Development and validation of a rapid reversed-phase HPLC method for the determination of the non-nucleoside reverse transcriptase inhibitor dapivirine from polymeric nanoparticles

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 2, 2010, Pages 167-172

  das Neves, José ^a   Sarmento, Bruno ^a,b   Amiji, Mansoor M ^c   Bahia, Maria Fernanda ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

^c NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Antiretroviral; Dapivirine; HIV 1; Microbicides; Nanoparticles; Poly(lactic co glycolic acid); RP HPLC

Indexed keywords

ACETONITRILE; DAPIVIRINE; NANOPARTICLE; POLYGLACTIN; POLYMER; POLYVINYL ALCOHOL; TRIFLUOROACETIC ACID;

ACCURACY; ARTICLE; CHROMATOGRAPHY; DRUG DETERMINATION; DRUG RELEASE; DRUG STRUCTURE; FLOW RATE; IN VITRO STUDY; OXIDATION; PH; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TEMPERATURE; ULTRAVIOLET RADIATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; HIV REVERSE TRANSCRIPTASE; LACTIC ACID; LIMIT OF DETECTION; NANOPARTICLES; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; PYRIMIDINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET; TIME FACTORS;

EID: 77349115117     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.01.007     Document Type: Article

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