메뉴 건너뛰기




Volumn 4, Issue 4, 2012, Pages 471-486

HDAC inhibitors for the treatment of cutaneous T-cell lymphomas

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BELINOSTAT; BEXAROTENE; BIOLOGICAL MARKER; BORTEZOMIB; CYTOKINE; DEPSIPEPTIDE; ETOPOSIDE; EVEROLIMUS; FENOFIBRATE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 90 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; NICOTINAMIDE; PANOBINOSTAT; ROMIDEPSIN; STAT PROTEIN; VORINOSTAT;

EID: 84863367140     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.12.6     Document Type: Review
Times cited : (60)

References (93)
  • 1
    • 34447558598 scopus 로고    scopus 로고
    • Incidence of cutaneous T-cell lymphoma in the United States, 1973-2002
    • DOI 10.1001/archderm.143.7.854
    • Criscione VD, Weinstock MA. Incidence of cutaneous T cell lymphoma in the United States, 1973-2002. Arch. Dermatol. 143(7), 854-859 (2007). (Pubitemid 47076482)
    • (2007) Archives of Dermatology , vol.143 , Issue.7 , pp. 854-859
    • Criscione, V.D.1    Weinstock, M.A.2
  • 2
    • 77956270426 scopus 로고    scopus 로고
    • Sezary syndrome and mycosis fungoides arise from distinct T cell subsets: A biologic rationale for their distinct clinical behaviors
    • Campbell JJ, Clark RA, Watanabe R, Kupper TS. Sezary syndrome and mycosis fungoides arise from distinct T cell subsets: a biologic rationale for their distinct clinical behaviors. Blood 116(5), 767-771 (2010).
    • (2010) Blood , vol.116 , Issue.5 , pp. 767-771
    • Campbell, J.J.1    Clark, R.A.2    Watanabe, R.3    Kupper, T.S.4
  • 3
    • 37049008056 scopus 로고    scopus 로고
    • Mycosis Fungoides: Pathophysiology and Emerging Therapies
    • DOI 10.1053/j.seminoncol.2007.01.008, PII S0093775407002254, Purine Nucleoside Phosphorylase (PNP): A Novel Target in Leukemia and Lymphomas
    • Duvic M, Foss FM. Mycosis fungoides: pathophysiology and emerging therapies. Semin. Oncol. 34(6 Suppl. 5), S21-S28 (2007). (Pubitemid 350250800)
    • (2007) Seminars in Oncology , vol.34 , Issue.SUPPL. 5
    • Duvic, M.1    Foss, F.M.2
  • 4
    • 78751571254 scopus 로고    scopus 로고
    • Sézary syndrome: Immunopathogenesis, literature review of therapeutic options, and recommendations for therapy by the United States cutaneous lymphoma consortium (USCLC
    • Olsen EA, Rook AH, Zic J et al. Sézary syndrome: immunopathogenesis, literature review of therapeutic options, and recommendations for therapy by the United States cutaneous lymphoma consortium (USCLC). J. Am. Acad. Dermatol. 64(2), 352-404 (2011).
    • (2011) J. Am. Acad. Dermatol. , vol.64 , Issue.2 , pp. 352-404
    • Olsen, E.A.1    Rook, A.H.2    Zic, J.3
  • 5
    • 45749096959 scopus 로고    scopus 로고
    • Prevalence and treatment of Staphylococcus aureus colonization in patients with mycosis fungoides and Sézary syndrome
    • DOI 10.1111/j.1365-2133.2008.08612.x
    • Talpur R, Bassett R, Duvic M. Prevalence and treatment of Staphylococcus aureus colonization in patients with mycosis fungoides and Sezary syndrome. Br. J. Dermatol. 159(1), 105-112 (2008). (Pubitemid 351874496)
    • (2008) British Journal of Dermatology , vol.159 , Issue.1 , pp. 105-112
    • Talpur, R.1    Bassett, R.2    Duvic, M.3
  • 6
    • 14944370108 scopus 로고    scopus 로고
    • Health-related quality-of-life assessment in patients with cutaneous T-cell lymphoma
    • Demierre MF, Tien A, Miller D. Health related quality-of-life assessment in patients with cutaneous T cell lymphoma. Arch. Dermatol. 141(3), 325-330 (2005). (Pubitemid 40365448)
    • (2005) Archives of Dermatology , vol.141 , Issue.3 , pp. 325-330
    • Demierre, M.-F.1    Tien, A.2    Miller, D.3
  • 8
    • 61349126603 scopus 로고    scopus 로고
    • Overall survival in erythrodermic cutaneous T cell lymphoma: An analysis of prognostic factors in a cohort of patients with erythrodermic cutaneous T cell lymphoma
    • Vidulich KA, Talpur R, Bassett RL, Duvic M. Overall survival in erythrodermic cutaneous T cell lymphoma: an analysis of prognostic factors in a cohort of patients with erythrodermic cutaneous T cell lymphoma. Int. J. Dermatol. 48(3), 243-252 (2009).
