-
1
-
-
79953086675
-
Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41
-
Anastassopoulou CG, et al. 2011. Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41. Virology 413:47-59.
-
(2011)
Virology
, vol.413
, pp. 47-59
-
-
Anastassopoulou, C.G.1
-
2
-
-
70049098271
-
Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry
-
Berro R, Sanders RW, Lu M, Klasse PJ, Moore JP. 2009. Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry. PLoS Pathog. 5:e1000548.
-
(2009)
PLoS Pathog
, vol.5
-
-
Berro, R.1
Sanders, R.W.2
Lu, M.3
Klasse, P.J.4
Moore, J.P.5
-
3
-
-
0029955497
-
The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection
-
DOI 10.1038/nm1196-1244
-
Cocchi F, et al. 1996. The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection. Nat. Med. 2:1244-1247. (Pubitemid 26375410)
-
(1996)
Nature Medicine
, vol.2
, Issue.11
, pp. 1244-1247
-
-
Cocchi, F.1
DeVico, A.L.2
Garzino-Demo, A.3
Cara, A.4
Gallo, R.C.5
Lusso, P.6
-
4
-
-
0036333648
-
The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor
-
DOI 10.1128/JVI.76.17.8953-8957.2002
-
Cormier EG, Dragic T. 2002. The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor. J. Virol. 76:8953-8957. (Pubitemid 34864089)
-
(2002)
Journal of Virology
, vol.76
, Issue.17
, pp. 8953-8957
-
-
Cormier, E.G.1
Dragic, T.2
-
5
-
-
13044263875
-
Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes
-
DOI 10.1073/pnas.96.21.12004
-
Gonzalez E, et al. 1999. Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes. Proc. Natl. Acad. Sci. U. S. A. 96:12004-12009. (Pubitemid 29502848)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.21
, pp. 12004-12009
-
-
Gonzalez, E.1
Bamshad, M.2
Sato, N.3
Mummidi, S.4
Dhanda, R.5
Catano, G.6
Cabrera, S.7
McBride, M.8
Cao, X.-H.9
Merrill, G.10
O'Connell, P.11
Bowden, D.W.12
Freedman, B.I.13
Anderson, S.A.14
Walter, E.A.15
Evans, J.S.16
Stephan, K.T.17
Clark, R.A.18
Tyagi, S.19
Ahuja, S.S.20
Dolan, M.J.21
Ahuja, S.K.22
more..
-
6
-
-
34347379935
-
Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-infected, treatment-experienced patients: AIDS clinical trials group 5211
-
DOI 10.1086/518797
-
Gulick RM, et al. 2007. Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-infected, treatment-experienced patients: AIDS clinical trials group 5211. J. Infect. Dis. 196:304-312. (Pubitemid 47047471)
-
(2007)
Journal of Infectious Diseases
, vol.196
, Issue.2
, pp. 304-312
-
-
Gulick, R.M.1
Su, Z.2
Flexner, C.3
Hughes, M.D.4
Skolnik, P.R.5
Wilkin, T.J.6
Gross, R.7
Krambrink, A.8
Coakley, E.9
Greaves, W.L.10
Zolopa, A.11
Reichman, R.12
Godfrey, C.13
Hirsch, M.14
Kuritzkes, D.R.15
-
7
-
-
78650236401
-
Evolution of CCR5 antagonist resistance in an HIV-1 subtype C clinical isolate
-
Henrich TJ, et al. 2010. Evolution of CCR5 antagonist resistance in an HIV-1 subtype C clinical isolate. J. Acquir. Immune Defic. Syndr. 55:420-427.
-
(2010)
J. Acquir. Immune Defic. Syndr.
, vol.55
, pp. 420-427
-
-
Henrich, T.J.1
-
8
-
-
34848868199
-
Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
-
Huang CC, et al. 2007. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science 317: 1930-1934.
-
(2007)
Science
, vol.317
, pp. 1930-1934
-
-
Huang, C.C.1
-
9
-
-
27744597054
-
Structure of a V3-containing HIV-1 gp120 core
-
Huang CC, et al. 2005. Structure of a V3-containing HIV-1 gp120 core. Science 310:1025-1028.
