Peripheral nerve repair with cultured schwann cells: Getting closer to the clinics

The Scientific World Journal

Volumn 2012, Issue , 2012, Pages

  Rodrigues, Maria Carolina O ^a,b   Rodrigues, Antonio Antunes ^a,b   Glover, Loren E ^a   Voltarelli, Julio ^b   Borlongan, Cesario V ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOSUPPRESSIVE AGENT; NERVE GROWTH FACTOR; PROTEIN P75; PROTEIN S 100; TISSUE SCAFFOLD;

CELL THERAPY; DEMYELINATION; FACIAL NERVE INJURY; MESENCHYMAL STEM CELL; NERVE FIBER GROWTH; NERVE REGENERATION; NEURAL STEM CELL; NONHUMAN; OPTIC NERVE INJURY; PERIPHERAL NERVE; PERIPHERAL NERVE INJURY; PROTEIN EXPRESSION; REVIEW; SCHWANN CELL; SCIATIC NERVE INJURY; SENSORY NERVE; TISSUE ENGINEERING; ANIMAL; HUMAN; INSTRUMENTATION; TISSUE REGENERATION; TRANSPLANTATION;

ANIMALIA;

ANIMALS; GUIDED TISSUE REGENERATION; HUMANS; NERVE REGENERATION; PERIPHERAL NERVE INJURIES; SCHWANN CELLS; TISSUE SCAFFOLDS;

EID: 84863734823     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/2012/413091     Document Type: Review

References (85)