    • (2009) Int. J. Dermatol. , vol.48 , Issue.3 , pp. 243-252
    • Vidulich, K.A.1    Talpur, R.2    Bassett, R.L.3    Duvic, M.4
  • 10
    • 16844371989 scopus 로고    scopus 로고
    • Resistance to activation-induced cell death and bystander cytotoxicity via the Fas/Fas ligand pathway are implicated in the pathogenesis of cutaneous T cell lymphomas
    • DOI 10.1111/j.0022-202X.2005.23657.x
    • Ni X, Zhang C, Talpur R, Duvic M. Resistance to activation-induced cell death and bystander cytotoxicity via the Fas/Fas ligand pathway are implicated in the pathogenesis of cutaneous T cell lymphomas. J. Invest. Dermatol. 124(4), 741-750 (2005). (Pubitemid 40489501)
    • (2005) Journal of Investigative Dermatology , vol.124 , Issue.4 , pp. 741-750
    • Ni, X.1    Zhang, C.2    Talpur, R.3    Duvic, M.4
  • 13
    • 0036839480 scopus 로고    scopus 로고
    • Clonal heterogeneity in mycosis fungoides and its relationship to clinical course
    • DOI 10.1182/blood.V100.9.3369
    • Vega F, Luthra R, Medeiros LJ et al. Clonal heterogeneity in mycosis fungoides and its relationship to clinical course. Blood 100(9), 3369-3373 (2002). (Pubitemid 35217089)
    • (2002) Blood , vol.100 , Issue.9 , pp. 3369-3373
    • Vega, F.1    Luthra, R.2    Jeffrey Medeiros, L.3    Dunmire, V.4    Lee, S.-J.5    Duvic, M.6    Jones, D.7
  • 18
    • 73949149251 scopus 로고    scopus 로고
    • Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T cell lymphoma
    • Piekarz RL, Frye R, Turner M et al. Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T cell lymphoma. J. Clin. Oncol. 27(32), 5410-5417 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.32 , pp. 5410-5417
    • Piekarz, R.L.1    Frye, R.2    Turner, M.3
  • 19
    • 77952503384 scopus 로고    scopus 로고
    • Total skin electron beam and non-myeloablative allogeneic hematopoietic stem-cell transplantation in advanced mycosis fungoides and Sezary syndrome
    • Duvic M, Donato M, Dabaja B et al. Total skin electron beam and non-myeloablative allogeneic hematopoietic stem-cell transplantation in advanced mycosis fungoides and Sezary syndrome. J. Clin. Oncol. 28(14), 2365-2372 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.14 , pp. 2365-2372
    • Duvic, M.1    Donato, M.2    Dabaja, B.3
  • 20
    • 34548091879 scopus 로고    scopus 로고
    • Systemic monotherapy vs combination therapy for CTCL: Rationale and future strategies
    • Duvic M. Systemic monotherapy vs combination therapy for CTCL: rationale and future strategies. Oncology (Williston Park). 21(2 Suppl. 1), 33-40 (2007).
    • (2007) Oncology (Williston Park , vol.21 , Issue.2 SUPPL. 1 , pp. 33-40
    • Duvic, M.1
  • 22
    • 78649304686 scopus 로고    scopus 로고
    • Role of histone deacetylases and their inhibitors in cancer biology and treatment
    • Beumer JH, Tawbi H. Role of histone deacetylases and their inhibitors in cancer biology and treatment. Curr. Clin. Pharmacol. 5(3), 196-208 (2010).
    • (2010) Curr. Clin. Pharmacol. , vol.5 , Issue.3 , pp. 196-208
    • Beumer, J.H.1    Tawbi, H.2
  • 23
    • 77955581767 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Advancing therapeutic strategies in hematological and solid malignancies
    • Ellis L, Pili R. Histone deacetylase inhibitors: advancing therapeutic strategies in hematological and solid malignancies. Pharmaceuticals (Basel) 3(8), 2411-2469 (2010).
    • (2010) Pharmaceuticals (Basel , vol.3 , Issue.8 , pp. 2411-2469
    • Ellis, L.1    Pili, R.2
  • 24
    • 78650848615 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in the treatment of lymphoma
    • Lemoine M, Younes A. Histone deacetylase inhibitors in the treatment of lymphoma. Discov. Med. 10(54), 462-470 (2010).
