Region-specific elevation of D1 receptor-mediated neurotransmission in the nucleus accumbens of SHR, a rat model of attention deficit/hyperactivity disorder

Neuropharmacology

Volumn 63, Issue 4, 2012, Pages 547-554

  Ohno, Yukihiro ^a   Okano, Motoki ^a   Masui, Atsushi ^a   Imaki, Junta ^a   Egawa, Mika ^a   Yoshihara, Chikako ^a   Tatara, Ayaka ^a   Mizuguchi, Yuto ^a   Sasa, Masashi ^b   Shimizu, Saki ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Nagisa Clinic   (Japan)

Author keywords

Attention deficit hyperactivity disorder (AD HD); D1 receptors; Fos expression; Hyperactivity; Nucleus accumbens; Spontaneously hypertensive rat (SHR)

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DOPAMINE 1 RECEPTOR; PROTEIN FOS;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENTION DEFICIT DISORDER; BEHAVIOR DISORDER; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOREACTIVITY; JUVENILE ANIMAL; MALE; MOBILIZATION; NEUROCHEMISTRY; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REARING; SPONTANEOUSLY HYPERTENSIVE RAT; THALAMUS;

ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BEHAVIOR, ANIMAL; BENZAZEPINES; BRAIN MAPPING; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DOPAMINE ANTAGONISTS; EXPLORATORY BEHAVIOR; MALE; NERVE TISSUE PROTEINS; NEURONS; NUCLEUS ACCUMBENS; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, INBRED SHR; RECEPTORS, DOPAMINE D1; SYNAPTIC TRANSMISSION; UP-REGULATION;

EID: 84863620852     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.04.031     Document Type: Article

References (74)