1. Asplund M., Nilsson M., Jacobsson A., von Holst H., Incidence of traumatic peripheral nerve injuries and amputations in Sweden between 1998 and 2006 Neuroepidemiology 2009 32 3 217 228
2. Evans G. R. D., Peripheral nerve injury: a review and approach to tissue engineered constructs The Anatomical Record 2001 263 4 396 404 (Pubitemid 32730268)
3. Taylor C. A., Braza D., Rice J. B., Dillingham T., The incidence of peripheral nerve injury in extremity trauma American Journal of Physical Medicine Rehabilitation 2008 87 5 381 385 (Pubitemid 351571126)
4. Kundu S. D., Roehl K. A., Eggener S. E., Antenor J. A., Han M., Catalona W. J., Potency, continence and complications in 3,477 consecutive radical retropubic prostatectomies Journal of Urology 2004 172 6 I 2227 2231 (Pubitemid 39507497)
5. May F., Matiasek K., Vroemen M., Caspers C., Mrva T., Arndt C., Schlenker B., Gais P., Brill T., Buchner A., Blesch A., Hartung R., Stief C., Gansbacher B., Weidner N., GDNF-transduced schwann cell grafts enhance regeneration of erectile nerves European Urology 2008 54 5 1179 1187
6. Campbell W. W., Evaluation and management of peripheral nerve injury Clinical Neurophysiology 2008 119 9 1951 1965
7. Sulaiman O. A., Gordon T., Effects of short- and long-term Schwann cell denervation on peripheral nerve regeneration, myelination, and size GLIA 2000 32 3 234 246
8. Dong M. M., Yi T. H., Stem cell and peripheral nerve injury and repair Facial Plastic Surgery 2010 26 5 421 427
9. Zhou L. N., Zhang J. W., Wang J. C., Lei W. L., Liu X. L., Zhou L. H., Bone marrow stromal and Schwann cells from adult rats can interact synergistically to aid in peripheral nerve repair even without intercellular contact in vitro Cellular Physiology and Biochemistry 2011 27 565 574
10. Wang X., Luo E., Li Y., Hu J., Schwann-like mesenchymal stem cells within vein graft facilitate facial nerve regeneration and remyelination Brain Research 2011 1383 71 80
11. Negishi H., Dezawa M., Oshitari T., Adachi-Usami E., Optic nerve regeneration within artificial Schwann cell graft in the adult rat Brain Research Bulletin 2001 55 3 409 419 (Pubitemid 32727901)
12. Perrin F. E., Lacroix S., Avilés-Trieueros M., David S., Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1 and interleukin-1 Wallerian degeneration Brain 2005 128 4 854 866 (Pubitemid 40516922)
13. Chaudhry V., Glass J. D., Griffin J. W., Wallerian degeneration in peripheral nerve disease Neurologic clinics 1992 10 3 613 627
14. Gilliatt R. W., Hjorth R. J., Nerve conduction during Wallerian degeneration in the baloon Journal of Neurology Neurosurgery and Psychiatry 1972 35 3 335 341
15. Touma E., Kato S., Fukui K., Koike T., Calpain-mediated cleavage of collapsin response mediator protein(CRMP)-2 during neurite degeneration in mice European Journal of Neuroscience 2007 26 12 3368 3381 (Pubitemid 350243516)
16. Zhai Q., Wang J., Kim A., Liu Q., Watts R., Hoopfer E., Mitchison T., Luo L., He Z., Involvement of the ubiquitin-proteasome system in the early stages of Wallerian degeneration Neuron 2003 39 2 217 225 (Pubitemid 36897545)
17. Beirowski B., Adalbert R., Wagner D., Grumme D. S., Addicks K., Ribchester R. R., Coleman M. P., The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves BMC Neuroscience 2005 6, article 6
18. Coleman M. P., Freeman M. R., Wallerian degeneration, WldS, and Nmnat Annual Review of Neuroscience 2010 33 245 267
19. Vargas M. E., Barres B. A., Why is Wallerian degeneration in the CNS so slow? Annual Review of Neuroscience 2007 30 153 179 (Pubitemid 47218754)
20. David S., Lacroix S., Molecular approaches to spinal cord repair Annual Review of Neuroscience 2003 26 411 440 (Pubitemid 37064940)
21. Gordon T., The role of neurotrophic factors in nerve regeneration Neurosurgical Focus 2009 26 2, article E3
22. Walsh S., Midha R., Practical considerations concerning the use of stem cells for peripheral nerve repair Neurosurgical Focus 2009 26 2 E2
23. Vrbova G., Mehra N., Shanmuganathan H., Tyreman N., Schachner M., Gordon T., Chemical communication between regenerating motor axons and Schwann cells in the growth pathway European Journal of Neuroscience 2009 30 3 366 375
24. Martini R., Schachner M., Brushart T. M., The L2/HNK-1 carbohydrate is preferentially expressed by previously motor axon-associated Schwann cells in reinnervated peripheral nerves The Journal of Neuroscience 1994 14 11 7180 7191 (Pubitemid 24336388)