    • (2010) Discov. Med. , vol.10 , Issue.54 , pp. 462-470
    • Lemoine, M.1    Younes, A.2
  • 25
    • 50049108874 scopus 로고    scopus 로고
    • Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T cell lymphoma
    • Marquard L, Gjerdrum LM, Christensen IJ, Jensen PB, Sehested M, Ralfkiaer E. Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T cell lymphoma. Histopathology 53(3), 267-277 (2008).
    • (2008) Histopathology , vol.53 , Issue.3 , pp. 267-277
    • Marquard, L.1    Gjerdrum, L.M.2    Christensen, I.J.3    Jensen, P.B.4    Sehested, M.5    Ralfkiaer, E.6
  • 26
    • 67349160499 scopus 로고    scopus 로고
    • HDAC expression and clinical prognosis in human malignancies
    • Weichert W. HDAC expression and clinical prognosis in human malignancies. Cancer Lett. 280(2), 168-176 (2009).
    • (2009) Cancer Lett. , vol.280 , Issue.2 , pp. 168-176
    • Weichert, W.1
  • 28
    • 68949212379 scopus 로고    scopus 로고
    • Lysine acetylation targets protein complexes and co-regulates major cellular functions
    • Choudhary C, Kumar C, Gnad F et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325(5942), 834-840 (2009).
    • (2009) Science , vol.325 , Issue.5942 , pp. 834-840
    • Choudhary, C.1    Kumar, C.2    Gnad, F.3
  • 29
    • 36048958965 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Overview and perspectives
    • DOI 10.1158/1541-7786.MCR-07-0324
    • Dokmanovic M, Clarke C, Marks PA. Histone deacetylase inhibitors: overview and perspectives. Mol. Cancer Res. 5(10), 981-989 (2007). (Pubitemid 350080267)
    • (2007) Molecular Cancer Research , vol.5 , Issue.10 , pp. 981-989
    • Dokmanovic, M.1    Clarke, C.2    Marks, P.A.3
  • 30
    • 78651361884 scopus 로고    scopus 로고
    • Targeting histone deacetyalses in the treatment of B- and T cell malignancies
    • Zain J, O'Connor OA. Targeting histone deacetyalses in the treatment of B- and T cell malignancies. Invest. New Drugs 28(Suppl. 1), S58-S78 (2010).
    • (2010) Invest. New Drugs , vol.28 , Issue.SUPPL. 1
    • Zain, J.1    O'Connor, O.A.2
  • 31
    • 0033520944 scopus 로고    scopus 로고
    • Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects
    • Sambucetti LC, Fischer DD, Zabludoff S et al. Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J. Biol. Chem. 274(49), 34940-34947 (1999). (Pubitemid 129509542)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.49 , pp. 34940-34947
    • Sambucetti, L.C.1    Fischer, D.D.2    Zabludoff, S.3    Kwon, P.O.4    Chamberlin, H.5    Trogani, N.6    Xu, H.7    Cohen, D.8
  • 32
    • 0033822112 scopus 로고    scopus 로고
    • P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228
    • Sandor V, Senderowicz A, Mertins S et al. P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228. Br. J. Cancer. 83(6), 817-825 (2000).
    • (2000) Br. J. Cancer. , vol.83 , Issue.6 , pp. 817-825
    • Sandor, V.1    Senderowicz, A.2    Mertins, S.3
  • 33
    • 33644814867 scopus 로고    scopus 로고
    • Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T cell lymphoma cells: Relevance to mechanism of therapeutic action
    • Zhang C, Richon V, Ni X, Talpur R, Duvic M. Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T cell lymphoma cells: relevance to mechanism of therapeutic action. J. Invest. Dermatol. 125(5), 1045-1052 (2005).
    • (2005) J. Invest. Dermatol. , vol.125 , Issue.5 , pp. 1045-1052
    • Zhang, C.1    Richon, V.2    Ni, X.3    Talpur, R.4    Duvic, M.5
  • 34
    • 54049093249 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Apoptotic effects and clinical implications (review
    • Emanuele S, Lauricella M, Tesoriere G. Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review). Int. J. Oncol. 33(4), 637-646 (2008).
    • (2008) Int. J. Oncol. , vol.33 , Issue.4 , pp. 637-646
    • Emanuele, S.1    Lauricella, M.2    Tesoriere, G.3
  • 35
    • 79955148265 scopus 로고    scopus 로고
    • Cancer cells' epigenetic composition and predisposition to histone deacetylase inhibitor sensitization
    • Nalabothula N, Carrier F. Cancer cells' epigenetic composition and predisposition to histone deacetylase inhibitor sensitization. Epigenomics 3(2), 145-155 (2011).