1. M.R. Adams, E.P. Brandon, E.H. Chartoff, R.L. Idzerda, D.M. Dorsa, and G.S. McKnight Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice Proc. Natl. Acad. Sci. USA 94 1997 12157 12161 (Pubitemid 27467859)
2. J.K. Allen, M. Wilkinson, E.C. Soo, J.P. Hui, T.D. Chase, and N. Carrey Chronic low dose Adderall XR down-regulates cfos expression in infantile and prepubertal rat striatum and cortex Neuroscience 169 2010 1901 1912
3. F.P. Bymaster, J.S. Katner, D.L. Nelson, S.K. Hemrick-Luecke, P.G. Threlkeld, J.H. Heiligenstein, S.M. Morin, D.R. Gehlert, and K.W. Perry Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder Neuropsychopharmacology 27 2002 699 711 (Pubitemid 35335888)
4. G. Beauvais, S. Jayanthi, M.T. McCoy, B. Ladenheim, and J.L. Cadet Differential effects of methamphetamine and SCH23390 on the expression of members of IEG families of transcription factors in the rat striatum Brain Res. 1318 2010 1 10
5. 2 receptor-expressing striatal neurons in response to cocaine and haloperidol J. Neurosci. 28 2008 5671 5685
6. 2-class causes opposite changes of fos expression in the rat cerebral cortex Eur. J. Neurosci. 17 2003 763 770 (Pubitemid 36315246)
7. E. Carboni, A. Silvagni, V. Valentini, and G. Di Chiara Effect of amphetamine, cocaine and depolarization by high potassium on extracellular dopamine in the nucleus accumbens shell of SHR rats. An in vivo microdyalisis study Neurosci. Biobehav. Rev. 27 2003 653 659 (Pubitemid 37414913)
8. T.D. Chase, N. Carrey, R.E. Brown, and M. Wilkinson Methylphenidate differentially regulates c-fos and fosB expression in the developing rat striatum Brain Res. Dev. Brain Res. 157 2005 181 191 (Pubitemid 40800418)
9. R.E. Coggeshall Fos, nociception and the dorsal horn Prog. Neurobiol. 77 2005 299 352 (Pubitemid 41815592)
10. N. Del Campo, S.R. Chamberlain, B.J. Sahakian, and T.W. Robbins The roles of dopamine and noradrenaline in the pathophysiology and treatment of attention-deficit/hyperactivity disorder Biol. Psychiatry 69 2011 e145 e157
11. 1-like receptor agonist on motor activity and c-fos expression in the frontal-striatal circuitry of SHR and Wistar-Kyoto rats Behav. Brain Funct. 2 2006 18
12. M. Ernst, A.J. Zametkin, J.A. Matochik, P.H. Jons, and R.M. Cohen DOPA decarboxylase activity in attention deficit hyperactivity disorder adults. A [fluorine-18]fluorodopa positron emission tomographic study J. Neurosci. 18 1998 5901 5907 (Pubitemid 28341366)
13. T.A. Esbenshade, K.E. Browman, R.S. Bitner, M. Strakhova, M.D. Cowart, and J.D. Brioni The histamine H3 receptor: an attractive target for the treatment of cognitive disorders Br. J. Pharmacol. 154 2008 1166 1181 (Pubitemid 351992052)
14. S.V. Faraone, R.H. Perlis, A.E. Doyle, J.W. Smoller, J.J. Goralnick, M.A. Holmgren, and P. Sklar Molecular genetics of attention-deficit/hyperactivity disorder Biol. Psychiatry 57 2005 1313 1323 (Pubitemid 40798551)
15. H. Forssberg, E. Fernell, S. Waters, N. Waters, and J. Tedroff Altered pattern of brain dopamine synthesis in male adolescents with attention deficit hyperactivity disorder Behav. Brain Funct. 2 2006 40
16. M. Gattu, J.R. Pauly, K.L. Boss, J.B. Summers, and J.J. Buccafusco Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. I Brain Res. 771 1997 89 103 (Pubitemid 27465694)
17. J.P. Genro, C. Kieling, L.A. Rohde, and M.H. Hutz Attention-deficit/ hyperactivity disorder and the dopaminergic hypotheses Expert Rev. Neurother. 10 2010 587 601
18. R. Gittelman-Klein, D.F. Klein, S. Katz, K. Saraf, and E. Pollack Comparative effects of methylphenidate and thioridazine in hyperkinetic children. I. Clinical results Arch. Gen. Psychiatry 33 1976 1217 1231
