메뉴 건너뛰기




Volumn 32, Issue 2, 2012, Pages 133-143

S-allyl cysteine mitigates oxidative damage and improves neurologic deficit in a rat model of focal cerebral ischemia

Author keywords

Inflammation; Middle cerebral artery occlusion; Neurobehavior; Oxidative damage; S allyl cysteine

Indexed keywords

CATALASE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INDUCIBLE NITRIC OXIDE SYNTHASE; S ALLYLCYSTEINE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 84863408335     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2011.12.014     Document Type: Article
Times cited : (71)

References (53)
  • 2
    • 71349087001 scopus 로고    scopus 로고
    • Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats
    • Khan M.M., Ishrat T., Ahmad A., Hoda M.N., Khan M.B., Khuwaja G., et al. Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats. Chem Biol Interact 2010, 183:255-263.
    • (2010) Chem Biol Interact , vol.183 , pp. 255-263
    • Khan, M.M.1    Ishrat, T.2    Ahmad, A.3    Hoda, M.N.4    Khan, M.B.5    Khuwaja, G.6
  • 3
    • 79959854853 scopus 로고    scopus 로고
    • Lesion patterns and mechanism of cerebral infarction caused by severe atherosclerotic intracranial internal carotid artery stenosis
    • Chen H., Hong H., Liu D., Xu G., Wang Y., Zeng J., et al. Lesion patterns and mechanism of cerebral infarction caused by severe atherosclerotic intracranial internal carotid artery stenosis. J Neurol Sci 2011, 307:79-85.
    • (2011) J Neurol Sci , vol.307 , pp. 79-85
    • Chen, H.1    Hong, H.2    Liu, D.3    Xu, G.4    Wang, Y.5    Zeng, J.6
  • 4
    • 77449152992 scopus 로고    scopus 로고
    • Oxidative stress and its role in the pathogenesis of ischaemic stroke
    • Allen C.L., Bayraktutan U. Oxidative stress and its role in the pathogenesis of ischaemic stroke. Stroke 2009, 4:461-470.
    • (2009) Stroke , vol.4 , pp. 461-470
    • Allen, C.L.1    Bayraktutan, U.2
  • 5
    • 64349101903 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival
    • Niizuma K., Endo H., Chan P.H. Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival. J Neurochem 2009, 109:133-138.
    • (2009) J Neurochem , vol.109 , pp. 133-138
    • Niizuma, K.1    Endo, H.2    Chan, P.H.3
  • 6
    • 78149335989 scopus 로고    scopus 로고
    • Leonurine protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function
    • Loh K.P., Qi J., Tan B.K., Liu X.H., Wei B.G., Zhu Y.Z. Leonurine protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function. Stroke 2010, 41:2661-2668.
    • (2010) Stroke , vol.41 , pp. 2661-2668
    • Loh, K.P.1    Qi, J.2    Tan, B.K.3    Liu, X.H.4    Wei, B.G.5    Zhu, Y.Z.6
  • 7
    • 61449215012 scopus 로고    scopus 로고
    • Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke
    • Sun M., Zhao Y., Gu Y., Xu Y. Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke. Neurochem Int 2009, 54:339-346.
    • (2009) Neurochem Int , vol.54 , pp. 339-346
    • Sun, M.1    Zhao, Y.2    Gu, Y.3    Xu, Y.4
  • 8
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 9
    • 0031444569 scopus 로고    scopus 로고
    • Reproducibility and reliability of middle cerebral artery occlusion using a silicone-coated suture (Koizumi) in rats
    • Takano K., Tatlisumak Y., Bergmann A.G., Gibson D.G., Fisher M. Reproducibility and reliability of middle cerebral artery occlusion using a silicone-coated suture (Koizumi) in rats. J Neurol Sci 1997, 153:8-11.
    • (1997) J Neurol Sci , vol.153 , pp. 8-11
    • Takano, K.1    Tatlisumak, Y.2    Bergmann, A.G.3    Gibson, D.G.4    Fisher, M.5
  • 13
    • 55849140885 scopus 로고    scopus 로고
    • Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine
    • Garcia E., Limon D., Perez-De V., La Cruz L.a., Giordano M., Diaz-Muñoz M., et al. Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine. Free Radic Res 2008, 42:892-902.