    • (2011) Epigenomics , vol.3 , Issue.2 , pp. 145-155
    • Nalabothula, N.1    Carrier, F.2
  • 36
    • 67651121842 scopus 로고    scopus 로고
    • The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy
    • Ellis L, Bots M, Lindemann RK et al. The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy. Blood 114(2), 380-393 (2009).
    • (2009) Blood , vol.114 , Issue.2 , pp. 380-393
    • Ellis, L.1    Bots, M.2    Lindemann, R.K.3
  • 37
    • 77956636838 scopus 로고    scopus 로고
    • Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T cell lymphoma models: Defining molecular mechanisms of resistance
    • Shao W, Growney JD, Feng Y et al. Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T cell lymphoma models: defining molecular mechanisms of resistance. Int. J. Cancer 127(9), 2199-2208 (2010).
    • (2010) Int. J. Cancer , vol.127 , Issue.9 , pp. 2199-2208
    • Shao, W.1    Growney, J.D.2    Feng, Y.3
  • 39
    • 84876092645 scopus 로고    scopus 로고
    • Targeting apoptosis proteins in hematological malignancies
    • 10.1016/j.canlet.2011.06.016 Epub ahead of print).
    • Droin N, Guery L, Benikhlef N, Solary E. Targeting apoptosis proteins in hematological malignancies. Cancer Lett. 30, 30 doi:10.1016/j.canlet.2011.06.016 (2011) (Epub ahead of print).
    • (2011) Cancer Lett. , vol.30 , pp. 30
    • Droin, N.1    Guery, L.2    Benikhlef, N.3    Solary, E.4
  • 40
    • 79952270884 scopus 로고    scopus 로고
    • HDACs link the DNA damage response, processing of double-strand breaks and autophagy
    • Robert T, Vanoli F, Chiolo I et al. HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature 471(7336), 74-79 (2011).
    • (2011) Nature , vol.471 , Issue.7336 , pp. 74-79
    • Robert, T.1    Vanoli, F.2    Chiolo, I.3
  • 43
    • 79959301511 scopus 로고    scopus 로고
    • Function of histone deacetylase inhibitors in inflammation
    • Grabiec AM, Tak PP, Reedquist KA. Function of histone deacetylase inhibitors in inflammation. Crit. Rev. Immunol. 31(3), 233-263 (2011).
    • (2011) Crit. Rev. Immunol. , vol.31 , Issue.3 , pp. 233-263
    • Grabiec, A.M.1    Tak, P.P.2    Reedquist, K.A.3
  • 44
    • 84863376264 scopus 로고    scopus 로고
    • Phase II study of oral panobinostat (LBH589), a potent pan-deacetylase inhibitor, in patients with refractory cutaneous T cell lymphoma (CTCL
    • Chicago, IL, USA, 20 May Poster 8555
    • Duvic M, Vanaclocha F, Bernengo MG et al. Phase II study of oral panobinostat (LBH589), a potent pan-deacetylase inhibitor, in patients with refractory cutaneous T cell lymphoma (CTCL). Presented at: ASCO American Society of Clinical Oncology Meeting. Chicago, IL, USA, 20 May 2008 (Poster 8555).
    • (2008) Presented at: ASCO American Society of Clinical Oncology Meeting
    • Duvic, M.1    Vanaclocha, F.2    Bernengo, M.G.3
  • 45
    • 77954504404 scopus 로고    scopus 로고
    • Final results of a Phase II trial of belinostat (PXD101) in patients with recurrent or refractory peripheral or cutaneous T cell lymphoma
    • New Orleans, LA, USA, 8 December Poster 3453
    • Pohlman B, Advani R, Duvic M et al. Final results of a Phase II trial of belinostat (PXD101) in patients with recurrent or refractory peripheral or cutaneous T cell lymphoma. Presented at: ASH Annual Meeting and Expositions. New Orleans, LA, USA, 8 December 2009 (Poster 3453).
    • (2009) Presented at: ASH Annual Meeting and Expositions
    • Pohlman, B.1    Advani, R.2    Duvic, M.3
  • 46
    • 33846122993 scopus 로고    scopus 로고
    • Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
    • DOI 10.1038/nbt1272, PII NBT1272
    • Marks PA, Breslow R. Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug. Nat. Biotechnol. 25(1), 84-90 (2007). (Pubitemid 46087907)
    • (2007) Nature Biotechnology , vol.25 , Issue.1 , pp. 84-90
    • Marks, P.A.1    Breslow, R.2
  • 47
    • 20444479514 scopus 로고    scopus 로고
    • Drug insight: Histone deacetylase inhibitors - Development of the new targeted anticancer agent suberoylanilide hydroxamic acid
    • DOI 10.1038/ncponc0106
    • Kelly WK, Marks PA. Drug insight: histone deacetylase inhibitors - development of the new targeted anticancer agent suberoylanilide hydroxamic acid. Nat. Clin. Pract. Oncol. 2(3), 150-157 (2005). (Pubitemid 40823166)
    • (2005) Nature Clinical Practice Oncology , vol.2 , Issue.3 , pp. 150-157
    • Kelly, W.K.1    Marks, P.A.2
  • 48
    • 77249087051 scopus 로고    scopus 로고
    • Chemical phylogenetics of histone deacetylases
    • Bradner JE, West N, Grachan ML et al. Chemical phylogenetics of histone deacetylases. Nat. Chem. Biol. 6(3), 238-243 (2010).
