The lipopolysaccharide from Capnocytophaga canimorsus reveals an unexpected role of the core-oligosaccharide in MD-2 binding

PLoS Pathogens

Volumn 8, Issue 5, 2012, Pages

  Ittig, Simon ^a   Lindner, Buko ^b   Stenta, Marco ^c   Manfredi, Pablo ^a   Zdorovenko, Evelina ^d   Knirel, Yuriy A ^d   dal Peraro, Matteo ^c   Cornelis, Guy R ^a   Zähringer, Ulrich ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b RESEARCH CENTER BORSTEL   (Germany)

^c EPFL   (Switzerland)

^d N D ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEOXY MANNO OCTULOSONIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; BIOLOGICAL FACTOR; CD14 ANTIGEN; GALACTOSAMINE; GLUCOSAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPID A; LIPOPOLYSACCHARIDE BINDING PROTEIN; MYELOID DIFFERENTIATION FACTOR 2; OLIGOSACCHARIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3 DEOXY MANNO OCT 2 ULOPYRANOSONIC ACID; 3-DEOXY-MANNO-OCT-2-ULOPYRANOSONIC ACID; ACUTE PHASE PROTEIN; CARRIER PROTEIN; ENDOTOXIN; LEUKOCYTE ANTIGEN; LIPOPOLYSACCHARIDE-BINDING PROTEIN; MEMBRANE PROTEIN; SUGAR ACID;

ANIMAL CELL; ARTICLE; BACTERIAL GENOME; BACTERIUM ADHERENCE; BIOTINYLATION; CAPNOCYTOPHAGA; CAPNOCYTOPHAGA CANIMORSUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ESCHERICHIA COLI; GENE STRUCTURE; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; HYDROGEN BOND; LIPOGENESIS; MACROPHAGE; MOLECULAR MODEL; MONOCYTE; MOUTH FLORA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; ANIMAL; CELL LINE; CELL STRAIN HEK293; CHEMICAL STRUCTURE; CHEMISTRY; DOG; METABOLISM; PATHOGENICITY; PROTEIN TERTIARY STRUCTURE; SECRETION (PROCESS);

CANIS FAMILIARIS; CAPNOCYTOPHAGA CANIMORSUS; ESCHERICHIA COLI;

ACUTE-PHASE PROTEINS; ANIMALS; ANTIGENS, CD; ANTIGENS, CD14; CAPNOCYTOPHAGA; CARRIER PROTEINS; CELL LINE; DOGS; ENDOTOXINS; HEK293 CELLS; HUMANS; INTERLEUKIN-6; LIPID A; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; SUGAR ACIDS; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863692469     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002667     Document Type: Article

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