Effects of margarine supplemented with t10c12 and c9t11 cla on atherosclerosis and steatosis in apoe/ldlr -/-mice

Journal of Nutrition, Health and Aging

Volumn 16, Issue 5, 2012, Pages 482-490

  Kostogrys, R B ^a   Franczyk Zarow, M ^a   Maslak, E ^a,c   Gajda, M ^b   Mateuszuk, L ^b,c   Chlopicki, S ^b,c  

^a UNIVERSITY OF AGRICULTURE IN KRAKOW   (Poland)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

ApoE ldlR ; Atherosclerosis; Cla isomers; Liver; Margarine

Indexed keywords

CHOLESTEROL; CONJUGATED LINOLEIC ACID; GLUCOSE; MARGARINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA ATHEROSCLEROSIS; ARTICLE; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; FATTY LIVER; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; LIVER WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALIA; MUS;

EID: 84863446285     PISSN: 12797707     EISSN: 17604788     Source Type: Journal    
DOI: 10.1007/s12603-011-0354-4     Document Type: Article

References (55)

1. Evans M, Brown J, Mcintosh M (2002) isomer-specific effects of conjugated linoleic acid (CLA) on adiposity and lipid metabolism. J Nutr Biochem 13: 508-516 (Pubitemid 35286669)
2. Wang Y, Jones Pjh (2004) The role of conjugated linoleic acid in human health. dietary conjugated linoleic acid and body composition. AM J Clin Nutr 79: 1153s-1158s
3. Belury MA (2002) Inhibition of carcinogenesis by conjugated linoleic acid: potential mechanisms of action. J Nutr 132: 2995-2998
4. Field CJ, Schley PD (2004) Evidence for potential mechanisms for the effect of conjugated linoleic acid on tumor metabolism and immune function: lessons from n-3fatty acids. Am J Clin Nutr 79: 1190s-1198s
5. Kritchevsky D, Tepper sa, wright s et al. (2002) influence of graded levels of conjugated linoleic acid (CLA) on experimental atherosclerosis in rabbits. Nutrition Research 22: 1275-1279 (Pubitemid 35316125)
6. Arbones-Mainar JM, navarro MA, Acin S et al. (2006) trans-10, cis-12-and CIS-9, trans-11-conjugated linoleic acid isomers selectively Modify hdl-apolipoprotein composition in apolipoprotein E Knockout Mice. J Nutr 136: 353-359 (Pubitemid 43228286)
7. Toomey S, Harhen B, Roche HM et al. (2006) Profound resolution of early atherosclerosis with conjugated linoleic acid. atherosclerosis 187: 40-49 (Pubitemid 43817000)
8. Franczyk-Zarow M, Kostogrys RB, szymczyk B et al. (2008) Functional effects of eggs, naturally enriched with conjugated linoleic acid (cla), on the blood lipid profile, development of atherosclerosis and composition of atherosclerotic plaque in apolipoprotein E and low density lipoprotein receptor double-knockout mice (apoE/ldlR -/-). Brit j nutr 99: 49-58 (Pubitemid 350286138)
9. O'Shea M, Bassaganya-Riera J, Mohede icM (2004) immunomodulatory properties of conjugated linoleic acid. am J Clin Nutr 79: 1199s-1206S
10. Azain MJ (2003) Conjugated linoleic acid and its effects on animal products and health in single stomached animals. Proc Nutr soc 62: 319-328
11. Raes K, DE smet S, Demeyer D (2004) Effects of dietary fatty acids on incorporation of long chain polyunsaturated fatty acids and conjugated linoleic acid in lamb, beef and pork meat. anim Feed sci tech 113: 199-221 (Pubitemid 38215164)
12. Givens DI (2005) The Role of animal nutrition in improving the nutritive value of animal-derived foods in relation to chronic disease. Proc Nutr Soc 64: 395-402 (Pubitemid 41160770)
13. Pisulewski PM, Franczyk M, Kostogrys RB (2005) heath-related effects of nutritionally modified foods of animal origin. J Anim Feed sci 14: 71s-85s
14. Schmid A, Collomb M, sieber R et al. (2006) conjugated linoleic acid in meat and meat products: a review. Meat sci 73: 29-41 (Pubitemid 43177742)
15. Jawien J, Gajda M, Rudling M et al. (2006a) inhibition of five lipoxygenase activating protein (Flap) by MK-886 decreases atherosclerosis in apoE/ldlRdouble knockout mice. Eur j clin invest 36: 141-146 (Pubitemid 43341263)
