Regulation of cyclooxygenase-2 and cytosolic phospholipase A 2 gene expression by lipopolysaccharide through the RNA-binding protein HuR: Involvement of NADPH oxidase, reactive oxygen species and mitogen-activated protein kinases

British Journal of Pharmacology

Volumn 163, Issue 8, 2011, Pages 1691-1706

  Lin, Wei Ning ^a   Lin, Chih Chung ^b   Cheng, Hsin Yi ^c   Yang, Chuen Mao ^c  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

COX 2; cPLA 2; human tracheal smooth muscle cells; HuR; lipopolysaccharide

Indexed keywords

CYCLOOXYGENASE 2; HU ANTIGEN; HU ANTIGEN R; LIPOPOLYSACCHARIDE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE A2; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NUCLEOTIDE SEQUENCE; OXIDATIVE PHOSPHORYLATION; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

CELL CULTURE TECHNIQUES; CYCLOOXYGENASE 2; DINOPROSTONE; GENE EXPRESSION REGULATION; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; PHOSPHOLIPASES A2, CYTOSOLIC; REACTIVE OXYGEN SPECIES; RNA; SIGNAL TRANSDUCTION; TRACHEA;

EID: 79960919004     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01312.x     Document Type: Article

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