luo D. Drug delivery: Old polymer learns new tracts. Nat Mater 2009, 8:447-448. 10.1038/nmat2456, 19458640.
8. Cruz LJ, Tacken PJ, Fokkink R, Joosten B, Stuart MC, Albericio F, Torensma R, Figdor CG. Targeted PLGA nano-but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. J Control Release 2010, 144:118-126. 10.1016/j.jconrel.2010.02.013, 20156497.
9. Jaganathan KS, Vyas SP. Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally. Vaccine 2006, 24:4201-4211. 10.1016/j.vaccine.2006.01.011, 16446012.
10. Thomas C, Gupta V, Ahsan F. Influence of surface charge of PLGA particles of recombinant hepatitis B surface antigen in enhancing systemic and mucosal immune responses. Int J Pharm 2009, 379:41-50. 10.1016/j.ijpharm.2009.06.006, 19524654.
11. Sirsi SR, Schray RC, Wheatley MA, Lutz GJ. Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides. J Nanobiotechnology 2009, 7:1. 10.1186/1477-3155-7-1, 2671478, 19351396.
12. Zhang YM, Yang F, Yang YQ, Song FL, Xu AL. Recombinant interferon-alpha2b poly(lactic-co-glycolic acid) microspheres: pharmacokinetics-pharmacodynamics study in rhesus monkeys following intramuscular administration. Acta Pharmacol Sin 2008, 29:1370-1375. 10.1111/j.1745-7254.2008.00881.x, 18954532.
13. Jensen DM, Cun D, Maltesen MJ, Frokjaer S, Nielsen HM, Foged C. Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. J Control Release 2010, 142:138-145. 10.1016/j.jconrel.2009.10.010, 19840823.
14. Sivadas N, O'Rourke D, Tobin A, Buckley V, Ramtoola Z, Kelly JG, Hickey AJ, Cryan SA. A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins. Int J Pharm 2008, 358:159-167. 10.1016/j.ijpharm.2008.03.024, 18448288.
15. Ungaro F, d'Emmanuele di Villa Bianca R, Giovino C, Miro A, Sorrentino R, Quaglia F, La Rotonda MI. Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: in vivo deposition and hypoglycaemic activity after delivery to rat lungs. J Control Release 2009, 135:25-34. 10.1016/j.jconrel.2008.12.011, 19154761.
16. Li X, Xu Y, Chen G, Wei P, Ping Q. PLGA nanoparticles for the oral delivery of 5-Fluorouracil using high pressure homogenization-emulsification as the preparation method and in vitro/in vivo studies. Drug Dev Ind Pharm 2008, 34:107-115. 10.1080/03639040701484593, 18214762.
17. Naha PC, Kanchan V, Manna PK, Panda AK. Improved bioavailability of orally delivered insulin using Eudragit-L30D coated PLGA microparticles. J Microencapsul 2008, 25:248-256. 10.1080/02652040801903843, 18465311.
18. Pandey R, Khuller GK. Nanoparticle-based oral drug delivery system for an injectable antibiotic - streptomycin. Evaluation in a murine tuberculosis model. Chemotherapy 2007, 53:437-441. 10.1159/000110009, 17952004.
19. Shaikh J, Ankola DD, Beniwal V, Singh D, Kumar MN. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci 2009, 37:223-230. 10.1016/j.ejps.2009.02.019, 19491009.
20. Decuzzi P, Pasqualini R, Arap W, Ferrari M. Intravascular delivery of particulate systems: does geometry really matter?. Pharm Res 2009, 26:235-243. 10.1007/s11095-008-9697-x, 18712584.
21. Gratton SE, Ropp PA, Pohlhaus PD, Luft JC, Madden VJ, Napier ME, DeSimone JM. The effect of particle design on cellular internalization pathways. Proc Natl Acad Sci USA 2008, 105:11613-11618. 10.1073/pnas.0801763105, 2575324, 18697944.