    • (2008) Free Radic Res , vol.42 , pp. 892-902
    • Garcia, E.1    Limon, D.2    Perez-De, V.3    La Cruz, L.4    Giordano, M.5    Diaz-Muñoz, M.6
  • 14
    • 84863416586 scopus 로고    scopus 로고
    • S-allylcysteine, a garlic compound, protects against oxidative stress in 1-methyl-4-phenylpyridinium-induced parkinsonism in mice
    • [Epub ahead of print]
    • Rojas P., Serrano-García N., Medina-Campos O.N., Pedraza-Chaverri J., Maldonado P.D., Ruiz-Sánchez E. S-allylcysteine, a garlic compound, protects against oxidative stress in 1-methyl-4-phenylpyridinium-induced parkinsonism in mice. J Nutr Biochem 2010, [Epub ahead of print].
    • (2010) J Nutr Biochem
    • Rojas, P.1    Serrano-García, N.2    Medina-Campos, O.N.3    Pedraza-Chaverri, J.4    Maldonado, P.D.5    Ruiz-Sánchez, E.6
  • 15
    • 33747840352 scopus 로고    scopus 로고
    • Dietary S-allyl-L-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in stroke-prone spontaneously hypertensive rats
    • Kim J.M., Chang N., Kim W.K., Chun H.S. Dietary S-allyl-L-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in stroke-prone spontaneously hypertensive rats. Biosci Biotechnol Biochem 2006, 70:1969-1971.
    • (2006) Biosci Biotechnol Biochem , vol.70 , pp. 1969-1971
    • Kim, J.M.1    Chang, N.2    Kim, W.K.3    Chun, H.S.4
  • 16
    • 62949141358 scopus 로고    scopus 로고
    • S-allyl l-cysteine diminishes cerebral ischemia-induced mitochondrial dysfunctions in hippocampus
    • Atif F., Yousuf S., Agrawal S.K. S-allyl l-cysteine diminishes cerebral ischemia-induced mitochondrial dysfunctions in hippocampus. Brain Res 2009, 1265:128-137.
    • (2009) Brain Res , vol.1265 , pp. 128-137
    • Atif, F.1    Yousuf, S.2    Agrawal, S.K.3
  • 18
    • 79955464184 scopus 로고    scopus 로고
    • S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type
    • Javed H., Khan M.M., Khan A., Vaibhav K., Ahmad A., Khuwaja G., et al. S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type. Brain Res 2011, 1389:133-142.
    • (2011) Brain Res , vol.1389 , pp. 133-142
    • Javed, H.1    Khan, M.M.2    Khan, A.3    Vaibhav, K.4    Ahmad, A.5    Khuwaja, G.6
  • 19
    • 78049290874 scopus 로고    scopus 로고
    • S-allylcysteine reduces the MPTP-induced striatal cell damage via inhibition of pro-inflammatory cytokine tumor necrosis factor-α and inducible nitric oxide synthase expressions in mice
    • García E., Villeda-Hernández J., Pedraza-Chaverrí J., Maldonado P.D., Santamaría A. S-allylcysteine reduces the MPTP-induced striatal cell damage via inhibition of pro-inflammatory cytokine tumor necrosis factor-α and inducible nitric oxide synthase expressions in mice. Phytomedicine 2010, 18:65-73.
    • (2010) Phytomedicine , vol.18 , pp. 65-73
    • García, E.1    Villeda-Hernández, J.2    Pedraza-Chaverrí, J.3    Maldonado, P.D.4    Santamaría, A.5
  • 20
    • 0030222364 scopus 로고    scopus 로고
    • Attenuation of rat ischemic brain damage by aged garlic extracts: a possible protecting mechanism as antioxidants
    • Numagami Y., Sato S., Ohnishi S.T. Attenuation of rat ischemic brain damage by aged garlic extracts: a possible protecting mechanism as antioxidants. Neurochem Int 1996, 29:135-143.
