Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 27, 2012, Pages 10996-11001

  Baker, Nicola ^a   Glover, Lucy ^a   Munday, Jane C ^b   Andrés, David Aguinaga ^b   Barrett, Michael P ^b   De Koning, Harry P ^b   Horn, David ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Aquaporin; Major instrinsic proteins; Transporter; Trypanosoma brucei; Trypanosomiasis

Indexed keywords

AQUAGLYCEROPORIN; AQUAGLYCEROPORIN 2; AQUAGLYCEROPORIN 3; MELARSOPROL; PENTAMIDINE; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ARTHROPOD LIFE CYCLE STAGE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CROSS RESISTANCE; DRUG SENSITIVITY; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TRYPANOSOMA BRUCEI;

ANIMALS; AQUAPORIN 2; AQUAPORIN 3; CELL LINE; DRUG RESISTANCE; FLAGELLA; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MELARSOPROL; MOLECULAR SEQUENCE DATA; PENTAMIDINE; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS; TSETSE FLIES;

HEXAPODA; TRYPANOSOMA BRUCEI;

EID: 84863585771     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202885109     Document Type: Article

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