    • (2010) Nat. Chem. Biol. , vol.6 , Issue.3 , pp. 238-243
    • Bradner, J.E.1    West, N.2    Grachan, M.L.3
  • 49
    • 73949128107 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy
    • Lane AA, Chabner BA. Histone deacetylase inhibitors in cancer therapy. J. Clin. Oncol. 27(32), 5459-5468 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.32 , pp. 5459-5468
    • Lane, A.A.1    Chabner, B.A.2
  • 51
    • 77957091318 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair
    • Lee JH, Choy ML, Ngo L, Foster SS, Marks PA. Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair. Proc. Natl Acad. Sci. USA 107(33), 14639-14644 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.33 , pp. 14639-14644
    • Lee, J.H.1    Choy, M.L.2    Ngo, L.3    Foster, S.S.4    Marks, P.A.5
  • 54
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: Outer membrane permeabilization and beyond
    • Tait SW, Green DR. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat. Rev. Mol. Cell Biol. 11(9), 621-632 (2010).
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , Issue.9 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 55
    • 0035525783 scopus 로고    scopus 로고
    • Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T cell lymphoma cells
    • Qin JZ, Zhang CL, Kamarashev J, Dummer R, Burg G, Dobbeling U. Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T cell lymphoma cells. Blood 98(9), 2778-2783 (2001).
    • (2001) Blood , vol.98 , Issue.9 , pp. 2778-2783
    • Qin, J.Z.1    Zhang, C.L.2    Kamarashev, J.3    Dummer, R.4    Burg, G.5    Dobbeling, U.6
  • 56
    • 45549083112 scopus 로고    scopus 로고
    • Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T cell lymphoma
    • Fantin VR, Loboda A, Paweletz CP et al. Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T cell lymphoma. Cancer Res. 68(10), 3785-3794 (2008).
    • (2008) Cancer Res. , vol.68 , Issue.10 , pp. 3785-3794
    • Fantin, V.R.1    Loboda, A.2    Paweletz, C.P.3
  • 57
    • 79952394059 scopus 로고    scopus 로고
    • The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expressionin cutaneous T-cell lymphoma cells
    • Tiffon C, Adams J, Van der Fits L et al. The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expressionin cutaneous T-cell lymphoma cells. Br. J. Pharmacol. 162(7), 1590-1602 (2011).
    • (2011) Br. J. Pharmacol. , vol.162 , Issue.7 , pp. 1590-1602
    • Tiffon, C.1    Adams, J.2    Van Der Fits, L.3
  • 58
    • 46449091277 scopus 로고    scopus 로고
    • Molecular Mechanisms and Therapeutic Development of Angiogenesis Inhibitors
    • DOI 10.1016/S0065-230X(08)00004-3, PII S0065230X08000043
    • Cao Y. Molecular mechanisms and therapeutic development of angiogenesis inhibitors. Adv. Cancer Res. 100, 113-131 (2008). (Pubitemid 351932181)
    • (2008) Advances in Cancer Research , vol.100 , pp. 113-131
    • Cao, Y.1
  • 59
    • 58049208190 scopus 로고    scopus 로고
    • Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis
    • Fotheringham S, Epping MT, Stimson L et al. Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis. Cancer Cell 15(1), 57-66 (2009).
    • (2009) Cancer Cell , vol.15 , Issue.1 , pp. 57-66
    • Fotheringham, S.1    Epping, M.T.2    Stimson, L.3
  • 60
    • 77950877402 scopus 로고    scopus 로고
    • HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy
    • Khan O, Fotheringham S, Wood V et al. HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy. Proc. Natl Acad. Sci. USA 107(14), 6532-6537 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.14 , pp. 6532-6537
    • Khan, O.1    Fotheringham, S.2    Wood, V.3
  • 61
    • 72549108624 scopus 로고    scopus 로고
    • Evaluation of the long-term tolerability and clinical benefit of vorinostat in patients with advanced cutaneous T cell lymphoma
    • Duvic M, Olsen EA, Breneman D et al. Evaluation of the long-term tolerability and clinical benefit of vorinostat in patients with advanced cutaneous T cell lymphoma. Clin. Lymphoma Myeloma 9(6), 412-416 (2009).