    • (1996) Neurochem Int , vol.29 , pp. 135-143
    • Numagami, Y.1    Sato, S.2    Ohnishi, S.T.3
  • 22
    • 0029055738 scopus 로고
    • Age related learning deficits in transgenic mice expressing the 721- amino acid isoform of human beta-amyloid precursor protein
    • Moran P.M., Higgins L.S., Cordel B., Moser P.C. Age related learning deficits in transgenic mice expressing the 721- amino acid isoform of human beta-amyloid precursor protein. Proc Natl Acad Sci USA 1995, 92:5341-5345.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5341-5345
    • Moran, P.M.1    Higgins, L.S.2    Cordel, B.3    Moser, P.C.4
  • 23
    • 0002433688 scopus 로고
    • Effects of sulfhydryl reagent on peroxidation in microsomes
    • Utley H.C., Bernhein F., Hochslein P. Effects of sulfhydryl reagent on peroxidation in microsomes. Arch Biochem Biophys 1967, 260:521-531.
    • (1967) Arch Biochem Biophys , vol.260 , pp. 521-531
    • Utley, H.C.1    Bernhein, F.2    Hochslein, P.3
  • 24
    • 0016151122 scopus 로고
    • Bromobenzene induced liver necrosis: protective role of glutathione and evidence for 3, 4-bromobenzene oxide as the hepatotoxic intermediate
    • Jollow D.J., Mitchell J.R., Zampaghone N., Gillete J.R. Bromobenzene induced liver necrosis: protective role of glutathione and evidence for 3, 4-bromobenzene oxide as the hepatotoxic intermediate. Pharmacology 1974, 11:161-169.
    • (1974) Pharmacology , vol.11 , pp. 161-169
    • Jollow, D.J.1    Mitchell, J.R.2    Zampaghone, N.3    Gillete, J.R.4
  • 25
    • 0016808562 scopus 로고
    • Glutathione reductase levels in rat brain
    • Carlberg I., Mannerviek B. Glutathione reductase levels in rat brain. J Biol Chem 1975, 250:5475-5480.
    • (1975) J Biol Chem , vol.250 , pp. 5475-5480
    • Carlberg, I.1    Mannerviek, B.2
  • 26
    • 0021752183 scopus 로고
    • Differential distribution of glutathione and glutathione related enzymes in rabbit kidneys: possible implication in analgesic neuropathy
    • Mohandas J., Marshall J.J., Duggin G.G., Horvath J.S., Tiller D. Differential distribution of glutathione and glutathione related enzymes in rabbit kidneys: possible implication in analgesic neuropathy. Cancer Res 1984, 44:5086-5091.
    • (1984) Cancer Res , vol.44 , pp. 5086-5091
    • Mohandas, J.1    Marshall, J.J.2    Duggin, G.G.3    Horvath, J.S.4    Tiller, D.5
  • 27
    • 0034038502 scopus 로고    scopus 로고
    • Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism and oxidative stress in experimental diabetic neuropathy
    • Stevens M., Obrosova I., Cao X., Huysen C.V., Green D.A. Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism and oxidative stress in experimental diabetic neuropathy. Diabetes 2000, 49:1006-1015.
    • (2000) Diabetes , vol.49 , pp. 1006-1015
    • Stevens, M.1    Obrosova, I.2    Cao, X.3    Huysen, C.V.4    Green, D.A.5
  • 30
    • 33745826332 scopus 로고    scopus 로고
    • Effect of saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats
    • Saleem S., Ahmad M., Ahmad A.S., Yousuf S., Ansari M.A., Khan M.B., et al. Effect of saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats. J Med Food 2006, 9:246-253.
    • (2006) J Med Food , vol.9 , pp. 246-253
    • Saleem, S.1    Ahmad, M.2    Ahmad, A.S.3    Yousuf, S.4    Ansari, M.A.5    Khan, M.B.6
  • 31
    • 0025879020 scopus 로고
    • Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections
    • Schwarting R.K., Bonatz A.E., Carey R.J., Huston J.P. Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections. Brain Res 1991, 554:46-55.
    • (1991) Brain Res , vol.554 , pp. 46-55
    • Schwarting, R.K.1    Bonatz, A.E.2    Carey, R.J.3    Huston, J.P.4
  • 32
    • 49849092361 scopus 로고    scopus 로고
    • Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats
    • Zhao J., Zhao Y., Zheng W., Lu Y., Feng G., Yu S. Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats. Brain Res 2008, 1229:224-232.
    • (2008) Brain Res , vol.1229 , pp. 224-232
    • Zhao, J.1    Zhao, Y.2    Zheng, W.3    Lu, Y.4    Feng, G.5    Yu, S.6
  • 33
    • 78650170987 scopus 로고    scopus 로고
    • Baicalinattenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation
    • Xue X., Qu X.J., Yang Y., Sheng X.H., Cheng F., Jiang E.N., et al. Baicalinattenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation. Biochem Biophys Res Commun 2010, 403:398-404.