16. Olszanecki R, Jawien J, Gajda M et al. (2005) Effect of curcumin on atherosclerosis in apoE/ldlR-double knockout mice. J physiol pharmacol 56: 627-635 (Pubitemid 43127558)
17. Jawien J, Csanyi G, Gajda M et al. (2006b) ticlopidine attenuates progression of atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice. Eur J pharmacol 556: 129-35
18. Ishibashi S, Herz J, Maeda N et al. (1994) The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. proc natl acad sci USA 91: 4431-4435
19. Reeves PG, Nielsen FH, Fahey GC (1993). ain-93 purified diets for laboratory rodents: Final report of the american institute of nutrition ad hoc writing committee on the reformulation of the ain-76a rodent diet. J Nutr 123: 1939-1951 (Pubitemid 23342492)
20. Robertson AK, Rudling M, Zhou X et al. (2003) disruption of tgF-beta signaling in t cells accelerates atherosclerosis. J clin invest 112: 1342-1350 (Pubitemid 38057688)
21. Kiernan JA (1990) Histological & histochemical Methods. theory & practice, 2 nd edition. oxfort: pergamon press, great Britain BPCC, wheatons ltd, Exeter, pp 413-421
22. Ryder JW, portocarrero CP, Song XM, et al. (2001) isomer-specific antidiabetic properties of conjugated linoleic acid. improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression. diabetes 50: 1149-1157 (Pubitemid 32374547)
23. Park Y, Albright KJ, Liu W et al. (1997) Effect of conjugated linoleic acid on body composition in mice. lipids 32: 853-858 (Pubitemid 27360392)
24. Park Y, Albright KJ, Storkson JM et al. (1999) changes in body composition in mice during feeding and withdrawal of conjugated linoleic acid. lipids 34: 243-248 (Pubitemid 29169627)
25. West DB, Delany JP, camet PM et al. (1998) Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. Am J Physiol 275: R667-672
26. Park Y, Pariza MW (2007) Mechanisms of body fat modulation by conjugated linoleic acid (CLA). Food Res int , 40: 311-323 (Pubitemid 46124004)
27. Park Y (2009) Conjugated linoleic acid (CLA): good or bad trans fat? J Food com anal 22s: S4-S12
28. Warren JM, Simon VA, Bartolini G et al. (2003) trans-10,cis-12 cla increases liver and decreases adipose tissue lipids in mice: possible roles of specific Lipid metabolism Genes. Lipids 38: 497-504 (Pubitemid 36760236)
29. Ashwell MS, Ceddia RP, House RL et al. (2010) trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis. J Nutr Biochem 21: 9, 848-855
30. Tsuboyama-Kasaoka N, Takahashi M, tanemura K, et al. (2000) conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. diabetes 49: 1534-1542
31. Clement l, Poirier H, Niot i, et al. (2002) dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. J Lipid Res 43: 1400-1409
32. Degrace P, Demizieux L, Gresti J et al. (2004) hepatic steatosis is not due to impaired fatty acid oxidation capacities in c57Bl/6j mice fed the conjugated trans-10,cis-12-isomer of linoleic acid. J Nutr 134: 861-867 (Pubitemid 38456255)
33. Belury MA, Mahon A, Banni S (2003) the conjugated linoleic acid (CLA) isomer, t10c12-cla, is inversely associated with changes in body weight and serum leptin in subjects with type 2 diabetes mellitus. J Nutr 133: 257s-260s (Pubitemid 36070613)
34. Burdge GC, Lupoli B, Russell JJ et al. (2004) incorporation of cis-9,trans-11 or trans-10,cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men. J Lipid Res 45: 736-741 (Pubitemid 38405680)
35. Kostogrys RB, pisulewski PM (2010) Conjugated linoleic acid decreased serum triacyloglycerol and changed fatty acid composition in rat's liver. J Anim Feed sci 19: 484-494
36. Kostogrys RB, pisulewski PM (2010) Effect of conjugated linoleic acid (CLA) on lipid profile and liver histology in laboratory rats fed high-fructose diet. Environ toxicol pharmacol 30: 245-250