19. E.M. Gordon, M. Stollstorff, and C.J. Vaidya Using spatial multiple regression to identify intrinsic connectivity networks involved in working memory performance Hum. Brain Mapp. 2011 10.1002/hbm.21306
20. D.J. Heal, S.L. Smith, R.S. Kulkarni, and H.L. Rowley New perspectives from microdialysis studies in freely-moving, spontaneously hypertensive rats on the pharmacology of drugs for the treatment of ADHD Pharmacol. Biochem. Behav. 90 2008 184 197
21. E.D. Hendley, D.J. Wessel, D.G. Atwater, J. Gellis, D. Whitehorn, and W.C. Low Age, sex and strain differences in activity and habituation in SHR and WKY rats Physiol. Behav. 34 1985 379 383 (Pubitemid 15114607)
22. D.G. Herrera, and H.A. Robertson Activation of c-fos in the brain Prog. Neurobiol. 50 1996 83 107 (Pubitemid 26412595)
23. 2 agonists Neuroscience 113 2002 939 955 (Pubitemid 35245262)
24. 2 receptor antagonist, on Fos protein expression in the rat forebrain Pharmacol. Biochem. Behav. 63 1999 535 541 (Pubitemid 29356084)
25. K. Johnson, L. Churchill, M.A. Klitenick, M.S. Hooks, and P.W. Kalivas Involvement of the ventral tegmental area in locomotion elicited from the nucleus accumbens or ventral pallidum J. Pharmacol. Exp. Ther. 277 1996 1122 1131 (Pubitemid 27169028)
26. K.M. Kantak, T. Singh, K.A. Kerstetter, K.A. Dembro, M.M. Mutebi, R.C. Harvey, C.F. Deschepper, and L.P. Dwoskin Advancing the spontaneous hypertensive rat model of attention deficit/hyperactivity disorder Behav. Neurosci. 122 2008 340 357 (Pubitemid 351672325)
27. S. Knardahl, and K. Karlsen Passive-avoidance behavior of spontaneously hypertensive rats Behav. Neural Biol. 42 1984 9 22 (Pubitemid 15212276)
28. J. Kuntsi, G. McLoughlin, and P. Asherson Attention deficit hyperactivity disorder Neuromolecular Med. 8 2006 461 484 (Pubitemid 44547515)
29. D. Leo, E. Sorrentino, F. Volpicelli, M. Eyman, D. Greco, D. Viggiano, U. di Porzio, and C. Perrone-Capano Altered midbrain dopaminergic neurotransmission during development in an animal model of ADHD Neurosci. Biobehav. Rev. 27 2003 661 669 (Pubitemid 37414914)
30. C.S. Maldonado-Irizarry, and A.E. Kelley Differential behavioral effects following microinjection of an NMDA antagonist into nucleus accumbens subregions Psychopharmacology 116 1994 65 72 (Pubitemid 24279598)
31. K.M. Marchant, and D.M. Dorsa Differential induction of neurotensin and c-fos gene expression by typical versus atypical antipsychotics Proc. Natl. Acad. Sci. USA. 90 1993 3447 3451 (Pubitemid 23111383)
32. M. Martinez, A. Calvo-Torrent, and J. Herbert Mapping brain response to social stress in rodents with c-fos expression: a review Stress 5 2002 3 13 (Pubitemid 34241889)
33. 1 mechanisms involved in the antiparkinsonian effects of SKF 82958 (APB): studies of tremulous jaw movements in rats Psychopharmacology 143 1999 72 81 (Pubitemid 29189997)
34. F.J. McClernon, and S.H. Kollins ADHD and smoking: from genes to brain to behavior Ann. N. Y. Acad. Sci. 1141 2008 131 147
35. T.W. McKeon, and E.D. Hendley Brain monoamines and metabolites in hypertensive and hyperactive rat strains Clin. Exp. Hypertens. A 10 1988 971 994 (Pubitemid 19051344)
36. H. Miwa, K. Nishi, T. Fuwa, and Y. Mizuno Differential expression of c-fos following administration of two tremorgenic agents: harmaline and oxotremorine Neuroreport 11 2000 2385 2390 (Pubitemid 30622276)
37. J.I. Morgan, and T. Curran Stimulus-transription coupling in neuron: role of cellular immediate-early genes Trends Neurosci. 12 1989 459 462 (Pubitemid 19259026)
38. Y. Ohno, S. Shimizu, J. Imaki, S. Ishihara, N. Sofue, M. Sasa, and Y. Kawai Anticataleptic 8-OH-DPAT preferentially counteracts with haloperidol-induced Fos expression in the dorsolateral striatum and the core region of the nucleus accumbens Neuropharmacology 55 2008 717 723