    • (2010) Biochem Biophys Res Commun , vol.403 , pp. 398-404
    • Xue, X.1    Qu, X.J.2    Yang, Y.3    Sheng, X.H.4    Cheng, F.5    Jiang, E.N.6
  • 35
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination
    • Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 1986, 17:472-476.
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3    Nishimura, M.C.4    Davis, R.L.5    Bartkowski, H.6
  • 36
    • 33646359238 scopus 로고    scopus 로고
    • Reactive oxygen species: influence on cerebral vascular tone
    • Faraci F.M. Reactive oxygen species: influence on cerebral vascular tone. J Appl Physiol 2006, 100:739-743.
    • (2006) J Appl Physiol , vol.100 , pp. 739-743
    • Faraci, F.M.1
  • 37
    • 84863408936 scopus 로고    scopus 로고
    • Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity
    • Mantha A.K., Moorthy K., Cowsik S.M., Baquer N.Z. Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology 2006, 71:17.
    • (2006) Biogerontology , vol.71 , pp. 17
    • Mantha, A.K.1    Moorthy, K.2    Cowsik, S.M.3    Baquer, N.Z.4
  • 38
    • 65549098614 scopus 로고    scopus 로고
    • Apoptotic mechanisms after cerebral ischemia
    • Broughton B.R., Reutens D.C., Sobey C.G. Apoptotic mechanisms after cerebral ischemia. Stroke 2009, 40:331-339.
    • (2009) Stroke , vol.40 , pp. 331-339
    • Broughton, B.R.1    Reutens, D.C.2    Sobey, C.G.3
  • 39
    • 79961210488 scopus 로고    scopus 로고
    • Quercetin protects against oxidative stress associated damages in a rat model of transient focal cerebral ischemia and reperfusion
    • Ahmad A., Khan M.M., Hoda M.N., Raza S.S., Khan M.B., Javed H., et al. Quercetin protects against oxidative stress associated damages in a rat model of transient focal cerebral ischemia and reperfusion. Neurochem Res 2011, 36:1360-1371.
    • (2011) Neurochem Res , vol.36 , pp. 1360-1371
    • Ahmad, A.1    Khan, M.M.2    Hoda, M.N.3    Raza, S.S.4    Khan, M.B.5    Javed, H.6
  • 40
  • 41
    • 20144386944 scopus 로고    scopus 로고
    • Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences
    • Ahmad M., Saleem S., Ahmad A.S., Yousuf S., Ansari M.N., Khan M.B., et al. Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences. J Neurochem 2005, 93:94-104.
    • (2005) J Neurochem , vol.93 , pp. 94-104
    • Ahmad, M.1    Saleem, S.2    Ahmad, A.S.3    Yousuf, S.4    Ansari, M.N.5    Khan, M.B.6
  • 42
    • 0025248644 scopus 로고
    • The paradox of high risk of stroke in populations with low risk of coronary heart disease
    • Reed D.M. The paradox of high risk of stroke in populations with low risk of coronary heart disease. Am J Epidemiol 1990, 131:579-588.
    • (1990) Am J Epidemiol , vol.131 , pp. 579-588
    • Reed, D.M.1
  • 43
    • 0020427486 scopus 로고
    • Biology of disease: free radicals and tissue injury
    • Freeman B.A., Crapo J.D. Biology of disease: free radicals and tissue injury. Lab Invest 1982, 47:412-426.
    • (1982) Lab Invest , vol.47 , pp. 412-426
    • Freeman, B.A.1    Crapo, J.D.2
  • 44
    • 0035169472 scopus 로고    scopus 로고
    • Effect of chronic treatment of melatonin on learning, memory and oxidative deficiencies induced by intracerebroventricularstreptozotocin in rats
    • Sharma M., Gupta Y.K. Effect of chronic treatment of melatonin on learning, memory and oxidative deficiencies induced by intracerebroventricularstreptozotocin in rats. Pharmacol Biochem Behav 2001, 70:325-331.
    • (2001) Pharmacol Biochem Behav , vol.70 , pp. 325-331
    • Sharma, M.1    Gupta, Y.K.2
  • 45
    • 0038809806 scopus 로고    scopus 로고
    • Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats
    • Kumar V.M.H., Gupta Y.K. Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats. Clin Exp Pharmacol Physiol 2003, 30:336-342.
