ITRAQ-based proteomic profiling of breast cancer cell response to doxorubicin and TRAIL

Journal of Proteome Research

Volumn 11, Issue 7, 2012, Pages 3561-3572

  Leong, Sharon ^a   Nunez, Andrea C ^a   Lin, Mike Z ^a   Crossett, Ben ^b   Christopherson, Richard I ^b   Baxter, Robert C ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

apoptosis; biomarkers; breast cancer; cancer biology; endoplasmic reticulum; iTRAQ; mitochondria; pathway analysis; subcellular fractionation

Indexed keywords

DOXORUBICIN; MEMBRANE PROTEIN; PROTEIN SLC1A5; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANALYZER; APOPTOSIS; BREAST CANCER; CANCER CELL; CELL LYSATE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG RESPONSE; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; ISOBARIC TAG FOR RELATIVE AND ABSOLUTE QUANTITATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEOMICS; REVIEW;

AMINO ACID TRANSPORT SYSTEM ASC; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOTHERAPY, ADJUVANT; CYCLOPHILINS; DOXORUBICIN; ENDOPLASMIC RETICULUM; FEMALE; HUMANS; MEMBRANE PROTEINS; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA; NEOADJUVANT THERAPY; NEOPLASM PROTEINS; OXIDATIVE STRESS; PROTEOME; PROTEOMICS; TANDEM MASS SPECTROMETRY; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84863611405     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr2012335     Document Type: Review

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