39. Y. Ohno, S. Shimizu, Y. Harada, M. Morishita, S. Ishihara, K. Kumafuji, M. Sasa, and T. Serikawa Regional expression of Fos-like immunoreactivity following seizures in Noda Epileptic Rat (NER) Epilepsy Res. 87 2009 70 76
40. 1A agonistic anxiolytic agent, on haloperidol-induced catalepsy and forebrain Fos expression in mice J. Pharmacol. Sci. 109 2009 593 599
41. 2A antagonist Pharmacol. Biochem. Behav. 96 2010 175 180
42. Y. Ohno, S. Ishihara, T. Mashimo, N. Sofue, S. Shimizu, T. Imaoku, T. Tsurumi, M. Sasa, and T. Serikawa Scn1a missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures Neurobiol. Dis. 41 2011 261 269
43. T. Pattij, and L.J. Vanderschuren The neuropharmacology of impulsive behaviour Trends Pharmacol. Sci. 29 2008 192 199
44. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates sixth ed. 2007 Elsevier Massachusetts
45. G.M.L. Perry, T. Sagvolden, and S.V. Faraone Intra-individual variability in genetic and environmental models of attention-deficit/hyperactivity disorders Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B 2010 1094 1101
46. R.C. Pierce, and P.W. Kalivas Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine J. Pharmacol. Exp. Ther. 275 1995 1019 1029 (Pubitemid 26023636)
47. S.R. Pliszka The neuropsychopharmacology of attention-deficit/hyper- activity disorder Biol. Psychiatry 57 2005 1385 1390
48. H.H. Pothuizen, A.L. Jongen-Rêlo, and J. Feldon The effects of temporary inactivation of the core and the shell subregions of the nucleus accumbens on prepulse inhibition of the acoustic startle reflex and activity in rats Neuropsychopharmacology 30 2005 683 696 (Pubitemid 40397074)
49. L. Pulvirenti, R. Berrier, M. Kreifeldt, and G.F. Koob Modulation of locomotor activity by NMDA receptors in the nucleus accumbens core and shell regions of the rat Brain Res. 664 1994 231 236 (Pubitemid 24347619)
50. G.S. Robertson, H. Matsumura, and H.C. Fibiger Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity J. Pharmacol. Exp. Ther. 271 1994 1058 1066 (Pubitemid 24377799)
51. V.A. Russell Dopamine hypofunction possibly results from a defect in glutamate-stimulated release of dopamine in the nucleus accumbens shell of a rat model for attention deficit hyperactivity disorder - the spontaneously hypertensive rat Neurosci. Biobehav. Rev. 27 2003 671 682 (Pubitemid 37414915)
52. V.A. Russell In vitro glutamate-stimulated release of dopamine from nucleus accumbens core and shell of spontaneously hypertensive rats Metab. Brain Dis. 18 2003 161 168 (Pubitemid 36718129)
53. A.G. Sadile Multiple evidence of a segmental defect in the anterior forebrain of an animal model of hyperactivity and attention deficit Neurosci. Biobehav. Rev. 24 2000 161 169 (Pubitemid 30026160)
54. T. Sagvolden Behavioral validation of the spontaneously hypertensive rats (SHR) as an animal model of attention-deficit/hyperactivity disorder (AD/HD) Neurosci. Biobehav. Rev. 24 2000 31 39 (Pubitemid 30026144)
55. T. Sagvolden The spontaneously hypertensive rat as a model of ADHD M.V. Solanto, A.F.T. Arnsten, F. Xavier Castellanos, Stimulant Drugs and ADHD Basic and Clinical Neuroscience 2001 Oxford University Press New York 221 237
56. T. Sagvolden, V.A. Russell, H. Aase, E.B. Johansen, and M. Farshbaf Rodent models of attention-deficit/hyperactivity disorder Biol. Psychiatry 57 2005 1239 1247 (Pubitemid 40798541)
57. T. Sagvolden, E.B. Johansen, G. Woien, S.I. Walaas, J. Storm-Mathisen, L.H. Bergersen, O. Hvalby, V. Jensen, H. Aase, V.A. Russell, P.R. Killeen, T. Dasbanerjee, F.A. Middleton, and S.V. Faraone The spontaneously hypertensive rat model of ADHD-the importance of selecting the appropriate reference strain Neuropharmacology 57 2009 619 626
