Synthesis of gem-difluorinated 1,6-naphthyridine-5,7-diones

Tetrahedron

Volumn 68, Issue 34, 2012, Pages 6941-6947

  Piron, Karel ^a   Kenis, Sara ^a   Verniest, Guido ^a,c   Surmont, Riccardo ^a   Thuring, Jan Willem ^b   Ten Holte, Peter ^b   Deroose, Frederik ^b   De Kimpe, Norbert ^a  

^a GHENT UNIVERSITY   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2 BROMO 3 CYANOPYRIDINE; 6 (4 BROMOBENZYL) 8,8 DIFLUORO 1,6 NAPHTHYRIDINE 5,7(6H,8H) DIONE; 6 BENZYL 8,8 DIFLUORO 1,6 NAPHTHYRIDINE 5,7(6H,8H) DIONE; 7 CHLORO 4,4 DIFLUOROISOQUINOLINE 1,3(2H,4H) DIONE; 8,8 DIFLUORO 1,6 NAPHTHYRIDINE 5,7(6H,8H) DIONE; 8,8 DIFLUORO 6 (4 NITROBENZYL) 1,6 NAPHTHYRIDINE 5,7(6H,8H) DIONE; 8,8 DIFLUORO 6 METHYL 1,6 NAPHTHYRIDINE 5,7(6H,8H) DIONE; ACETIC ACID DERIVATIVE; COPPER; ETHYL BROMODIFLUOROACETATE; NAPHTHYRIDINE DERIVATIVE; NITRILE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMISTRY; CROSS COUPLING REACTION; CYCLIZATION; DEFLUORINATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; PRIORITY JOURNAL;

EID: 84863632982     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2012.05.122     Document Type: Article

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