    • (2009) Clin. Lymphoma Myeloma , vol.9 , Issue.6 , pp. 412-416
    • Duvic, M.1    Olsen, E.A.2    Breneman, D.3
  • 63
    • 0344431240 scopus 로고    scopus 로고
    • FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor
    • DOI 10.1006/excr.1998.4027
    • Nakajima H, Kim YB, Terano H, Yoshida M, Horinouchi S. FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor. Exp. Cell Res. 241(1), 126-133 (1998). (Pubitemid 28366586)
    • (1998) Experimental Cell Research , vol.241 , Issue.1 , pp. 126-133
    • Nakajima, H.1    Kim, Y.B.2    Terano, H.3    Yoshida, M.4    Horinouchi, S.5
  • 65
    • 2942535832 scopus 로고    scopus 로고
    • T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: Impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance
    • DOI 10.1182/blood-2003-09-3068
    • Piekarz RL, Robey RW, Zhan Z et al. T cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance. Blood 103(12), 4636-4643 (2004). (Pubitemid 38745996)
    • (2004) Blood , vol.103 , Issue.12 , pp. 4636-4643
    • Piekarz, R.L.1    Robey, R.W.2    Zhan, Z.3    Kayastha, G.4    Sayah, A.5    Abdeldaim, A.H.6    Torrico, S.7    Bates, S.E.8
  • 67
    • 0035525781 scopus 로고    scopus 로고
    • Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T cell lymphoma: A case report
    • Piekarz RL, Robey R, Sandor V et al. Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T cell lymphoma: a case report. Blood 98(9), 2865-2868 (2001).
    • (2001) Blood , vol.98 , Issue.9 , pp. 2865-2868
    • Piekarz, R.L.1    Robey, R.2    Sandor, V.3
  • 68
    • 77954879663 scopus 로고    scopus 로고
    • Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T cell lymphoma
    • Whittaker SJ, Demierre MF, Kim EJ et al. Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T cell lymphoma. J. Clin. Oncol. 28(29), 4485-4491 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.29 , pp. 4485-4491
    • Whittaker, S.J.1    Demierre, M.F.2    Kim, E.J.3
  • 71
    • 72649091422 scopus 로고    scopus 로고
    • Laboratory correlates for a Phase II trial of romidepsin in cutaneous and peripheral T cell lymphoma
    • Bates SE, Zhan Z, Steadman K et al. Laboratory correlates for a Phase II trial of romidepsin in cutaneous and peripheral T cell lymphoma. Br. J. Haematol. 148(2), 256-267 (2010).
    • (2010) Br. J. Haematol. , vol.148 , Issue.2 , pp. 256-267
    • Bates, S.E.1    Zhan, Z.2    Steadman, K.3
  • 72
    • 79959611523 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic properties of an oral formulation of the histone deacetylase inhibitor Belinostat (PXD101
    • Steele NL, Plumb JA, Vidal L et al. Pharmacokinetic and pharmacodynamic properties of an oral formulation of the histone deacetylase inhibitor Belinostat (PXD101). Cancer Chemother. Pharmacol. 67(6), 1273-1279 (2011).
    • (2011) Cancer Chemother. Pharmacol. , vol.67 , Issue.6 , pp. 1273-1279
    • Steele, N.L.1    Plumb, J.A.2    Vidal, L.3
  • 73
    • 1642453460 scopus 로고    scopus 로고
    • Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101
    • Plumb JA, Finn PW, Williams RJ et al. Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101. Mol. Cancer Ther. 2(8), 721-728 (2003).
    • (2003) Mol. Cancer Ther. , vol.2 , Issue.8 , pp. 721-728
    • Plumb, J.A.1    Finn, P.W.2    Williams, R.J.3
  • 74
    • 80052255348 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor belinostat represses survivin expression through reactivation of TGF{b} receptor II leading to cancer cell death
    • Chowdhury S, Howell GM, Teggart CA et al. The histone deacetylase inhibitor belinostat represses survivin expression through reactivation of TGF{b} receptor II leading to cancer cell death. J. Biol. Chem. 286(35), 30937-30948 (2011).
    • (2011) J. Biol. Chem. , vol.286 , Issue.35 , pp. 30937-30948
    • Chowdhury, S.1    Howell, G.M.2    Teggart, C.A.3
  • 75
    • 77954167626 scopus 로고    scopus 로고
    • A Phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours
    • Lassen U, Molife LR, Sorensen M et al. A Phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours. Br. J. Cancer. 103(1), 12-17 (2010).
