Mutual antagonism of TGF-beta and Interleukin-2 in cell survival and lineage commitment of induced regulatory T cells

Cell Death and Differentiation

Volumn 19, Issue 8, 2012, Pages 1277-1287

  Tischner, D ^a   Wiegers, G J ^a   Fiegl, H ^b   Drach, M ^c   Villunger, A ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY HOSPITAL INNSBRUCK   (Austria)

^c MEDICAL UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

activated cell autonomous cell death; activation induced cell death; regulatory T cells; TGF

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; FAS ANTIGEN; FAS LIGAND; INTERLEUKIN 2; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; GENE SILENCING; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CELL SURVIVAL; COLITIS; FAS LIGAND PROTEIN; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-2; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84863720747     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.7     Document Type: Article

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