-
(2005)
Science
, vol.310
, pp. 1025-1028
-
-
Huang, C.C.1
-
10
-
-
34249336735
-
High throughput functional analysis of HIV-1 env genes without cloning
-
DOI 10.1016/j.jviromet.2007.02.015, PII S0166093407000924
-
Kirchherr JL, et al. 2007. High throughput functional analysis of HIV-1 env genes without cloning. J. Virol. Methods 143:104-111. (Pubitemid 46813163)
-
(2007)
Journal of Virological Methods
, vol.143
, Issue.1
, pp. 104-111
-
-
Kirchherr, J.L.1
Lu, X.2
Kasongo, W.3
Chalwe, V.4
Mwananyanda, L.5
Musonda, R.M.6
Xia, S.-M.7
Scearce, R.M.8
Liao, H.-X.9
Montefiori, D.C.10
Haynes, B.F.11
Gao, F.12
-
11
-
-
12144289333
-
Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor
-
DOI 10.1128/JVI.78.6.2790-2807.2004
-
Kuhmann SE, et al. 2004. Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor. J. Virol. 78:2790-2807. (Pubitemid 38314338)
-
(2004)
Journal of Virology
, vol.78
, Issue.6
, pp. 2790-2807
-
-
Kuhmann, S.E.1
Pugach, P.2
Kunstman, K.J.3
Taylor, J.4
Stanfield, R.L.5
Snyder, A.6
Strizki, J.M.7
Riley, J.8
Baroudy, B.M.9
Wilson, I.A.10
Korber, B.T.11
Wolinsky, S.M.12
Moore, J.P.13
-
12
-
-
77956185778
-
The design and validation of a novel phenotypic assay to determine HIV-1 coreceptor usage of clinical isolates
-
Lin NH, et al. The design and validation of a novel phenotypic assay to determine HIV-1 coreceptor usage of clinical isolates. J. Virol. Methods 169:39-46.
-
J. Virol. Methods
, vol.169
, pp. 39-46
-
-
Lin, N.H.1
-
13
-
-
20644453529
-
Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D)
-
DOI 10.1016/j.virol.2005.04.035, PII S0042682205002564
-
Marozsan AJ, et al. 2005. Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D). Virology 338:182-199. (Pubitemid 40835936)
-
(2005)
Virology
, vol.338
, Issue.1
, pp. 182-199
-
-
Marozsan, A.J.1
Kuhmann, S.E.2
Morgan, T.3
Herrera, C.4
Rivera-Troche, E.5
Xu, S.6
Baroudy, B.M.7
Strizki, J.8
Moore, J.P.9
-
14
-
-
0032484088
-
Genetic acceleration of AIDS progression by a promoter variant of CCR5
-
Martin MP, et al. 1998. Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science 282:1907-1911.
-
(1998)
Science
, vol.282
, pp. 1907-1911
-
-
Martin, M.P.1
-
15
-
-
79951810774
-
Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1)
-
McNicholas PM, et al. 2011. Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1). J. Acquir. Immune Defic. Syndr. 56:222-229.
-
(2011)
J. Acquir. Immune Defic. Syndr.
, vol.56
, pp. 222-229
-
-
McNicholas, P.M.1
-
16
-
-
0031181196
-
Host Genes and HIV: The Role of the Chemokine Receptor Gene CCR5 and Its Allele (delta32 CCR5)
-
McNicholl JM, Smith DK, Qari SH, Hodge T. 1997. Host genes and HIV: the role of the chemokine receptor gene CCR5 and its allele (delta 32 CCR5). Emerg. Infect. Dis. 3:261-271. (Pubitemid 127431686)
-
(1997)
Emerging Infectious Diseases
, vol.3
, Issue.3
, pp. 261-271
-
-
McNicholl, J.M.1
Smith, D.K.2
Qari, S.H.3
Hodge, T.4
-
17
-
-
70450170953
-
Structure-function analysis of human immunodeficiency virus type 1 gp120 amino acid mutations associated with resistance to the CCR5 coreceptor antagonist vicriviroc
-
Ogert RA, et al. 2009. Structure-function analysis of human immunodeficiency virus type 1 gp120 amino acid mutations associated with resistance to the CCR5 coreceptor antagonist vicriviroc. J. Virol. 83:12151-12163.
-
(2009)
J. Virol.
, vol.83
, pp. 12151-12163
-
-
Ogert, R.A.1
-
18
-
-
77649188640
-
Clinical resistance to vicriviroc through adaptive V3 loop mutations in HIV-1 subtype D gp120 that alter interactions with the N terminus and ECL2 of CCR5
-
Ogert RA, et al. 2010. Clinical resistance to vicriviroc through adaptive V3 loop mutations in HIV-1 subtype D gp120 that alter interactions with the N terminus and ECL2 of CCR5. Virology 400:145-155.