    • (2003) Clin Exp Pharmacol Physiol , vol.30 , pp. 336-342
    • Kumar, V.M.H.1    Gupta, Y.K.2
  • 46
    • 0033971069 scopus 로고    scopus 로고
    • Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxynitrite generation
    • Imam S.Z., Ali S.F. Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxynitrite generation. Brain Res 2000, 855:186-191.
    • (2000) Brain Res , vol.855 , pp. 186-191
    • Imam, S.Z.1    Ali, S.F.2
  • 47
    • 33748340037 scopus 로고    scopus 로고
    • Antioxidant and neuroprotective effects of hesperidin and its aglyconehesperetin
    • Jungsook C.h.o. Antioxidant and neuroprotective effects of hesperidin and its aglyconehesperetin. Arch Pharm Res 2006, 29:699-706.
    • (2006) Arch Pharm Res , vol.29 , pp. 699-706
    • Jungsook, C.1
  • 48
    • 0037101634 scopus 로고    scopus 로고
    • The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury
    • Basu A., Krady J.K., O'Malley M., Styren S.D., DeKosky S.T., Levison S.W. The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury. J Neurosci 2002, 22:6071-6082.
    • (2002) J Neurosci , vol.22 , pp. 6071-6082
    • Basu, A.1    Krady, J.K.2    O'Malley, M.3    Styren, S.D.4    DeKosky, S.T.5    Levison, S.W.6
  • 49
    • 0030988138 scopus 로고    scopus 로고
    • Nitric oxide synthase in models of focal ischemia
    • Samdani A.F., Dawson T.M., Dawson V.L. Nitric oxide synthase in models of focal ischemia. Stroke 1997, 28:1283-1288.
    • (1997) Stroke , vol.28 , pp. 1283-1288
    • Samdani, A.F.1    Dawson, T.M.2    Dawson, V.L.3
  • 50
    • 33847301419 scopus 로고    scopus 로고
    • Brazilein protects the brain against focal cerebral ischemia reperfusion injury correlating to inflammatory response suppression
    • Shen J., Zhang H., Lin H., Su H., Xing D., Du L. Brazilein protects the brain against focal cerebral ischemia reperfusion injury correlating to inflammatory response suppression. Eur J Pharmacol 2007, 558:88-95.
    • (2007) Eur J Pharmacol , vol.558 , pp. 88-95
    • Shen, J.1    Zhang, H.2    Lin, H.3    Su, H.4    Xing, D.5    Du, L.6
  • 51
    • 79954420117 scopus 로고    scopus 로고
    • Aminoguanidine administration ameliorates hippocampal damage after middle cerebral artery occlusion in rat
    • Danielisova V., Burda J., Nemethova M., Gottlieb M. Aminoguanidine administration ameliorates hippocampal damage after middle cerebral artery occlusion in rat. Neurochem Res 2011, 36:476-486.
    • (2011) Neurochem Res , vol.36 , pp. 476-486
    • Danielisova, V.1    Burda, J.2    Nemethova, M.3    Gottlieb, M.4
  • 52
    • 0037341594 scopus 로고    scopus 로고
    • Normalization of endothelial and inducible nitric oxide synthase expression in brain microvessels of spontaneously hypertensive rats by angiotensin II AT1 receptor inhibition
    • Yamakawa H., Jezova M., Ando H., Saavedra J.M. Normalization of endothelial and inducible nitric oxide synthase expression in brain microvessels of spontaneously hypertensive rats by angiotensin II AT1 receptor inhibition. J Cereb Blood Flow Metab 2003, 23:371-380.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 371-380
    • Yamakawa, H.1    Jezova, M.2    Ando, H.3    Saavedra, J.M.4
  • 53
    • 44349105260 scopus 로고    scopus 로고
    • Malignant alterations following early blockade of nitric oxide synthase in hypertensive rats
    • Hsu Y.H., Hsu B.G., Chen H.I. Malignant alterations following early blockade of nitric oxide synthase in hypertensive rats. Chin J Physiol 2007, 50:283-293.
    • (2007) Chin J Physiol , vol.50 , pp. 283-293
    • Hsu, Y.H.1    Hsu, B.G.2    Chen, H.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.