    • (2010) Br. J. Cancer. , vol.103 , Issue.1 , pp. 12-17
    • Lassen, U.1    Molife, L.R.2    Sorensen, M.3
  • 77
    • 49349104503 scopus 로고    scopus 로고
    • A Phase I clinical trial of the histone deacetylase inhibitor belinostat in patients with advanced hematological neoplasia
    • Gimsing P, Hansen M, Knudsen LM et al. A Phase I clinical trial of the histone deacetylase inhibitor belinostat in patients with advanced hematological neoplasia. Eur. J. Haematol. 81(3), 170-176 (2008).
    • (2008) Eur. J. Haematol. , vol.81 , Issue.3 , pp. 170-176
    • Gimsing, P.1    Hansen, M.2    Knudsen, L.M.3
  • 78
    • 69849110970 scopus 로고    scopus 로고
    • Panobinostat (LBH589): A potent pan-deacetylase inhibitor with promising activity against hematologic and solid tumors
    • Prince HM, Bishton MJ, Johnstone RW. Panobinostat (LBH589): a potent pan-deacetylase inhibitor with promising activity against hematologic and solid tumors. Future Oncol. 5(5), 601-612 (2009).
    • (2009) Future Oncol. , vol.5 , Issue.5 , pp. 601-612
    • Prince, H.M.1    Bishton, M.J.2    Johnstone, R.W.3
  • 79
    • 65449134812 scopus 로고    scopus 로고
    • Cotreatment with BCL-2 antagonist sensitizes cutaneous T cell lymphoma to lethal action of HDAC7-Nur77-based mechanism
    • Chen J, Fiskus W, Eaton K et al. Cotreatment with BCL-2 antagonist sensitizes cutaneous T cell lymphoma to lethal action of HDAC7-Nur77-based mechanism. Blood 113(17), 4038-4048 (2009).
    • (2009) Blood , vol.113 , Issue.17 , pp. 4038-4048
    • Chen, J.1    Fiskus, W.2    Eaton, K.3
  • 80
    • 51649126841 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T cell lymphoma
    • Ellis L, Pan Y, Smyth GK et al. Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T cell lymphoma. Clin. Cancer Res. 14(14), 4500-4510 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.14 , pp. 4500-4510
    • Ellis, L.1    Pan, Y.2    Smyth, G.K.3
  • 81
    • 79952697614 scopus 로고    scopus 로고
    • Potentiation of apoptosis by histone deacetylase inhibitors and doxorubicin combination: Cytoplasmic cathepsin B as a mediator of apoptosis in multiple myeloma
    • Cheriyath V, Kuhns MA, Kalaycio ME, Borden EC. Potentiation of apoptosis by histone deacetylase inhibitors and doxorubicin combination: cytoplasmic cathepsin B as a mediator of apoptosis in multiple myeloma. Br. J. Cancer 104(6), 957-967 (2011).
    • (2011) Br. J. Cancer , vol.104 , Issue.6 , pp. 957-967
    • Cheriyath, V.1    Kuhns, M.A.2    Kalaycio, M.E.3    Borden, E.C.4
  • 82
    • 79952100628 scopus 로고    scopus 로고
    • The synergistic effect of panobinostat (LBH589) with melphalan or doxorubicin on multiple myeloma cells; Rationale for the use of combination regimens in myeloma patients
    • Terpos E. The synergistic effect of panobinostat (LBH589) with melphalan or doxorubicin on multiple myeloma cells; rationale for the use of combination regimens in myeloma patients. Leuk. Res. 35(3), 295-296 (2011).
    • (2011) Leuk. Res. , vol.35 , Issue.3 , pp. 295-296
    • Terpos, E.1
  • 83
    • 58849158362 scopus 로고    scopus 로고
    • Valproic acid and all-trans-retinoic acid: Meta-analysis of a palliative treatment regimen in AML and MDS patients
    • Bellos F, Mahlknecht U. Valproic acid and all-trans-retinoic acid: meta-analysis of a palliative treatment regimen in AML and MDS patients. Onkologie 31(11), 629-633 (2008).
    • (2008) Onkologie , vol.31 , Issue.11 , pp. 629-633
    • Bellos, F.1    Mahlknecht, U.2
  • 84
    • 77958610266 scopus 로고    scopus 로고
    • Novel chemoradiosensitizers for cancer therapy
    • Page P, Yang LX. Novel chemoradiosensitizers for cancer therapy. Anticancer Res. 30(9), 3675-3682 (2010).
    • (2010) Anticancer Res. , vol.30 , Issue.9 , pp. 3675-3682
    • Page, P.1    Yang, L.X.2
  • 85
    • 84863339701 scopus 로고    scopus 로고
    • Vorinostat in combination with bexarotene in advanced cutaneous T cell lymphoma: A phase I study
    • Orlando FL USA 20 May Poster 8572
    • Dummer R, Hymes K, Sterry W et al. Vorinostat in combination with bexarotene in advanced cutaneous T cell lymphoma: a Phase I study. Presented at: ASCO American Society of Clinical Oncology Meeting. Orlando, FL, USA, 20 May 2009 (Poster 8572).