25. Goethals S., Ydens E., Timmerman V., Janssens S., Toll-like receptor expression in the peripheral nerve GLIA 2010 58 14 1701 1709
26. Stoll G., Jander S., Myers R. R., Degeneration and regeneration of the peripheral nervous system: from Augustus Waller's observations to neuroinflammation Journal of the Peripheral Nervous System 2002 7 1 13 27 (Pubitemid 34246034)
27. George E. B., Glass J. D., Griffin J. W., Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels Journal of Neuroscience 1995 15 10 6445 6452
28. Gaudet A. D., Popovich P. G., Ramer M. S., Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury Journal of Neuroinflammation 2011 8, article 110
29. Gordon T., Tyreman N., Raji M. A., The basis for diminished functional recovery after delayed peripheral nerve repair Journal of Neuroscience 2011 31 14 5325 5334
30. Pfister L. A., Papalozos M., Merkle H. P., Gander B., Nerve conduits and growth factor delivery in peripheral nerve repair Journal of the Peripheral Nervous System 2007 12 2 65 82 (Pubitemid 46906328)
31. Hu J., Zhu Q. T., Liu X. L., Xu Y. B., Zhu J. K., Repair of extended peripheral nerve lesions in rhesus monkeys using acellular allogenic nerve grafts implanted with autologous mesenchymal stem cells Experimental Neurology 2007 204 2 658 666 (Pubitemid 46497053)
32. berg M., Ljungberg C., Edin E., Millqvist H., Nordh E., Theorin A., Terenghi G., Wiberg M., Clinical evaluation of a resorbable wrap-around implant as an alternative to nerve repair: a prospective, assessor-blinded, randomised clinical study of sensory, motor and functional recovery after peripheral nerve repair Journal of Plastic, Reconstructive and Aesthetic Surgery 2009 62 11 1503 1509
33. McKenzie I. A., Biernaskie J., Toma J. G., Midha R., Miller F. D., Skin-derived precursors generate myelinating Schwann cells for the injured and dysmyelinated nervous system Journal of Neuroscience 2006 26 24 6651 6660 (Pubitemid 44318347)
34. Udina E., Rodrguez F. J., Verd E., Espejo M., Gold B. G., Navarro X., FK506 enhances regeneration of axons across long peripheral nerve gaps repaired with collagen guides seeded with allogeneic Schwann cells GLIA 2004 47 2 120 129 (Pubitemid 39049986)
35. Reid A. J., Sun M., Wiberg M., Downes S., Terenghi G., Kingham P. J., Nerve repair with adipose-derived stem cells protects dorsal root ganglia neurons from apoptosis Neuroscience 2011 199 515 522
36. di Summa P. G., Kingham P. J., Raffoul W., Wiberg M., Terenghi G., Kalbermatten D. F., Adipose-derived stem cells enhance peripheral nerve regeneration Journal of Plastic, Reconstructive and Aesthetic Surgery 2010 63 9 1544 1552
37. Evans G. R., Brandt K., Katz S., Chauvin P., Otto L., Bogle M., Wang B., Meszlenyi R. K., Lu L., Mikos A. G., Patrick C. W., Bioactive poly(L-lactic acid) conduits seeded with Schwann cells for peripheral nerve regeneration Biomaterials 2002 23 3 841 848 (Pubitemid 33108959)
38. Koshimune M., Takamatsu K., Nakatsuka H., Inui K., Yamano Y., Ikada Y., Creating bioabsorbable Schwann cell coated conduits through tissue engineering Bio-Medical Materials and Engineering 2003 13 3 223 229 (Pubitemid 37039709)
39. Ladak A., Olson J., Tredget E. E., Gordon T., Differentiation of mesenchymal stem cells to support peripheral nerve regeneration in a rat model Experimental Neurology 2011 228 2 242 252
40. Kokai L. E., Ghaznavi A. M., Marra K. G., Incorporation of double-walled microspheres into polymer nerve guides for the sustained delivery of glial cell line-derived neurotrophic factor Biomaterials 2010 31 8 2313 2322
41. Dezawa M., Takahashi I., Esaki M., Takano M., Sawada H., Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells European Journal of Neuroscience 2001 14 11 1771 1776 (Pubitemid 35463694)
42. Marchesi C., Pluderi M., Colleoni F., Belicchi M., Meregalli M., Farini A., Parolini D., Draghi L., Fruguglietti M. E., Gavina M., Porretti L., Cattaneo A., Battistelli M., Prelle A., Moggio M., Borsa S., Bello L., Spagnoli D., Gaini S. M., Tanzi M. C., Bresolin N., Grimoldi N., Torrente Y., Skin-derived stem cells transplanted into resorbable guides provide functional nerve regeneration after sciatic nerve resection GLIA 2007 55 4 425 438
43. Ansselin A. D., Fink T., Davey D. F., Peripheral nerve regeneration through nerve guides seeded with adult Schwann cells Neuropathology and Applied Neurobiology 1997 23 5 387 398 (Pubitemid 27440479)
