PDCD5 promotes cisplatin-induced apoptosis of glioma cells via activating mitochondrial apoptotic pathway

Cancer Biology and Therapy

Volumn 13, Issue 9, 2012, Pages 822-830

  Li, Haiyan ^a,b   Zhang, Xia ^a,c   Song, Xingguo ^a   Zhu, Faliang ^d   Wang, Qun ^a   Guo, Chun ^a   Liu, Chunmei ^a   Shi, Yongyu ^a   Ma, Chunhong ^a   Wang, Xiaoyan ^a   Zhang, Lining ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Qingdao Hiser Medical Center   (China)

^c YANTAI YUHUANGDING HOSPITAL   (China)

^d NONE

Author keywords

Apoptosis; Chemotherapy; Cisplatin; Glioma; PDCD5

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CISPLATIN; MITOCHONDRIAL PROTEIN; PROGRAMMED CELL DEATH 5; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CHEMOSENSITIVITY; COLONY FORMATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; GENE OVEREXPRESSION; GENE SILENCING; GLIOMA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; RAT;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BRAIN NEOPLASMS; CARBOPLATIN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CISPLATIN; ETOPOSIDE; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GLIOMA; HUMANS; MITOCHONDRIA; NEOPLASM PROTEINS; RNA INTERFERENCE; VINCRISTINE;

EID: 84863492729     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.20565     Document Type: Article

References (29)