58. T. Sagvolden, and E.B. Johansen Rat models of ADHD Curr. Top. Behav. Neurosci. 9 2012 301 315
59. M.V. Solanto Attention-deficit/hyperactivity disorder: clinical features M.V. Solanto, A.F.T. Arnsten, F. Xavier Castellanos, Stimulant Drugs and ADHD Basic and Clinical Neuroscience 2001 Oxford University Press New York 3 30
60. M. Stollstorff, J. Foss-Feig, E.H. Cook Jr., M.A. Stein, W.D. Gaillard, and C.J. Vaidya Neural response to working memory load varies by dopamine transporter genotype in children Neuroimage 53 2010 970 977
61. J.R. Sutterer, J. Perry, and W. DeVito Two-way shuttle box and lever-press avoidance in the spontaneously hypertensive and normotensive rat J. Comp. Physiol. Psychol. 94 1980 155 163 (Pubitemid 10094915)
62. C.J. Swanson, S. Heath, T.R. Stratford, and A.E. Kelley Differential behavioral responses to dopaminergic stimulation of nucleus accumbens subregions in the rat Pharmacol. Biochem. Behav. 58 1997 933 945 (Pubitemid 28108200)
63. H.A. Tilson, J.H. Chamberlain, J.A. Gylys, and J.P. Buyniski Behavioral suppressant effects of clonidine in strains of normotensive and hypertensive rats Eur. J. Pharmacol. 43 1977 99 105 (Pubitemid 8102203)
64. K.I. Ueno, H. Togashi, K. Mori, M. Matsumoto, S. Ohashi, A. Hoshino, T. Fujita, H. Saito, M. Minami, and M. Yoshioka Behavioural and pharmacological relevance of stroke-prone spontaneously hypertensive rats as an animal model of a developmental disorder Behav. Pharmacol. 13 2002 1 13 (Pubitemid 34174528)
65. K.I. Ueno, H. Togashi, M. Matsumoto, S. Ohashi, H. Saito, and M. Yoshioka Alpha4beta2 nicotinic acetylcholine receptor activation ameliorates impairment of spontaneous alternation behavior in stroke-prone spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder J. Pharmacol. Exp. Ther. 302 2002 95 100 (Pubitemid 34680426)
66. D. Viggiano, D. Vallone, L.A. Ruocco, and A.G. Sadile Behavioural, pharmacological, morpho-functional molecular studies reveal a hyperfunctioning mesocortical dopamine system in an animal model of attention deficit and hyperactivity disorder Neurosci. Biobehav. Rev. 27 2003 683 689 (Pubitemid 37414916)
67. D. Viggiano, D. Vallone, and A. Sadile Dysfunctions in dopamine systems and ADHD: evidence from animals and modeling Neural Plast. 11 2004 97 114 (Pubitemid 39089574)
68. N.D. Volkow, G.J. Wang, J. Newcorn, F. Telang, M.V. Solanto, J.S. Fowler, J. Logan, Y. Ma, K. Schulz, K. Pradhan, C. Wong, and J.M. Swanson Depressed dopamine activity in caudate and preliminary evidence of limbic involvement in adults with attention-deficit/hyperactivity disorder Arch. Gen. Psychiatry 64 2007 932 940 (Pubitemid 47230617)
69. Y. Watanabe, M. Fujita, Y. Ito, T. Okada, H. Kusuoka, and T. Nishimura Brain dopamine transporter in spontaneously hypertensive rats J. Nucl. Med. 38 1997 470 474 (Pubitemid 27376906)
70. J.S. Werry, and M.G. Aman Methylphenidate and haloperidol in children. Effects on attention, memory, and activity Arch. Gen. Psychiatry 32 1975 790 795
71. T.E. Wilens, J. Biederman, and T.J. Spencer Attention deficit/hyperactivity disorder across the lifespan Annu. Rev. Med. 53 2002 113 131 (Pubitemid 34177874)
72. D.S. Zahm Functional-anatomical implications of the nucleus accumbens core and shell subterritories Ann. N. Y. Acad. Sci. 877 1999 113 128 (Pubitemid 29351854)
73. 3 receptors Ann. N. Y. Acad. Sci. 1074 2006 1 12 (Pubitemid 44532806)
74. J. Zhang, L. Zhang, H. Jiao, Q. Zhang, D. Zhang, D. Lou, J.L. Katz, and M. Xu c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changes J. Neurosci. 26 2006 13287 13296 (Pubitemid 46011639)