44. Sun F., Zhou K., Mi W.-J., Qiu J.-H., Repair of facial nerve defects with decellularized artery allografts containing autologous adipose-derived stem cells in a rat model Neuroscience Letters 2011 499 2 104 108
45. Cheng B., Chen Z., Fabricating autologous tissue to engineer artificial nerve Microsurgery 2002 22 4 133 137 (Pubitemid 34721640)
46. Zhang F., Blain B., Beck J., Zhang J., Chen Z., Chen Z. W., Lineaweaver W. C., Autogenous venous graft with one-stage prepared Schwann cells as a conduit for repair of long segmental nerve defects Journal of Reconstructive Microsurgery 2002 18 4 295 300 (Pubitemid 34556546)
47. Wakao S., Hayashi T., Kitada M., Kohama M., Matsue D., Teramoto N., Ose T., Itokazu Y., Koshino K., Watabe H., Iida H., Takamoto T., Tabata Y., Dezawa M., Long-term observation of auto-cell transplantation in non-human primate reveals safety and efficiency of bone marrow stromal cell-derived Schwann cells in peripheral nerve regeneration Experimental Neurology 2010 223 2 537 547
48. Fox I. K., MacKinnon S. E., Adult peripheral nerve disorders: nerve entrapment, repair, transfer, and brachial plexus disorders Plastic and Reconstructive Surgery 2011 127 5 105e 118e
49. Schlosshauer B., Dreesmann L., Schaller H. E., Sinis N., Synthetic nerve guide implants in humans: a comprehensive survey Neurosurgery 2006 59 4 740 747 (Pubitemid 44579574)
50. Kim Y. T., Haftel V. K., Kumar S., Bellamkonda R. V., The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps Biomaterials 2008 29 21 3117 3127
51. Liu J. J., Wang C. Y., Wang J. G., Ruan H. J., Fan C. Y., Peripheral nerve regeneration using composite poly(lactic acid-caprolactone)/nerve growth factor conduits prepared by coaxial electrospinning Journal of Biomedical Materials Research A 2011 96 1 13 20
52. Radtke C., Aizer A. A., Agulian S. K., Lankford K. L., Vogt P. M., Kocsis J. D., Transplantation of olfactory ensheathing cells enhances peripheral nerve regeneration after microsurgical nerve repair Brain Research 2009 1254 10 17
53. Verd E., Navarro X., Gudio-Cabrera G., Rodrguez F. J., Ceballos D., Valero A., Nieto-Sampedro M., Olfactory bulb ensheathing cells enhance peripheral nerve regeneration NeuroReport 1999 10 5 1097 1101 (Pubitemid 29317995)
54. You H., Wei L., Liu Y., Oudega M., Jiao S. S., Feng S. N., Chen Y., Chen J. M., Li B. C., Olfactory ensheathing cells enhance Schwann cell-mediated anatomical and functional repair after sciatic nerve injury in adult rats Experimental Neurology 2011 229 1 158 167
55. Lavdas A. A., Franceschini I., Dubois-Dalcq M., Matsas R., Schwann cells genetically engineered to express PSA show enhanced migratory potential without impairment of their myelinating ability in vitro GLIA 2006 53 8 868 878
56. Papastefanaki F., Chen J., Lavdas A. A., Thomaidou D., Schachner M., Matsas R., Grafts of Schwann cells engineered to express PSA-NCAM promote functional recovery after spinal cord injury Brain 2007 130 8 2159 2174 (Pubitemid 47236630)
57. Siu D., A new way of targeting to treat nerve injury International Journal of Neuroscience 2010 120 1 1 10
58. Zhang Y., Yeh J., Richardson P. M., Bo X., Cell adhesion molecules of the immunoglobulin superfamily in axonal regeneration and neural repair Restorative Neurology and Neuroscience 2008 26 2-3 81 96
59. Le Douarin N. M., Dupin E., Multipotentiality of the neural crest Current Opinion in Genetics and Development 2003 13 5 529 536 (Pubitemid 37204931)
60. Woodhoo A., Sommer L., Development of the Schwann cell lineage: from the neural crest to the myelinated nerve Glia 2008 56 14 1481 1490
61. Borlongan C. V., Remyelinating the transected peripheral nerve by fabricated Schwann cells derived from bone marrow Experimental Neurology 2010 225 2 243 245
62. Duncan I. D., Aguayo A. J., Bunge R. P., Wood P. M., Transplantation of rat Schwann cells grown in tissue culture into the mouse spinal cord Journal of the Neurological Sciences 1981 49 2 241 252 (Pubitemid 11183867)
63. Hood B., Levene H. B., Levi A. D., Transplantation of autologous Schwann cells for the repair of segmental peripheral nerve defects Neurosurgical Focus 2009 26 2 E4
64. Niapour A., Karamali F., Karbalaie K., Kiani A., Mardani M., Nasr-Esfahani M. H., Baharvand H., Novel method to obtain highly enriched cultures of adult rat Schwann cells Biotechnology Letters 2010 32 6 781 786