37. Chouinard P, Courneau L, Barbano D et al. (1999) conjugated linoleic acids alter milk fatty acid composition and inhibit milk fat secretion in dairy cows. J Nutr 129: 1579-1584 (Pubitemid 29344608)
38. Simon O, Manner K, Schafer K et al. (2000) Effects of conjugated linoleic acids on protein to fat proportions, fatty acids, and plasma lipids in broilers. Eur J Lipid sci Technol 102: 402-410
39. Szymczyk B, Pisulewski PM, Szczurek W et al. (2000) the effects of feeding conjugated linoleic acid (CLA) on rat growth performance, serum lipoproteins and subsequent lipid composition of selected rat tissues. J Sci Food Agr 80: 1553-1558 (Pubitemid 30597640)
40. Li Y, Watkins BA (1998) Conjugated Linoleic acids alter bone fatty acid composition and reduce ex vivo prostaglandin E2 biosynthesis in rats fed n-6 or n-3 fatty acids. Lipids 33: 417-425 (Pubitemid 28217388)
41. Evans M, Geigerman C, Curtis L et al. (2001) Trans-10, cis-12 conjugated linoleic acid reduces triglyceride content while differentially affecting ppar gamma2 and ap2 expression in 3t3-l1 preadipocytes. lipids 36: 1223-1232 (Pubitemid 34007976)
42. Munday JS, Thompson KG, James KAC (1999) dietary conjugated linoleic acids promote fatty streak formation in the c57Bl/6 mouse atherosclerosis model. Br J nutr 81: 251-255 (Pubitemid 29182191)
43. Valeille K, Gripois D, Blouquit MF et al. (2004) lipid atherogenic risk markers can be more favourably influenced by the cis-9 trans-11-octadecadienoate isomer than A conjugated linoleic acid mixture or fish oil in hamsters. Brit J Nutr 91: 191-199 (Pubitemid 38263535)
44. Tricon S, Burdge GC, Kew S et al. (2004) Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans. am J Clin Nutr 80: 614-620 (Pubitemid 41115525)
45. Yotosumoto H, Hara E, Naka s (1999) 10 trans, 12 cis linoleic acid reduces apolipoprotein B secretion in hepg2 cells. Food Research int 31: 403-409
46. Grundy SM, Denke MA (1990) Dietary influences on serum lipids and lipoproteins. J Lipid Res 31: 1149-1172 (Pubitemid 20224714)
47. Yeung ChH, Yang L, Huang y (2000) dietary conjugated linoleic acid mixture affects the activity of intestinal acyl coenzyme a: cholesterol acyltransferase in hamsters. Br J Nutr 84: 935-941 (Pubitemid 32106820)
48. Fernandez ML, west Kl (2005) Mechanisms by which dietary fatty acids modulate plasma lipids. J Nutr 135: 2075-2078 (Pubitemid 41298368)
49. Gonzalez FJ (2007) Animal models for human risk assessment: the peroxisome proliferator-activated receptor alpha-humanized mouse. Nutr Rev 65: s2-6
50. Belury MA, Moya-camarena SY, Liu KL et al. (1997) dietary conjugated linoleic acid induces peroxisome-specific enzyme accumulation and ornithine decarboxylase activity in mouse liver. J Nutr Biochem 8: 579-584 (Pubitemid 27460590)
51. Rasooly R, Kelley ds, greg j et al. (2007) dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Brit J Nutr 97: 58-66 (Pubitemid 46662059)
52. Mitchell PL, Mcleod RS (2008) conjugated linoleic acid and atherosclerosis: studies in animal models. Biochem. Cell Biol 86: 293-301
53. Kostogrys RB, Maślak E, Franczyk-Zarow M et al. (2011). Effects of trans-10,cis-12 and cis-9,trans-11 cla on atherosclerosis in apoE/ldlRs/s mice. Eur. J. Lipid sci technol 113, 572-583.
54. Nestel P, Fujii A, Allen T (2006) the cis-9,trans-11 isomer of conjugated linoleic acid (CLA) lowers plasma triglyceride and raises hdl cholesterol concentrations but does not suppress aortic atherosclerosis in diabetic apoE-deficient mice. atherosclerosis 189: 282-287 (Pubitemid 44634486)
55. Cooper MH, Miller JR, Mitchell PL et al. (2008) conjugated linoleic acid isomers have no effect on atherosclerosis and adverse effects on lipoprotein and liver lipid metabolism in apoE/ mice fed a high-cholesterol diet. Atherosclerosis 200: 294-302