1. Liu H, Wang Y, Zhang Y, Song Q, Di C, Chen G, et al. TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal. Biochem Biophys Res Commun 1999; 254:203-10; PMID:9920759; http://dx.doi. org/10.1006/bbrc.1998.9893.
2. Chen Y, Sun R, Han W, Zhang Y, Song Q, Di C, et al. Nuclear translocation of PDCD5 (TFAR19): an early signal for apoptosis? FEBS Lett 2001; 509:191-6; PMID:11741587; http://dx.doi.org/10.1016/S0014-5793(01)03062-9.
3. Zhang YM, Liu HT, Song QS, Ma DL. The apoptosis-accelerating effect of human recombinant TFAR19 protein on leukemia HL-60 cells. J Clin Immunol 2000; 16:8-11.
4. Rui M, Chen Y, Zhang Y, Ma D. Transfer of anti- TFAR19 monoclonal antibody into HeLa cells by in situ electroporation can inhibit the apoptosis. Life Sci 2002; 71:1771-8; PMID:12151055; http://dx.doi. org/10.1016/S0024- 3205(02)01943-4.
5. Chen LN, Wang Y, Ma DL, Chen YY. Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression. Apoptosis 2006; 11:101-11; PMID:16374546; http:// dx.doi.org/10.1007/s10495-005- 3134-y.
6. Salvi M, Xu D, Chen Y, Cabrelle A, Sarno S, Pinna LA. Programmed cell death protein 5 (PDCD5) is phosphorylated by CK2 in vitro and in 293T cells. Biochem Biophys Res Commun 2009; 387:606-10; PMID:19616514; http://dx.doi.org/ 10.1016/j.bbrc.2009.07.067.
7. Xu L, Chen Y, Song Q, Xu D, Wang Y, Ma D. PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage- induced apoptosis. Neoplasia 2009; 11:345-54; PMID:19308289.
8. Yang YH, Zhao M, Li WM, Lu YY, Chen YY, Kang B, et al. Expression of programmed cell death 5 gene involves in regulation of apoptosis in gastric tumor cells. Apoptosis 2006; 11:993-1001; PMID:16547588; http://dx.doi.org/10. 1007/s10495-006-6714-6.
9. Xu XR, Huang J, Xu ZG, Qian BZ, Zhu ZD, Yan Q, et al. Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. Proc Natl Acad Sci USA 2001; 98:15089-94; PMID:11752456; http://dx.doi. org/10.1073/pnas.241522398.
10. Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, Simon R, et al. Gene-expression profiles in hereditary breast cancer. N Engl J Med 2001; 344:539- 48; PMID:11207349; http://dx.doi.org/10.1056/ NEJM200102223440801.
11. Ruan GR, Qin YZ, Chen SS, Li JL, Ma X, Chang Y, et al. Abnormal expression of the programmed cell death 5 gene in acute and chronic myeloid leukemia. Leuk Res 2006; 30:1159-65; PMID:16507320; http://dx.doi.org/10.1016/j. leukres.2005.12.028.
12. Jiang TB, Li X, Zhou J, Zhou Y, Yuan H, Xiang H, et al. Expression of PDCD5 in multiple myeloma and its relation with BCL-2. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2008; 33:814-20; PMID:18812660.
13. Zhang X, Wang X, Song X, Wei Z, Zhou C, Zhu F, et al. Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas. Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas. Oncol Rep 2011; 25:353-8; PMID:21165576; http://dx.doi.org/10.3892/ or.2010.1103.
14. Chen C, Zhou H, Xu L, Liu X, Liu Z, Ma D, et al. Prognostic significance of downregulated expression of programmed cell death 5 in chondrosarcoma. Prognostic significance of downregulated expression of programmed cell death 5 in chondrosarcoma. J Surg Oncol 2010; 102:838-43; PMID:20872801; http:// dx.doi.org/10.1002/jso.21730.
15. Ma X, Ruan G, Wang Y, Li Q, Zhu P, Qin YZ, et al. Two single-nucleotide polymorphisms with linkage disequilibrium in the human programmed cell death 5 gene 5′ regulatory region affect promoter activity and the susceptibility of chronic myelogenous leukemia in Chinese population. Clin Cancer Res 2005; 11:8592- 9; PMID:16361542; http://dx.doi.org/10.1158/1078-0432.CCR-05-0039.
16. Gu L, Jiang Y, Wang Y, Yao W, Sun D, Ka W, et al. TFAR19 gene changes the biophysical properties of murine erythroleukemia cells. Cell Biochem Biophys 2005; 43:355-63; PMID:16247177; http://dx.doi. org/10.1385/CBB:43:3:355.
17. Spinola M, Meyer P, Kammerer S, Falvella FS, Boettger MB, Hoyal CR, et al. Association of the PDCD5 locus with lung cancer risk and prognosis in smokers. J Clin Oncol 2006; 24:1672-8; PMID:16549820; http:// dx.doi.org/10.1200/JCO.2005.04.4339.
18. Shi L, Song Q, Zhang Y, Lou Y, Wang Y, Tian L, et al. Potent antitumor activities of recombinant human PDCD5 protein in combination with chemotherapy drugs in K562 cells. Biochem Biophys Res Commun 2010; 396:224-30; PMID:20398626; http://dx.doi. org/10.1016/j.bbrc.2010.04.068.
19. Li H, Wang Q, Gao F, Zhu F, Wang X, Zhou C, et al. Reduced expression of PDCD5 is associated with high-grade astrocytic gliomas. Oncol Rep 2008; 20:573-9; PMID:18695908.
20. Stewart LA. Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet 2002; 359:1011-8; PMID:11937180; http://dx.doi. org/10.1016/S0140-6736(02)08091- 1.
21. Yin A, Jiang Y, Zhang X, Zhao J, Luo H. Transfection of PDCD5 sensitizes colorectal cancer cells to cisplatin-induced apoptosis in vitro and in vivo. Eur J Pharmacol 2010; 649:120-6.
22. Chen C, Zhou H, Xu L, Xu D, Wang Y, Zhang Y, et al. Recombinant human PDCD5 sensitizes chondrosarcomas to cisplatin chemotherapy in vitro and in vivo. Recombinant human PDCD5 sensitizes chondrosarcomas to cisplatin chemotherapy in vitro and in vivo. Apoptosis 2010; 15:805-13; PMID:20349137; http:// dx.doi.org/10.1007/s10495-010-0489-5.
23. Ruan GR, Chen SS, Chang Y, Li JL, Qin YZ, Li LD, et al. Adenovirus-mediated PDCD5 gene transfer sensitizes apoptosis of K562 cells induced by etoposide. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2007; 15:936-40; PMID:17956665.
24. Ruan GR, Zhao HS, Chang Y, Li JL, Qin YZ, Liu YR, et al. Adenovirus-mediated PDCD5 gene transfer sensitizes K562 cells to apoptosis induced by idarubicin in vitro and in vivo. Apoptosis 2008; 13:641-8; PMID:18401719; http://dx.doi.org/10.1007/s10495-008-0206-9.
25. Wang Y, Li D, Fan H, Tian L, Zhong Y, Zhang Y, et al. Cellular uptake of exogenous human PDCD5 protein. J Biol Chem 2006; 281:24803-17; PMID:16754680; http://dx.doi.org/10.1074/jbc.M600183200.
26. Wang D, Lippard SJ. Cellular processing of platinum anticancer drugs. Nat Review Drug Discovery 2005;4:307-20. (Pubitemid 41130944)
27. Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003; 22:7265- 79; PMID:14576837; http://dx.doi.org/10. 1038/sj.onc.1206933.
28. Fulda S, Debatin KM. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 2006; 25:4798-811; PMID:16892092; http://dx.doi. org/10.1038/sj.onc.1209608.
29. Korsmeyer SJ. BCL-2 gene family and the regulation of programmed cell death. Cancer Res 1999; 59:1693- 700; PMID:10197582.