    • (2009) Presented at: ASCO American Society of Clinical Oncology Meeting
    • Dummer, R.1    Hymes, K.2    Sterry, W.3
  • 86
    • 41849085137 scopus 로고    scopus 로고
    • Complete clinical remission of tumor-stage mycosis fungoides after acute extensive skin necroses, granulomatous reaction, and fever under treatment with bexarotene, vorinostat, and high-dose fenofibrate
    • DOI 10.1016/j.jaad.2007.07.012, PII S0190962207011322
    • Steinhoff M, Beyer M, Roewert-Huber J et al. Complete clinical remission of tumor-stage mycosis fungoides after acute extensive skin necroses, granulomatous reaction, and fever under treatment with bexarotene, vorinostat, and high-dose fenofibrate. J. Am. Acad. Dermatol. 58(5 Suppl. 1), S88-S91 (2008). (Pubitemid 351503635)
    • (2008) Journal of the American Academy of Dermatology , vol.58 , Issue.SUPPL. 1
    • Steinhoff, M.1    Beyer, M.2    Roewert-Huber, J.3    Lukowsky, A.4    Assaf, C.5    Sterry, W.6
  • 88
    • 80052903833 scopus 로고    scopus 로고
    • The efficacy of vorinostat in combination with interferon alpha and extracorporeal photopheresis in late stage mycosis fungoides and Sézary syndrome
    • Sanli H, Akay BN, Anadolu R, Ozcan M, Saral S, Akyol A. The efficacy of vorinostat in combination with interferon alpha and extracorporeal photopheresis in late stage mycosis fungoides and Sézary syndrome. J. Drugs Dermatol. 10(4), 403-408 (2011).
    • (2011) J. Drugs Dermatol. , vol.10 , Issue.4 , pp. 403-408
    • Sanli, H.1    Akay, B.N.2    Anadolu, R.3    Ozcan, M.4    Saral, S.5    Akyol, A.6
  • 89
    • 65349116082 scopus 로고    scopus 로고
    • Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in cutaneous T cell lymphoma
    • Heider U, Rademacher J, Lamottke B et al. Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in cutaneous T cell lymphoma. Eur. J. Haematol. 82(6), 440-449 (2009).
    • (2009) Eur. J. Haematol. , vol.82 , Issue.6 , pp. 440-449
    • Heider, U.1    Rademacher, J.2    Lamottke, B.3
  • 90
    • 68749093915 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib interacts synergistically with the histone deacetylase inhibitor suberoylanilide hydroxamic acid to induce T-leukemia/lymphoma cells apoptosis
    • Zhang QL, Wang L, Zhang YW et al. The proteasome inhibitor bortezomib interacts synergistically with the histone deacetylase inhibitor suberoylanilide hydroxamic acid to induce T-leukemia/lymphoma cells apoptosis. Leukemia 23(8), 1507-1514 (2009).
    • (2009) Leukemia , vol.23 , Issue.8 , pp. 1507-1514
    • Zhang, Q.L.1    Wang, L.2    Zhang, Y.W.3
  • 91
    • 77950644059 scopus 로고    scopus 로고
    • Vorinostat interferes with the signaling transduction pathway of T cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T cell lymphoma
    • Wozniak MB, Villuendas R, Bischoff JR et al. Vorinostat interferes with the signaling transduction pathway of T cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T cell lymphoma. Haematologica 95(4), 613-621 (2010).
    • (2010) Haematologica , vol.95 , Issue.4 , pp. 613-621
    • Wozniak, M.B.1    Villuendas, R.2    Bischoff, J.R.3
  • 92
    • 33845514708 scopus 로고    scopus 로고
    • Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?
    • DOI 10.1038/sj.leu.2404464, PII 2404464
    • Karagiannis TC, El-Osta A. Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds? Leukemia 21(1), 61-65 (2007). (Pubitemid 44921835)
    • (2007) Leukemia , vol.21 , Issue.1 , pp. 61-65
    • Karagiannis, T.C.1    El-Osta, A.2
  • 93
    • 77955261645 scopus 로고    scopus 로고
    • Benefits of vorinostat in treating advanced cutaneous T-cell lymphoma
    • Zhang CL, Duvic M. Benefits of vorinostat in treating advanced cutaneous T-cell lymphoma. US Oncol. 5(1), 27-31 (2009).
    • (2009) US Oncol. , vol.5 , Issue.1 , pp. 27-31
    • Zhang, C.L.1    Duvic, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.