Macrophage migration inhibitory factor (MIF) is essential for inflammatory and neuropathic pain and enhances pain in response to stress

Experimental Neurology

Volumn 236, Issue 2, 2012, Pages 351-362

  Alexander, Jessica K ^a,d   Cox, Gina M ^a   Tian, Jin Bin ^a,e   Zha, Alicia M ^a   Wei, Ping ^a   Kigerl, Kristina A ^a   Reddy, Mahesh K ^b   Dagia, Nilesh M ^b   Sielecki, Theis ^c   Zhu, Michael X ^a,e   Satoskar, Abhay R ^a   McTigue, Dana M ^a   Whitacre, Caroline C ^a   Popovich, Phillip G ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b Piramal Enterprises Limited   (India)

^c Cytokine PharmaSciences Inc   (United States)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

Axon; Cytokine; Glucocorticoids; Inflammation; Macrophage; Microglia; MIF; Neuroplasticity; Pain; Stress

Indexed keywords

GLUCOCORTICOID; MACROPHAGE MIGRATION INHIBITION FACTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; FEMALE; INFLAMMATORY PAIN; MENTAL STRESS; MICROGLIA; MOUSE; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SENSORY NERVE CELL; STRESS;

ANIMALS; CELLS, CULTURED; FEMALE; GANGLIA, SPINAL; HUMANS; INFLAMMATION; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURALGIA; PAIN MEASUREMENT; RATS, SPRAGUE-DAWLEY; STRESS, PSYCHOLOGICAL; UP-REGULATION;

EID: 84863500182     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.04.018     Document Type: Article

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