22. Gu F, Zhang L, Teply BA, Mann N, Wang A, Radovic-Moreno AF, Langer R, Farokhzad OC. Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci USA 2008, 105:2586-2591. 10.1073/pnas.0711714105, 2268180, 18272481.
23. Siepmann J, Gopferich A. Mathematical modeling of bioerodible, polymeric drug delivery systems. Adv Drug Deliv Rev 2001, 48:229-247. 10.1016/S0169-409X(01)00116-8, 11369084.
24. Tamber H, Johansen P, Merkle HP, Gander B. Formulation aspects of biodegradable polymeric microspheres for antigen delivery. Adv Drug Deliv Rev 2005, 57:357-376. 10.1016/j.addr.2004.09.002, 15560946.
25. Tracy MA, Ward KL, Firouzabadian L, Wang Y, Dong N, Qian R, Zhang Y. Factors affecting the degradation rate of poly(lactide-co-glycolide) microspheres in vivo and in vitro. Biomaterials 1999, 20:1057-1062. 10.1016/S0142-9612(99)00002-2, 10378806.
26. Desai MP, Labhasetwar V, Amidon GL, Levy RJ. Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm Res 1996, 13:1838-1845. 10.1023/A:1016085108889, 8987081.
27. Holgadoa MA, Cozar-Bernala MJ, Salasa S, Arias JL, Alvarez-Fuentesa J, Fernandez-Avevaloa M. Protein-loaded PLGA microparticles angineered by flow focusing: Physicochemical characterization and protein detection by reversed-phase HPLC. International Journal of Pharmaceutics 2009, 380:147-154. 10.1016/j.ijpharm.2009.07.017, 19635540.
28. Almeria B, Deng W, Fahmy T, Gomez A. Controlling the morphology of electrospray-generated PLGA microparticles for drug delivery. Journal of Colloid and Interface Science 2010, 343:125-133. 10.1016/j.jcis.2009.10.002, 20022337.
29. Yao J, Lim LK, Xie J, Wang C. Characterization of electrospraying process for polymeric particle fabrication. J Aerosol Sciences 2008, 39:987-1002.
30. Quevedo E, Steinbacher J, McQuade DT. Interfacial polymerization within a simplified microfluidic device: capturing capsules. Journal of the American Chemical Society 2005, 127:10498-10499. 10.1021/ja0529945, 16045331.
31. Feng S, Huang G. Effects of emulsifiers on the controlled release of paclitaxel (Taxol) from nanospheres of biodegradable polymers. J Control Release 2001, 71:53-69. 10.1016/S0168-3659(00)00364-3, 11245908.
32. Fessi H, Puixeux F, Devissaguet J-P, Ammoury N, Benita S. Nanocapsule formation by interfacial polymer deposition following solvent displacement. International Journal of Pharmacy 1989, 55:R1-R4.
33. Gaumet M, Vargas A, Gurny R, Delie F. Nanoparticles for drug delivery: the need for precision in reporting particle size parameters. Eur J Pharm Biopharm 2008, 69:1-9. 10.1016/j.ejpb.2007.08.001, 17826969.
34. Karnik R, Gu F, Basto P, Cannizzaro C, Dean L, Kyei-Manu W, Langer R, Farokhzad OC. Microfluidic platform for controlled synthesis of polymeric nanoparticles. Nano Lett 2008, 8:2906-2912. 10.1021/nl801736q, 18656990.
35. Gaumet M, Gurny R, Delie F. Fluorescent biodegradable PLGA particles with narrow size distributions: preparation by means of selective centrifugation. Int J Pharm 2007, 342:222-230. 10.1016/j.ijpharm.2007.05.001, 17574353.
36. Sternling CV, Scriven LE. Interfacial turbulence: Hydrodynamic instability and the marangoni effect. AIChE Journal 1959, 5:514-523.
37. Berg J. Interfacial hydrodynamcis: an overview. Canadian Metallurgy Quarterly 1982, 21:121-136.