65. Le Blanc K., Ringdén O., Immunomodulation by mesenchymal stem cells and clinical experience Journal of Internal Medicine 2007 262 5 509 525 (Pubitemid 47620502)
66. Pittenger M. F., Mackay A. M., Beck S. C., Jaiswal R. K., Douglas R., Mosca J. D., Moorman M. A., Simonetti D. W., Craig S., Marshak D. R., Multilineage potential of adult human mesenchymal stem cells Science 1999 284 5411 143 147 (Pubitemid 29282067)
67. Keilhoff G., Langnaese K., Wolf G., Fansa H., Inhibiting effect of minocycline on the regeneration of peripheral nerves Developmental Neurobiology 2007 67 10 1382 1395 (Pubitemid 47242764)
68. Tohill M., Terenghi G., Stem-cell plasticity and therapy for injuries of the peripheral nervous system Biotechnology and Applied Biochemistry 2004 40 1 17 24 (Pubitemid 39070904)
69. Wong C. E., Paratore C., Dours-Zimmermann M. T., Rochat A., Pietri T., Suter U., Zimmermann D. R., Dufour S., Thiery J. P., Meijer D., Beermann F., Barrandon Y., Sommer L., Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin Journal of Cell Biology 2006 175 6 1005 1015 (Pubitemid 44969205)
70. Amoh Y., Li L., Yang M., Jiang P., Moossa A. R., Katsuoka K., Hoffman R. M., Hair follicle-derived blood vessels vascularize tumors in skin and are inhibited by doxorubicin Cancer Research 2005 65 6 2337 2343 (Pubitemid 40490144)
71. Biernaskie J., Sparling J. S., Liu J., Shannon C. P., Plemel J. R., Xie Y., Miller F. D., Tetzlaff W., Skin-derived precursors generate myelinating Schwann cells that promote remyelination and functional recovery after contusion spinal cord injury Journal of Neuroscience 2007 27 36 9545 9559 (Pubitemid 47492191)
72. Kingham P. J., Kalbermatten D. F., Mahay D., Armstrong S. J., Wiberg M., Terenghi G., Adipose-derived stem cells differentiate into a Schwann cell phenotype and promote neurite outgrowth in vitro Experimental Neurology 2007 207 2 267 274 (Pubitemid 47432883)
73. Niapour A., Karamali F., Nemati S., Co-transplantation of human embryonic stem cell-derived neural progenitors and schwann cells in a rat spinal cord contusion injury model elicits a distinct neurogenesis and functional recovery. Cell Transplantation. In press
74. Hill C. E., Moon L. D., Wood P. M., Bunge M. B., Labeled Schwann cell transplantation: cell loss, host Schwann cell replacement, and strategies to enhance survival GLIA 2006 53 3 338 343 (Pubitemid 43221355)
75. Sun F., Zhou K., Mi W.-J., Qiu J.-H., Combined use of decellularized allogeneic artery conduits with autologous transdifferentiated adipose-derived stem cells for facial nerve regeneration in rats Biomaterials 2011 32 32 8118 8128
76. Sabelman E. E., Hentz V. R., Clinical Trial of Peripheral Nerve Graft. ClinicalTrials.gov, 1999
77. AxoGen, Inc., Study of Nerve Reconstruction using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer. ClinicalTrials.gov, 2011
78. AxoGen, Inc., Avance Nerve Graft: The Natural Connection. 2011, http://www.Axogeninc.com
79. AxoGen, Inc., Study of Nerve Reconstruction using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer. ClinicalTrials.gov, 2011
80. Blesch A., Uy H. S., Grill R. J., Cheng J. G., Patterson P. H., Tuszynski M. H., Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury Journal of Neuroscience 1999 19 9 3556 3566 (Pubitemid 29203135)
81. Lavdas A. A., Papastefanaki F., Thomaidou D., Matsas R., Schwann cell transplantation for CNS repair Current Medicinal Chemistry 2008 15 2 151 160 (Pubitemid 351234618)
82. Tan K., Lessieur E., Cutler A., Nerone P., Vasanji A., Asosingh K., Erzurum S., Anand-Apte B., Impaired function of circulating CD34 + CD45 - cells in patients with proliferative diabetic retinopathy Experimental Eye Research 2010 91 2 229 237
83. Wagner W., Bork S., Horn P., Krunic D., Walenda T., Diehlmann A., Benes V., Blake J., Huber F. X., Eckstein V., Boukamp P., Ho A. D., Aging and replicative senescence have related effects on human stem and progenitor cells Plos ONE 2009 4 6
84. Doorn J., Moll G., Le Blanc K., van Blitterswijk C., De Boer J., Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements Tissue Engineering B 2012 18 101 115
85. Moll G., Jitschin R., von Bahr L., Rasmusson-Duprez I., Sundberg B., Lnnies L., Elgue G., Nilsson-Ekdahl K., Mougiakakos D., Lambris J. D., Ringdén O., Blanc K., Nilsson B., Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses Plos ONE 2011 6 7