-
(2010)
Virology
, vol.400
, pp. 145-155
-
-
Ogert, R.A.1
-
19
-
-
77953305009
-
HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+T cells
-
Pfaff JM, et al. 2010. HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+T cells. J. Virol. 84:6505-6514.
-
(2010)
J. Virol.
, vol.84
, pp. 6505-6514
-
-
Pfaff, J.M.1
-
20
-
-
84863116880
-
HIV-1 clinical isolates resistant to CCR5 antagonists exhibit delayed entry kinetics that correct in the presence of drug
-
Putcharoen O, et al. 2011. HIV-1 clinical isolates resistant to CCR5 antagonists exhibit delayed entry kinetics that correct in the presence of drug. J. Virol. 86:1119-1128.
-
(2011)
J. Virol.
, vol.86
, pp. 1119-1128
-
-
Putcharoen, O.1
-
21
-
-
79955398621
-
HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less efficient mechanism of gp120-CCR5 engagement that attenuates macrophage-tropism
-
Roche M, et al. 2012. HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less efficient mechanism of gp120-CCR5 engagement that attenuates macrophage-tropism. J. Virol. 85:4330-4342.
-
(2012)
J. Virol.
, vol.85
, pp. 4330-4342
-
-
Roche, M.1
-
22
-
-
76449113232
-
HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry
-
Tilton JC, et al. 2010. HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry. AIDS Res. Hum. Retroviruses 26:13-24.
-
(2010)
AIDS Res. Hum. Retroviruses
, vol.26
, pp. 13-24
-
-
Tilton, J.C.1
-
23
-
-
77957204794
-
A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5
-
Tilton JC, et al. 2010. A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5. J. Virol. 84:10863-10876.
-
(2010)
J. Virol.
, vol.84
, pp. 10863-10876
-
-
Tilton, J.C.1
-
24
-
-
34047148544
-
Chemokine antagonists as therapeutics: Focus on HIV-1
-
DOI 10.1146/annurev.med.58.080105.102908
-
Tsibris AM, Kuritzkes DR. 2007. Chemokine antagonists as therapeutics: focus on HIV-1. Annu. Rev. Med. 58:445-459. (Pubitemid 46706526)
-
(2007)
Annual Review of Medicine
, vol.58
, pp. 445-459
-
-
Tsibris, A.M.N.1
Kuritzkes, D.R.2
-
25
-
-
49149118151
-
In vivo emergence of vicriviroc resistance in a human immunodeficiency virus type 1 subtype C-infected subject
-
Tsibris AM, et al. 2008. In vivo emergence of vicriviroc resistance in a human immunodeficiency virus type 1 subtype C-infected subject. J. Virol. 82:8210-8214.
-
(2008)
J. Virol.
, vol.82
, pp. 8210-8214
-
-
Tsibris, A.M.1
-
26
-
-
33847237614
-
Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry
-
Westby M, et al. 2007. Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry. J. Virol. 81: 2359-2371.
-
(2007)
J. Virol.
, vol.81
, pp. 2359-2371
-
-
Westby, M.1
-
27
-
-
77955006578
-
Three-year safety and efficacy of vicriviroc, a CCR5 antagonist, in HIV-1-infected treatment-experienced patients
-
Wilkin TJ, et al. 2010. Three-year safety and efficacy of vicriviroc, a CCR5 antagonist, in HIV-1-infected treatment-experienced patients. J. Acquir. Immune Defic. Syndr. 54:470-476.
-
(2010)
J. Acquir. Immune Defic. Syndr.
, vol.54
, pp. 470-476
-
-
Wilkin, T.J.1
-
28
-
-
24044454355
-
Isolation of TAK-779-resistant HIV-1 from an R5 HIV-1 GP120 V3 loop library
-
DOI 10.1074/jbc.M414360200
-
Yusa K, Maeda Y, Fujioka A, Monde K, Harada S. 2005. Isolation of TAK-779-resistant HIV-1 from an R5 HIV-1 GP120 V3 loop library. J. Biol. Chem. 280:30083-30090. (Pubitemid 41216184)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.34
, pp. 30083-30090
-
-
Yusa, K.1
Maeda, Y.2
Fujioka, A.3
Monde, K.4
Harada, S.5
|